ATP Binding Cassette Transporter 1
"ATP Binding Cassette Transporter 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A superfamily of large integral ATP-binding cassette membrane proteins whose expression pattern is consistent with a role in lipid (cholesterol) efflux. It is implicated in TANGIER DISEASE characterized by accumulation of cholesteryl ester in various tissues.
| Descriptor ID |
D064286
|
| MeSH Number(s) |
D12.776.157.530.100.190.500 D12.776.395.550.020.381.500 D12.776.543.550.192.381.500 D12.776.543.585.100.190.500
|
| Concept/Terms |
ATP Binding Cassette Transporter 1- ATP Binding Cassette Transporter 1
- ATP-Binding Cassette Sub-Family A Member 1
- ATP Binding Cassette Sub Family A Member 1
- CERP Protein
- Protein, CERP
- ABCA1 Protein
- Protein, ABCA1
- Cholesterol-Efflux Regulatory Protein
- Cholesterol Efflux Regulatory Protein
- Protein, Cholesterol-Efflux Regulatory
- Regulatory Protein, Cholesterol-Efflux
|
Below are MeSH descriptors whose meaning is more general than "ATP Binding Cassette Transporter 1".
Below are MeSH descriptors whose meaning is more specific than "ATP Binding Cassette Transporter 1".
This graph shows the total number of publications written about "ATP Binding Cassette Transporter 1" by people in this website by year, and whether "ATP Binding Cassette Transporter 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "ATP Binding Cassette Transporter 1" by people in Profiles.
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Is reverse cholesterol transport regulated by active cholesterol? J Lipid Res. 2023 06; 64(6):100385.
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Proteomic analysis of HDL from inbred mouse strains implicates APOE associated with HDL in reduced cholesterol efflux capacity via the ABCA1 pathway. J Lipid Res. 2016 Feb; 57(2):246-57.
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Rho-associated coiled-coil-containing kinase 2 deficiency in bone marrow-derived cells leads to increased cholesterol efflux and decreased atherosclerosis. Circulation. 2012 Oct 30; 126(18):2236-47.
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The ABC transporters and the thickening cholesterol plot. Curr Opin Lipidol. 2011 Feb; 22(1):72-3.
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High-density lipoprotein function in regulating insulin secretion: possible relevance to metabolic syndrome. Arterioscler Thromb Vasc Biol. 2010 Aug; 30(8):1497-9.
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Palmitoylation of ATP-binding cassette transporter A1 is essential for its trafficking and function. Circ Res. 2009 Jul 17; 105(2):138-47.
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Distinct cellular loci for the ABCA1-dependent and ABCA1-independent lipid efflux mediated by endogenous apolipoprotein E expression. Arterioscler Thromb Vasc Biol. 2006 Jan; 26(1):157-62.
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Effects of D-4F on vasodilation and vessel wall thickness in hypercholesterolemic LDL receptor-null and LDL receptor/apolipoprotein A-I double-knockout mice on Western diet. Circ Res. 2005 Nov 25; 97(11):1190-7.
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[SNP collection, pharmacogenomics, and the future of drug therapy]. Gan To Kagaku Ryoho. 2002 Sep; 29(9):1665-73.