Phosphatidylinositol 3-Kinases
"Phosphatidylinositol 3-Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Phosphotransferases that catalyzes the conversion of 1-phosphatidylinositol to 1-phosphatidylinositol 3-phosphate. Many members of this enzyme class are involved in RECEPTOR MEDIATED SIGNAL TRANSDUCTION and regulation of vesicular transport with the cell. Phosphatidylinositol 3-Kinases have been classified both according to their substrate specificity and their mode of action within the cell.
| Descriptor ID |
D019869
|
| MeSH Number(s) |
D08.811.913.696.620.500
|
| Concept/Terms |
Phosphatidylinositol 3-Kinases- Phosphatidylinositol 3-Kinases
- Phosphatidylinositol 3 Kinases
- Phosphoinositide 3-Hydroxykinase
- PI 3-Kinase
- PtdIns 3-Kinases
- 3-Kinases, PtdIns
- PtdIns 3 Kinases
- PI-3K
- PI3 Kinases
- Kinases, PI3
- PI3-Kinase
- PtdIns 3-Kinase
- Phosphatidylinositol-3-OH Kinase
- PI-3 Kinase
|
Below are MeSH descriptors whose meaning is more general than "Phosphatidylinositol 3-Kinases".
Below are MeSH descriptors whose meaning is more specific than "Phosphatidylinositol 3-Kinases".
This graph shows the total number of publications written about "Phosphatidylinositol 3-Kinases" by people in this website by year, and whether "Phosphatidylinositol 3-Kinases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 0 | 1 | 1 |
| 1995 | 0 | 2 | 2 |
| 1996 | 0 | 2 | 2 |
| 1997 | 0 | 5 | 5 |
| 1998 | 1 | 2 | 3 |
| 1999 | 1 | 3 | 4 |
| 2000 | 4 | 6 | 10 |
| 2001 | 4 | 6 | 10 |
| 2002 | 3 | 6 | 9 |
| 2003 | 8 | 5 | 13 |
| 2004 | 4 | 2 | 6 |
| 2005 | 7 | 2 | 9 |
| 2006 | 2 | 5 | 7 |
| 2007 | 0 | 5 | 5 |
| 2008 | 3 | 6 | 9 |
| 2009 | 4 | 7 | 11 |
| 2010 | 4 | 6 | 10 |
| 2011 | 2 | 6 | 8 |
| 2012 | 1 | 10 | 11 |
| 2013 | 1 | 9 | 10 |
| 2014 | 5 | 9 | 14 |
| 2015 | 5 | 5 | 10 |
| 2016 | 1 | 9 | 10 |
| 2017 | 1 | 3 | 4 |
| 2018 | 1 | 3 | 4 |
| 2019 | 2 | 3 | 5 |
| 2020 | 0 | 1 | 1 |
| 2021 | 2 | 3 | 5 |
| 2022 | 0 | 7 | 7 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Phosphatidylinositol 3-Kinases" by people in Profiles.
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Oncogenic RAS promotes leukemic transformation of CUX1-deficient cells. Oncogene. 2023 Mar; 42(12):881-893.
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Transcriptional Dysregulation Underlies Both Monogenic Arrhythmia Syndrome and Common Modifiers of Cardiac Repolarization. Circulation. 2023 Mar 07; 147(10):824-840.
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Mullerian adenosarcoma: clinicopathologic and molecular characterization highlighting recurrent BAP1 loss and distinctive features of high-grade tumors. Mod Pathol. 2022 11; 35(11):1684-1694.
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Muscone suppresses myocardial ischemia damage by regulating PI3K/Akt signaling pathway. Biochim Biophys Acta Mol Basis Dis. 2022 12 01; 1868(12):166539.
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Phase I/II clinical trial of temsirolimus and lenalidomide in patients with relapsed and refractory lymphomas. Haematologica. 2022 07 01; 107(7):1608-1618.
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Profiling PI3K-AKT-MTOR variants in focal brain malformations reveals new insights for diagnostic care. Brain. 2022 04 29; 145(3):925-938.
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Intermittent glucocorticoid treatment enhances skeletal muscle performance through sexually dimorphic mechanisms. J Clin Invest. 2022 03 15; 132(6).
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A randomized phase II trial of everolimus and letrozole or hormonal therapy in women with advanced, persistent or recurrent endometrial carcinoma: A GOG Foundation study. Gynecol Oncol. 2022 03; 164(3):481-491.
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Disease- and Therapy-Specific Impact on Humoral Immune Responses to COVID-19 Vaccination in Hematologic Malignancies. Blood Cancer Discov. 2021 11; 2(6):568-576.
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Pan-PI3Ki targets multiple B-ALL microenvironment interactions that fuel systemic and CNS relapse. Leuk Lymphoma. 2021 11; 62(11):2690-2702.