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Stephen C. Meredith

TitleProfessor
InstitutionUniversity of Chicago
DepartmentPathology
AddressChicago IL 60637
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Srivastava AK, Venkata BS, Sweat YY, Rizzo HR, Zuo L, Kurgan KW, Moore P, Shashikanth N, Smok I, Sachleben JR, Turner JR, Meredith SC, Jean-François L. Serine 408 phosphorylation is a molecular switch that regulates structure and function of the occludin a-helical bundle. Proc Natl Acad Sci U S A. 2022 08 23; 119(34):e2204618119. PMID: 35969745; PMCID: PMC9407527.
      Citations: 3     Fields:    Translation:AnimalsCells
    2. Wickramasinghe A, Xiao Y, Kobayashi N, Wang S, Scherpelz KP, Yamazaki T, Meredith SC, Ishii Y. Sensitivity-Enhanced Solid-State NMR Detection of Structural Differences and Unique Polymorphs in Pico- to Nanomolar Amounts of Brain-Derived and Synthetic 42-Residue Amyloid-ß Fibrils. J Am Chem Soc. 2021 08 04; 143(30):11462-11472. PMID: 34308630; PMCID: PMC10279877.
      Citations: 11     Fields:    Translation:HumansCells
    3. Natesh SR, Hummels AR, Sachleben JR, Sosnick TR, Freed KF, Douglas JF, Meredith SC, Haddadian EJ. Molecular dynamics study of water channels in natural and synthetic amyloid-ß fibrils. J Chem Phys. 2021 Jun 21; 154(23):235102. PMID: 34241272; PMCID: PMC8214467.
      Citations:    Fields:    Translation:Cells
    4. Pittman JM, Srivastava AK, Boughter CT, Venkata BS, Zerweck J, Moore PC, Smok I, Tonelli M, Sachleben JR, Meredith SC. Nanodroplet Oligomers (NanDOs) of Aß40. Biochemistry. 2021 09 14; 60(36):2691-2703. PMID: 34029056.
      Citations: 3     Fields:    Translation:Humans
    5. Scherpelz KP, Wang S, Pytel P, Madhurapantula RS, Srivastava AK, Sachleben JR, Orgel J, Ishii Y, Meredith SC. Atomic-level differences between brain parenchymal- and cerebrovascular-seeded Aß fibrils. Sci Rep. 2021 01 08; 11(1):247. PMID: 33420184; PMCID: PMC7794565.
      Citations: 5     Fields:    Translation:HumansCells
    6. Dougherty U, Mustafi R, Zhu H, Zhu X, Deb D, Meredith SC, Ayaloglu-Butun F, Fletcher M, Sanchez A, Pekow J, Deng Z, Amini N, Konda VJ, Rao VL, Sakuraba A, Kwesi A, Kupfer SS, Fichera A, Joseph L, Hart J, He F, He TC, West-Szymanski D, Li YC, Bissonnette M. Upregulation of polycistronic microRNA-143 and microRNA-145 in colonocytes suppresses colitis and inflammation-associated colon cancer. Epigenetics. 2021 12; 16(12):1317-1334. PMID: 33356812; PMCID: PMC8813074.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    7. He Y, Schreiber K, Wolf SP, Wen F, Steentoft C, Zerweck J, Steiner M, Sharma P, Shepard HM, Posey A, June CH, Mandel U, Clausen H, Leisegang M, Meredith SC, Kranz DM, Schreiber H. Multiple cancer-specific antigens are targeted by a chimeric antigen receptor on a single cancer cell. JCI Insight. 2019 Dec 05; 4(23). PMID: 31801912; PMCID: PMC6962012.
      Citations: 12     Fields:    
    8. Hawk LML, Pittman JM, Moore PC, Srivastava AK, Zerweck J, Williams JTB, Hawk AJ, Sachleben JR, Meredith SC. ß-amyloid model core peptides: Effects of hydrophobes and disulfides. Protein Sci. 2020 02; 29(2):527-541. PMID: 31710741; PMCID: PMC6954707.
      Citations: 4     Fields:    
    9. He Y, Schreiber K, Wolf SP, Wen F, Steentoft C, Zerweck J, Steiner M, Sharma P, Shepard HM, Posey A, June CH, Mandel U, Clausen H, Meredith SC, Kranz DM, Schreiber H, Leisegang M. Multiple cancer-specific antigens are targeted by a chimeric antigen receptor on a single cancer cell. JCI Insight. 2019 11 01; 4(21). PMID: 31672936; PMCID: PMC6948763.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    10. Srivastava AK, Pittman JM, Zerweck J, Venkata BS, Moore PC, Sachleben JR, Meredith SC. ß-Amyloid aggregation and heterogeneous nucleation. Protein Sci. 2019 09; 28(9):1567-1581. PMID: 31276610; PMCID: PMC6699094.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    11. Zerweck J, Venkata BS, Pittman JM, Srivastava AK, Moore PC, Sachleben JR, Thinakaran G, Meredith SC. A versatile method for producing labeled or unlabeled Aß55, Aß40, and other ß-amyloid family peptides. Protein Expr Purif. 2019 10; 162:72-82. PMID: 31022450.
      Citations:    Fields:    Translation:Cells
    12. Graham WV, He W, Marchiando AM, Zha J, Singh G, Li HS, Biswas A, Ong MLDM, Jiang ZH, Choi W, Zuccola H, Wang Y, Griffith J, Wu J, Rosenberg HJ, Wang Y, Snapper SB, Ostrov D, Meredith SC, Miller LW, Turner JR. Intracellular MLCK1 diversion reverses barrier loss to restore mucosal homeostasis. Nat Med. 2019 04; 25(4):690-700. PMID: 30936544; PMCID: PMC6461392.
      Citations: 71     Fields:    Translation:HumansAnimalsCells
    13. Poellmann MJ, Sosnick TR, Meredith SC, Lee RC. The Pentablock Amphiphilic Copolymer T1107 Prevents Aggregation of Denatured and Reduced Lysozyme. Macromol Biosci. 2017 02; 17(2). PMID: 27615730; PMCID: PMC5497315.
      Citations: 3     Fields:    Translation:AnimalsCells
    14. Johnson EC, Lanning JD, Meredith SC. Peptide backbone modification in the bend region of amyloid-ß inhibits fibrillogenesis but not oligomer formation. J Pept Sci. 2016 May; 22(5):368-73. PMID: 27114096; PMCID: PMC5458744.
      Citations: 2     Fields:    Translation:Cells
    15. Roy S, Ly D, Castro CD, Li NS, Hawk AJ, Altman JD, Meredith SC, Piccirilli JA, Moody DB, Adams EJ. Molecular Analysis of Lipid-Reactive Vd1 ?d T Cells Identified by CD1c Tetramers. J Immunol. 2016 Feb 15; 196(4):1933-42. PMID: 26755823; PMCID: PMC4744554.
      Citations: 52     Fields:    Translation:HumansCells
    16. Scherpelz KP, Lu JX, Tycko R, Meredith SC. Preparation of Amyloid Fibrils Seeded from Brain and Meninges. Methods Mol Biol. 2016; 1345:299-312. PMID: 26453221; PMCID: PMC6326079.
      Citations: 8     Fields:    Translation:HumansAnimals
    17. Do TD, Chamas A, Zheng X, Meredith SC, Shea JE, Bowers MT, Barnes A, Chang D, Veldstra T, Takhar H, Dressler N, Trapp B, Miller K, McMahon A, Lazar Cantrell K. Elucidation of the Aggregation Pathways of Helix-Turn-Helix Peptides: Stabilization at the Turn Region Is Critical for Fibril Formation. Biochemistry. 2015 Jul 07; 54(26):4050-62. PMID: 26070092; PMCID: PMC4526104.
      Citations: 4     Fields:    Translation:HumansCells
    18. Yue MM, Lv K, Meredith SC, Martindale JL, Gorospe M, Schuger L. Novel RNA-binding protein P311 binds eukaryotic translation initiation factor 3 subunit b (eIF3b) to promote translation of transforming growth factor ß1-3 (TGF-ß1-3). J Biol Chem. 2014 Dec 05; 289(49):33971-83. PMID: 25336651; PMCID: PMC4256334.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    19. Dominguez L, Foster L, Meredith SC, Straub JE, Thirumalai D. Structural heterogeneity in transmembrane amyloid precursor protein homodimer is a consequence of environmental selection. J Am Chem Soc. 2014 Jul 09; 136(27):9619-26. PMID: 24926593; PMCID: PMC4105063.
      Citations: 22     Fields:    Translation:Cells
    20. King JV, Liang WG, Scherpelz KP, Schilling AB, Meredith SC, Tang WJ. Molecular basis of substrate recognition and degradation by human presequence protease. Structure. 2014 Jul 08; 22(7):996-1007. PMID: 24931469; PMCID: PMC4128088.
      Citations: 19     Fields:    Translation:HumansCells
    21. Dominguez L, Meredith SC, Straub JE, Thirumalai D. Transmembrane fragment structures of amyloid precursor protein depend on membrane surface curvature. J Am Chem Soc. 2014 Jan 22; 136(3):854-7. PMID: 24364734; PMCID: PMC3928069.
      Citations: 23     Fields:    Translation:Cells
    22. Lu JX, Qiang W, Yau WM, Schwieters CD, Meredith SC, Tycko R. Molecular structure of ß-amyloid fibrils in Alzheimer's disease brain tissue. Cell. 2013 Sep 12; 154(6):1257-68. PMID: 24034249; PMCID: PMC3814033.
      Citations: 518     Fields:    Translation:Humans
    23. Engels B, Engelhard VH, Sidney J, Sette A, Binder DC, Liu RB, Kranz DM, Meredith SC, Rowley DA, Schreiber H. Relapse or eradication of cancer is predicted by peptide-major histocompatibility complex affinity. Cancer Cell. 2013 Apr 15; 23(4):516-26. PMID: 23597565; PMCID: PMC3658176.
      Citations: 84     Fields:    Translation:HumansAnimalsCells
    24. Distler MG, Plant LD, Sokoloff G, Hawk AJ, Aneas I, Wuenschell GE, Termini J, Meredith SC, Nobrega MA, Palmer AA. Glyoxalase 1 increases anxiety by reducing GABAA receptor agonist methylglyoxal. J Clin Invest. 2012 Jun; 122(6):2306-15. PMID: 22585572; PMCID: PMC3366407.
      Citations: 68     Fields:    Translation:Animals
    25. Sandstrom A, Scharf L, McRae G, Hawk AJ, Meredith SC, Adams EJ. ?d T cell receptors recognize the non-classical major histocompatibility complex (MHC) molecule T22 via conserved anchor residues in a MHC peptide-like fashion. J Biol Chem. 2012 Feb 17; 287(8):6035-43. PMID: 22215668; PMCID: PMC3285370.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    26. Cloe AL, Orgel JP, Sachleben JR, Tycko R, Meredith SC. The Japanese mutant Aß (?E22-Aß(1-39)) forms fibrils instantaneously, with low-thioflavin T fluorescence: seeding of wild-type Aß(1-40) into atypical fibrils by ?E22-Aß(1-39). Biochemistry. 2011 Mar 29; 50(12):2026-39. PMID: 21291268; PMCID: PMC3631511.
      Citations: 47     Fields:    Translation:Cells
    27. Scharf L, Li NS, Hawk AJ, Zhang T, Fox LM, Kazen AR, Shah S, Haddadian EJ, Gumperz JE, Saghatelian A, Meredith SC, Piccirilli JA, Adams EJ, Garzón D, Faraldo-Gómez JD. The 2.5 Å structure of CD1c in complex with a mycobacterial lipid reveals an open groove ideally suited for diverse antigen presentation. Immunity. 2010 Dec 14; 33(6):853-62. PMID: 21167756; PMCID: PMC3010391.
      Citations: 65     Fields:    Translation:HumansCells
    28. Lanning JD, Hawk AJ, Derryberry J, Meredith SC. Chaperone-like N-methyl peptide inhibitors of polyglutamine aggregation. Biochemistry. 2010 Aug 24; 49(33):7108-18. PMID: 20583779; PMCID: PMC2965777.
      Citations: 8     Fields:    Translation:HumansCells
    29. Bockhorn JJ, Lazar KL, Gasser AJ, Luther LM, Qahwash IM, Chopra N, Meredith SC. Novel semisynthetic method for generating full length beta-amyloid peptides. Biopolymers. 2010; 94(4):511-20. PMID: 20593467; PMCID: PMC2965776.
      Citations: 2     Fields:    Translation:HumansCells
    30. Liebman SW, Meredith SC. Protein folding: sticky N17 speeds huntingtin pile-up. Nat Chem Biol. 2010 Jan; 6(1):7-8. PMID: 20016493.
      Citations: 13     Fields:    Translation:HumansCells
    31. Darnell GD, Derryberry J, Kurutz JW, Meredith SC. Mechanism of cis-inhibition of polyQ fibrillation by polyP: PPII oligomers and the hydrophobic effect. Biophys J. 2009 Oct 21; 97(8):2295-305. PMID: 19843462; PMCID: PMC2764074.
      Citations: 27     Fields:    Translation:HumansCells
    32. Tycko R, Sciarretta KL, Orgel JP, Meredith SC. Evidence for novel beta-sheet structures in Iowa mutant beta-amyloid fibrils. Biochemistry. 2009 Jul 07; 48(26):6072-84. PMID: 19358576; PMCID: PMC2910621.
      Citations: 61     Fields:    Translation:HumansCells
    33. Paravastu AK, Qahwash I, Leapman RD, Meredith SC, Tycko R. Seeded growth of beta-amyloid fibrils from Alzheimer's brain-derived fibrils produces a distinct fibril structure. Proc Natl Acad Sci U S A. 2009 May 05; 106(18):7443-8. PMID: 19376973; PMCID: PMC2678625.
      Citations: 149     Fields:    Translation:Humans
    34. Chopra N, Gan W, Schreiber H, Kurutz JW, Meredith SC. Versatile cyclic templates for assembly of axially oriented ligands. Bioconjug Chem. 2009 Feb; 20(2):231-40. PMID: 19159293.
      Citations: 1     Fields:    Translation:Cells
    35. Carnemolla R, Ren X, Biswas TK, Meredith SC, Reardon CA, Wang J, Getz GS. The specific amino acid sequence between helices 7 and 8 influences the binding specificity of human apolipoprotein A-I for high density lipoprotein (HDL) subclasses: a potential for HDL preferential generation. J Biol Chem. 2008 Jun 06; 283(23):15779-88. PMID: 18385132; PMCID: PMC2414305.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    36. Makabe K, Biancalana M, Yan S, Tereshko V, Gawlak G, Meredith SC, Koide S, Miller-Auer H. High-resolution structure of a self-assembly-competent form of a hydrophobic peptide captured in a soluble beta-sheet scaffold. J Mol Biol. 2008 Apr 25; 378(2):459-67. PMID: 18367205; PMCID: PMC2390815.
      Citations: 5     Fields:    Translation:Cells
    37. Darnell G, Orgel JP, Pahl R, Meredith SC. Flanking polyproline sequences inhibit beta-sheet structure in polyglutamine segments by inducing PPII-like helix structure. J Mol Biol. 2007 Nov 30; 374(3):688-704. PMID: 17945257.
      Citations: 84     Fields:    Translation:Cells
    38. Qahwash IM, Boire A, Lanning J, Krausz T, Pytel P, Meredith SC. Site-specific effects of peptide lipidation on beta-amyloid aggregation and cytotoxicity. J Biol Chem. 2007 Dec 21; 282(51):36987-97. PMID: 17693400.
      Citations: 8     Fields:    Translation:HumansCells
    39. Im H, Manolopoulou M, Malito E, Shen Y, Zhao J, Neant-Fery M, Sun CY, Meredith SC, Sisodia SS, Leissring MA, Tang WJ. Structure of substrate-free human insulin-degrading enzyme (IDE) and biophysical analysis of ATP-induced conformational switch of IDE. J Biol Chem. 2007 Aug 31; 282(35):25453-63. PMID: 17613531.
      Citations: 65     Fields:    Translation:HumansCells
    40. Lazar KL, Kurutz JW, Tycko R, Meredith SC. Encapsulation and NMR on an aggregating peptide before fibrillogenesis. J Am Chem Soc. 2006 Dec 27; 128(51):16460-1. PMID: 17177369.
      Citations:    Fields:    Translation:Cells
    41. Schietinger A, Philip M, Yoshida BA, Azadi P, Liu H, Meredith SC, Schreiber H. A mutant chaperone converts a wild-type protein into a tumor-specific antigen. Science. 2006 Oct 13; 314(5797):304-8. PMID: 17038624.
      Citations: 73     Fields:    Translation:AnimalsCells
    42. Sciarretta KL, Boire A, Gordon DJ, Meredith SC. Spatial separation of beta-sheet domains of beta-amyloid: disruption of each beta-sheet by N-methyl amino acids. Biochemistry. 2006 Aug 08; 45(31):9485-95. PMID: 16878983.
      Citations: 12     Fields:    Translation:HumansCells
    43. Sciarretta KL, Gordon DJ, Meredith SC. Peptide-based inhibitors of amyloid assembly. Methods Enzymol. 2006; 413:273-312. PMID: 17046402.
      Citations: 48     Fields:    Translation:Cells
    44. Meredith SC. Protein denaturation and aggregation: Cellular responses to denatured and aggregated proteins. Ann N Y Acad Sci. 2005 Dec; 1066:181-221. PMID: 16533927.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    45. Lazar KL, Getz GS, Orgel JP, Meredith SC, Miller-Auer H. Helix-turn-helix peptides that form alpha-helical fibrils: turn sequences drive fibril structure. Biochemistry. 2005 Sep 27; 44(38):12681-9. PMID: 16171382.
      Citations: 14     Fields:    Translation:Cells
    46. Sciarretta KL, Gordon DJ, Petkova AT, Tycko R, Meredith SC. Abeta40-Lactam(D23/K28) models a conformation highly favorable for nucleation of amyloid. Biochemistry. 2005 Apr 26; 44(16):6003-14. PMID: 15835889.
      Citations: 89     Fields:    Translation:HumansCells
    47. Schreiber K, Cannon RE, Karrison T, Beck-Engeser G, Huo D, Tennant RW, Jensen H, Kast WM, Krausz T, Meredith SC, Chen L, Schreiber H. Strong synergy between mutant ras and HPV16 E6/E7 in the development of primary tumors. Oncogene. 2004 May 13; 23(22):3972-9. PMID: 15077191.
      Citations: 18     Fields:    Translation:Animals
    48. Gordon DJ, Balbach JJ, Tycko R, Meredith SC. Increasing the amphiphilicity of an amyloidogenic peptide changes the beta-sheet structure in the fibrils from antiparallel to parallel. Biophys J. 2004 Jan; 86(1 Pt 1):428-34. PMID: 14695285; PMCID: PMC1303808.
      Citations: 30     Fields:    Translation:Cells
    49. Gordon DJ, Meredith SC. Probing the role of backbone hydrogen bonding in beta-amyloid fibrils with inhibitor peptides containing ester bonds at alternate positions. Biochemistry. 2003 Jan 21; 42(2):475-85. PMID: 12525175.
      Citations: 24     Fields:    Translation:HumansCells
    50. Spiotto MT, Yu P, Rowley DA, Nishimura MI, Meredith SC, Gajewski TF, Fu YX, Schreiber H. Increasing tumor antigen expression overcomes "ignorance" to solid tumors via crosspresentation by bone marrow-derived stromal cells. Immunity. 2002 Dec; 17(6):737-47. PMID: 12479820.
      Citations: 90     Fields:    Translation:AnimalsCells
    51. Balbach JJ, Petkova AT, Oyler NA, Antzutkin ON, Gordon DJ, Meredith SC, Tycko R. Supramolecular structure in full-length Alzheimer's beta-amyloid fibrils: evidence for a parallel beta-sheet organization from solid-state nuclear magnetic resonance. Biophys J. 2002 Aug; 83(2):1205-16. PMID: 12124300; PMCID: PMC1302222.
      Citations: 98     Fields:    Translation:HumansCells
    52. Gordon DJ, Tappe R, Meredith SC. Design and characterization of a membrane permeable N-methyl amino acid-containing peptide that inhibits Abeta1-40 fibrillogenesis. J Pept Res. 2002 Jul; 60(1):37-55. PMID: 12081625.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    53. Reschly EJ, Sorci-Thomas MG, Davidson WS, Meredith SC, Reardon CA, Getz GS. Apolipoprotein A-I alpha -helices 7 and 8 modulate high density lipoprotein subclass distribution. J Biol Chem. 2002 Mar 22; 277(12):9645-54. PMID: 11744719.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    54. Morgan DM, Lynn DG, Miller-Auer H, Meredith SC. A designed Zn2+-binding amphiphilic polypeptide: energetic consequences of pi-helicity. Biochemistry. 2001 Nov 20; 40(46):14020-9. PMID: 11705394.
      Citations: 2     Fields:    Translation:HumansCells
    55. Beck-Engeser GB, Monach PA, Mumberg D, Yang F, Wanderling S, Schreiber K, Espinosa R, Le Beau MM, Meredith SC, Schreiber H. Point mutation in essential genes with loss or mutation of the second allele: relevance to the retention of tumor-specific antigens. J Exp Med. 2001 Aug 06; 194(3):285-300. PMID: 11489948; PMCID: PMC2193475.
      Citations: 25     Fields:    Translation:AnimalsCells
    56. Gordon DJ, Sciarretta KL, Meredith SC. Inhibition of beta-amyloid(40) fibrillogenesis and disassembly of beta-amyloid(40) fibrils by short beta-amyloid congeners containing N-methyl amino acids at alternate residues. Biochemistry. 2001 Jul 27; 40(28):8237-45. PMID: 11444969.
      Citations: 60     Fields:    Translation:HumansCells
    57. Weijzen S, Meredith SC, Velders MP, Elmishad AG, Schreiber H, Kast WM. Pharmacokinetic differences between a T cell-tolerizing and a T cell-activating peptide. J Immunol. 2001 Jun 15; 166(12):7151-7. PMID: 11390461.
      Citations: 5     Fields:    Translation:AnimalsCells
    58. Siegel CT, Schreiber K, Meredith SC, Beck-Engeser GB, Lancki DW, Lazarski CA, Fu YX, Rowley DA, Schreiber H. Enhanced growth of primary tumors in cancer-prone mice after immunization against the mutant region of an inherited oncoprotein. J Exp Med. 2000 Jun 05; 191(11):1945-56. PMID: 10839809; PMCID: PMC2213520.
      Citations: 14     Fields:    Translation:AnimalsPHPublic Health
    59. Lynn DG, Meredith SC. Review: model peptides and the physicochemical approach to beta-amyloids. J Struct Biol. 2000 Jun; 130(2-3):153-73. PMID: 10940223.
      Citations: 22     Fields:    Translation:HumansCells
    60. Benzinger TL, Gregory DM, Burkoth TS, Miller-Auer H, Lynn DG, Botto RE, Meredith SC. Two-dimensional structure of beta-amyloid(10-35) fibrils. Biochemistry. 2000 Mar 28; 39(12):3491-9. PMID: 10727245.
      Citations: 54     Fields:    Translation:HumansCells
    61. Kim SH, Wang R, Gordon DJ, Bass J, Steiner DF, Thinakaran G, Lynn DG, Meredith SC, Sisodia SS. Familial British dementia: expression and metabolism of BRI. Ann N Y Acad Sci. 2000; 920:93-9. PMID: 11193182.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    62. Kim SH, Wang R, Gordon DJ, Bass J, Steiner DF, Lynn DG, Thinakaran G, Meredith SC, Sisodia SS. Furin mediates enhanced production of fibrillogenic ABri peptides in familial British dementia. Nat Neurosci. 1999 Nov; 2(11):984-8. PMID: 10526337.
      Citations: 47     Fields:    Translation:AnimalsCells
    63. Davis DP, Khurana R, Meredith S, Stevens FJ, Argon Y. Mapping the major interaction between binding protein and Ig light chains to sites within the variable domain. J Immunol. 1999 Oct 01; 163(7):3842-50. PMID: 10490983.
      Citations: 9     Fields:    Translation:AnimalsCells
    64. Dominguez SR, Miller-Auer H, Reardon CA, Meredith SC. Peptide model of a highly conserved, N-terminal domain of apolipoprotein E is able to modulate lipoprotein binding to a member of the class A scavenger receptor family. J Lipid Res. 1999 Apr; 40(4):753-63. PMID: 10191300.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    65. Gregory DM, Benzinger TL, Burkoth TS, Miller-Auer H, Lynn DG, Meredith SC, Botto RE. Dipolar recoupling NMR of biomolecular self-assemblies: determining inter- and intrastrand distances in fibrilized Alzheimer's beta-amyloid peptide. Solid State Nucl Magn Reson. 1998 Dec; 13(3):149-66. PMID: 10023844.
      Citations: 23     Fields:    Translation:Cells
    66. Benzinger TL, Gregory DM, Burkoth TS, Miller-Auer H, Lynn DG, Botto RE, Meredith SC. Propagating structure of Alzheimer's beta-amyloid(10-35) is parallel beta-sheet with residues in exact register. Proc Natl Acad Sci U S A. 1998 Nov 10; 95(23):13407-12. PMID: 9811813; PMCID: PMC24832.
      Citations: 141     Fields:    Translation:HumansCells
    67. Benzinger TL, Braddock DT, Dominguez SR, Burkoth TS, Miller-Auer H, Subramanian RM, Fless GM, Jones DN, Lynn DG, Meredith SC. Structure-function relationships in side chain lactam cross-linked peptide models of a conserved N-terminal domain of apolipoprotein E. Biochemistry. 1998 Sep 22; 37(38):13222-9. PMID: 9748329.
      Citations:    Fields:    Translation:AnimalsCells
    68. Dubey P, Meredith SC, Siegel CT, Schreiber H. Tumor cells induce cytolytic T cells to a single immunodominant mutant peptide. J Immunother. 1998 Jul; 21(4):277-82. PMID: 9672849.
      Citations:    Fields:    Translation:AnimalsCellsPHPublic Health
    69. Fless GM, Santiago JY, Furbee J, Meredith SC. Specificity of ligand-induced conformational change of lipoprotein(a). Biochemistry. 1997 Sep 23; 36(38):11304-13. PMID: 9298949.
      Citations:    Fields:    Translation:Cells
    70. Steck TL, Chiaraviglio L, Meredith S. Osmotic homeostasis in Dictyostelium discoideum: excretion of amino acids and ingested solutes. J Eukaryot Microbiol. 1997 Sep-Oct; 44(5):503-10. PMID: 9304820.
      Citations: 2     Fields:    Translation:AnimalsCells
    71. Shawver LK, Schwartz DP, Mann E, Chen H, Tsai J, Chu L, Taylorson L, Longhi M, Meredith S, Germain L, Jacobs JS, Tang C, Ullrich A, Berens ME, Hersh E, McMahon G, Hirth KP, Powell TJ. Inhibition of platelet-derived growth factor-mediated signal transduction and tumor growth by N-[4-(trifluoromethyl)-phenyl]5-methylisoxazole-4-carboxamide. Clin Cancer Res. 1997 Jul; 3(7):1167-77. PMID: 9815796.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    72. Dubey P, Hendrickson RC, Meredith SC, Siegel CT, Shabanowitz J, Skipper JC, Engelhard VH, Hunt DF, Schreiber H. The immunodominant antigen of an ultraviolet-induced regressor tumor is generated by a somatic point mutation in the DEAD box helicase p68. J Exp Med. 1997 Feb 17; 185(4):695-705. PMID: 9034148; PMCID: PMC2196148.
      Citations: 55     Fields:    Translation:AnimalsCells
    73. Braddock DT, Mercurius KO, Subramanian RM, Dominguez SR, Davies PF, Meredith SC. Conformationally specific enhancement of receptor-mediated LDL binding and internalization by peptide models of a conserved anionic N-terminal domain of human apolipoprotein E. Biochemistry. 1996 Nov 05; 35(44):13975-84. PMID: 8909295.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    74. Fless GM, Furbee J, Snyder ML, Meredith SC. Ligand-induced conformational change of lipoprotein(a). Biochemistry. 1996 Feb 20; 35(7):2289-98. PMID: 8652569.
      Citations: 2     Fields:    Translation:HumansCells
    75. Barbee KA, Morrow JA, Meredith SC. Deconvolution of gel filtration chromatographs of human plasma lipoproteins. Anal Biochem. 1995 Nov 01; 231(2):301-8. PMID: 8594977.
      Citations: 1     Fields:    Translation:Humans
    76. Monach PA, Meredith SC, Siegel CT, Schreiber H. A unique tumor antigen produced by a single amino acid substitution. Immunity. 1995 Jan; 2(1):45-59. PMID: 7600302.
      Citations: 101     Fields:    Translation:AnimalsCellsPHPublic Health
    77. Luo P, Braddock DT, Subramanian RM, Meredith SC, Lynn DG. Structural and thermodynamic characterization of a bioactive peptide model of apolipoprotein E: side-chain lactam bridges to constrain the conformation. Biochemistry. 1994 Oct 18; 33(41):12367-77. PMID: 7918459.
      Citations: 1     Fields:    Translation:Cells
    78. Teegarden D, Meredith SC, Sitrin MD. Determination of the affinity of vitamin D metabolites to serum vitamin D binding protein using assay employing lipid-coated polystyrene beads. Anal Biochem. 1991 Dec; 199(2):293-9. PMID: 1667458.
      Citations: 2     Fields:    Translation:AnimalsCells
    79. Kadowaki MH, Singh TM, Zarins CK, Glagov S, Meredith SC. The effect of hypercholesterolemia on early atherosclerotic lesions initiated by fibrinopeptide B. J Surg Res. 1991 Dec; 51(6):524-8. PMID: 1943091.
      Citations:    Fields:    Translation:Animals
    80. Tonsgard JH, Meredith SC. Characterization of the binding sites for dicarboxylic acids on bovine serum albumin. Biochem J. 1991 Jun 15; 276 ( Pt 3):569-75. PMID: 2064600; PMCID: PMC1151043.
      Citations: 3     Fields:    Translation:Cells
    81. Matsushima T, Getz GS, Meredith SC. Primary structure of guinea pig apolipoprotein E. Nucleic Acids Res. 1990 Jan 11; 18(1):202. PMID: 2308832; PMCID: PMC330239.
      Citations: 3     Fields:    Translation:AnimalsCells
    82. Tonsgard JH, Mendelson SA, Meredith SC. Binding of straight-chain saturated dicarboxylic acids to albumin. J Clin Invest. 1988 Nov; 82(5):1567-73. PMID: 3183053; PMCID: PMC442724.
      Citations: 3     Fields:    Translation:HumansCells
    83. Mora R, Berndt KD, Tsai H, Meredith SC. Quantitation of aspartate and glutamate in HPLC analysis of phenylthiocarbamyl amino acids. Anal Biochem. 1988 Aug 01; 172(2):368-76. PMID: 3189784.
      Citations: 2     Fields:    Translation:Cells
    84. Bolt MJ, Meredith SC, Rosenberg IH. Suppression of rat hepatic vitamin D-25-hydroxylase by cholecalciferol, but not by 25-hydroxy- or 1,25-dihydroxymetabolites. Calcif Tissue Int. 1988 Apr; 42(4):273-8. PMID: 2840181.
      Citations: 1     Fields:    Translation:Animals
    85. Gordon ED, Mora R, Meredith SC, Lee C, Lindquist SL. Eukaryotic initiation factor 4D, the hypusine-containing protein, is conserved among eukaryotes. J Biol Chem. 1987 Dec 05; 262(34):16585-9. PMID: 3119588.
      Citations: 26     Fields:    Translation:AnimalsCells
    86. Gordon ED, Mora R, Meredith SC, Lindquist SL. Hypusine formation in eukaryotic initiation factor 4D is not reversed when rates or specificity of protein synthesis is altered. J Biol Chem. 1987 Dec 05; 262(34):16590-5. PMID: 3119589.
      Citations: 5     Fields:    Translation:AnimalsCells
    87. Kawooya JK, Meredith SC, Wells MA, Law JH, Kézdy FJ. Physical and surface properties of insect apolipophorin III. J Biol Chem. 1986 Oct 15; 261(29):13588-91. PMID: 3759983.
      Citations: 8     Fields:    Translation:AnimalsCells
    88. Reddy MN, Maraganore JM, Meredith SC, Heinrikson RL, Kézdy FJ. Isolation of an active-site peptide of lipoprotein lipase from bovine milk and determination of its amino acid sequence. J Biol Chem. 1986 Jul 25; 261(21):9678-83. PMID: 3525532.
      Citations: 5     Fields:    Translation:AnimalsCells
    89. Borensztajn J, Kotlar TJ, Meredith SC. Fractionation of chylomicrons by heparin-sepharose chromatography. Characterization of two heparin-binding proteins. J Biol Chem. 1985 Oct 25; 260(24):13047-52. PMID: 3932338.
      Citations: 4     Fields:    Translation:Animals
    90. Retzinger GS, Meredith SC, Lau SH, Kaiser ET, Kézdy FJ. A method for probing the affinity of peptides for amphiphilic surfaces. Anal Biochem. 1985 Oct; 150(1):131-40. PMID: 4083474.
      Citations: 3     Fields:    Translation:Cells
    91. Meredith SC. The determination of molecular weight of proteins by gel permeation chromatography in organic solvents. J Biol Chem. 1984 Oct 10; 259(19):11682-5. PMID: 6480578.
      Citations: 4     Fields:    Translation:Cells
    92. Sellin JH, Meredith SC, Kelly S, Schneir H, Rosenberg IH. Prospective evaluation of metabolic bone disease after jejunoileal bypass. Gastroenterology. 1984 Jul; 87(1):123-9. PMID: 6724254.
      Citations: 5     Fields:    Translation:HumansCells
    93. Bengoa JM, Sitrin MD, Meredith S, Kelly SE, Shah N, Baker AL, Rosenberg IH. Intestinal calcium absorption and vitamin D status in chronic cholestatic liver disease. Hepatology. 1984 Mar-Apr; 4(2):261-5. PMID: 6706300.
      Citations: 12     Fields:    Translation:Humans
    94. Heinrikson RL, Meredith SC. Amino acid analysis by reverse-phase high-performance liquid chromatography: precolumn derivatization with phenylisothiocyanate. Anal Biochem. 1984 Jan; 136(1):65-74. PMID: 6711815.
      Citations: 262     Fields:    Translation:Animals
    95. Driscoll RH, Meredith SC, Sitrin M, Rosenberg IH. Vitamin D deficiency and bone disease in patients with Crohn's disease. Gastroenterology. 1982 Dec; 83(6):1252-8. PMID: 6982188.
      Citations: 48     Fields:    Translation:Humans
    96. Retzinger GS, Meredith SC, Hunter RL, Takayama K, Kézdy FJ. Identification of the physiologically active state of the mycobacterial glycolipid trehalose 6,6'-dimycolate and the role of fibrinogen in the biologic activities of trehalose 6,6'-dimycolate monolayers. J Immunol. 1982 Aug; 129(2):735-44. PMID: 6806381.
      Citations: 17     Fields:    Translation:AnimalsCells
    97. Meredith SC, Nathans GR. Gel permeation chromatography of asymmetric proteins. Anal Biochem. 1982 Apr; 121(2):234-43. PMID: 7103052.
      Citations:    Fields:    Translation:Animals
    98. Retzinger GS, Meredith SC, Takayama K, Hunter RL, Kézdy FJ. The role of surface in the biological activities of trehalose 6,6'-dimycolate. Surface properties and development of a model system. J Biol Chem. 1981 Aug 10; 256(15):8208-16. PMID: 7263645.
      Citations: 28     Fields:    Translation:HumansCells
    99. Schlenker JD, Indresano AT, Raine T, Meredith SC, Robson MC. A new flap in the dog containing a vascularized rib graft--the latissimus dorsi myoosteocutaneous flap. J Surg Res. 1980 Aug; 29(2):172-83. PMID: 7412260.
      Citations: 2     Fields:    Translation:Animals
    100. Sitrin MD, Rosenberg IH, Chawla K, Meredith S, Sellin J, Rabb JM, Coe F, Kirsner JB, Kraft SC. Nutritional and metabolic complications in a patient with Crohn's disease and ileal resection. Gastroenterology. 1980 May; 78(5 Pt 1):1069-79. PMID: 7380180.
      Citations: 3     Fields:    Translation:Humans
    101. Reed JS, Meredith SC, Nemchausky BA, Rosenberg IH, Boyer JL. Bone disease in primary biliary cirrhosis: reversal of osteomalacia with oral 25-hydroxyvitamin D. Gastroenterology. 1980 Mar; 78(3):512-7. PMID: 7351289.
      Citations: 14     Fields:    Translation:Humans
    102. Meredith SC, Rosenberg IH. Gastrointestinal-hepatic disorders and osteomalacia. Clin Endocrinol Metab. 1980 Mar; 9(1):131-50. PMID: 6998607.
      Citations: 2     Fields:    Translation:Humans
    103. Sitrin M, Meredith S, Rosenberg IH. Vitamin D deficiency and bone disease in gastrointestinal disorders. Arch Intern Med. 1978 May 15; 138 Spec No:886-8. PMID: 646580.
      Citations: 7     Fields:    Translation:Humans
    104. Berns MW, Rattner JB, Meredith S, Witter M. Current laser microirradiation studies. Ann N Y Acad Sci. 1976 Jan 30; 267:160-75. PMID: 1064352.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
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