Sodium-Hydrogen Exchanger 3
"Sodium-Hydrogen Exchanger 3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A sodium-hydrogen antiporter expressed primarily by EPITHELIAL CELLS in the kidneys, it localizes to the apical membrane of the PROXIMAL KIDNEY TUBULE, where it functions in sodium and water reabsorption and possibly calcium homeostasis. It also is expressed in heart, brain, and lung tissues and is resistant to AMILORIDE inhibition.
|Sodium-Hydrogen Exchanger 3
- Sodium-Hydrogen Exchanger 3
- Sodium Hydrogen Exchanger 3
- Na(+)-H(+) Exchanger 3
- Solute Carrier Family 9 Member 3
- NHE-3 Protein
- NHE 3 Protein
- SLC9A3 Protein
Below are MeSH descriptors whose meaning is more general than "Sodium-Hydrogen Exchanger 3".
Below are MeSH descriptors whose meaning is more specific than "Sodium-Hydrogen Exchanger 3".
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Below are the most recent publications written about "Sodium-Hydrogen Exchanger 3" by people in Profiles.
Small Intestinal Phosphate Absorption: Novel Therapeutic Implications. Am J Nephrol. 2021; 52(7):522-530.
Evidence for a role of PDZ domain-containing proteins to mediate hypophosphatemia in calcium stone formers. Nephrol Dial Transplant. 2018 05 01; 33(5):759-770.
D-glucose acts via sodium/glucose cotransporter 1 to increase NHE3 in mouse jejunal brush border by a Na+/H+ exchange regulatory factor 2-dependent process. Gastroenterology. 2011 Feb; 140(2):560-71.
Preserved Na(+)/H(+) exchanger isoform 3 expression and localization, but decreased NHE3 function indicate regulatory sodium transport defect in ulcerative colitis. Inflamm Bowel Dis. 2010 Jul; 16(7):1149-61.
Cyclic AMP-mediated endocytosis of intestinal epithelial NHE3 requires binding to synaptotagmin 1. Am J Physiol Gastrointest Liver Physiol. 2010 Feb; 298(2):G203-11.
Alpha2-adrenergic receptors attenuate secretagogue-induced endocytosis and promote exocytosis of intestinal NHE2 and NHE3. J Pharmacol Exp Ther. 2009 Sep; 330(3):818-25.
Intestinal anion exchanger down-regulated in adenoma (DRA) is inhibited by intracellular calcium. J Biol Chem. 2009 Jul 17; 284(29):19744-53.
Angiotensin II directly regulates intestinal epithelial NHE3 in Caco2BBE cells. BMC Physiol. 2009 Apr 01; 9:5.
Functional coupling of the downregulated in adenoma Cl-/base exchanger DRA and the apical Na+/H+ exchangers NHE2 and NHE3. Am J Physiol Gastrointest Liver Physiol. 2009 Feb; 296(2):G202-10.
Loss of vitamin D receptor produces polyuria by increasing thirst. J Am Soc Nephrol. 2008 Dec; 19(12):2396-405.