"Cytochrome P-450 CYP2C8" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A liver microsomal cytochrome P450 hydroxylase that oxidizes a broad spectrum of substrates including STEROIDS, FATTY ACIDS, and XENOBIOTICS. Examples of pharmaceutical substrates for CYP2C8 include; PACLITAXOL; torsemide; and; AMODIAQUINE
| Descriptor ID |
D065727
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| MeSH Number(s) |
D08.244.453.005.590 D08.244.453.491.368 D08.811.682.690.708.170.010.590 D08.811.682.690.708.170.450.360 D12.776.422.220.453.010.590 D12.776.422.220.453.491.360
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| Concept/Terms |
Cytochrome P-450 CYP2C8- Cytochrome P-450 CYP2C8
- CYP2C8, Cytochrome P-450
- Cytochrome P 450 CYP2C8
- P-450 CYP2C8, Cytochrome
- Cytochrome P450 MP-20
- Cytochrome P450 MP 20
- P450 MP-20, Cytochrome
- Cytochrome P450, Family 2, Subfamily C, Polypeptide 8
- S-Mephenytoin 4-Hydroxylase
- 4-Hydroxylase, S-Mephenytoin
- S Mephenytoin 4 Hydroxylase
- CYP2C8
- CYPIIC8
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Below are MeSH descriptors whose meaning is more general than "Cytochrome P-450 CYP2C8".
Below are MeSH descriptors whose meaning is more specific than "Cytochrome P-450 CYP2C8".
This graph shows the total number of publications written about "Cytochrome P-450 CYP2C8" by people in this website by year, and whether "Cytochrome P-450 CYP2C8" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
| 2013 | 0 | 2 | 2 |
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Below are the most recent publications written about "Cytochrome P-450 CYP2C8" by people in Profiles.
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Are drug labels static or dynamic? Clin Pharmacol Ther. 2013 Sep; 94(3):302-4.
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Prevalence of CYP2C8 polymorphisms in a North Indian population. Genet Mol Res. 2013 Jul 08; 12(3):2260-6.
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Role of cytochrome P450 2C8 and 2J2 genotypes in calcineurin inhibitor-induced chronic kidney disease. Pharmacogenet Genomics. 2008 Nov; 18(11):943-53.