"Peptide Nucleic Acids" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
DNA analogs containing neutral amide backbone linkages composed of aminoethyl glycine units instead of the usual phosphodiester linkage of deoxyribose groups. Peptide nucleic acids have high biological stability and higher affinity for complementary DNA or RNA sequences than analogous DNA oligomers.
| Descriptor ID |
D020135
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| MeSH Number(s) |
D13.695.578.424.550
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Peptide Nucleic Acids".
Below are MeSH descriptors whose meaning is more specific than "Peptide Nucleic Acids".
This graph shows the total number of publications written about "Peptide Nucleic Acids" by people in this website by year, and whether "Peptide Nucleic Acids" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 |
| 2008 | 2 | 0 | 2 |
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Below are the most recent publications written about "Peptide Nucleic Acids" by people in Profiles.
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The RNA2-PNA2 hybrid i-motif-a novel RNA-based building block. Chem Commun (Camb). 2008 Jan 07; (1):70-2.
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Combining G-quadruplex targeting motifs on a single peptide nucleic acid scaffold: a hybrid (3+1) PNA-DNA bimolecular quadruplex. Chemistry. 2008; 14(28):8682-9.
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The PNA-DNA hybrid I-motif: implications for sugar-sugar contacts in i-motif tetramerization. Nucleic Acids Res. 2006; 34(16):4354-63.