Mismatch Repair Endonuclease PMS2
"Mismatch Repair Endonuclease PMS2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A MutL protein and component of the DNA MISMATCH REPAIR system. Its ENDONUCLEASE activity introduces SINGLE-STRAND DNA BREAKS which create entry points for EXO1 exonuclease to remove the strand containing the mismatch. It may also function in DNA DAMAGE signaling.
|Mismatch Repair Endonuclease PMS2
- Mismatch Repair Endonuclease PMS2
- PMS1 Homolog 2, Mismatch Repair Protein
- PMS2 Protein
- Postmeiotic Segregation Increased-S. cerevisiae-2
- Postmeiotic Segregation Increased S. cerevisiae 2
- PMS-2 Protein
- PMS 2 Protein
Below are MeSH descriptors whose meaning is more general than "Mismatch Repair Endonuclease PMS2".
Below are MeSH descriptors whose meaning is more specific than "Mismatch Repair Endonuclease PMS2".
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Below are the most recent publications written about "Mismatch Repair Endonuclease PMS2" by people in Profiles.
Endometrial Carcinomas With Subclonal Loss of Mismatch Repair Proteins: A Clinicopathologic and Genomic Study. Am J Surg Pathol. 2023 05 01; 47(5):589-598.
Clinical-Grade Detection of Microsatellite Instability in Colorectal Tumors by Deep Learning. Gastroenterology. 2020 10; 159(4):1406-1416.e11.
Interpretation of Mismatch Repair Protein Immunohistochemistry in Endometrial Carcinoma Should Consider Both Lynch Syndrome Screening and Immunotherapy Susceptibility: An Illustrative Case Report. Int J Gynecol Pathol. 2020 May; 39(3):233-237.
Implication of DNA repair genes in Lynch-like syndrome. Fam Cancer. 2019 07; 18(3):331-342.
Incidence of Mismatch Repair Protein Deficiency and Associated Clinicopathologic Features in a Cohort of 104 Ovarian Endometrioid Carcinomas. Am J Surg Pathol. 2019 02; 43(2):235-243.
Immunohistochemistry for mismatch repair protein deficiency in endometrioid endometrial carcinoma yields equivalent results when performed on endometrial biopsy/curettage or hysterectomy specimens. Gynecol Oncol. 2018 06; 149(3):570-574.
Colorectal Carcinomas With Isolated Loss of PMS2 Staining by Immunohistochemistry. Arch Pathol Lab Med. 2018 Apr; 142(4):523-528.
Associations Between Cancer Predisposition Testing Panel Genes and Breast Cancer. JAMA Oncol. 2017 Sep 01; 3(9):1190-1196.
Mismatch Repair Protein Expression in Clear Cell Carcinoma of the Ovary: Incidence and Morphologic Associations in 109 Cases. Am J Surg Pathol. 2016 May; 40(5):656-63.
Synchronous glioblastoma and medulloblastoma in a child with mismatch repair mutation. Childs Nerv Syst. 2016 Mar; 32(3):553-7.