"Clinical Trials as Topic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Works about pre-planned studies of the safety, efficacy, or optimum dosage schedule (if appropriate) of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. This concept includes clinical trials conducted both in the U.S. and in other countries.
| Descriptor ID |
D002986
|
| MeSH Number(s) |
E05.318.760.250.500 N05.715.360.775.088.500 N06.850.520.450.250.250
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Clinical Trials as Topic".
Below are MeSH descriptors whose meaning is more specific than "Clinical Trials as Topic".
This graph shows the total number of publications written about "Clinical Trials as Topic" by people in this website by year, and whether "Clinical Trials as Topic" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 4 | 9 | 13 |
| 1996 | 2 | 9 | 11 |
| 1997 | 1 | 13 | 14 |
| 1998 | 0 | 4 | 4 |
| 1999 | 4 | 6 | 10 |
| 2000 | 3 | 17 | 20 |
| 2001 | 6 | 12 | 18 |
| 2002 | 3 | 20 | 23 |
| 2003 | 7 | 18 | 25 |
| 2004 | 10 | 38 | 48 |
| 2005 | 6 | 25 | 31 |
| 2006 | 12 | 41 | 53 |
| 2007 | 6 | 28 | 34 |
| 2008 | 9 | 32 | 41 |
| 2009 | 11 | 40 | 51 |
| 2010 | 9 | 28 | 37 |
| 2011 | 17 | 27 | 44 |
| 2012 | 17 | 27 | 44 |
| 2013 | 14 | 22 | 36 |
| 2014 | 8 | 21 | 29 |
| 2015 | 11 | 25 | 36 |
| 2016 | 10 | 27 | 37 |
| 2017 | 15 | 15 | 30 |
| 2018 | 8 | 34 | 42 |
| 2019 | 18 | 14 | 32 |
| 2020 | 12 | 25 | 37 |
| 2021 | 13 | 13 | 26 |
| 2022 | 3 | 10 | 13 |
| 2023 | 2 | 9 | 11 |
| 2024 | 12 | 11 | 23 |
| 2025 | 5 | 1 | 6 |
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click here.
Below are the most recent publications written about "Clinical Trials as Topic" by people in Profiles.
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Defining the role of pragmatic clinical trials in cancer clinical research: outcomes of a collaborative workshop hosted by the European Organisation for Research and Treatment of Cancer. Lancet Oncol. 2025 May; 26(5):e253-e263.
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Prevention and interception trials in inflammatory bowel disease: an international taskforce assessment on clinical trial design. Lancet Gastroenterol Hepatol. 2025 Jun; 10(6):593-604.
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Reducing clinical trial eligibility barriers for patients with MDS: an icMDS position statement. Blood. 2025 Mar 27; 145(13):1369-1381.
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On the use of external controls in clinical trials. J Natl Cancer Inst Monogr. 2025 Mar 01; 2025(68):30-34.
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Design and analysis considerations for investigating patient subgroups of interest within cancer clinical trials. J Natl Cancer Inst Monogr. 2025 Mar 01; 2025(68):22-29.
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Oncologic Outcomes with De-Escalation of Axillary Surgery After Neoadjuvant Chemotherapy for Breast Cancer: Results from > 1500 Patients on the I-SPY2 Clinical Trial. Ann Surg Oncol. 2025 May; 32(5):3278-3291.
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Augmenting clinical trials in asthma through digital technology, decentralised designs, and person-centric endpoints: opportunities and challenges. Lancet Respir Med. 2025 Feb; 13(2):177-188.
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Lessons Learned from National Heart, Lung, and Blood Institute Covid-19 Clinical Trials. NEJM Evid. 2024 Nov; 3(11):EVIDctcs2300291.
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Clinical Trial Design Considerations for Hospitalised Patients With Ulcerative Colitis Flares and Application to Study Hyperbaric Oxygen Therapy in the NIDDK HBOT-UC Consortium. Aliment Pharmacol Ther. 2024 Dec; 60(11-12):1512-1524.
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The tyranny of non-inferiority trials. Lancet Oncol. 2024 Oct; 25(10):e520-e525.