"Connectin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A giant elastic protein of molecular mass ranging from 2,993 kDa (cardiac), 3,300 kDa (psoas), to 3,700 kDa (soleus) having a kinase domain. The amino- terminal is involved in a Z line binding, and the carboxy-terminal region is bound to the myosin filament with an overlap between the counter-connectin filaments at the M line.
| Descriptor ID |
D064211
|
| MeSH Number(s) |
D08.811.913.696.620.682.324 D12.776.210.500.246
|
| Concept/Terms |
Myomesin- Myomesin
- M-Line 185 kDa Protein
- M Line 185 kDa Protein
- M-Protein (muscle)
- Muscle M-Line Protein
- M-Line Protein, Muscle
- Muscle M Line Protein
- Protein, Muscle M-Line
- Skelemins
- M-Band Proteins
- M Band Proteins
- Proteins, M-Band
|
Below are MeSH descriptors whose meaning is more general than "Connectin".
Below are MeSH descriptors whose meaning is more specific than "Connectin".
This graph shows the total number of publications written about "Connectin" by people in this website by year, and whether "Connectin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "Connectin" by people in Profiles.
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Substrate Characterization and Outcomes of Ventricular Tachycardia Ablation in TTN (Titin) Cardiomyopathy: A Multicenter Study. Circ Arrhythm Electrophysiol. 2021 09; 14(9):e010006.
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Myofilaments: Movers and Rulers of the Sarcomere. Compr Physiol. 2017 03 16; 7(2):675-692.
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Whole-Exome Sequencing Identifies Two Novel TTN Mutations in Chinese Families with Dilated Cardiomyopathy. Cardiology. 2017; 136(1):10-14.
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Population-based variation in cardiomyopathy genes. Circ Cardiovasc Genet. 2012 Aug 01; 5(4):391-9.
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Genetics: broken giant linked to heart failure. Nature. 2012 Mar 14; 483(7389):281-2.
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A new direction for titin pulling. Proc Natl Acad Sci U S A. 2009 Aug 11; 106(32):13149-50.
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Dysferlin protein analysis in limb-girdle muscular dystrophies. J Mol Neurosci. 2001 Aug; 17(1):71-80.
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TTID: A novel gene at 5q31 encoding a protein with titin-like features. Genomics. 1999 Sep 01; 60(2):226-33.
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Striational autoantibodies in myasthenia gravis patients recognize I-band titin epitopes. J Neuroimmunol. 1998 Jan; 81(1-2):98-108.
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Patients with myasthenia gravis and thymoma have in their sera IgG autoantibodies against titin. Clin Exp Immunol. 1990 Nov; 82(2):284-8.