 Computational Biology
"Computational Biology" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A field of biology concerned with the development of techniques for the collection and manipulation of biological data, and the use of such data to make biological discoveries or predictions. This field encompasses all computational methods and theories applicable to MOLECULAR BIOLOGY and areas of computer-based techniques for solving biological problems including manipulation of models and datasets.
| Descriptor ID |
D019295
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| MeSH Number(s) |
H01.158.273.180
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Computational Biology".
Below are MeSH descriptors whose meaning is more specific than "Computational Biology".
This graph shows the total number of publications written about "Computational Biology" by people in this website by year, and whether "Computational Biology" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 2 | 2 | | 2000 | 2 | 1 | 3 | | 2001 | 1 | 6 | 7 | | 2002 | 1 | 4 | 5 | | 2003 | 2 | 6 | 8 | | 2004 | 5 | 11 | 16 | | 2005 | 8 | 9 | 17 | | 2006 | 8 | 14 | 22 | | 2007 | 3 | 12 | 15 | | 2008 | 7 | 15 | 22 | | 2009 | 10 | 13 | 23 | | 2010 | 13 | 17 | 30 | | 2011 | 8 | 16 | 24 | | 2012 | 7 | 11 | 18 | | 2013 | 4 | 13 | 17 | | 2014 | 9 | 19 | 28 | | 2015 | 8 | 16 | 24 | | 2016 | 2 | 17 | 19 | | 2017 | 4 | 10 | 14 | | 2018 | 8 | 17 | 25 | | 2019 | 3 | 4 | 7 |
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Below are the most recent publications written about "Computational Biology" by people in Profiles.
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Gilbert JA, Lynch SV. Community ecology as a framework for human microbiome research. Nat Med. 2019 06; 25(6):884-889.
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Zhu Y, Biernacka A, Pardo B, Dojer N, Forey R, Skrzypczak M, Fongang B, Nde J, Yousefi R, Pasero P, Ginalski K, Rowicka M. qDSB-Seq is a general method for genome-wide quantification of DNA double-strand breaks using sequencing. Nat Commun. 2019 05 24; 10(1):2313.
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Gamazon ER, Zwinderman AH, Cox NJ, Denys D, Derks EM. Multi-tissue transcriptome analyses identify genetic mechanisms underlying neuropsychiatric traits. Nat Genet. 2019 06; 51(6):933-940.
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Wu D, Pepowski B, Takahashi S, Kron SJ. A cmap-enabled gene expression signature-matching approach identifies small-molecule inducers of accelerated cell senescence. BMC Genomics. 2019 Apr 15; 20(1):290.
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Park SJ, Lee J, Qi Y, Kern NR, Lee HS, Jo S, Joung I, Joo K, Lee J, Im W. CHARMM-GUI Glycan Modeler for modeling and simulation of carbohydrates and glycoconjugates. Glycobiology. 2019 04 01; 29(4):320-331.
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Plourde SM, Amom P, Tan M, Dawes AT, Dobritsa AA. Changes in morphogen kinetics and pollen grain size are potential mechanisms of aberrant pollen aperture patterning in previously observed and novel mutants of Arabidopsis thaliana. PLoS Comput Biol. 2019 02; 15(2):e1006800.
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Bjoring MC, Meliza CD. A low-threshold potassium current enhances sparseness and reliability in a model of avian auditory cortex. PLoS Comput Biol. 2019 01; 15(1):e1006723.
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Chaterji S, Koo J, Li N, Meyer F, Grama A, Bagchi S. Federation in genomics pipelines: techniques and challenges. Brief Bioinform. 2019 01 18; 20(1):235-244.
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Jumper JM, Faruk NF, Freed KF, Sosnick TR. Trajectory-based training enables protein simulations with accurate folding and Boltzmann ensembles in cpu-hours. PLoS Comput Biol. 2018 12; 14(12):e1006578.
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Lea AJ, Vockley CM, Johnston RA, Del Carpio CA, Barreiro LB, Reddy TE, Tung J. Genome-wide quantification of the effects of DNA methylation on human gene regulation. Elife. 2018 12 21; 7.
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