"Synucleins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of homologous proteins of low MOLECULAR WEIGHT that are predominately expressed in the BRAIN and that have been implicated in a variety of human diseases. They were originally isolated from CHOLINERGIC FIBERS of TORPEDO.
Descriptor ID |
D051843
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MeSH Number(s) |
D12.776.631.860
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Synucleins".
Below are MeSH descriptors whose meaning is more specific than "Synucleins".
This graph shows the total number of publications written about "Synucleins" by people in this website by year, and whether "Synucleins" was a major or minor topic of these publications.
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Below are the most recent publications written about "Synucleins" by people in Profiles.
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Interaction of alpha-synuclein and tau genotypes in Parkinson's disease. Ann Neurol. 2005 Mar; 57(3):439-43.
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Australian data and meta-analysis lend support for alpha-synuclein (NACP-Rep1) as a risk factor for Parkinson's disease. Neurosci Lett. 2005 Feb 28; 375(2):112-6.
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Comparison of kindreds with parkinsonism and alpha-synuclein genomic multiplications. Ann Neurol. 2004 Feb; 55(2):174-9.
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Case-control study of the alpha-synuclein interacting protein gene and Parkinson's disease. Mov Disord. 2003 Nov; 18(11):1233-9.
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alpha-Synuclein locus triplication causes Parkinson's disease. Science. 2003 Oct 31; 302(5646):841.
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Complex interactions in Parkinson's disease: a two-phased approach. Mov Disord. 2003 Jun; 18(6):631-6.
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alpha-Synuclein gene haplotypes are associated with Parkinson's disease. Hum Mol Genet. 2001 Aug 15; 10(17):1847-51.
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Distinctive neuropathology revealed by alpha-synuclein antibodies in hereditary parkinsonism and dementia linked to chromosome 4p. Acta Neuropathol. 2000 Jun; 99(6):663-72.
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Low frequency of alpha-synuclein mutations in familial Parkinson's disease. Ann Neurol. 1998 Mar; 43(3):394-7.