"Chromosomes, Artificial" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
DNA constructs that are composed of, at least, elements such as a REPLICATION ORIGIN; TELOMERE; and CENTROMERE, that are required for successful replication, propagation to and maintenance in progeny cells. In addition, they are constructed to carry other sequences for analysis or gene transfer.
| Descriptor ID |
D022201
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| MeSH Number(s) |
A11.284.187.178 G05.360.162.178 G05.360.337.249
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Chromosomes, Artificial".
Below are MeSH descriptors whose meaning is more specific than "Chromosomes, Artificial".
This graph shows the total number of publications written about "Chromosomes, Artificial" by people in this website by year, and whether "Chromosomes, Artificial" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 1 | 0 | 1 |
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Below are the most recent publications written about "Chromosomes, Artificial" by people in Profiles.
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Sequences associated with centromere competency in the human genome. Mol Cell Biol. 2013 Feb; 33(4):763-72.
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Neocentromeres and human artificial chromosomes: an unnatural act. Proc Natl Acad Sci U S A. 2001 May 08; 98(10):5374-6.
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An efficient method for high-fidelity BAC/PAC retrofitting with a selectable marker for mammalian cell transfection. Genome Res. 2001 Jan; 11(1):137-42.