 Toll-Like Receptor 2
"Toll-Like Receptor 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A pattern recognition receptor that forms heterodimers with other TOLL-LIKE RECEPTORS. It interacts with multiple ligands including PEPTIDOGLYCAN, bacterial LIPOPROTEINS, lipoarabinomannan, and a variety of PORINS.
| Descriptor ID |
D051195
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| MeSH Number(s) |
D12.776.543.750.705.910.500.200
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Toll-Like Receptor 2".
Below are MeSH descriptors whose meaning is more specific than "Toll-Like Receptor 2".
This graph shows the total number of publications written about "Toll-Like Receptor 2" by people in this website by year, and whether "Toll-Like Receptor 2" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 2002 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2007 | 1 | 1 | 2 | | 2010 | 2 | 1 | 3 | | 2011 | 3 | 1 | 4 | | 2012 | 1 | 1 | 2 | | 2013 | 1 | 0 | 1 | | 2015 | 0 | 1 | 1 | | 2017 | 2 | 0 | 2 | | 2018 | 0 | 1 | 1 | | 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Toll-Like Receptor 2" by people in Profiles.
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Mishra P, Hirsch E. Variable Responsiveness to Agonists for TLR2 and TLR7 in Myometrial Cells from Different Sources: Correlation with Receptor Expression. Reprod Sci. 2020 04; 27(4):996-1001.
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Meisel M, Hinterleitner R, Pacis A, Chen L, Earley ZM, Mayassi T, Pierre JF, Ernest JD, Galipeau HJ, Thuille N, Bouziat R, Buscarlet M, Ringus DL, Wang Y, Li Y, Dinh V, Kim SM, McDonald BD, Zurenski MA, Musch MW, Furtado GC, Lira SA, Baier G, Chang EB, Eren AM, Weber CR, Busque L, Godley LA, Verdú EF, Barreiro LB, Jabri B. Microbial signals drive pre-leukaemic myeloproliferation in a Tet2-deficient host. Nature. 2018 05; 557(7706):580-584.
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Ryu KA, McGonnigal B, Moore T, Kargupta T, Mancini RJ, Esser-Kahn AP. Light Guided In-vivo Activation of Innate Immune Cells with Photocaged TLR 2/6 Agonist. Sci Rep. 2017 08 14; 7(1):8074.
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Kellogg RA, Tian C, Etzrodt M, Tay S. Cellular Decision Making by Non-Integrative Processing of TLR Inputs. Cell Rep. 2017 04 04; 19(1):125-135.
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Bhattacharyya S, Ghosh SK, Shokeen B, Eapan B, Lux R, Kiselar J, Nithianantham S, Young A, Pandiyan P, McCormick TS, Weinberg A. FAD-I, a Fusobacterium nucleatum Cell Wall-Associated Diacylated Lipoprotein That Mediates Human Beta Defensin 2 Induction through Toll-Like Receptor-1/2 (TLR-1/2) and TLR-2/6. Infect Immun. 2016 05; 84(5):1446-1456.
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Agrawal V, Jaiswal MK, Mallers T, Katara GK, Gilman-Sachs A, Beaman KD, Hirsch E. Altered autophagic flux enhances inflammatory responses during inflammation-induced preterm labor. Sci Rep. 2015 Mar 23; 5:9410.
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Chiu IM, Heesters BA, Ghasemlou N, Von Hehn CA, Zhao F, Tran J, Wainger B, Strominger A, Muralidharan S, Horswill AR, Bubeck Wardenburg J, Hwang SW, Carroll MC, Woolf CJ. Bacteria activate sensory neurons that modulate pain and inflammation. Nature. 2013 Sep 05; 501(7465):52-7.
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Agrawal V, Smart K, Jilling T, Hirsch E. Surfactant protein (SP)-A suppresses preterm delivery and inflammation via TLR2. PLoS One. 2013; 8(5):e63990.
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Ranoa DR, Kelley SL, Tapping RI. Human lipopolysaccharide-binding protein (LBP) and CD14 independently deliver triacylated lipoproteins to Toll-like receptor 1 (TLR1) and TLR2 and enhance formation of the ternary signaling complex. J Biol Chem. 2013 Apr 05; 288(14):9729-41.
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Ma D, Jin S, Li E, Doi Y, Parajuli B, Noda M, Sonobe Y, Mizuno T, Suzumura A. The neurotoxic effect of astrocytes activated with toll-like receptor ligands. J Neuroimmunol. 2013 Jan 15; 254(1-2):10-8.
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