"Drug Discovery" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process of finding chemicals for potential therapeutic use.
| Descriptor ID |
D055808
|
| MeSH Number(s) |
E05.295 H01.158.703.007.675 H01.181.466.675
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Drug Discovery".
Below are MeSH descriptors whose meaning is more specific than "Drug Discovery".
This graph shows the total number of publications written about "Drug Discovery" by people in this website by year, and whether "Drug Discovery" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 1 | 2 |
| 2009 | 2 | 4 | 6 |
| 2010 | 4 | 2 | 6 |
| 2011 | 5 | 2 | 7 |
| 2012 | 5 | 0 | 5 |
| 2013 | 5 | 2 | 7 |
| 2014 | 3 | 1 | 4 |
| 2015 | 3 | 11 | 14 |
| 2016 | 6 | 0 | 6 |
| 2017 | 3 | 3 | 6 |
| 2018 | 3 | 2 | 5 |
| 2019 | 2 | 2 | 4 |
| 2020 | 3 | 0 | 3 |
| 2021 | 2 | 2 | 4 |
| 2022 | 2 | 1 | 3 |
To return to the timeline,
click here.
Below are the most recent publications written about "Drug Discovery" by people in Profiles.
-
Reliable and Accurate Prediction of Single-Residue pKa Values through Free Energy Perturbation Calculations. J Chem Theory Comput. 2022 Dec 13; 18(12):7193-7204.
-
OrganoID: A versatile deep learning platform for tracking and analysis of single-organoid dynamics. PLoS Comput Biol. 2022 11; 18(11):e1010584.
-
Hallmarks of aging-based dual-purpose disease and age-associated targets predicted using PandaOmics AI-powered discovery engine. Aging (Albany NY). 2022 03 29; 14(6):2475-2506.
-
Targeting the cytoskeleton and extracellular matrix in cardiovascular disease drug discovery. Expert Opin Drug Discov. 2022 05; 17(5):443-460.
-
Lentiviral-Driven Discovery of Cancer Drug Resistance Mutations. Cancer Res. 2021 09 15; 81(18):4685-4695.
-
Functional genomics for breast cancer drug target discovery. J Hum Genet. 2021 Sep; 66(9):927-935.
-
Discovery of SARS-CoV-2 main protease inhibitors using a synthesis-directed de novo design model. Chem Commun (Camb). 2021 Jun 15; 57(48):5909-5912.
-
Accelerating functional gene discovery in osteoarthritis. Nat Commun. 2021 01 20; 12(1):467.
-
Advancing Free-Energy Calculations of Metalloenzymes in Drug Discovery via Implementation of LFMM Potentials. J Chem Theory Comput. 2020 Nov 10; 16(11):6926-6937.
-
Protein targeting with SAF(er) electrophiles. Nat Chem. 2020 10; 12(10):885-887.