"Proof of Concept Study" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An empirical investigation which pertains to the development of prototypes or models that demonstrate the feasibility of novel concepts, ideas, principles, schema or their practical application.
Descriptor ID 
D000075082

MeSH Number(s) 
H01.770.644.578

Concept/Terms 
Proof of Concept Study Proof of Concept Study
 Concept Study Proof
 Study Proof, Concept
 Proof of Concept Investigation
 Concept Investigation Proof
 Investigation Proof, Concept
 Proof of Concept Research
 Concept Research Proof
 Concept Research Proofs
 Research Proof, Concept
 Proof of Concept Testing
 Concept Testing Proof
 Concept Testing Proofs
 Testing Proof, Concept
 Testing Proofs, Concept
 Proof of Concept Experiment
 Concept Experiment Proof
 Concept Experiment Proofs
 Experiment Proof, Concept
 Proof of Concept Approach
 Approach Proof, Concept
 Approach Proofs, Concept
 Concept Approach Proof
 Concept Approach Proofs
 Proof of Concept Studies
Proof of Concept Prototype Proof of Concept Prototype
 Concept Prototype Proof
 Concept Prototype Proofs
 Prototype Proof, Concept
 Proof of Concept Model
 Concept Model Proof
 Concept Model Proofs
 Model Proof, Concept
Proof of Concept Evaluation Proof of Concept Evaluation
 Concept Evaluation Proof
 Concept Evaluation Proofs
 Evaluation Proof, Concept
 Proof of Concept Demonstration
 Concept Demonstration Proof
 Demonstration Proof, Concept

Below are MeSH descriptors whose meaning is more general than "Proof of Concept Study".
Below are MeSH descriptors whose meaning is more specific than "Proof of Concept Study".
This graph shows the total number of publications written about "Proof of Concept Study" by people in this website by year, and whether "Proof of Concept Study" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year  Major Topic  Minor Topic  Total 

2017  0  1  1 
2018  0  5  5 
2019  1  4  5 
2020  1  5  6 
2021  0  3  3 
2022  0  1  1 
To return to the timeline,
click here.
Below are the most recent publications written about "Proof of Concept Study" by people in Profiles.

Implications of Heart Rate in Patients with Left Ventricular Assist Devices. Int Heart J. 2022; 63(1):5661.

EarlyLife Microbial Restitution Reduces Colitis Risk Promoted by AntibioticInduced Gut Dysbiosis in Interleukin 10/ Mice. Gastroenterology. 2021 09; 161(3):940952.e15.

T Cell Receptor Repertoires Acquired via Routine Pap Testing May Help Refine Cervical Cancer and Precancer Risk Estimates. Front Immunol. 2021; 12:624230.

Targeting RLIP with CRISPR/Cas9 controls tumor growth. Carcinogenesis. 2021 Feb 11; 42(1):4857.

Small Animal IMRT Using 3DPrinted Compensators. Int J Radiat Oncol Biol Phys. 2021 06 01; 110(2):551565.

Deep learningbased realtime volumetric imaging for lung stereotactic body radiation therapy: a proof of concept study. Phys Med Biol. 2020 12 18; 65(23):235003.

Natural bladder filling alters resting brain function at multiple spatial scales: a proofofconcept MAPP Network Neuroimaging Study. Sci Rep. 2020 11 16; 10(1):19901.

Optimal Continuous Positive Airway Pressure Treatment of Obstructive Sleep Apnea Reduces Daytime Resting Heart Rate in Prediabetes: A Randomized Controlled Study. J Am Heart Assoc. 2020 10 20; 9(19):e016871.

Combining clinical and candidate gene data into a risk score for azathioprineassociated leukopenia in routine clinical practice. Pharmacogenomics J. 2020 10; 20(5):736745.

A randomised controlled study of high intensity exercise as a dishabituating stimulus to improve hypoglycaemia awareness in people with type 1 diabetes: a proofofconcept study. Diabetologia. 2020 04; 63(4):853863.