"Mibefradil" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A benzimidazoyl-substituted tetraline that selectively binds and inhibits CALCIUM CHANNELS, T-TYPE.
| Descriptor ID |
D020748
|
| MeSH Number(s) |
D02.455.426.559.847.638.960.585 D03.633.100.103.618 D04.615.638.960.585
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Mibefradil".
Below are MeSH descriptors whose meaning is more specific than "Mibefradil".
This graph shows the total number of publications written about "Mibefradil" by people in this website by year, and whether "Mibefradil" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
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Below are the most recent publications written about "Mibefradil" by people in Profiles.
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An inner pore residue (Asn406) in the Nav1.5 channel controls slow inactivation and enhances mibefradil block to T-type Ca2+ channel levels. Mol Pharmacol. 2006 Nov; 70(5):1514-23.
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State-dependent mibefradil block of Na+ channels. Mol Pharmacol. 2004 12; 66(6):1652-61.
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Comparative effects of selective T- and L-type calcium channel blockers in the remnant kidney model. Hypertension. 2001 May; 37(5):1268-72.
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Mibefradil block of cloned T-type calcium channels. J Pharmacol Exp Ther. 2000 Oct; 295(1):302-8.