Phosphatidylinositol 3-Kinases
"Phosphatidylinositol 3-Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Phosphotransferases that catalyzes the conversion of 1-phosphatidylinositol to 1-phosphatidylinositol 3-phosphate. Many members of this enzyme class are involved in RECEPTOR MEDIATED SIGNAL TRANSDUCTION and regulation of vesicular transport with the cell. Phosphatidylinositol 3-Kinases have been classified both according to their substrate specificity and their mode of action within the cell.
Descriptor ID |
D019869
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MeSH Number(s) |
D08.811.913.696.620.500
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Concept/Terms |
Phosphatidylinositol 3-Kinases- Phosphatidylinositol 3-Kinases
- Phosphatidylinositol 3 Kinases
- Phosphoinositide 3-Hydroxykinase
- PI 3-Kinase
- PtdIns 3-Kinases
- 3-Kinases, PtdIns
- PtdIns 3 Kinases
- PI-3K
- PI3 Kinases
- Kinases, PI3
- PI3-Kinase
- PtdIns 3-Kinase
- Phosphatidylinositol-3-OH Kinase
- PI-3 Kinase
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Below are MeSH descriptors whose meaning is more general than "Phosphatidylinositol 3-Kinases".
Below are MeSH descriptors whose meaning is more specific than "Phosphatidylinositol 3-Kinases".
This graph shows the total number of publications written about "Phosphatidylinositol 3-Kinases" by people in this website by year, and whether "Phosphatidylinositol 3-Kinases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1993 | 0 | 1 | 1 |
1995 | 0 | 2 | 2 |
1996 | 0 | 2 | 2 |
1997 | 0 | 5 | 5 |
1998 | 1 | 2 | 3 |
1999 | 1 | 3 | 4 |
2000 | 4 | 6 | 10 |
2001 | 4 | 6 | 10 |
2002 | 3 | 6 | 9 |
2003 | 8 | 5 | 13 |
2004 | 4 | 2 | 6 |
2005 | 7 | 2 | 9 |
2006 | 2 | 5 | 7 |
2007 | 0 | 5 | 5 |
2008 | 3 | 6 | 9 |
2009 | 4 | 7 | 11 |
2010 | 4 | 6 | 10 |
2011 | 2 | 6 | 8 |
2012 | 1 | 10 | 11 |
2013 | 1 | 9 | 10 |
2014 | 5 | 9 | 14 |
2015 | 5 | 5 | 10 |
2016 | 1 | 9 | 10 |
2017 | 1 | 3 | 4 |
2018 | 1 | 3 | 4 |
2019 | 2 | 3 | 5 |
2020 | 0 | 1 | 1 |
2021 | 2 | 3 | 5 |
2022 | 0 | 7 | 7 |
2023 | 1 | 3 | 4 |
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Below are the most recent publications written about "Phosphatidylinositol 3-Kinases" by people in Profiles.
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ASO Visual Abstract: PI3K Pathway Alterations in Peritoneal Metastases are Associated with Earlier Recurrence for Patients with Colorectal Cancer Undergoing Optimal Cytoreductive Surgery. Ann Surg Oncol. 2023 05; 30(5):3123-3124.
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Oncogenic RAS promotes leukemic transformation of CUX1-deficient cells. Oncogene. 2023 03; 42(12):881-893.
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Targeted Therapy for MPNs: Going Beyond JAK Inhibitors. Curr Hematol Malig Rep. 2023 Jun; 18(3):41-55.
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PI3K Pathway Alterations in Peritoneal Metastases are Associated with Earlier Recurrence in Patients with Colorectal Cancer Undergoing Optimal Cytoreductive Surgery. Ann Surg Oncol. 2023 May; 30(5):3114-3122.
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Transcriptional Dysregulation Underlies Both Monogenic Arrhythmia Syndrome and Common Modifiers of Cardiac Repolarization. Circulation. 2023 Mar 07; 147(10):824-840.
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Mullerian adenosarcoma: clinicopathologic and molecular characterization highlighting recurrent BAP1 loss and distinctive features of high-grade tumors. Mod Pathol. 2022 11; 35(11):1684-1694.
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Muscone suppresses myocardial ischemia damage by regulating PI3K/Akt signaling pathway. Biochim Biophys Acta Mol Basis Dis. 2022 12 01; 1868(12):166539.
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Phase I/II clinical trial of temsirolimus and lenalidomide in patients with relapsed and refractory lymphomas. Haematologica. 2022 07 01; 107(7):1608-1618.
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Profiling PI3K-AKT-MTOR variants in focal brain malformations reveals new insights for diagnostic care. Brain. 2022 04 29; 145(3):925-938.
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Intermittent glucocorticoid treatment enhances skeletal muscle performance through sexually dimorphic mechanisms. J Clin Invest. 2022 03 15; 132(6).