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Lucy Godley to DNA Methylation

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This is a "connection" page, showing publications Lucy Godley has written about DNA Methylation.
Lucy Godley
Connection Strength
5.730
DNA Methylation
  1. MBD4: guardian of the epigenetic galaxy. Blood. 2018 10 04; 132(14):1468-1469.
    View in: PubMed
    Score: 0.494
  2. Characterization of CpG sites that escape methylation on the inactive human X-chromosome. Epigenetics. 2015; 10(9):810-8.
    View in: PubMed
    Score: 0.395
  3. 5-hydroxymethylcytosine in cancer: significance in diagnosis and therapy. Cancer Genet. 2015 May; 208(5):167-77.
    View in: PubMed
    Score: 0.385
  4. The mechanistic role of DNA methylation in myeloid leukemogenesis. Leukemia. 2014 Sep; 28(9):1765-73.
    View in: PubMed
    Score: 0.365
  5. TET1-mediated hydroxymethylation facilitates hypoxic gene induction in neuroblastoma. Cell Rep. 2014 Jun 12; 7(5):1343-1352.
    View in: PubMed
    Score: 0.364
  6. Hydroxymethylation at gene regulatory regions directs stem/early progenitor cell commitment during erythropoiesis. Cell Rep. 2014 Jan 16; 6(1):231-244.
    View in: PubMed
    Score: 0.355
  7. Truncated DNMT3B isoform DNMT3B7 suppresses growth, induces differentiation, and alters DNA methylation in human neuroblastoma. Cancer Res. 2012 Sep 15; 72(18):4714-23.
    View in: PubMed
    Score: 0.321
  8. Molecular biology. Preference by exclusion. Science. 2011 Feb 25; 331(6020):1017-8.
    View in: PubMed
    Score: 0.291
  9. The use of hypomethylating agents in the treatment of hematologic malignancies. Leuk Lymphoma. 2007 Sep; 48(9):1676-95.
    View in: PubMed
    Score: 0.229
  10. MYCN and HIF-1 directly regulate TET1 expression to control 5-hmC gains and enhance neuroblastoma cell migration in hypoxia. Epigenetics. 2022 12; 17(13):2056-2074.
    View in: PubMed
    Score: 0.161
  11. RBL2 bi-allelic truncating variants cause severe motor and cognitive impairment without evidence for abnormalities in DNA methylation or telomeric function. J Hum Genet. 2021 Nov; 66(11):1101-1112.
    View in: PubMed
    Score: 0.148
  12. Regulation of telomeric function by DNA methylation differs between humans and mice. Hum Mol Genet. 2020 11 25; 29(19):3197-3210.
    View in: PubMed
    Score: 0.143
  13. 5-Hydroxymethylcytosine Profiles in Circulating Cell-Free DNA Associate with Disease Burden in Children with Neuroblastoma. Clin Cancer Res. 2020 03 15; 26(6):1309-1317.
    View in: PubMed
    Score: 0.134
  14. Rigosertib versus best supportive care for patients with high-risk myelodysplastic syndromes after failure of hypomethylating drugs (ONTIME): a randomised, controlled, phase 3 trial. Lancet Oncol. 2016 Apr; 17(4):496-508.
    View in: PubMed
    Score: 0.103
  15. Increased DNA methylation of Dnmt3b targets impairs leukemogenesis. Blood. 2016 Mar 24; 127(12):1575-86.
    View in: PubMed
    Score: 0.102
  16. TET2 Mutations Affect Non-CpG Island DNA Methylation at Enhancers and Transcription Factor-Binding Sites in Chronic Myelomonocytic Leukemia. Cancer Res. 2015 Jul 15; 75(14):2833-43.
    View in: PubMed
    Score: 0.098
  17. New themes in the biological functions of 5-methylcytosine and 5-hydroxymethylcytosine. Immunol Rev. 2015 Jan; 263(1):36-49.
    View in: PubMed
    Score: 0.095
  18. The role of gene body cytosine modifications in MGMT expression and sensitivity to temozolomide. Mol Cancer Ther. 2014 May; 13(5):1334-44.
    View in: PubMed
    Score: 0.090
  19. Variability in DNA methylation defines novel epigenetic subgroups of DLBCL associated with different clinical outcomes. Blood. 2014 Mar 13; 123(11):1699-708.
    View in: PubMed
    Score: 0.089
  20. Large conserved domains of low DNA methylation maintained by Dnmt3a. Nat Genet. 2014 Jan; 46(1):17-23.
    View in: PubMed
    Score: 0.088
  21. Mechanism-based epigenetic chemosensitization therapy of diffuse large B-cell lymphoma. Cancer Discov. 2013 Sep; 3(9):1002-19.
    View in: PubMed
    Score: 0.086
  22. Genome-wide variation of cytosine modifications between European and African populations and the implications for complex traits. Genetics. 2013 Aug; 194(4):987-96.
    View in: PubMed
    Score: 0.086
  23. Histone-lysine methyltransferase EHMT2 is involved in proliferation, apoptosis, cell invasion, and DNA methylation of human neuroblastoma cells. Anticancer Drugs. 2013 Jun; 24(5):484-93.
    View in: PubMed
    Score: 0.085
  24. Dnmt3b is a haploinsufficient tumor suppressor gene in Myc-induced lymphomagenesis. Blood. 2013 Mar 14; 121(11):2059-63.
    View in: PubMed
    Score: 0.083
  25. Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis. Nat Genet. 2012 Nov; 44(11):1179-81.
    View in: PubMed
    Score: 0.081
  26. Effects of TET2 mutations on DNA methylation in chronic myelomonocytic leukemia. Epigenetics. 2012 Feb; 7(2):201-7.
    View in: PubMed
    Score: 0.078
  27. Characterization of NOL7 gene point mutations, promoter methylation, and protein expression in cervical cancer. Int J Gynecol Pathol. 2012 Jan; 31(1):15-24.
    View in: PubMed
    Score: 0.077
  28. Dnmt3a is essential for hematopoietic stem cell differentiation. Nat Genet. 2011 Dec 04; 44(1):23-31.
    View in: PubMed
    Score: 0.077
  29. DNA methyltransferase 1 and DNA methylation patterning contribute to germinal center B-cell differentiation. Blood. 2011 Sep 29; 118(13):3559-69.
    View in: PubMed
    Score: 0.075
  30. Inhibition of TET2-mediated conversion of 5-methylcytosine to 5-hydroxymethylcytosine disturbs erythroid and granulomonocytic differentiation of human hematopoietic progenitors. Blood. 2011 Sep 01; 118(9):2551-5.
    View in: PubMed
    Score: 0.075
  31. An integrated genomic approach to the assessment and treatment of acute myeloid leukemia. Semin Oncol. 2011 Apr; 38(2):215-24.
    View in: PubMed
    Score: 0.073
  32. Coordinated cancer germline antigen promoter and global DNA hypomethylation in ovarian cancer: association with the BORIS/CTCF expression ratio and advanced stage. Clin Cancer Res. 2011 Apr 15; 17(8):2170-80.
    View in: PubMed
    Score: 0.073
  33. Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation. Cancer Cell. 2010 Dec 14; 18(6):553-67.
    View in: PubMed
    Score: 0.072
  34. DNMT3B7, a truncated DNMT3B isoform expressed in human tumors, disrupts embryonic development and accelerates lymphomagenesis. Cancer Res. 2010 Jul 15; 70(14):5840-50.
    View in: PubMed
    Score: 0.070
  35. (R)-2-Hydroxyglutarate Inhibits KDM5 Histone Lysine Demethylases to Drive Transformation in IDH-Mutant Cancers. Cancer Discov. 2023 06 02; 13(6):1478-1497.
    View in: PubMed
    Score: 0.043
  36. Mitochondrial superoxide disrupts the metabolic and epigenetic landscape of CD4+ and CD8+ T-lymphocytes. Redox Biol. 2019 10; 27:101141.
    View in: PubMed
    Score: 0.032
  37. DNA Methylation Dynamics of Germinal Center B Cells Are Mediated by AID. Cell Rep. 2015 Sep 29; 12(12):2086-98.
    View in: PubMed
    Score: 0.025
  38. High resolution methylome analysis reveals widespread functional hypomethylation during adult human erythropoiesis. J Biol Chem. 2013 Mar 29; 288(13):8805-14.
    View in: PubMed
    Score: 0.021
  39. Epigenetic regulation of hypoxic sensing disrupts cardiorespiratory homeostasis. Proc Natl Acad Sci U S A. 2012 Feb 14; 109(7):2515-20.
    View in: PubMed
    Score: 0.019
  40. 5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging. Nat Neurosci. 2011 Oct 30; 14(12):1607-16.
    View in: PubMed
    Score: 0.019
  41. Epigenetic alterations differ in phenotypically distinct human neuroblastoma cell lines. BMC Cancer. 2010 Jun 14; 10:286.
    View in: PubMed
    Score: 0.017
  42. Cancer cells express aberrant DNMT3B transcripts encoding truncated proteins. Oncogene. 2007 Aug 16; 26(38):5553-63.
    View in: PubMed
    Score: 0.014
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