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Chuan He to Mice

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This is a "connection" page, showing publications Chuan He has written about Mice.
Chuan He
Connection Strength
2.876
Mice
  1. FTO degrader impairs ribosome biogenesis and protein translation in acute myeloid leukemia. Sci Adv. 2025 Aug 15; 11(33):eadv7648.
    View in: PubMed
    Score: 0.086
  2. snoRNA-facilitated protein secretion revealed by transcriptome-wide snoRNA target identification. Cell. 2025 Jan 23; 188(2):465-483.e22.
    View in: PubMed
    Score: 0.082
  3. RNA m5C oxidation by TET2 regulates chromatin state and leukaemogenesis. Nature. 2024 Oct; 634(8035):986-994.
    View in: PubMed
    Score: 0.081
  4. Quantitative analysis of cis-regulatory elements in transcription with KAS-ATAC-seq. Nat Commun. 2024 Aug 10; 15(1):6852.
    View in: PubMed
    Score: 0.080
  5. Sequencing of N6-methyl-deoxyadenosine at single-base resolution across the mammalian genome. Mol Cell. 2024 Feb 01; 84(3):596-610.e6.
    View in: PubMed
    Score: 0.077
  6. Ultrafast bisulfite sequencing detection of 5-methylcytosine in DNA and RNA. Nat Biotechnol. 2024 Oct; 42(10):1559-1570.
    View in: PubMed
    Score: 0.077
  7. BID-seq for transcriptome-wide quantitative sequencing of mRNA pseudouridine at base resolution. Nat Protoc. 2024 02; 19(2):517-538.
    View in: PubMed
    Score: 0.076
  8. YTHDF2/m6 A/NF-?B axis controls anti-tumor immunity by regulating intratumoral Tregs. EMBO J. 2023 08 01; 42(15):e113126.
    View in: PubMed
    Score: 0.074
  9. Quantitative sequencing using BID-seq uncovers abundant pseudouridines in mammalian mRNA at base resolution. Nat Biotechnol. 2023 03; 41(3):344-354.
    View in: PubMed
    Score: 0.071
  10. FTO mediates LINE1 m6A demethylation and chromatin regulation in mESCs and mouse development. Science. 2022 05 27; 376(6596):968-973.
    View in: PubMed
    Score: 0.069
  11. KAS-seq: genome-wide sequencing of single-stranded DNA by N3-kethoxal-assisted labeling. Nat Protoc. 2022 Feb; 17(2):402-420.
    View in: PubMed
    Score: 0.067
  12. Stabilization of ERK-Phosphorylated METTL3 by USP5 Increases m6A Methylation. Mol Cell. 2020 11 19; 80(4):633-647.e7.
    View in: PubMed
    Score: 0.062
  13. Direct DNA crosslinking with CAP-C uncovers transcription-dependent chromatin organization at high resolution. Nat Biotechnol. 2021 02; 39(2):225-235.
    View in: PubMed
    Score: 0.061
  14. A New Model of Spontaneous Colitis in Mice Induced by Deletion of an RNA m6A Methyltransferase Component METTL14 in T Cells. Cell Mol Gastroenterol Hepatol. 2020; 10(4):747-761.
    View in: PubMed
    Score: 0.060
  15. Kethoxal-assisted single-stranded DNA sequencing captures global transcription dynamics and enhancer activity in situ. Nat Methods. 2020 05; 17(5):515-523.
    View in: PubMed
    Score: 0.059
  16. DNA 5-Methylcytosine-Specific Amplification and Sequencing. J Am Chem Soc. 2020 03 11; 142(10):4539-4543.
    View in: PubMed
    Score: 0.059
  17. Keth-seq for transcriptome-wide RNA structure mapping. Nat Chem Biol. 2020 05; 16(5):489-492.
    View in: PubMed
    Score: 0.059
  18. N6-methyladenosine of chromosome-associated regulatory RNA regulates chromatin state and transcription. Science. 2020 01 31; 367(6477):580-586.
    View in: PubMed
    Score: 0.058
  19. The RNA-binding protein FMRP facilitates the nuclear export of N6-methyladenosine-containing mRNAs. J Biol Chem. 2019 12 27; 294(52):19889-19895.
    View in: PubMed
    Score: 0.058
  20. Transcriptome-wide Mapping of Internal N7-Methylguanosine Methylome in Mammalian mRNA. Mol Cell. 2019 06 20; 74(6):1304-1316.e8.
    View in: PubMed
    Score: 0.056
  21. Anti-tumour immunity controlled through mRNA m6A methylation and YTHDF1 in dendritic cells. Nature. 2019 02; 566(7743):270-274.
    View in: PubMed
    Score: 0.055
  22. RNA modifications modulate gene expression during development. Science. 2018 09 28; 361(6409):1346-1349.
    View in: PubMed
    Score: 0.053
  23. Differential m6A, m6Am, and m1A Demethylation Mediated by FTO in the Cell Nucleus and Cytoplasm. Mol Cell. 2018 09 20; 71(6):973-985.e5.
    View in: PubMed
    Score: 0.053
  24. Phasing Gene Expression: mRNA N6-Methyladenosine Regulates Temporal Progression of Mammalian Cortical Neurogenesis. Biochemistry. 2018 02 20; 57(7):1055-1056.
    View in: PubMed
    Score: 0.051
  25. Tet-Assisted Bisulfite Sequencing (TAB-seq). Methods Mol Biol. 2018; 1708:645-663.
    View in: PubMed
    Score: 0.051
  26. A Highly Sensitive and Robust Method for Genome-wide 5hmC Profiling of Rare Cell Populations. Mol Cell. 2016 08 18; 63(4):711-719.
    View in: PubMed
    Score: 0.046
  27. Inhibition of human copper trafficking by a small molecule significantly attenuates cancer cell proliferation. Nat Chem. 2015 Dec; 7(12):968-79.
    View in: PubMed
    Score: 0.044
  28. Genome-wide profiling of 5-formylcytosine reveals its roles in epigenetic priming. Cell. 2013 Apr 25; 153(3):678-91.
    View in: PubMed
    Score: 0.037
  29. Proteome-wide quantification and characterization of oxidation-sensitive cysteines in pathogenic bacteria. Cell Host Microbe. 2013 Mar 13; 13(3):358-70.
    View in: PubMed
    Score: 0.036
  30. Tet-mediated covalent labelling of 5-methylcytosine for its genome-wide detection and sequencing. Nat Commun. 2013; 4:1517.
    View in: PubMed
    Score: 0.036
  31. FTO-mediated formation of N6-hydroxymethyladenosine and N6-formyladenosine in mammalian RNA. Nat Commun. 2013; 4:1798.
    View in: PubMed
    Score: 0.036
  32. Tet-assisted bisulfite sequencing of 5-hydroxymethylcytosine. Nat Protoc. 2012 Dec; 7(12):2159-70.
    View in: PubMed
    Score: 0.036
  33. Protein cysteine phosphorylation of SarA/MgrA family transcriptional regulators mediates bacterial virulence and antibiotic resistance. Proc Natl Acad Sci U S A. 2012 Sep 18; 109(38):15461-6.
    View in: PubMed
    Score: 0.035
  34. Base-resolution analysis of 5-hydroxymethylcytosine in the mammalian genome. Cell. 2012 Jun 08; 149(6):1368-80.
    View in: PubMed
    Score: 0.034
  35. Targeting MgrA-mediated virulence regulation in Staphylococcus aureus. Chem Biol. 2011 Aug 26; 18(8):1032-41.
    View in: PubMed
    Score: 0.033
  36. Bioorthogonal labeling of 5-hydroxymethylcytosine in genomic DNA and diazirine-based DNA photo-cross-linking probes. Acc Chem Res. 2011 Sep 20; 44(9):709-17.
    View in: PubMed
    Score: 0.032
  37. Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine. Nat Biotechnol. 2011 Jan; 29(1):68-72.
    View in: PubMed
    Score: 0.031
  38. Golden pigment production and virulence gene expression are affected by metabolisms in Staphylococcus aureus. J Bacteriol. 2010 Jun; 192(12):3068-77.
    View in: PubMed
    Score: 0.030
  39. Pseudomonas aeruginosa OspR is an oxidative stress sensing regulator that affects pigment production, antibiotic resistance and dissemination during infection. Mol Microbiol. 2010 Jan; 75(1):76-91.
    View in: PubMed
    Score: 0.029
  40. A new oxidative sensing and regulation pathway mediated by the MgrA homologue SarZ in Staphylococcus aureus. Mol Microbiol. 2009 Jan; 71(1):198-211.
    View in: PubMed
    Score: 0.027
  41. Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO. FEBS Lett. 2008 Oct 15; 582(23-24):3313-9.
    View in: PubMed
    Score: 0.027
  42. Oxidative dealkylation DNA repair mediated by the mononuclear non-heme iron AlkB proteins. J Inorg Biochem. 2006 Apr; 100(4):670-8.
    View in: PubMed
    Score: 0.022
  43. Radiation-induced amphiregulin drives tumour metastasis. Nature. 2025 Jul; 643(8072):810-819.
    View in: PubMed
    Score: 0.021
  44. Targeting DTX2/UFD1-mediated FTO degradation to regulate antitumor immunity. Proc Natl Acad Sci U S A. 2024 Dec 17; 121(51):e2407910121.
    View in: PubMed
    Score: 0.021
  45. YTHDF1 loss in dendritic cells potentiates radiation-induced antitumor immunity via STING-dependent type I IFN production. J Clin Invest. 2024 Dec 02; 134(23).
    View in: PubMed
    Score: 0.020
  46. Targeting the Dendritic Cell-Secreted Immunoregulatory Cytokine CCL22 Alleviates Radioresistance. Clin Cancer Res. 2024 Oct 01; 30(19):4450-4463.
    View in: PubMed
    Score: 0.020
  47. m6A RNA methylation regulates mitochondrial function. Hum Mol Genet. 2024 05 18; 33(11):969-980.
    View in: PubMed
    Score: 0.020
  48. Small-molecule inhibition of the METTL3/METTL14 complex suppresses neuroblastoma tumor growth and promotes differentiation. Cell Rep. 2024 05 28; 43(5):114165.
    View in: PubMed
    Score: 0.020
  49. Trans-vaccenic acid reprograms CD8+ T cells and anti-tumour immunity. Nature. 2023 11; 623(7989):1034-1043.
    View in: PubMed
    Score: 0.019
  50. METTL14 is a chromatin regulator independent of its RNA N6-methyladenosine methyltransferase activity. Protein Cell. 2023 09 14; 14(9):683-697.
    View in: PubMed
    Score: 0.019
  51. A lncRNA from the FTO locus acts as a suppressor of the m6A writer complex and p53 tumor suppression signaling. Mol Cell. 2023 08 03; 83(15):2692-2708.e7.
    View in: PubMed
    Score: 0.019
  52. YTHDF2 inhibition potentiates radiotherapy antitumor efficacy. Cancer Cell. 2023 07 10; 41(7):1294-1308.e8.
    View in: PubMed
    Score: 0.018
  53. Transcriptome-wide profiling and quantification of N6-methyladenosine by enzyme-assisted adenosine deamination. Nat Biotechnol. 2023 07; 41(7):993-1003.
    View in: PubMed
    Score: 0.018
  54. N6-adenomethylation of GsdmC is essential for Lgr5+ stem cell survival to maintain normal colonic epithelial morphogenesis. Dev Cell. 2022 08 22; 57(16):1976-1994.e8.
    View in: PubMed
    Score: 0.017
  55. METTL16 exerts an m6A-independent function to facilitate translation and tumorigenesis. Nat Cell Biol. 2022 02; 24(2):205-216.
    View in: PubMed
    Score: 0.017
  56. The METTL5-TRMT112 N6-methyladenosine methyltransferase complex regulates mRNA translation via 18S rRNA methylation. J Biol Chem. 2022 03; 298(3):101590.
    View in: PubMed
    Score: 0.017
  57. HRD1-mediated METTL14 degradation regulates m6A mRNA modification to suppress ER proteotoxic liver disease. Mol Cell. 2021 12 16; 81(24):5052-5065.e6.
    View in: PubMed
    Score: 0.017
  58. METTL14 facilitates global genome repair and suppresses skin tumorigenesis. Proc Natl Acad Sci U S A. 2021 08 31; 118(35).
    View in: PubMed
    Score: 0.016
  59. Autophagy of the m6A mRNA demethylase FTO is impaired by low-level arsenic exposure to promote tumorigenesis. Nat Commun. 2021 04 12; 12(1):2183.
    View in: PubMed
    Score: 0.016
  60. N6 -methyladenosine modification of lncRNA Pvt1 governs epidermal stemness. EMBO J. 2021 04 15; 40(8):e106276.
    View in: PubMed
    Score: 0.016
  61. EGFR/SRC/ERK-stabilized YTHDF2 promotes cholesterol dysregulation and invasive growth of glioblastoma. Nat Commun. 2021 01 08; 12(1):177.
    View in: PubMed
    Score: 0.016
  62. N6-Adenosine Methylation of Socs1 mRNA Is Required to Sustain the Negative Feedback Control of Macrophage Activation. Dev Cell. 2020 12 21; 55(6):737-753.e7.
    View in: PubMed
    Score: 0.015
  63. YTHDF3 Induces the Translation of m6A-Enriched Gene Transcripts to Promote Breast Cancer Brain Metastasis. Cancer Cell. 2020 12 14; 38(6):857-871.e7.
    View in: PubMed
    Score: 0.015
  64. Upregulation of METTL14 mediates the elevation of PERP mRNA N6 adenosine methylation promoting the growth and metastasis of pancreatic cancer. Mol Cancer. 2020 08 25; 19(1):130.
    View in: PubMed
    Score: 0.015
  65. REPIC: a database for exploring the N6-methyladenosine methylome. Genome Biol. 2020 04 28; 21(1):100.
    View in: PubMed
    Score: 0.015
  66. m6A mRNA Methylation Is Essential for Oligodendrocyte Maturation and CNS Myelination. Neuron. 2020 01 22; 105(2):293-309.e5.
    View in: PubMed
    Score: 0.015
  67. YTHDF2 reduction fuels inflammation and vascular abnormalization in hepatocellular carcinoma. Mol Cancer. 2019 11 18; 18(1):163.
    View in: PubMed
    Score: 0.014
  68. m6A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade. Nat Commun. 2019 06 25; 10(1):2782.
    View in: PubMed
    Score: 0.014
  69. METTL14 is essential for ß-cell survival and insulin secretion. Biochim Biophys Acta Mol Basis Dis. 2019 09 01; 1865(9):2138-2148.
    View in: PubMed
    Score: 0.014
  70. Histone H3 trimethylation at lysine 36 guides m6A RNA modification co-transcriptionally. Nature. 2019 03; 567(7748):414-419.
    View in: PubMed
    Score: 0.014
  71. Inhibition of Copper Transport Induces Apoptosis in Triple-Negative Breast Cancer Cells and Suppresses Tumor Angiogenesis. Mol Cancer Ther. 2019 05; 18(5):873-885.
    View in: PubMed
    Score: 0.014
  72. Transcriptome-wide reprogramming of N6-methyladenosine modification by the mouse microbiome. Cell Res. 2019 02; 29(2):167-170.
    View in: PubMed
    Score: 0.014
  73. m6A facilitates hippocampus-dependent learning and memory through YTHDF1. Nature. 2018 11; 563(7730):249-253.
    View in: PubMed
    Score: 0.013
  74. A dynamic N6-methyladenosine methylome regulates intrinsic and acquired resistance to tyrosine kinase inhibitors. Cell Res. 2018 11; 28(11):1062-1076.
    View in: PubMed
    Score: 0.013
  75. Mettl14 Is Essential for Epitranscriptomic Regulation of Striatal Function and Learning. Neuron. 2018 07 25; 99(2):283-292.e5.
    View in: PubMed
    Score: 0.013
  76. Zc3h13 Regulates Nuclear RNA m6A Methylation and Mouse Embryonic Stem Cell Self-Renewal. Mol Cell. 2018 03 15; 69(6):1028-1038.e6.
    View in: PubMed
    Score: 0.013
  77. R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m6A/MYC/CEBPA Signaling. Cell. 2018 01 11; 172(1-2):90-105.e23.
    View in: PubMed
    Score: 0.013
  78. m6A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells. Cell Rep. 2017 03 14; 18(11):2622-2634.
    View in: PubMed
    Score: 0.012
  79. The dynamic N(1)-methyladenosine methylome in eukaryotic messenger RNA. Nature. 2016 Feb 25; 530(7591):441-6.
    View in: PubMed
    Score: 0.011
  80. Base-resolution detection of N4-methylcytosine in genomic DNA using 4mC-Tet-assisted-bisulfite- sequencing. Nucleic Acids Res. 2015 Dec 02; 43(21):e148.
    View in: PubMed
    Score: 0.011
  81. Base-resolution maps of 5-formylcytosine and 5-carboxylcytosine reveal genome-wide DNA demethylation dynamics. Cell Res. 2015 Mar; 25(3):386-9.
    View in: PubMed
    Score: 0.010
  82. 5mC oxidation by Tet2 modulates enhancer activity and timing of transcriptome reprogramming during differentiation. Mol Cell. 2014 Oct 23; 56(2):286-297.
    View in: PubMed
    Score: 0.010
  83. Blood-brain barrier permeable gold nanoparticles: an efficient delivery platform for enhanced malignant glioma therapy and imaging. Small. 2014 Dec 29; 10(24):5137-50.
    View in: PubMed
    Score: 0.010
  84. Synthesis of a FTO inhibitor with anticonvulsant activity. ACS Chem Neurosci. 2014 Aug 20; 5(8):658-65.
    View in: PubMed
    Score: 0.010
  85. HMGA2/TET1/HOXA9 signaling pathway regulates breast cancer growth and metastasis. Proc Natl Acad Sci U S A. 2013 Jun 11; 110(24):9920-5.
    View in: PubMed
    Score: 0.009
  86. ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility. Mol Cell. 2013 Jan 10; 49(1):18-29.
    View in: PubMed
    Score: 0.009
  87. Blockade of miR-150 maturation by MLL-fusion/MYC/LIN-28 is required for MLL-associated leukemia. Cancer Cell. 2012 Oct 16; 22(4):524-35.
    View in: PubMed
    Score: 0.009
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The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.