"Ubiquitin-Activating Enzymes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of enzymes that catalyzes the ATP-dependent formation of a thioester bond between itself and UBIQUITIN. It then transfers the activated ubiquitin to one of the UBIQUITIN-PROTEIN LIGASES.
- Ubiquitin-Activating Enzymes
- Enzymes, Ubiquitin-Activating
- Ubiquitin Activating Enzymes
- Ubiquitination Activating Enzyme E1
- Ubiquitin-Activating Enzyme
- Enzyme, Ubiquitin-Activating
- Ubiquitin Activating Enzyme
- Ubiquitin-Activating Enzyme E1
- Enzyme E1, Ubiquitin-Activating
- Ubiquitin Activating Enzyme E1
Below are MeSH descriptors whose meaning is more general than "Ubiquitin-Activating Enzymes".
Below are MeSH descriptors whose meaning is more specific than "Ubiquitin-Activating Enzymes".
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Below are the most recent publications written about "Ubiquitin-Activating Enzymes" by people in Profiles.
p62/SQSTM1 accumulation in squamous cell carcinoma of head and neck predicts sensitivity to phosphatidylinositol 3-kinase pathway inhibitors. PLoS One. 2014; 9(3):e90171.
Autophagy is a critical mechanism for the induction of the antileukemic effects of arsenic trioxide. J Biol Chem. 2010 Sep 24; 285(39):29989-97.
RasGRP1 stimulation enhances ubiquitination and endocytosis of the sodium-chloride cotransporter. Am J Physiol Renal Physiol. 2010 Aug; 299(2):F300-9.
Mechanistic insight into the allosteric activation of a ubiquitin-conjugating enzyme by RING-type ubiquitin ligases. Proc Natl Acad Sci U S A. 2005 Dec 27; 102(52):18890-5.
X inactivation analysis and DNA methylation studies of the ubiquitin activating enzyme E1 and PCTAIRE-1 genes in human and mouse. Hum Mol Genet. 1996 Mar; 5(3):391-401.