 Nicotine
"Nicotine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.
| Descriptor ID |
D009538
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| MeSH Number(s) |
D03.132.760.570 D03.383.725.518
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Nicotine".
Below are MeSH descriptors whose meaning is more specific than "Nicotine".
This graph shows the total number of publications written about "Nicotine" by people in this website by year, and whether "Nicotine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1985 | 0 | 1 | 1 | | 1986 | 0 | 1 | 1 | | 1987 | 1 | 0 | 1 | | 1988 | 0 | 1 | 1 | | 1990 | 1 | 1 | 2 | | 1992 | 2 | 0 | 2 | | 1993 | 1 | 0 | 1 | | 1994 | 2 | 0 | 2 | | 1995 | 2 | 2 | 4 | | 1996 | 1 | 2 | 3 | | 1997 | 0 | 2 | 2 | | 1998 | 2 | 0 | 2 | | 1999 | 3 | 2 | 5 | | 2000 | 2 | 1 | 3 | | 2001 | 2 | 2 | 4 | | 2002 | 2 | 0 | 2 | | 2003 | 3 | 1 | 4 | | 2004 | 2 | 2 | 4 | | 2005 | 2 | 1 | 3 | | 2006 | 5 | 2 | 7 | | 2007 | 5 | 4 | 9 | | 2008 | 4 | 2 | 6 | | 2009 | 4 | 1 | 5 | | 2010 | 1 | 1 | 2 | | 2011 | 4 | 0 | 4 | | 2012 | 5 | 2 | 7 | | 2013 | 3 | 1 | 4 | | 2014 | 1 | 0 | 1 | | 2015 | 1 | 1 | 2 | | 2016 | 5 | 0 | 5 | | 2017 | 5 | 2 | 7 | | 2018 | 2 | 0 | 2 | | 2019 | 1 | 0 | 1 | | 2020 | 1 | 3 | 4 | | 2021 | 2 | 0 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "Nicotine" by people in Profiles.
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Kozlova A, Butler RR, Zhang S, Ujas T, Zhang H, Steidl S, Sanders AR, Pang ZP, Vezina P, Duan J. Sex-specific nicotine sensitization and imprinting of self-administration in rats inform GWAS findings on human addiction phenotypes. Neuropsychopharmacology. 2021 09; 46(10):1746-1756.
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Rest EC, Mermelstein RJ, Hedeker D. Nicotine Dependence in Dual Users of Cigarettes and E-Cigarettes: Common and Distinct Elements. Nicotine Tob Res. 2021 03 19; 23(4):662-668.
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Shiffman S, Ferguson SG, Mao J, Scholl SM, Hedeker D, Tindle HA. Effectiveness of nicotine gum in preventing lapses in the face of temptation to smoke among non-daily smokers: a secondary analysis. Addiction. 2020 11; 115(11):2123-2129.
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Leventhal AM, Mason TB, Kirkpatrick MG, Anderson MK, Levine MD. E-cigarette device power moderates the effects of non-tobacco flavors and nicotine on product appeal in young adults. Addict Behav. 2020 08; 107:106403.
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Chai SH, Leventhal AM, Kirkpatrick MG, Eisenlohr-Moul TA, Rapkin AJ, D'Orazio L, Pang RD. Effectiveness of transdermal nicotine patch in premenopausal female smokers is moderated by within-subject severity of negative affect and physical symptoms. Psychopharmacology (Berl). 2020 Jun; 237(6):1737-1744.
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Lesage E, Sutherland MT, Ross TJ, Salmeron BJ, Stein EA. Nicotine dependence (trait) and acute nicotinic stimulation (state) modulate attention but not inhibitory control: converging fMRI evidence from Go-Nogo and Flanker tasks. Neuropsychopharmacology. 2020 04; 45(5):857-865.
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Leventhal AM, Goldenson NI, Barrington-Trimis JL, Pang RD, Kirkpatrick MG. Effects of non-tobacco flavors and nicotine on e-cigarette product appeal among young adult never, former, and current smokers. Drug Alcohol Depend. 2019 10 01; 203:99-106.
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O'Reilly C, Chapotot F, Pittau F, Mella N, Picard F. Nicotine increases sleep spindle activity. J Sleep Res. 2019 08; 28(4):e12800.
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Wolfman SL, Gill DF, Bogdanic F, Long K, Al-Hasani R, McCall JG, Bruchas MR, McGehee DS. Nicotine aversion is mediated by GABAergic interpeduncular nucleus inputs to laterodorsal tegmentum. Nat Commun. 2018 07 13; 9(1):2710.
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Umana IC, Daniele CA, Miller BA, Abburi C, Gallagher K, Brown MA, Mason P, McGehee DS. Nicotinic modulation of descending pain control circuitry. Pain. 2017 Oct; 158(10):1938-1950.
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