 Nicotine
"Nicotine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.
| Descriptor ID |
D009538
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| MeSH Number(s) |
D03.132.760.570 D03.383.725.518
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Nicotine".
Below are MeSH descriptors whose meaning is more specific than "Nicotine".
This graph shows the total number of publications written about "Nicotine" by people in this website by year, and whether "Nicotine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1985 | 0 | 1 | 1 | | 1986 | 0 | 1 | 1 | | 1987 | 1 | 0 | 1 | | 1988 | 0 | 1 | 1 | | 1990 | 1 | 1 | 2 | | 1992 | 2 | 0 | 2 | | 1993 | 1 | 0 | 1 | | 1994 | 2 | 0 | 2 | | 1995 | 2 | 2 | 4 | | 1996 | 1 | 2 | 3 | | 1997 | 0 | 2 | 2 | | 1998 | 2 | 0 | 2 | | 1999 | 3 | 2 | 5 | | 2000 | 2 | 1 | 3 | | 2001 | 2 | 2 | 4 | | 2002 | 2 | 0 | 2 | | 2003 | 3 | 1 | 4 | | 2004 | 2 | 2 | 4 | | 2005 | 2 | 1 | 3 | | 2006 | 5 | 2 | 7 | | 2007 | 5 | 4 | 9 | | 2008 | 4 | 2 | 6 | | 2009 | 4 | 1 | 5 | | 2010 | 1 | 1 | 2 | | 2011 | 4 | 0 | 4 | | 2012 | 5 | 2 | 7 | | 2013 | 3 | 1 | 4 | | 2014 | 1 | 0 | 1 | | 2015 | 1 | 1 | 2 | | 2016 | 5 | 0 | 5 | | 2017 | 5 | 2 | 7 | | 2018 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Nicotine" by people in Profiles.
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Wolfman SL, Gill DF, Bogdanic F, Long K, Al-Hasani R, McCall JG, Bruchas MR, McGehee DS. Nicotine aversion is mediated by GABAergic interpeduncular nucleus inputs to laterodorsal tegmentum. Nat Commun. 2018 07 13; 9(1):2710.
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Umana IC, Daniele CA, Miller BA, Abburi C, Gallagher K, Brown MA, Mason P, McGehee DS. Nicotinic modulation of descending pain control circuitry. Pain. 2017 Oct; 158(10):1938-1950.
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Palmisano AN, Hudd EC, McQuade CM, de Wit H, Astur RS. The effects of nicotine on conditioning, extinction, and reinstatement in humans. Addict Behav. 2018 Feb; 77:51-58.
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Pang RD, Liautaud MM, Kirkpatrick MG, Huh J, Monterosso J, Leventhal AM. Ovarian Hormones and Transdermal Nicotine Administration Independently and Synergistically Suppress Tobacco Withdrawal Symptoms and Smoking Reinstatement in the Human Laboratory. Neuropsychopharmacology. 2018 03; 43(4):828-837.
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Van Hedger K, Bershad AK, de Wit H. Pharmacological challenge studies with acute psychosocial stress. Psychoneuroendocrinology. 2017 Nov; 85:123-133.
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Govind AP, Vallejo YF, Stolz JR, Yan JZ, Swanson GT, Green WN. Selective and regulated trapping of nicotinic receptor weak base ligands and relevance to smoking cessation. Elife. 2017 07 18; 6.
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Xia J, Meyers AM, Beeler JA. Chronic Nicotine Alters Corticostriatal Plasticity in the Striatopallidal Pathway Mediated By NR2B-Containing Silent Synapses. Neuropsychopharmacology. 2017 Nov; 42(12):2314-2324.
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Lee J, Luria A, Rhodes C, Raghu H, Lingampalli N, Sharpe O, Rada B, Sohn DH, Robinson WH, Sokolove J. Nicotine drives neutrophil extracellular traps formation and accelerates collagen-induced arthritis. Rheumatology (Oxford). 2017 04 01; 56(4):644-653.
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Goldenson NI, Kirkpatrick MG, Barrington-Trimis JL, Pang RD, McBeth JF, Pentz MA, Samet JM, Leventhal AM. Effects of sweet flavorings and nicotine on the appeal and sensory properties of e-cigarettes among young adult vapers: Application of a novel methodology. Drug Alcohol Depend. 2016 Nov 01; 168:176-180.
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Abburi C, Wolfman SL, Metz RA, Kamber R, McGehee DS, McDaid J. Tolerance to Ethanol or Nicotine Results in Increased Ethanol Self-Administration and Long-Term Depression in the Dorsolateral Striatum. eNeuro. 2016 Jul-Aug; 3(4).
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