"Systems Biology" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Comprehensive, methodical analysis of complex biological systems by monitoring responses to perturbations of biological processes. Large scale, computerized collection and analysis of the data are used to develop and test models of biological systems.
| Descriptor ID |
D049490
|
| MeSH Number(s) |
H01.158.273.180.800
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Systems Biology".
Below are MeSH descriptors whose meaning is more specific than "Systems Biology".
This graph shows the total number of publications written about "Systems Biology" by people in this website by year, and whether "Systems Biology" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 1 | 2 |
| 2009 | 1 | 2 | 3 |
| 2010 | 0 | 1 | 1 |
| 2011 | 2 | 4 | 6 |
| 2012 | 3 | 1 | 4 |
| 2013 | 1 | 2 | 3 |
| 2014 | 1 | 2 | 3 |
| 2016 | 3 | 2 | 5 |
| 2017 | 2 | 1 | 3 |
| 2018 | 2 | 2 | 4 |
| 2019 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 2 | 0 | 2 |
| 2023 | 1 | 1 | 2 |
| 2025 | 1 | 1 | 2 |
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Below are the most recent publications written about "Systems Biology" by people in Profiles.
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A Roadmap for the Future of Systems Biology in Cancer Research. Cancer Res. 2025 12 15; 85(24):4880-4889.
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Connectogenomics: edges-first spatial biology. Trends Biotechnol. 2026 Jun; 44(6):1605-1616.
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Systems Immunology Approaches to Metabolism. Annu Rev Immunol. 2023 04 26; 41:317-342.
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Addressing the genetic/nongenetic duality in cancer with systems biology. Trends Cancer. 2023 03; 9(3):185-187.
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Functional biology in its natural context: A search for emergent simplicity. Elife. 2021 06 07; 10.
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Omics sciences for systems biology in Alzheimer's disease: State-of-the-art of the evidence. Ageing Res Rev. 2021 08; 69:101346.
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Interaction profiling methods to map protein and pathway targets of bioactive ligands. Curr Opin Chem Biol. 2020 02; 54:76-84.
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Genome-wide association study identifies 30 loci associated with bipolar disorder. Nat Genet. 2019 05; 51(5):793-803.
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Integrative transcriptome analyses of the aging brain implicate altered splicing in Alzheimer's disease susceptibility. Nat Genet. 2018 11; 50(11):1584-1592.
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Perspectives in melanoma: Meeting report from the Melanoma Bridge (30 November-2 December, 2017, Naples, Italy). J Transl Med. 2018 07 21; 16(1):207.