"Hepcidins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Forms of hepcidin, a cationic amphipathic peptide synthesized in the liver as a prepropeptide which is first processed into prohepcidin and then into the biologically active hepcidin forms, including in human the 20-, 22-, and 25-amino acid residue peptide forms. Hepcidin acts as a homeostatic regulators of iron metabolism and also possesses antimicrobial activity.
| Descriptor ID |
D064451
|
| MeSH Number(s) |
D12.776.494.249 D12.776.543.695.054.425
|
| Concept/Terms |
Hepcidins- Hepcidins
- Liver-Expressed Antimicrobial Peptide
- Antimicrobial Peptide, Liver-Expressed
- Liver Expressed Antimicrobial Peptide
- Peptide, Liver-Expressed Antimicrobial
- Hepcidin
|
Below are MeSH descriptors whose meaning is more general than "Hepcidins".
Below are MeSH descriptors whose meaning is more specific than "Hepcidins".
This graph shows the total number of publications written about "Hepcidins" by people in this website by year, and whether "Hepcidins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Hepcidins" by people in Profiles.
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Ziltivekimab for Treatment of Anemia of Inflammation in Patients on Hemodialysis: Results from a Phase 1/2 Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial. J Am Soc Nephrol. 2021 01; 32(1):211-222.
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LEAP2 Is an Endogenous Antagonist of the Ghrelin Receptor. Cell Metab. 2018 02 06; 27(2):461-469.e6.
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Plasma hepcidin of Ethiopian highlanders with steady-state hypoxia. Blood. 2013 Sep 12; 122(11):1989-91.
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Iron deficiency and raised hepcidin in idiopathic pulmonary arterial hypertension: clinical prevalence, outcomes, and mechanistic insights. J Am Coll Cardiol. 2011 Jul 12; 58(3):300-9.