"Morpholinos" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Synthetic analogs of NUCLEIC ACIDS composed of morpholine ring derivatives (MORPHOLINES) linked by phosphorodimidates. One standard DNA nucleic acid base (ADENINE; GUANINE; CYTOSINE; OR THYMINE) is bound to each morpholine ring.
| Descriptor ID |
D060172
|
| MeSH Number(s) |
D03.383.533.640.562 D13.695.578.424.337
|
| Concept/Terms |
Morpholinos- Morpholinos
- Morpholino Oligonucleotides
- Oligonucleotides, Morpholino
- Phosphorodiamidate Morpholino Oligomers
- Morpholino Oligomers, Phosphorodiamidate
- Oligomers, Phosphorodiamidate Morpholino
- PMO Oligomers
- Oligomers, PMO
- Morpholino Oligos
- Oligos, Morpholino
- MORF Oligomers
- Oligomers, MORF
|
Below are MeSH descriptors whose meaning is more general than "Morpholinos".
Below are MeSH descriptors whose meaning is more specific than "Morpholinos".
This graph shows the total number of publications written about "Morpholinos" by people in this website by year, and whether "Morpholinos" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2015 | 0 | 2 | 2 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Morpholinos" by people in Profiles.
-
Mutations of the Transcriptional Corepressor ZMYM2 Cause Syndromic Urinary Tract Malformations. Am J Hum Genet. 2020 10 01; 107(4):727-742.
-
Efficient exon skipping of SGCG mutations mediated by phosphorodiamidate morpholino oligomers. JCI Insight. 2018 05 03; 3(9).
-
Mutation-Based Therapy for Duchenne Muscular Dystrophy: Antisense Treatment Arrives in the Clinic. Circulation. 2017 09 12; 136(11):979-981.
-
Polyamine biosynthesis is critical for growth and differentiation of the pancreas. Sci Rep. 2015 Aug 24; 5:13269.
-
Rest represses maturation within migrating facial branchiomotor neurons. Dev Biol. 2015 May 15; 401(2):220-35.
-
Axon tracts guide zebrafish facial branchiomotor neuron migration through the hindbrain. Development. 2013 Feb; 140(4):906-15.
-
Molecular target validation, antimicrobial delivery, and potential treatment of Toxoplasma gondii infections. Proc Natl Acad Sci U S A. 2012 Aug 28; 109(35):14182-7.
-
Functional roles of Notch signaling in the cnidarian Nematostella vectensis. Dev Biol. 2012 Feb 15; 362(2):295-308.
-
Down-regulation of SNAIL suppresses MIN mouse tumorigenesis: modulation of apoptosis, proliferation, and fractal dimension. Mol Cancer Ther. 2004 Sep; 3(9):1159-65.