"Glucose-6-Phosphate Isomerase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An aldose-ketose isomerase that catalyzes the reversible interconversion of glucose 6-phosphate and fructose 6-phosphate. In prokaryotic and eukaryotic organisms it plays an essential role in glycolytic and gluconeogenic pathways. In mammalian systems the enzyme is found in the cytoplasm and as a secreted protein. This secreted form of glucose-6-phosphate isomerase has been referred to as autocrine motility factor or neuroleukin, and acts as a cytokine which binds to the AUTOCRINE MOTILITY FACTOR RECEPTOR. Deficiency of the enzyme in humans is an autosomal recessive trait, which results in CONGENITAL NONSPHEROCYTIC HEMOLYTIC ANEMIA.
- Glucose-6-Phosphate Isomerase
- Glucose 6 Phosphate Isomerase
- Isomerase, Glucose-6-Phosphate
- Isomerase, Glucose 6 Phosphate
- Phosphohexose Isomerase
- Isomerase, Phosphohexose
- Glucosephosphate Isomerase
- Isomerase, Glucosephosphate
- Phosphoglucose Isomerase
- Isomerase, Phosphoglucose
Autocrine Motility Factor
- Autocrine Motility Factor
- Motility Factor, Autocrine
- Tumor Autocrine Motility Factor
- Tumor-Cell Autocrine Motility Factor
- Tumor Cell Autocrine Motility Factor
Below are MeSH descriptors whose meaning is more general than "Glucose-6-Phosphate Isomerase".
Below are MeSH descriptors whose meaning is more specific than "Glucose-6-Phosphate Isomerase".
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Below are the most recent publications written about "Glucose-6-Phosphate Isomerase" by people in Profiles.
Insufficient autoantigen presentation and failure of tolerance in a mouse model of rheumatoid arthritis. Arthritis Rheum. 2013 Nov; 65(11):2847-56.
Autoreactive thymic B cells are efficient antigen-presenting cells of cognate self-antigens for T cell negative selection. Proc Natl Acad Sci U S A. 2013 Oct 15; 110(42):17011-6.
Autoreactive T and B cells induce the development of bronchus-associated lymphoid tissue in the lung. Am J Respir Cell Mol Biol. 2013 Apr; 48(4):406-14.
Rituximab specifically depletes short-lived autoreactive plasma cells in a mouse model of inflammatory arthritis. Proc Natl Acad Sci U S A. 2010 Mar 09; 107(10):4658-63.
Depression of Saccharomyces cerevisiae invasive growth on non-glucose carbon sources requires the Snf1 kinase. Mol Microbiol. 2002 Jul; 45(2):453-69.
Lack of genetic differentiation among widely spaced subpopulations of a butterfly with home range behaviour. Heredity (Edinb). 2001 Feb; 86(Pt 2):243-50.
The effect of mating system differences on nucleotide diversity at the phosphoglucose isomerase locus in the plant genus Leavenworthia. Genetics. 1999 Jan; 151(1):343-57.
Neuroleukin: a lymphokine product of lectin-stimulated T cells. Science. 1986 Oct 31; 234(4776):574-81.