"Pimozide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A diphenylbutylpiperidine that is effective as an antipsychotic agent and as an alternative to HALOPERIDOL for the suppression of vocal and motor tics in patients with Tourette syndrome. Although the precise mechanism of action is unknown, blockade of postsynaptic dopamine receptors has been postulated. (From AMA Drug Evaluations Annual, 1994, p403)
| Descriptor ID |
D010868
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| MeSH Number(s) |
D03.633.100.103.732
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Pimozide".
Below are MeSH descriptors whose meaning is more specific than "Pimozide".
This graph shows the total number of publications written about "Pimozide" by people in this website by year, and whether "Pimozide" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
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Below are the most recent publications written about "Pimozide" by people in Profiles.
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High dose pimozide does not block amphetamine-induced euphoria in normal volunteers. Pharmacol Biochem Behav. 1997 Feb; 56(2):265-72.
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Subjective responses to d-amphetamine alone and after pimozide pretreatment in normal, healthy volunteers. Biol Psychiatry. 1996 Jan 01; 39(1):26-32.
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The effect of dopamine receptor blockade on the development of sensitization to the locomotor activating effects of amphetamine and morphine. Brain Res. 1989 Oct 09; 499(1):108-20.
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Hyperthermia induced by morphine administration to the VTA of the rat brain: an effect dissociable from morphine-induced reward and hyperactivity. Life Sci. 1985 Mar 18; 36(11):1095-105.