"KCNQ1 Potassium Channel" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A voltage-gated potassium channel that is expressed primarily in the HEART.
| Descriptor ID |
D051657
|
| MeSH Number(s) |
D12.776.157.530.400.600.900.124.249.500 D12.776.543.550.450.750.900.124.249.500 D12.776.543.585.400.750.900.124.249.500
|
| Concept/Terms |
KCNQ1 Potassium Channel- KCNQ1 Potassium Channel
- Potassium Channel, KCNQ1
- Voltage-Gated K+ Channel KCNQ1
- Voltage Gated K+ Channel KCNQ1
- Kv7.1 Potassium Channel
- Potassium Channel, Kv7.1
- KVLQT1 Protein
- KCNQ1 Protein
|
Below are MeSH descriptors whose meaning is more general than "KCNQ1 Potassium Channel".
Below are MeSH descriptors whose meaning is more specific than "KCNQ1 Potassium Channel".
This graph shows the total number of publications written about "KCNQ1 Potassium Channel" by people in this website by year, and whether "KCNQ1 Potassium Channel" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 1 | 0 | 1 |
| 2008 | 2 | 0 | 2 |
| 2009 | 1 | 0 | 1 |
| 2010 | 3 | 1 | 4 |
| 2012 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
| 2023 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "KCNQ1 Potassium Channel" by people in Profiles.
-
Clinical and functional characterisation of a recurrent KCNQ1 variant in the Belgian population. Orphanet J Rare Dis. 2023 01 31; 18(1):23.
-
Molecular autopsy and subsequent functional analysis reveal de novo DSG2 mutation as cause of sudden death. Eur J Med Genet. 2021 Nov; 64(11):104322.
-
Transancestral fine-mapping of four type 2 diabetes susceptibility loci highlights potential causal regulatory mechanisms. Hum Mol Genet. 2016 05 15; 25(10):2070-2081.
-
Height-reducing variants and selection for short stature in Sardinia. Nat Genet. 2015 Nov; 47(11):1352-1356.
-
IKs channels open slowly because KCNE1 accessory subunits slow the movement of S4 voltage sensors in KCNQ1 pore-forming subunits. Proc Natl Acad Sci U S A. 2013 Feb 12; 110(7):E559-66.
-
Dual effect of phosphatidylinositol (4,5)-bisphosphate PIP(2) on Shaker K(+) [corrected] channels. J Biol Chem. 2012 Oct 19; 287(43):36158-67.
-
The S4-S5 linker of KCNQ1 channels forms a structural scaffold with the S6 segment controlling gate closure. J Biol Chem. 2011 Jan 07; 286(1):717-25.
-
KCNQ1 channels voltage dependence through a voltage-dependent binding of the S4-S5 linker to the pore domain. J Biol Chem. 2011 Jan 07; 286(1):707-16.
-
Phosphatidylinositol-4,5-bisphosphate (PIP(2)) stabilizes the open pore conformation of the Kv11.1 (hERG) channel. Biophys J. 2010 Aug 09; 99(4):1110-8.
-
A single nucleotide polymorphism in KCNQ1 is associated with susceptibility to diabetic nephropathy in japanese subjects with type 2 diabetes. Diabetes Care. 2010 Apr; 33(4):842-6.