G2 Phase Cell Cycle Checkpoints
"G2 Phase Cell Cycle Checkpoints" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
CELL CYCLE regulatory signaling systems that are triggered by DNA DAMAGE or lack of nutrients during G2 PHASE. When triggered they restrain cells transitioning from G2 phase to M PHASE.
| Descriptor ID |
D059565
|
| MeSH Number(s) |
G04.144.109.500 G04.144.500.340.500
|
| Concept/Terms |
G2 Phase Cell Cycle Checkpoints- G2 Phase Cell Cycle Checkpoints
- G2 Phase Checkpoints
- Checkpoint, G2 Phase
- Checkpoints, G2 Phase
- G2 Phase Checkpoint
- G2 Cell Cycle Checkpoints
G2 Restriction Point- G2 Restriction Point
- G2 Restriction Points
- Restriction Point, G2
- Restriction Points, G2
Antephase Checkpoint- Antephase Checkpoint
- Antephase Checkpoints
- Checkpoint, Antephase
- Checkpoints, Antephase
|
Below are MeSH descriptors whose meaning is more general than "G2 Phase Cell Cycle Checkpoints".
Below are MeSH descriptors whose meaning is more specific than "G2 Phase Cell Cycle Checkpoints".
This graph shows the total number of publications written about "G2 Phase Cell Cycle Checkpoints" by people in this website by year, and whether "G2 Phase Cell Cycle Checkpoints" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 2 | 2 |
| 2015 | 2 | 0 | 2 |
| 2017 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "G2 Phase Cell Cycle Checkpoints" by people in Profiles.
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DNA Double-strand Break Signaling Is a Therapeutic Target in Head and Neck Cancer. Anticancer Res. 2021 Nov; 41(11):5393-5403.
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In vitro and in vivo efficacy of the novel oral proteasome inhibitor NNU546 in multiple myeloma. Aging (Albany NY). 2020 11 16; 12(22):22949-22974.
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Protein kinase D inhibitor CRT0066101 suppresses bladder cancer growth in vitro and xenografts via blockade of the cell cycle at G2/M. Cell Mol Life Sci. 2018 03; 75(5):939-963.
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PP2A inhibitors arrest G2/M transition through JNK/Sp1- dependent down-regulation of CDK1 and autophagy-dependent up-regulation of p21. Oncotarget. 2015 Jul 30; 6(21):18469-83.
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Anti-Colon Cancer Effects of 6-Shogaol Through G2/M Cell Cycle Arrest by p53/p21-cdc2/cdc25A Crosstalk. Am J Chin Med. 2015; 43(4):743-56.
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Genistein induces G2/M cell cycle arrest and apoptosis via ATM/p53-dependent pathway in human colon cancer cells. Int J Oncol. 2013 Jul; 43(1):289-96.
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Genistein sensitizes bladder cancer cells to HCPT treatment in vitro and in vivo via ATM/NF-?B/IKK pathway-induced apoptosis. PLoS One. 2013; 8(1):e50175.
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Hydrophobic flavonoids from Scutellaria baicalensis induce colorectal cancer cell apoptosis through a mitochondrial-mediated pathway. Int J Oncol. 2013 Mar; 42(3):1018-26.
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Exonuclease 1 (Exo1) is required for activating response to S(N)1 DNA methylating agents. DNA Repair (Amst). 2012 Dec 01; 11(12):951-64.