"Sp3 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A specificity protein transcription factor that contains three C-terminal CYS2-HIS2 ZINC FINGERS. It regulates expression of a variety of genes including VASCULAR ENDOTHELIAL GROWTH FACTOR and CYCLIN-DEPENDENT KINASE INHIBITOR P27.
Descriptor ID |
D051705
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MeSH Number(s) |
D12.776.260.522.750.750 D12.776.930.375.750.750
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Sp3 Transcription Factor".
Below are MeSH descriptors whose meaning is more specific than "Sp3 Transcription Factor".
This graph shows the total number of publications written about "Sp3 Transcription Factor" by people in this website by year, and whether "Sp3 Transcription Factor" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2005 | 0 | 1 | 1 |
2013 | 1 | 0 | 1 |
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Below are the most recent publications written about "Sp3 Transcription Factor" by people in Profiles.
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The transcription factor Sp3 regulates the expression of a metastasis-related marker of sarcoma, actin filament-associated protein 1-like 1 (AFAP1L1). PLoS One. 2013; 8(1):e49709.
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Characterization of the basal promoter element of the human type 5 17beta-hydroxysteroid dehydrogenase gene. Biochim Biophys Acta. 2005 May 01; 1728(3):115-25.
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ESE-1, an enterocyte-specific Ets transcription factor, regulates MIP-3alpha gene expression in Caco-2 human colonic epithelial cells. J Biol Chem. 2003 Jan 10; 278(2):875-84.
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Cloning and characterization of the human heparanase-1 (HPR1) gene promoter: role of GA-binding protein and Sp1 in regulating HPR1 basal promoter activity. J Biol Chem. 2002 Mar 15; 277(11):8989-98.