Antioxidant Response Elements
"Antioxidant Response Elements" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Nucleotide sequences that are found in the PROMOTER REGIONS of the genes of stress-responsive and cytoprotective proteins, such as those encoding antioxidant and PHASE II DETOXIFICATION enzymes. NF-E2-RELATED FACTOR 2 containing transcription factors bind to these elements during induction of these genes.
| Descriptor ID |
D061745
|
| MeSH Number(s) |
G02.111.570.080.689.675.700.040 G05.360.080.689.675.700.040 G05.360.340.024.340.137.750.680.765.040
|
| Concept/Terms |
Antioxidant Response Elements- Antioxidant Response Elements
- Antioxidant Response Element
- Element, Antioxidant Response
- Elements, Antioxidant Response
- Response Element, Antioxidant
- Response Elements, Antioxidant
- Anti-Oxidant Response Elements
- Anti Oxidant Response Elements
- Anti-Oxidant Response Element
- Element, Anti-Oxidant Response
- Elements, Anti-Oxidant Response
- Response Element, Anti-Oxidant
- Response Elements, Anti-Oxidant
Electrophile Response Elements- Electrophile Response Elements
- Electrophile Response Element
- Element, Electrophile Response
- Elements, Electrophile Response
- Response Element, Electrophile
- Response Elements, Electrophile
|
Below are MeSH descriptors whose meaning is more general than "Antioxidant Response Elements".
Below are MeSH descriptors whose meaning is more specific than "Antioxidant Response Elements".
This graph shows the total number of publications written about "Antioxidant Response Elements" by people in this website by year, and whether "Antioxidant Response Elements" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 2 | 1 | 3 |
| 2023 | 1 | 0 | 1 |
| 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "Antioxidant Response Elements" by people in Profiles.
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The Glucocorticoid Receptor Inhibits NRF2-Mediated Expression of SLC7A11. Free Radic Biol Med. 2025 Dec 16; 241:53-63.
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An antioxidant response element regulates the HIF1a axis in breast cancer cells. Free Radic Biol Med. 2023 08 01; 204:243-251.
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A metabolite-derived protein modification integrates glycolysis with KEAP1-NRF2 signalling. Nature. 2018 10; 562(7728):600-604.
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Identification of a functional antioxidant response element at the HIF1A locus. Redox Biol. 2018 10; 19:401-411.
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A distinct class of antioxidant response elements is consistently activated in tumors with NRF2 mutations. Redox Biol. 2018 10; 19:235-249.
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A hypermorphic antioxidant response element is associated with increased MS4A6A expression and Alzheimer's disease. Redox Biol. 2018 04; 14:686-693.
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Beyond antioxidant genes in the ancient Nrf2 regulatory network. Free Radic Biol Med. 2015 Nov; 88(Pt B):452-465.