 Disease Models, Animal
"Disease Models, Animal" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.
| Descriptor ID |
D004195
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| MeSH Number(s) |
C22.232 E05.598.500 E05.599.395.080
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Disease Models, Animal".
Below are MeSH descriptors whose meaning is more specific than "Disease Models, Animal".
This graph shows the total number of publications written about "Disease Models, Animal" by people in this website by year, and whether "Disease Models, Animal" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 1 | 3 | 4 | | 1981 | 0 | 3 | 3 | | 1982 | 0 | 1 | 1 | | 1983 | 1 | 3 | 4 | | 1984 | 4 | 6 | 10 | | 1985 | 1 | 2 | 3 | | 1986 | 1 | 4 | 5 | | 1987 | 0 | 8 | 8 | | 1988 | 1 | 8 | 9 | | 1989 | 1 | 4 | 5 | | 1990 | 4 | 6 | 10 | | 1991 | 2 | 6 | 8 | | 1992 | 3 | 14 | 17 | | 1993 | 4 | 6 | 10 | | 1994 | 2 | 11 | 13 | | 1995 | 1 | 11 | 12 | | 1996 | 3 | 12 | 15 | | 1997 | 3 | 13 | 16 | | 1998 | 1 | 20 | 21 | | 1999 | 3 | 13 | 16 | | 2000 | 2 | 24 | 26 | | 2001 | 8 | 25 | 33 | | 2002 | 4 | 32 | 36 | | 2003 | 7 | 26 | 33 | | 2004 | 7 | 30 | 37 | | 2005 | 10 | 47 | 57 | | 2006 | 8 | 48 | 56 | | 2007 | 12 | 62 | 74 | | 2008 | 10 | 50 | 60 | | 2009 | 9 | 67 | 76 | | 2010 | 19 | 64 | 83 | | 2011 | 8 | 68 | 76 | | 2012 | 8 | 59 | 67 | | 2013 | 14 | 90 | 104 | | 2014 | 9 | 71 | 80 | | 2015 | 8 | 91 | 99 | | 2016 | 8 | 78 | 86 | | 2017 | 7 | 77 | 84 | | 2018 | 3 | 68 | 71 | | 2019 | 6 | 72 | 78 | | 2020 | 1 | 53 | 54 | | 2021 | 1 | 32 | 33 |
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Below are the most recent publications written about "Disease Models, Animal" by people in Profiles.
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Jacobson RA, Williamson AJ, Wienholts K, Gaines S, Hyoju S, van Goor H, Zaborin A, Shogan BD, Zaborina O, Alverdy JC. Prevention of Anastomotic Leak Via Local Application of Tranexamic Acid to Target Bacterial-mediated Plasminogen Activation: A Practical Solution to a Complex Problem. Ann Surg. 2021 12 01; 274(6):e1038-e1046.
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Nagler CR. Modern World Influences on the Microbiome and Their Consequences for Immune-Mediated Disease. J Immunol. 2021 10 01; 207(7):1695-1696.
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Marchelletta RR, Krishnan M, Spalinger MR, Placone TW, Alvarez R, Sayoc-Becerra A, Canale V, Shawki A, Park YS, Bernts LH, Myers S, Tremblay ML, Barrett KE, Krystofiak E, Kachar B, McGovern DP, Weber CR, Hanson EM, Eckmann L, McCole DF. T cell protein tyrosine phosphatase protects intestinal barrier function by restricting epithelial tight junction remodeling. J Clin Invest. 2021 09 01; 131(17).
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Pototskiy E, Vinokuroff K, Ojeda A, Major CK, Sharma D, Anderson T, Howard K, Borenstein R, Musto AE. Downregulation of CD40L-CD40 attenuates seizure susceptibility and severity of seizures. Sci Rep. 2021 08 26; 11(1):17262.
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Carmean CM, Mimoto M, Landeche M, Ruiz D, Chellan B, Zhao L, Schulz MC, Dumitrescu AM, Sargis RM. Dietary Selenium Deficiency Partially Mimics the Metabolic Effects of Arsenic. Nutrients. 2021 Aug 23; 13(8).
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Movahedan A, Barba H, Spedale M, Deng N, Arvans D, Nadeem U, Leone V, Chang EB, Theriault B, Skondra D. Gnotobiotic Operations and Assembly for Development of Germ-Free Animal Model of Laser-Induced Choroidal Neovascularization. Transl Vis Sci Technol. 2021 08 02; 10(9):14.
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Paris EA, Bahr JM, Bitterman P, Basu S, Abramowicz JS, Barua A. Incidence of malignant transformation in the oviductal fimbria in laying hens, a preclinical model of spontaneous ovarian cancer. PLoS One. 2021; 16(7):e0255007.
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Girish N, Liu CY, Gadeock S, Gomez ML, Huang Y, Sharifkhodaei Z, Washington MK, Polk DB. Persistence of Lgr5+ colonic epithelial stem cells in mouse models of inflammatory bowel disease. Am J Physiol Gastrointest Liver Physiol. 2021 09 01; 321(3):G308-G324.
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Maifrede S, Le BV, Nieborowska-Skorska M, Golovine K, Sullivan-Reed K, Dunuwille WMB, Nacson J, Hulse M, Keith K, Madzo J, Caruso LB, Gazze Z, Lian Z, Padella A, Chitrala KN, Bartholdy BA, Matlawska-Wasowska K, Di Marcantonio D, Simonetti G, Greiner G, Sykes SM, Valent P, Paietta EM, Tallman MS, Fernandez HF, Litzow MR, Minden MD, Huang J, Martinelli G, Vassiliou GS, Tempera I, Piwocka K, Johnson N, Challen GA, Skorski T. TET2 and DNMT3A Mutations Exert Divergent Effects on DNA Repair and Sensitivity of Leukemia Cells to PARP Inhibitors. Cancer Res. 2021 10 01; 81(19):5089-5101.
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Lopez-Ramirez MA, Lai CC, Soliman SI, Hale P, Pham A, Estrada EJ, McCurdy S, Girard R, Verma R, Moore T, Lightle R, Hobson N, Shenkar R, Poulsen O, Haddad GG, Daneman R, Gongol B, Sun H, Lagarrigue F, Awad IA, Ginsberg MH. Astrocytes propel neurovascular dysfunction during cerebral cavernous malformation lesion formation. J Clin Invest. 2021 07 01; 131(13).
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