 Mice, SCID
"Mice, SCID" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Mice homozygous for the mutant autosomal recessive gene "scid" which is located on the centromeric end of chromosome 16. These mice lack mature, functional lymphocytes and are thus highly susceptible to lethal opportunistic infections if not chronically treated with antibiotics. The lack of B- and T-cell immunity resembles severe combined immunodeficiency (SCID) syndrome in human infants. SCID mice are useful as animal models since they are receptive to implantation of a human immune system producing SCID-human (SCID-hu) hematochimeric mice.
| Descriptor ID |
D016513
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| MeSH Number(s) |
B01.050.150.900.649.865.635.505.500.550.780
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| Concept/Terms |
Mice, SCID- Mice, SCID
- Severe Combined Immunodeficient Mice
- SCID Mice
- Immunodeficient Mice, Severe Combined
- Mouse, SCID
- SCID Mouse
Mouse, SCID-hu- Mouse, SCID-hu
- Mouse, SCID hu
- SCID-hu Mouse
- SCID-hu Mice
- Mice, SCID-hu
- SCID hu Mice
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Below are MeSH descriptors whose meaning is more general than "Mice, SCID".
Below are MeSH descriptors whose meaning is more specific than "Mice, SCID".
This graph shows the total number of publications written about "Mice, SCID" by people in this website by year, and whether "Mice, SCID" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1992 | 0 | 1 | 1 | | 1993 | 1 | 3 | 4 | | 1994 | 1 | 3 | 4 | | 1995 | 0 | 7 | 7 | | 1996 | 1 | 4 | 5 | | 1997 | 3 | 3 | 6 | | 1998 | 2 | 5 | 7 | | 1999 | 0 | 4 | 4 | | 2000 | 1 | 1 | 2 | | 2001 | 0 | 6 | 6 | | 2002 | 0 | 3 | 3 | | 2003 | 0 | 2 | 2 | | 2004 | 0 | 7 | 7 | | 2005 | 0 | 5 | 5 | | 2006 | 0 | 7 | 7 | | 2007 | 0 | 2 | 2 | | 2008 | 0 | 5 | 5 | | 2009 | 0 | 3 | 3 | | 2010 | 0 | 10 | 10 | | 2011 | 0 | 7 | 7 | | 2012 | 0 | 11 | 11 | | 2013 | 0 | 8 | 8 | | 2014 | 0 | 7 | 7 | | 2015 | 0 | 12 | 12 | | 2016 | 0 | 14 | 14 | | 2017 | 0 | 5 | 5 | | 2018 | 0 | 12 | 12 | | 2019 | 0 | 6 | 6 | | 2020 | 0 | 2 | 2 | | 2021 | 0 | 2 | 2 |
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Below are the most recent publications written about "Mice, SCID" by people in Profiles.
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Chen M, Brackett CM, Burdelya LG, Punnanitinont A, Patnaik SK, Matsuzaki J, Odunsi AO, Gudkov AV, Singh AK, Repasky EA, Gurova KV. Stimulation of an anti-tumor immune response with "chromatin-damaging" therapy. Cancer Immunol Immunother. 2021 Jul; 70(7):2073-2086.
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Cheruku RR, Cacaccio J, Durrani FA, Tabaczynski WA, Watson R, Siters K, Missert JR, Tracy EC, Dukh M, Guru K, Koya RC, Kalinski P, Baumann H, Pandey RK. Synthesis, Tumor Specificity, and Photosensitizing Efficacy of Erlotinib-Conjugated Chlorins and Bacteriochlorins: Identification of a Highly Effective Candidate for Photodynamic Therapy of Cancer. J Med Chem. 2021 01 14; 64(1):741-767.
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Gagliardi M, Pitner MK, Park J, Xie X, Saso H, Larson RA, Sammons RM, Chen H, Wei C, Masuda H, Chauhan G, Kondo K, Tripathy D, Ueno NT, Dalby KN, Debeb BG, Bartholomeusz C. Differential functions of ERK1 and ERK2 in lung metastasis processes in triple-negative breast cancer. Sci Rep. 2020 05 22; 10(1):8537.
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Hight SK, Mootz A, Kollipara RK, McMillan E, Yenerall P, Otaki Y, Li LS, Avila K, Peyton M, Rodriguez-Canales J, Mino B, Villalobos P, Girard L, Dospoy P, Larsen J, White MA, Heymach JV, Wistuba II, Kittler R, Minna JD. An in vivo functional genomics screen of nuclear receptors and their co-regulators identifies FOXA1 as an essential gene in lung tumorigenesis. Neoplasia. 2020 08; 22(8):294-310.
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Zhang K, Yang L, Wang J, Sun T, Guo Y, Nelson R, Tong TR, Pangeni R, Salgia R, Raz DJ. Ubiquitin-specific protease 22 is critical to in vivo angiogenesis, growth and metastasis of non-small cell lung cancer. Cell Commun Signal. 2019 12 16; 17(1):167.
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Jung J, Zhang Y, Celiku O, Zhang W, Song H, Williams BJ, Giles AJ, Rich JN, Abounader R, Gilbert MR, Park DM. Mitochondrial NIX Promotes Tumor Survival in the Hypoxic Niche of Glioblastoma. Cancer Res. 2019 10 15; 79(20):5218-5232.
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Wilson DS, Damo M, Hirosue S, Raczy MM, Brünggel K, Diaceri G, Quaglia-Thermes X, Hubbell JA. Synthetically glycosylated antigens induce antigen-specific tolerance and prevent the onset of diabetes. Nat Biomed Eng. 2019 10; 3(10):817-829.
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Driehuis E, Kolders S, Spelier S, Lõhmussaar K, Willems SM, Devriese LA, de Bree R, de Ruiter EJ, Korving J, Begthel H, van Es JH, Geurts V, He GW, van Jaarsveld RH, Oka R, Muraro MJ, Vivié J, Zandvliet MMJM, Hendrickx APA, Iakobachvili N, Sridevi P, Kranenburg O, van Boxtel R, Kops GJPL, Tuveson DA, Peters PJ, van Oudenaarden A, Clevers H. Oral Mucosal Organoids as a Potential Platform for Personalized Cancer Therapy. Cancer Discov. 2019 07; 9(7):852-871.
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Mills KA, Quinn JM, Roach ST, Palisoul M, Nguyen M, Noia H, Guo L, Fazal J, Mutch DG, Wickline SA, Pan H, Fuh KC. p5RHH nanoparticle-mediated delivery of AXL siRNA inhibits metastasis of ovarian and uterine cancer cells in mouse xenografts. Sci Rep. 2019 03 18; 9(1):4762.
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Singhal J, Chikara S, Horne D, Salgia R, Awasthi S, Singhal SS. RLIP inhibition suppresses breast-to-lung metastasis. Cancer Lett. 2019 04 10; 447:24-32.
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