Internal Ribosome Entry Sites
"Internal Ribosome Entry Sites" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Sequences within MESSENGER RNA that enable PROTEIN TRANSLATION INITIATION independent of 5' CAPPED RNA.
| Descriptor ID |
D000067556
|
| MeSH Number(s) |
D13.444.735.790.878.942.250 G02.111.570.080.689.687.093 G05.360.080.689.687.093
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Internal Ribosome Entry Sites".
Below are MeSH descriptors whose meaning is more specific than "Internal Ribosome Entry Sites".
This graph shows the total number of publications written about "Internal Ribosome Entry Sites" by people in this website by year, and whether "Internal Ribosome Entry Sites" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 2 | 0 | 2 |
| 2018 | 1 | 1 | 2 |
| 2019 | 2 | 1 | 3 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Internal Ribosome Entry Sites" by people in Profiles.
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RNA-based translation activators for targeted gene upregulation. Nat Commun. 2023 10 26; 14(1):6827.
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Synthetic Antibody Binding to a Preorganized RNA Domain of Hepatitis C Virus Internal Ribosome Entry Site Inhibits Translation. ACS Chem Biol. 2020 01 17; 15(1):205-216.
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A conserved RNA structural motif for organizing topology within picornaviral internal ribosome entry sites. Nat Commun. 2019 08 09; 10(1):3629.
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a1ACT Is Essential for Survival and Early Cerebellar Programming in a Critical Neonatal Window. Neuron. 2019 05 22; 102(4):770-785.e7.
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Targeting the CACNA1A IRES as a Treatment for Spinocerebellar Ataxia Type 6. Cerebellum. 2018 02; 17(1):72-77.
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Spinocerebellar [corrected] Ataxia Type 6: Molecular Mechanisms and Calcium Channel Genetics. Adv Exp Med Biol. 2018; 1049:147-173.
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Mammalian Polycistronic mRNAs and Disease. Trends Genet. 2017 02; 33(2):129-142.
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An miRNA-mediated therapy for SCA6 blocks IRES-driven translation of the CACNA1A second cistron. Sci Transl Med. 2016 07 13; 8(347):347ra94.