 Isothiocyanates
"Isothiocyanates" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Organic compounds with the general formula R-NCS.
| Descriptor ID |
D017879
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| MeSH Number(s) |
D02.500.375 D02.886.250
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Isothiocyanates".
Below are MeSH descriptors whose meaning is more specific than "Isothiocyanates".
This graph shows the total number of publications written about "Isothiocyanates" by people in this website by year, and whether "Isothiocyanates" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1984 | 0 | 1 | 1 | | 1988 | 0 | 1 | 1 | | 2006 | 1 | 0 | 1 | | 2012 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Isothiocyanates" by people in Profiles.
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Folkard DL, Melchini A, Traka MH, Al-Bakheit A, Saha S, Mulholland F, Watson A, Mithen RF. Suppression of LPS-induced transcription and cytokine secretion by the dietary isothiocyanate sulforaphane. Mol Nutr Food Res. 2014 Dec; 58(12):2286-96.
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Traka MH, Melchini A, Mithen RF. Sulforaphane and prostate cancer interception. Drug Discov Today. 2014 Sep; 19(9):1488-92.
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Velmurugan GV, Sundaresan NR, Gupta MP, White C. Defective Nrf2-dependent redox signalling contributes to microvascular dysfunction in type 2 diabetes. Cardiovasc Res. 2013 Oct 01; 100(1):143-50.
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Kensler TW, Egner PA, Agyeman AS, Visvanathan K, Groopman JD, Chen JG, Chen TY, Fahey JW, Talalay P. Keap1-nrf2 signaling: a target for cancer prevention by sulforaphane. Top Curr Chem. 2013; 329:163-77.
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Melchini A, Traka MH, Catania S, Miceli N, Taviano MF, Maimone P, Francisco M, Mithen RF, Costa C. Antiproliferative activity of the dietary isothiocyanate erucin, a bioactive compound from cruciferous vegetables, on human prostate cancer cells. Nutr Cancer. 2013; 65(1):132-8.
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Melchini A, Needs PW, Mithen RF, Traka MH. Enhanced in vitro biological activity of synthetic 2-(2-pyridyl) ethyl isothiocyanate compared to natural 4-(methylsulfinyl) butyl isothiocyanate. J Med Chem. 2012 Nov 26; 55(22):9682-92.
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Loganathan S, Kandala PK, Gupta P, Srivastava SK. Inhibition of EGFR-AKT axis results in the suppression of ovarian tumors in vitro and in preclinical mouse model. PLoS One. 2012; 7(8):e43577.
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Agyeman AS, Chaerkady R, Shaw PG, Davidson NE, Visvanathan K, Pandey A, Kensler TW. Transcriptomic and proteomic profiling of KEAP1 disrupted and sulforaphane-treated human breast epithelial cells reveals common expression profiles. Breast Cancer Res Treat. 2012 Feb; 132(1):175-87.
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Traka MH, Spinks CA, Doleman JF, Melchini A, Ball RY, Mills RD, Mithen RF. The dietary isothiocyanate sulforaphane modulates gene expression and alternative gene splicing in a PTEN null preclinical murine model of prostate cancer. Mol Cancer. 2010 Jul 13; 9:189.
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Chambers KF, Bacon JR, Kemsley EK, Mills RD, Ball RY, Mithen RF, Traka MH. Gene expression profile of primary prostate epithelial and stromal cells in response to sulforaphane or iberin exposure. Prostate. 2009 Sep 15; 69(13):1411-21.
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