G1 Phase Cell Cycle Checkpoints
"G1 Phase Cell Cycle Checkpoints" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Regulatory signaling systems that control the progression of the CELL CYCLE through the G1 PHASE and allow transition to S PHASE when the cells are ready to undergo DNA REPLICATION. DNA DAMAGE, or the deficiencies in specific cellular components or nutrients may cause the cells to halt before progressing through G1 phase.
| Descriptor ID |
D059585
|
| MeSH Number(s) |
G04.144.109.249 G04.144.500.320.500
|
| Concept/Terms |
G1 Phase Cell Cycle Checkpoints- G1 Phase Cell Cycle Checkpoints
- G1 Phase Checkpoints
- Checkpoint, G1 Phase
- Checkpoints, G1 Phase
- G1 Phase Checkpoint
- G1 Cell Cycle Checkpoints
G1 Phase Restriction Point- G1 Phase Restriction Point
- G1 Restriction Point
- G1 Restriction Points
- Restriction Point, G1
- Restriction Points, G1
|
Below are MeSH descriptors whose meaning is more general than "G1 Phase Cell Cycle Checkpoints".
Below are MeSH descriptors whose meaning is more specific than "G1 Phase Cell Cycle Checkpoints".
This graph shows the total number of publications written about "G1 Phase Cell Cycle Checkpoints" by people in this website by year, and whether "G1 Phase Cell Cycle Checkpoints" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "G1 Phase Cell Cycle Checkpoints" by people in Profiles.
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Ruthenium-dihydroartemisinin complex: a promising new compound for colon cancer prevention via G1 cell cycle arrest, apoptotic induction, and adaptive immune regulation. Cancer Chemother Pharmacol. 2024 May; 93(5):411-425.
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Fluorescein hydrazones: A series of novel non-intercalative topoisomerase IIa catalytic inhibitors induce G1 arrest and apoptosis in breast and colon cancer cells. Eur J Med Chem. 2017 Jan 05; 125:49-67.
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Met gene amplification and protein hyperactivation is a mechanism of resistance to both first and third generation EGFR inhibitors in lung cancer treatment. Cancer Lett. 2016 10 01; 380(2):494-504.
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Brucella abortus Cell Cycle and Infection Are Coordinated. Trends Microbiol. 2015 Dec; 23(12):812-821.
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DNA resection proteins Sgs1 and Exo1 are required for G1 checkpoint activation in budding yeast. DNA Repair (Amst). 2013 Sep; 12(9):751-60.
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The JmjC domain-containing histone demethylase KDM3A is a positive regulator of the G1/S transition in cancer cells via transcriptional regulation of the HOXA1 gene. Int J Cancer. 2012 Aug 01; 131(3):E179-89.