 Conserved Sequence
"Conserved Sequence" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A sequence of amino acids in a polypeptide or of nucleotides in DNA or RNA that is similar across multiple species. A known set of conserved sequences is represented by a CONSENSUS SEQUENCE. AMINO ACID MOTIFS are often composed of conserved sequences.
| Descriptor ID |
D017124
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| MeSH Number(s) |
G02.111.570.580
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| Concept/Terms |
Conserved Sequence- Conserved Sequence
- Conserved Sequences
- Sequence, Conserved
- Sequences, Conserved
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Below are MeSH descriptors whose meaning is more general than "Conserved Sequence".
Below are MeSH descriptors whose meaning is more specific than "Conserved Sequence".
This graph shows the total number of publications written about "Conserved Sequence" by people in this website by year, and whether "Conserved Sequence" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 2 | 2 | 4 | | 1994 | 0 | 5 | 5 | | 1995 | 0 | 7 | 7 | | 1996 | 0 | 5 | 5 | | 1997 | 0 | 6 | 6 | | 1998 | 1 | 8 | 9 | | 1999 | 0 | 5 | 5 | | 2000 | 0 | 4 | 4 | | 2001 | 1 | 4 | 5 | | 2002 | 0 | 7 | 7 | | 2003 | 2 | 6 | 8 | | 2004 | 2 | 13 | 15 | | 2005 | 2 | 7 | 9 | | 2006 | 2 | 12 | 14 | | 2007 | 0 | 5 | 5 | | 2008 | 1 | 11 | 12 | | 2009 | 0 | 2 | 2 | | 2010 | 2 | 5 | 7 | | 2011 | 2 | 4 | 6 | | 2012 | 3 | 5 | 8 | | 2013 | 2 | 8 | 10 | | 2014 | 0 | 7 | 7 | | 2015 | 0 | 3 | 3 | | 2016 | 0 | 4 | 4 | | 2017 | 2 | 5 | 7 | | 2018 | 1 | 6 | 7 | | 2019 | 1 | 2 | 3 | | 2020 | 2 | 2 | 4 |
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Below are the most recent publications written about "Conserved Sequence" by people in Profiles.
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Eres IE, Gilad Y. A TAD Skeptic: Is 3D Genome Topology Conserved? Trends Genet. 2021 03; 37(3):216-223.
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Piltonen M, Krokhotin A, Parisien M, Bérubé P, Djambazian H, Sladek R, Dokholyan NV, Shabalina SA, Diatchenko L. Alternative Splicing of Opioid Receptor Genes Shows a Conserved Pattern for 6TM Receptor Variants. Cell Mol Neurobiol. 2021 Jul; 41(5):1039-1055.
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Winkelman JD, Anderson CA, Suarez C, Kovar DR, Gardel ML. Evolutionarily diverse LIM domain-containing proteins bind stressed actin filaments through a conserved mechanism. Proc Natl Acad Sci U S A. 2020 10 13; 117(41):25532-25542.
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Bloch JS, Pesciullesi G, Boilevin J, Nosol K, Irobalieva RN, Darbre T, Aebi M, Kossiakoff AA, Reymond JL, Locher KP. Structure and mechanism of the ER-based glucosyltransferase ALG6. Nature. 2020 03; 579(7799):443-447.
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Koirala D, Shao Y, Koldobskaya Y, Fuller JR, Watkins AM, Shelke SA, Pilipenko EV, Das R, Rice PA, Piccirilli JA. A conserved RNA structural motif for organizing topology within picornaviral internal ribosome entry sites. Nat Commun. 2019 08 09; 10(1):3629.
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Fang X, Osipiuk J, Chakravarthy S, Yuan M, Menzer WM, Nissen D, Liang P, Raba DA, Tuz K, Howard AJ, Joachimiak A, Minh DDL, Juarez O. Conserved residue His-257 of Vibrio cholerae flavin transferase ApbE plays a critical role in substrate binding and catalysis. J Biol Chem. 2019 09 13; 294(37):13800-13810.
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Cheng S, Ashley J, Kurleto JD, Lobb-Rabe M, Park YJ, Carrillo RA, Özkan E. Molecular basis of synaptic specificity by immunoglobulin superfamily receptors in Drosophila. Elife. 2019 01 28; 8.
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Dobyns WB, Aldinger KA, Ishak GE, Mirzaa GM, Timms AE, Grout ME, Dremmen MHG, Schot R, Vandervore L, van Slegtenhorst MA, Wilke M, Kasteleijn E, Lee AS, Barry BJ, Chao KR, Szczaluba K, Kobori J, Hanson-Kahn A, Bernstein JA, Carr L, D'Arco F, Miyana K, Okazaki T, Saito Y, Sasaki M, Das S, Wheeler MM, Bamshad MJ, Nickerson DA. MACF1 Mutations Encoding Highly Conserved Zinc-Binding Residues of the GAR Domain Cause Defects in Neuronal Migration and Axon Guidance. Am J Hum Genet. 2018 12 06; 103(6):1009-1021.
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Piltonen M, Parisien M, Grégoire S, Chabot-Doré AJ, Jafarnejad SM, Bérubé P, Djambazian H, Sladek R, Geneau G, Willett P, Stone LS, Shabalina SA, Diatchenko L. Alternative Splicing of the Delta-Opioid Receptor Gene Suggests Existence of New Functional Isoforms. Mol Neurobiol. 2019 Apr; 56(4):2855-2869.
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Salinas VH, Ranganathan R. Coevolution-based inference of amino acid interactions underlying protein function. Elife. 2018 07 20; 7.
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