"Binding Sites" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The parts of a macromolecule that directly participate in its specific combination with another molecule.
| Descriptor ID |
D001665
|
| MeSH Number(s) |
G02.111.570.120
|
| Concept/Terms |
Binding Sites- Binding Sites
- Site, Binding
- Sites, Binding
- Binding Site
- Combining Site
- Combining Sites
- Site, Combining
- Sites, Combining
|
Below are MeSH descriptors whose meaning is more general than "Binding Sites".
Below are MeSH descriptors whose meaning is more specific than "Binding Sites".
This graph shows the total number of publications written about "Binding Sites" by people in this website by year, and whether "Binding Sites" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 25 | 25 |
| 1996 | 0 | 24 | 24 |
| 1997 | 0 | 18 | 18 |
| 1998 | 1 | 29 | 30 |
| 1999 | 0 | 30 | 30 |
| 2000 | 0 | 28 | 28 |
| 2001 | 0 | 27 | 27 |
| 2002 | 0 | 39 | 39 |
| 2003 | 0 | 43 | 43 |
| 2004 | 0 | 39 | 39 |
| 2005 | 1 | 32 | 33 |
| 2006 | 0 | 34 | 34 |
| 2007 | 0 | 35 | 35 |
| 2008 | 0 | 27 | 27 |
| 2009 | 0 | 26 | 26 |
| 2010 | 3 | 31 | 34 |
| 2011 | 2 | 30 | 32 |
| 2012 | 0 | 37 | 37 |
| 2013 | 0 | 38 | 38 |
| 2014 | 3 | 25 | 28 |
| 2015 | 0 | 25 | 25 |
| 2016 | 0 | 33 | 33 |
| 2017 | 0 | 22 | 22 |
| 2018 | 0 | 25 | 25 |
| 2019 | 1 | 13 | 14 |
| 2020 | 0 | 21 | 21 |
| 2021 | 0 | 14 | 14 |
| 2022 | 0 | 2 | 2 |
| 2023 | 0 | 7 | 7 |
| 2024 | 0 | 7 | 7 |
| 2025 | 0 | 2 | 2 |
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Below are the most recent publications written about "Binding Sites" by people in Profiles.
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Different chemical scaffolds bind to L-phe site in Mycobacterium tuberculosis Phe-tRNA synthetase. Eur J Med Chem. 2025 Apr 05; 287:117335.
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Chemical-guided SHAPE sequencing (cgSHAPE-seq) informs the binding site of RNA-degrading chimeras targeting SARS-CoV-2 5' untranslated region. Nat Commun. 2025 Jan 08; 16(1):483.
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Binding mode-guided development of high-performance antibodies targeting site-specific posttranslational modifications. Proc Natl Acad Sci U S A. 2025 Jan 07; 122(1):e2411720121.
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Cryo-EM structures of Clostridium perfringens enterotoxin bound to its human receptor, claudin-4. Structure. 2024 Nov 07; 32(11):1936-1951.e5.
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Quantitative analysis of cis-regulatory elements in transcription with KAS-ATAC-seq. Nat Commun. 2024 Aug 10; 15(1):6852.
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Cracked actin filaments as mechanosensitive receptors. Biophys J. 2024 10 01; 123(19):3283-3294.
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Prediction of the essential intermolecular contacts for side-binding of VASP on F-actin. Cytoskeleton (Hoboken). 2024 Aug; 81(8):382-392.
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Profiling of RNA-binding protein binding sites by in situ reverse transcription-based sequencing. Nat Methods. 2024 Feb; 21(2):247-258.
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Interpreting the effect of mutations to protein binding sites from large-scale genomic screens. Methods. 2024 02; 222:122-132.
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Monovalent metal ion binding promotes the first transesterification reaction in the spliceosome. Nat Commun. 2023 Dec 20; 14(1):8482.