Chuan He to Adenosine
This is a "connection" page, showing publications Chuan He has written about Adenosine.
Connection Strength
25.279
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Small-molecule-catalysed deamination enables transcriptome-wide profiling of N6-methyladenosine in RNA. Nat Chem. 2025 Jul; 17(7):1042-1052.
Score: 0.727
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Acetylation of METTL3: A negative regulator of m6A deposition on chromatin-associated regulatory RNAs. Mol Cell. 2025 Apr 03; 85(7):1251-1252.
Score: 0.725
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N6-methyladenosine reader YTHDF2 in cell state transition and antitumor immunity. RNA. 2025 Feb 19; 31(3):395-401.
Score: 0.719
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Quantitative profiling of m6A at single base resolution across the life cycle of rice and Arabidopsis. Nat Commun. 2024 Jun 07; 15(1):4881.
Score: 0.685
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The YTHDF proteins display distinct cellular functions on m6A-modified RNA. Trends Biochem Sci. 2024 07; 49(7):611-621.
Score: 0.680
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FTO mediates LINE1 m6A demethylation and chromatin regulation in mESCs and mouse development. Science. 2022 05 27; 376(6596):968-973.
Score: 0.593
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Chromatin and transcriptional regulation by reversible RNA methylation. Curr Opin Cell Biol. 2021 06; 70:109-115.
Score: 0.547
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m6 A RNA methylation: from mechanisms to therapeutic potential. EMBO J. 2021 02 01; 40(3):e105977.
Score: 0.542
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LEAD-m6 A-seq for Locus-Specific Detection of N6 -Methyladenosine and Quantification of Differential Methylation. Angew Chem Int Ed Engl. 2021 01 11; 60(2):873-880.
Score: 0.535
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Genetic analyses support the contribution of mRNA N6-methyladenosine (m6A) modification to human disease heritability. Nat Genet. 2020 09; 52(9):939-949.
Score: 0.521
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YTHDF2 promotes mitotic entry and is regulated by cell cycle mediators. PLoS Biol. 2020 04; 18(4):e3000664.
Score: 0.513
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N6-methyladenosine of chromosome-associated regulatory RNA regulates chromatin state and transcription. Science. 2020 01 31; 367(6477):580-586.
Score: 0.505
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The RNA-binding protein FMRP facilitates the nuclear export of N6-methyladenosine-containing mRNAs. J Biol Chem. 2019 12 27; 294(52):19889-19895.
Score: 0.500
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Site-specific m6A editing. Nat Chem Biol. 2019 09; 15(9):848-849.
Score: 0.492
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Where, When, and How: Context-Dependent Functions of RNA Methylation Writers, Readers, and Erasers. Mol Cell. 2019 05 16; 74(4):640-650.
Score: 0.482
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Regulation of Gene Expression by N6-methyladenosine in Cancer. Trends Cell Biol. 2019 06; 29(6):487-499.
Score: 0.478
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Anti-tumour immunity controlled through mRNA m6A methylation and YTHDF1 in dendritic cells. Nature. 2019 02; 566(7743):270-274.
Score: 0.473
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High-Resolution Mapping of N 6-Methyladenosine Using m6A Crosslinking Immunoprecipitation Sequencing (m6A-CLIP-Seq). Methods Mol Biol. 2019; 1870:69-79.
Score: 0.470
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Differential m6A, m6Am, and m1A Demethylation Mediated by FTO in the Cell Nucleus and Cytoplasm. Mol Cell. 2018 09 20; 71(6):973-985.e5.
Score: 0.460
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m6A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer. Nat Cell Biol. 2018 09; 20(9):1074-1083.
Score: 0.459
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Phasing Gene Expression: mRNA N6-Methyladenosine Regulates Temporal Progression of Mammalian Cortical Neurogenesis. Biochemistry. 2018 02 20; 57(7):1055-1056.
Score: 0.441
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Identifying the m6A Methylome by Affinity Purification and Sequencing. Methods Mol Biol. 2018; 1649:49-57.
Score: 0.439
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Making Changes: N6-Methyladenosine-Mediated Decay Drives the Endothelial-to-Hematopoietic Transition. Biochemistry. 2017 11 21; 56(46):6077-6078.
Score: 0.434
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Epitranscriptomic influences on development and disease. Genome Biol. 2017 10 23; 18(1):197.
Score: 0.433
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YTHDC1 mediates nuclear export of N6-methyladenosine methylated mRNAs. Elife. 2017 10 06; 6.
Score: 0.432
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Ythdc2 is an N6-methyladenosine binding protein that regulates mammalian spermatogenesis. Cell Res. 2017 Sep; 27(9):1115-1127.
Score: 0.427
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m6A-dependent maternal mRNA clearance facilitates zebrafish maternal-to-zygotic transition. Nature. 2017 02 23; 542(7642):475-478.
Score: 0.413
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YTHDF3 facilitates translation and decay of N6-methyladenosine-modified RNA. Cell Res. 2017 Mar; 27(3):315-328.
Score: 0.411
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A glance at N(6)-methyladenosine in transcript isoforms. Nat Methods. 2016 07 28; 13(8):624-5.
Score: 0.397
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Nuclear m(6)A Reader YTHDC1 Regulates mRNA Splicing. Trends Genet. 2016 06; 32(6):320-321.
Score: 0.389
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High-Resolution Mapping of N6-Methyladenosine in Transcriptome and Genome Using a Photo-Crosslinking-Assisted Strategy. Methods Enzymol. 2015; 560:161-85.
Score: 0.370
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RNA N6-methyladenosine methylation in post-transcriptional gene expression regulation. Genes Dev. 2015 Jul 01; 29(13):1343-55.
Score: 0.369
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Widespread occurrence of N6-methyladenosine in bacterial mRNA. Nucleic Acids Res. 2015 Jul 27; 43(13):6557-67.
Score: 0.367
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N(6)-methyladenosine Modulates Messenger RNA Translation Efficiency. Cell. 2015 Jun 04; 161(6):1388-99.
Score: 0.367
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Preparation of Human Nuclear RNA m6A Methyltransferases and Demethylases and Biochemical Characterization of Their Catalytic Activity. Methods Enzymol. 2015; 560:117-30.
Score: 0.364
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Unique features of the m6A methylome in Arabidopsis thaliana. Nat Commun. 2014 Nov 28; 5:5630.
Score: 0.354
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Gene expression regulation mediated through reversible m6A RNA methylation. Nat Rev Genet. 2014 May; 15(5):293-306.
Score: 0.338
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A METTL3-METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation. Nat Chem Biol. 2014 Feb; 10(2):93-5.
Score: 0.331
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N6-methyladenosine-dependent regulation of messenger RNA stability. Nature. 2014 Jan 02; 505(7481):117-20.
Score: 0.330
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FTO-mediated formation of N6-hydroxymethyladenosine and N6-formyladenosine in mammalian RNA. Nat Commun. 2013; 4:1798.
Score: 0.310
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Reversible RNA adenosine methylation in biological regulation. Trends Genet. 2013 Feb; 29(2):108-15.
Score: 0.309
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N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO. Nat Chem Biol. 2011 Oct 16; 7(12):885-7.
Score: 0.285
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Structure determination of DNA methylation lesions N1-meA and N3-meC in duplex DNA using a cross-linked protein-DNA system. Nucleic Acids Res. 2010 Jul; 38(13):4415-25.
Score: 0.255
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RNA modification systems as therapeutic targets. Nat Rev Drug Discov. 2026 01; 25(1):59-78.
Score: 0.187
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FTO degrader impairs ribosome biogenesis and protein translation in acute myeloid leukemia. Sci Adv. 2025 Aug 15; 11(33):eadv7648.
Score: 0.186
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IGF2BP3 promotes mRNA degradation through internal m7G modification. Nat Commun. 2024 Aug 28; 15(1):7421.
Score: 0.174
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m6A RNA methylation regulates mitochondrial function. Hum Mol Genet. 2024 05 18; 33(11):969-980.
Score: 0.171
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Mammalian DNA N6-methyladenosine: Challenges and new insights. Mol Cell. 2023 02 02; 83(3):343-351.
Score: 0.156
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Exon architecture controls mRNA m6A suppression and gene expression. Science. 2023 02 17; 379(6633):677-682.
Score: 0.156
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Transcriptome-wide profiling and quantification of N6-methyladenosine by enzyme-assisted adenosine deamination. Nat Biotechnol. 2023 07; 41(7):993-1003.
Score: 0.155
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Detection of m6A RNA modifications at single-nucleotide resolution using m6A-selective allyl chemical labeling and sequencing. STAR Protoc. 2022 12 16; 3(4):101677.
Score: 0.152
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METTL16 exerts an m6A-independent function to facilitate translation and tumorigenesis. Nat Cell Biol. 2022 02; 24(2):205-216.
Score: 0.146
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Autophagy of the m6A mRNA demethylase FTO is impaired by low-level arsenic exposure to promote tumorigenesis. Nat Commun. 2021 04 12; 12(1):2183.
Score: 0.138
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N6 -methyladenosine modification of lncRNA Pvt1 governs epidermal stemness. EMBO J. 2021 04 15; 40(8):e106276.
Score: 0.137
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N6-Adenosine Methylation of Socs1 mRNA Is Required to Sustain the Negative Feedback Control of Macrophage Activation. Dev Cell. 2020 12 21; 55(6):737-753.e7.
Score: 0.134
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YTHDF3 Induces the Translation of m6A-Enriched Gene Transcripts to Promote Breast Cancer Brain Metastasis. Cancer Cell. 2020 12 14; 38(6):857-871.e7.
Score: 0.133
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A New Model of Spontaneous Colitis in Mice Induced by Deletion of an RNA m6A Methyltransferase Component METTL14 in T Cells. Cell Mol Gastroenterol Hepatol. 2020; 10(4):747-761.
Score: 0.130
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Control of Early B Cell Development by the RNA N6-Methyladenosine Methylation. Cell Rep. 2020 06 30; 31(13):107819.
Score: 0.130
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REPIC: a database for exploring the N6-methyladenosine methylome. Genome Biol. 2020 04 28; 21(1):100.
Score: 0.129
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m6A mRNA Methylation Is Essential for Oligodendrocyte Maturation and CNS Myelination. Neuron. 2020 01 22; 105(2):293-309.e5.
Score: 0.126
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Evolution of a reverse transcriptase to map N1-methyladenosine in human messenger RNA. Nat Methods. 2019 12; 16(12):1281-1288.
Score: 0.124
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Regulation of Co-transcriptional Pre-mRNA Splicing by m6A through the Low-Complexity Protein hnRNPG. Mol Cell. 2019 10 03; 76(1):70-81.e9.
Score: 0.123
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FMRP Modulates Neural Differentiation through m6A-Dependent mRNA Nuclear Export. Cell Rep. 2019 07 23; 28(4):845-854.e5.
Score: 0.122
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m6A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade. Nat Commun. 2019 06 25; 10(1):2782.
Score: 0.122
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Histone H3 trimethylation at lysine 36 guides m6A RNA modification co-transcriptionally. Nature. 2019 03; 567(7748):414-419.
Score: 0.119
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Transcriptome-wide reprogramming of N6-methyladenosine modification by the mouse microbiome. Cell Res. 2019 02; 29(2):167-170.
Score: 0.117
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N6-Methyladenosine methyltransferase ZCCHC4 mediates ribosomal RNA methylation. Nat Chem Biol. 2019 01; 15(1):88-94.
Score: 0.117
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Circadian Clock Regulation of Hepatic Lipid Metabolism by Modulation of m6A mRNA Methylation. Cell Rep. 2018 11 13; 25(7):1816-1828.e4.
Score: 0.116
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A dynamic N6-methyladenosine methylome regulates intrinsic and acquired resistance to tyrosine kinase inhibitors. Cell Res. 2018 11; 28(11):1062-1076.
Score: 0.116
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RNA modifications modulate gene expression during development. Science. 2018 09 28; 361(6409):1346-1349.
Score: 0.115
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Chemical Modifications in the Life of an mRNA Transcript. Annu Rev Genet. 2018 11 23; 52:349-372.
Score: 0.115
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Zc3h13 Regulates Nuclear RNA m6A Methylation and Mouse Embryonic Stem Cell Self-Renewal. Mol Cell. 2018 03 15; 69(6):1028-1038.e6.
Score: 0.111
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Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation. Nat Cell Biol. 2018 03; 20(3):285-295.
Score: 0.111
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METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m6A Modification. Cell Stem Cell. 2018 02 01; 22(2):191-205.e9.
Score: 0.110
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Our views of dynamic N6-methyladenosine RNA methylation. RNA. 2018 03; 24(3):268-272.
Score: 0.109
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ALKBH10B Is an RNA N6-Methyladenosine Demethylase Affecting Arabidopsis Floral Transition. Plant Cell. 2017 12; 29(12):2995-3011.
Score: 0.109
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m6A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells. Cell Rep. 2017 03 14; 18(11):2622-2634.
Score: 0.104
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Evolution of transcript modification by N6-methyladenosine in primates. Genome Res. 2017 03; 27(3):385-392.
Score: 0.102
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FTO Plays an Oncogenic Role in Acute Myeloid Leukemia as a N6-Methyladenosine RNA Demethylase. Cancer Cell. 2017 01 09; 31(1):127-141.
Score: 0.102
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Post-transcriptional gene regulation by mRNA modifications. Nat Rev Mol Cell Biol. 2017 01; 18(1):31-42.
Score: 0.101
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ALKBH1-Mediated tRNA Demethylation Regulates Translation. Cell. 2016 Oct 20; 167(3):816-828.e16.
Score: 0.101
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The dynamic N(1)-methyladenosine methylome in eukaryotic messenger RNA. Nature. 2016 Feb 25; 530(7591):441-6.
Score: 0.096
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Nucleic Acid Modifications in Regulation of Gene Expression. Cell Chem Biol. 2016 Jan 21; 23(1):74-85.
Score: 0.096
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N(6)-methyladenosine-dependent RNA structural switches regulate RNA-protein interactions. Nature. 2015 Feb 26; 518(7540):560-4.
Score: 0.090
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Nucleic acid modifications with epigenetic significance. Curr Opin Chem Biol. 2012 Dec; 16(5-6):516-24.
Score: 0.077
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YTHDFs as radiotherapy checkpoints in tumor immunity. J Exp Med. 2025 Aug 04; 222(8).
Score: 0.046
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Small-molecule inhibition of the METTL3/METTL14 complex suppresses neuroblastoma tumor growth and promotes differentiation. Cell Rep. 2024 05 28; 43(5):114165.
Score: 0.043
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A lncRNA from the FTO locus acts as a suppressor of the m6A writer complex and p53 tumor suppression signaling. Mol Cell. 2023 08 03; 83(15):2692-2708.e7.
Score: 0.040
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Globally reduced N6-methyladenosine (m6A) in C9ORF72-ALS/FTD dysregulates RNA metabolism and contributes to neurodegeneration. Nat Neurosci. 2023 08; 26(8):1328-1338.
Score: 0.040
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The METTL5-TRMT112 N6-methyladenosine methyltransferase complex regulates mRNA translation via 18S rRNA methylation. J Biol Chem. 2022 03; 298(3):101590.
Score: 0.036
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ALKBH7-mediated demethylation regulates mitochondrial polycistronic RNA processing. Nat Cell Biol. 2021 07; 23(7):684-691.
Score: 0.035
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YTHDF2 reduction fuels inflammation and vascular abnormalization in hepatocellular carcinoma. Mol Cancer. 2019 11 18; 18(1):163.
Score: 0.031
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R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m6A/MYC/CEBPA Signaling. Cell. 2018 01 11; 172(1-2):90-105.e23.
Score: 0.027
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Synthesis of a FTO inhibitor with anticonvulsant activity. ACS Chem Neurosci. 2014 Aug 20; 5(8):658-65.
Score: 0.021
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Genome-wide analysis of N1-methyl-adenosine modification in human tRNAs. RNA. 2010 Jul; 16(7):1317-27.
Score: 0.016