"Isochromosomes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Metacentric chromosomes produced during MEIOSIS or MITOSIS when the CENTROMERE splits transversely instead of longitudinally. The chromosomes produced by this abnormal division are one chromosome having the two long arms of the original chromosome, but no short arms, and the other chromosome consisting of the two short arms and no long arms. Each of these isochromosomes constitutes a simultaneous duplication and deletion.
| Descriptor ID |
D018404
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| MeSH Number(s) |
A11.284.187.570 C23.550.210.430 G05.360.162.570 G05.365.590.175.430
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Isochromosomes".
Below are MeSH descriptors whose meaning is more specific than "Isochromosomes".
This graph shows the total number of publications written about "Isochromosomes" by people in this website by year, and whether "Isochromosomes" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Isochromosomes" by people in Profiles.
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Myelodysplastic/myeloproliferative neoplasms-unclassifiable with isolated isochromosome 17q represents a distinct clinico-biologic subset: a multi-institutional collaborative study from the Bone Marrow Pathology Group. Mod Pathol. 2022 04; 35(4):470-479.
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Molecular characterization of isochromosomes of Xq. Ann Hum Genet. 1997 Nov; 61(Pt 6):485-90.
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Molecular definition of breakpoints associated with human Xq isochromosomes: implications for mechanisms of formation. Am J Hum Genet. 1996 Jan; 58(1):154-60.