"Valinomycin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cyclododecadepsipeptide ionophore antibiotic produced by Streptomyces fulvissimus and related to the enniatins. It is composed of 3 moles each of L-valine, D-alpha-hydroxyisovaleric acid, D-valine, and L-lactic acid linked alternately to form a 36-membered ring. (From Merck Index, 11th ed) Valinomycin is a potassium selective ionophore and is commonly used as a tool in biochemical studies.
| Descriptor ID |
D014634
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| MeSH Number(s) |
D04.345.566.297.500 D12.644.641.297.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Valinomycin".
Below are MeSH descriptors whose meaning is more specific than "Valinomycin".
This graph shows the total number of publications written about "Valinomycin" by people in this website by year, and whether "Valinomycin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "Valinomycin" by people in Profiles.
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Motor deficits are triggered by reperfusion-reoxygenation injury as diagnosed by MRI and by a mechanism involving oxidants. J Neurosci. 2012 Apr 18; 32(16):5500-9.
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Antibiotic assisted molecular ion transport across a membrane in real time. Faraday Discuss. 2005; 129:291-9; discussion 353-66.
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Tetrapandins, a new class of scorpion toxins that specifically inhibit store-operated calcium entry in human embryonic kidney-293 cells. J Biol Chem. 2004 Jan 09; 279(2):1040-9.
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Import of transcription factor MTF1 into the yeast mitochondria takes place through an unusual pathway. J Biol Chem. 1995 May 19; 270(20):11970-6.
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Calcium-mediated cyclic AMP inhibition of Na-H exchange in small intestine. Am J Physiol. 1987 Mar; 252(3 Pt 1):C315-22.
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Regulation of active amino acid transport by growth-related changes in membrane potential in a human fibroblast. J Biol Chem. 1978 Nov 25; 253(22):8257-62.