"Deoxyribonuclease I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme capable of hydrolyzing highly polymerized DNA by splitting phosphodiester linkages, preferentially adjacent to a pyrimidine nucleotide. This catalyzes endonucleolytic cleavage of DNA yielding 5'-phosphodi- and oligonucleotide end-products. The enzyme has a preference for double-stranded DNA.
| Descriptor ID |
D003850
|
| MeSH Number(s) |
D08.811.277.352.335.350.250
|
| Concept/Terms |
Deoxyribonuclease I- Deoxyribonuclease I
- DNAase I
- Pancreatic DNase
- DNase, Pancreatic
- Thymonuclease
- DNA Endonuclease
- Endonuclease, DNA
- DNase I
Nickase- Nickase
- DNA Nicking Enzyme
- Endonuclease I
|
Below are MeSH descriptors whose meaning is more general than "Deoxyribonuclease I".
Below are MeSH descriptors whose meaning is more specific than "Deoxyribonuclease I".
This graph shows the total number of publications written about "Deoxyribonuclease I" by people in this website by year, and whether "Deoxyribonuclease I" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 1 | 2 |
| 2002 | 1 | 2 | 3 |
| 2006 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2012 | 2 | 2 | 4 |
| 2013 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Deoxyribonuclease I" by people in Profiles.
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An Improved Method for Bacterial Immunofluorescence Staining To Eliminate Antibody Exclusion from the Fixed Nucleoid. Biochemistry. 2019 11 12; 58(45):4457-4465.
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Dead or alive: Deoxyribonuclease I sensitive bacteria and implications for the sinus microbiome. Am J Rhinol Allergy. 2016 Mar-Apr; 30(2):94-8.
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The bacterial response regulator ArcA uses a diverse binding site architecture to regulate carbon oxidation globally. PLoS Genet. 2013; 9(10):e1003839.
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Controls of nucleosome positioning in the human genome. PLoS Genet. 2012; 8(11):e1003036.
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Genomics: ENCODE explained. Nature. 2012 Sep 06; 489(7414):52-5.
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The accessible chromatin landscape of the human genome. Nature. 2012 Sep 06; 489(7414):75-82.
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DNase?I sensitivity QTLs are a major determinant of human expression variation. Nature. 2012 Feb 05; 482(7385):390-4.
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Dissecting the regulatory architecture of gene expression QTLs. Genome Biol. 2012 Jan 31; 13(1):R7.
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Heritable individual-specific and allele-specific chromatin signatures in humans. Science. 2010 Apr 09; 328(5975):235-9.
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In the Staphylococcus aureus two-component system sae, the response regulator SaeR binds to a direct repeat sequence and DNA binding requires phosphorylation by the sensor kinase SaeS. J Bacteriol. 2010 Apr; 192(8):2111-27.