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De novo missense variants disrupting protein-protein interactions affect risk for autism through gene co-expression and protein networks in neuronal cell types.
Mechanisms of Neuronal Maintenance and Protection.
Nicotinamide mononucleotide adenylyltransferase uses its NAD+ substrate-binding site to chaperone phosphorylated Tau.
Nmnat restores neuronal integrity by neutralizing mutant Huntingtin aggregate-induced progressive toxicity.
Principal Investigator
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Principal Investigator
Overview
researcher role of
Dickinson, Bryan
contributes to
Chemical biology approaches to probe signaling by protein lipidation