Receptors, Glucocorticoid
"Receptors, Glucocorticoid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cytoplasmic proteins that specifically bind glucocorticoids and mediate their cellular effects. The glucocorticoid receptor-glucocorticoid complex acts in the nucleus to induce transcription of DNA. Glucocorticoids were named for their actions on blood glucose concentration, but they have equally important effects on protein and fat metabolism. Cortisol is the most important example.
| Descriptor ID |
D011965
|
| MeSH Number(s) |
D12.776.826.750.430
|
| Concept/Terms |
Receptors, Glucocorticoid- Receptors, Glucocorticoid
- Receptors, Glucocorticoids
- Glucocorticoids Receptors
- Glucocorticoid Receptors
- Glucocorticoid Receptor
- Receptor, Glucocorticoid
Receptors, Corticoid Type II- Receptors, Corticoid Type II
- Corticoid Type II Receptors
- Corticoid II Receptor
- Receptor, Corticoid II
- Receptors, Corticoid II
- Corticoid II Receptors
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Glucocorticoid".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Glucocorticoid".
This graph shows the total number of publications written about "Receptors, Glucocorticoid" by people in this website by year, and whether "Receptors, Glucocorticoid" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 1 | 0 | 1 |
| 2001 | 2 | 1 | 3 |
| 2002 | 1 | 1 | 2 |
| 2003 | 1 | 1 | 2 |
| 2004 | 2 | 0 | 2 |
| 2006 | 2 | 2 | 4 |
| 2007 | 1 | 0 | 1 |
| 2008 | 2 | 3 | 5 |
| 2009 | 2 | 3 | 5 |
| 2010 | 1 | 0 | 1 |
| 2011 | 3 | 2 | 5 |
| 2012 | 3 | 0 | 3 |
| 2013 | 3 | 0 | 3 |
| 2014 | 3 | 1 | 4 |
| 2015 | 4 | 1 | 5 |
| 2016 | 2 | 0 | 2 |
| 2017 | 5 | 1 | 6 |
| 2018 | 3 | 1 | 4 |
| 2019 | 1 | 1 | 2 |
| 2020 | 2 | 0 | 2 |
| 2022 | 1 | 2 | 3 |
| 2024 | 2 | 1 | 3 |
To return to the timeline,
click here.
Below are the most recent publications written about "Receptors, Glucocorticoid" by people in Profiles.
-
A Phase I Trial of Enzalutamide Plus Selective Glucocorticoid Receptor Modulator Relacorilant in Patients with Metastatic Castration-Resistant Prostate Cancer. Clin Cancer Res. 2024 Jun 03; 30(11):2384-2392.
-
Glucocorticoid receptor-mediated oncogenic activity is dependent on breast cancer subtype. J Steroid Biochem Mol Biol. 2024 Oct; 243:106518.
-
Glucocorticoid Receptor (GR) Activation Is Associated with Increased cAMP/PKA Signaling in Castration-Resistant Prostate Cancer. Mol Cancer Ther. 2024 Apr 02; 23(4):552-563.
-
Overcoming Taxane Resistance: Preclinical and Phase 1 Studies of Relacorilant, a Selective Glucocorticoid Receptor Modulator, with Nab-Paclitaxel in Solid Tumors. Clin Cancer Res. 2022 08 02; 28(15):3214-3224.
-
Phase I/II Trial of Enzalutamide and Mifepristone, a Glucocorticoid Receptor Antagonist, for Metastatic Castration-Resistant Prostate Cancer. Clin Cancer Res. 2022 04 14; 28(8):1549-1559.
-
Intermittent glucocorticoid treatment enhances skeletal muscle performance through sexually dimorphic mechanisms. J Clin Invest. 2022 03 15; 132(6).
-
Prospective association of maternal immune pro-inflammatory responsivity and regulation in pregnancy with length of gestation. Am J Reprod Immunol. 2021 05; 85(5):e13366.
-
The Selective Progesterone Receptor Modulator Ulipristal Acetate Inhibits the Activity of the Glucocorticoid Receptor. J Clin Endocrinol Metab. 2020 03 01; 105(3).
-
Glucocorticoid receptor modulation decreases ER-positive breast cancer cell proliferation and suppresses wild-type and mutant ER chromatin association. Breast Cancer Res. 2019 07 24; 21(1):82.
-
Developmental exposure to the endocrine disruptor tolylfluanid induces sex-specific later-life metabolic dysfunction. Reprod Toxicol. 2019 10; 89:74-82.