"Toll-Like Receptors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of pattern recognition receptors characterized by an extracellular leucine-rich domain and a cytoplasmic domain that share homology with the INTERLEUKIN 1 RECEPTOR and the DROSOPHILA toll protein. Following pathogen recognition, toll-like receptors recruit and activate a variety of SIGNAL TRANSDUCING ADAPTOR PROTEINS.
| Descriptor ID |
D051193
|
| MeSH Number(s) |
D12.776.543.750.705.910.500
|
| Concept/Terms |
Toll-Like Receptors- Toll-Like Receptors
- Toll Like Receptors
- Toll-Like Receptor
- Receptor, Toll-Like
- Toll Like Receptor
- Receptors, Toll-Like
- Receptors, Toll Like
|
Below are MeSH descriptors whose meaning is more general than "Toll-Like Receptors".
Below are MeSH descriptors whose meaning is more specific than "Toll-Like Receptors".
This graph shows the total number of publications written about "Toll-Like Receptors" by people in this website by year, and whether "Toll-Like Receptors" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 4 | 4 |
| 2004 | 0 | 3 | 3 |
| 2005 | 0 | 1 | 1 |
| 2006 | 2 | 3 | 5 |
| 2007 | 1 | 1 | 2 |
| 2008 | 2 | 2 | 4 |
| 2009 | 3 | 5 | 8 |
| 2010 | 1 | 1 | 2 |
| 2011 | 3 | 2 | 5 |
| 2012 | 2 | 0 | 2 |
| 2013 | 4 | 3 | 7 |
| 2014 | 1 | 1 | 2 |
| 2015 | 2 | 1 | 3 |
| 2016 | 1 | 0 | 1 |
| 2017 | 2 | 3 | 5 |
| 2018 | 1 | 1 | 2 |
| 2019 | 1 | 1 | 2 |
| 2020 | 1 | 1 | 2 |
| 2021 | 2 | 0 | 2 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Toll-Like Receptors" by people in Profiles.
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Methods to Study TLRs in Transplantation. Methods Mol Biol. 2023; 2700:139-149.
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Subunit Vaccines Using TLR Triagonist Combination Adjuvants Provide Protection Against Coxiella burnetii While Minimizing Reactogenic Responses. Front Immunol. 2021; 12:653092.
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Receptor-Ligand Kinetics Influence the Mechanism of Action of Covalently Linked TLR Ligands. ACS Chem Biol. 2021 02 19; 16(2):380-388.
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Distinct and Orchestrated Functions of RNA Sensors in Innate Immunity. Immunity. 2020 07 14; 53(1):26-42.
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Determining Whether Agonist Density or Agonist Number Is More Important for Immune Activation via Micoparticle Based Assay. Front Immunol. 2020; 11:642.
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Symptomatic Brain Hemorrhages from Cavernous Angioma After Botulinum Toxin Injections, a Role of TLR/MEKK3 Mechanism? Case Report and Review of the Literature. World Neurosurg. 2020 Apr; 136:7-11.
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Tuning Subunit Vaccines with Novel TLR Triagonist Adjuvants to Generate Protective Immune Responses against Coxiella burnetii. J Immunol. 2020 02 01; 204(3):611-621.
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Toll-like receptor signalling cross-activates the autophagic pathway to restrict Salmonella Typhimurium growth in macrophages. Cell Microbiol. 2019 12; 21(12):e13095.
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Metabolic and Innate Immune Cues Merge into a Specific Inflammatory Response via the UPR. Cell. 2019 05 16; 177(5):1201-1216.e19.
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Toll-like Receptor Agonist Conjugation: A Chemical Perspective. Bioconjug Chem. 2018 03 21; 29(3):587-603.