"Macrocyclic Compounds" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cyclic compounds with a ring size of approximately 1-4 dozen atoms.
| Descriptor ID |
D047028
|
| MeSH Number(s) |
D04.345
|
| Concept/Terms |
Macrocyclic Compounds- Macrocyclic Compounds
- Compounds, Macrocyclic
- Macrocycle Compounds
- Compounds, Macrocycle
|
Below are MeSH descriptors whose meaning is more general than "Macrocyclic Compounds".
Below are MeSH descriptors whose meaning is more specific than "Macrocyclic Compounds".
This graph shows the total number of publications written about "Macrocyclic Compounds" by people in this website by year, and whether "Macrocyclic Compounds" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2014 | 2 | 0 | 2 |
| 2019 | 1 | 0 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Macrocyclic Compounds" by people in Profiles.
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Discovery of Thioether-Cyclized Macrocyclic Covalent Inhibitors by mRNA Display. J Am Chem Soc. 2024 Aug 28; 146(34):24053-24060.
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Versatile Peptide Macrocyclization with Diels-Alder Cycloadditions. J Am Chem Soc. 2019 10 16; 141(41):16374-16381.
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An interferon-free antiviral regimen for HCV after liver transplantation. N Engl J Med. 2014 Dec 18; 371(25):2375-82.
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Anti-diabetic activity of insulin-degrading enzyme inhibitors mediated by multiple hormones. Nature. 2014 Jul 03; 511(7507):94-8.
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Ryanodine receptors in human pancreatic beta cells: localization and effects on insulin secretion. FASEB J. 2004 May; 18(7):878-80.
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Selective restoration of calcium coupling to muscarinic M(3) receptors in contractile cultured airway myocytes. Am J Physiol Lung Cell Mol Physiol. 2000 May; 278(5):L1091-100.