Anthony Kossiakoff to Protein Binding
This is a "connection" page, showing publications Anthony Kossiakoff has written about Protein Binding.
Connection Strength
1.943
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Cryo-EM structures of Clostridium perfringens enterotoxin bound to its human receptor, claudin-4. Structure. 2024 11 07; 32(11):1936-1951.e5.
Score: 0.166
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Synthetic antibodies against BRIL as universal fiducial marks for single-particle cryoEM structure determination of membrane proteins. Nat Commun. 2020 03 27; 11(1):1598.
Score: 0.121
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Development of "Plug and Play" Fiducial Marks for Structural Studies of GPCR Signaling Complexes by Single-Particle Cryo-EM. Structure. 2019 12 03; 27(12):1862-1874.e7.
Score: 0.118
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A New Versatile Immobilization Tag Based on the Ultra High Affinity and Reversibility of the Calmodulin-Calmodulin Binding Peptide Interaction. J Mol Biol. 2015 Aug 14; 427(16):2707-25.
Score: 0.087
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Engineering Synthetic Antibody Inhibitors Specific for LD2 or LD4 Motifs of Paxillin. J Mol Biol. 2015 Jul 31; 427(15):2532-2547.
Score: 0.087
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Applications for an engineered Protein-G variant with a pH controllable affinity to antibody fragments. J Immunol Methods. 2014 Dec 15; 415:24-30.
Score: 0.083
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Allosteric control of ligand-binding affinity using engineered conformation-specific effector proteins. Nat Struct Mol Biol. 2011 Apr; 18(4):437-42.
Score: 0.065
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An engineered substance P variant for receptor-mediated delivery of synthetic antibodies into tumor cells. Proc Natl Acad Sci U S A. 2009 Jul 07; 106(27):11011-5.
Score: 0.057
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Principal determinants leading to transition state formation of a protein-protein complex, orientation trumps side-chain interactions. Proc Natl Acad Sci U S A. 2009 Feb 24; 106(8):2559-64.
Score: 0.056
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Understanding mechanisms governing protein-protein interactions from synthetic binding interfaces. Curr Opin Struct Biol. 2008 Aug; 18(4):499-506.
Score: 0.054
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Crystal structure and site 1 binding energetics of human placental lactogen. J Mol Biol. 2006 May 05; 358(3):773-84.
Score: 0.046
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Effect of phosphorylation barcodes on arrestin binding to a chemokine receptor. Nature. 2025 Jul; 643(8070):280-287.
Score: 0.043
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Structural basis for nucleolin recognition of MYC promoter G-quadruplex. Science. 2025 04 18; 388(6744):eadr1752.
Score: 0.043
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Mapping the extracellular molecular architecture of the pAg-signaling complex with a-Butyrophilin antibodies. Sci Rep. 2025 Apr 09; 15(1):12162.
Score: 0.043
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Structural basis of BAK sequestration by MCL-1 in apoptosis. Mol Cell. 2025 Apr 17; 85(8):1606-1623.e10.
Score: 0.043
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Conformational coupling between extracellular and transmembrane domains modulates holo-adhesion GPCR function. Nat Commun. 2024 12 04; 15(1):10545.
Score: 0.042
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The high- and low-affinity receptor binding sites of growth hormone are allosterically coupled. Proc Natl Acad Sci U S A. 2004 Dec 07; 101(49):17078-83.
Score: 0.042
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Structural and biophysical insights into targeting of claudin-4 by a synthetic antibody fragment. Commun Biol. 2024 06 17; 7(1):733.
Score: 0.041
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Dissecting the binding energy epitope of a high-affinity variant of human growth hormone: cooperative and additive effects from combining mutations from independently selected phage display mutagenesis libraries. Biochemistry. 2004 May 25; 43(20):6076-84.
Score: 0.040
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The structural basis for biological signaling, regulation, and specificity in the growth hormone-prolactin system of hormones and receptors. Adv Protein Chem. 2004; 68:147-69.
Score: 0.039
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Site2 binding energetics of the regulatory step of growth hormone-induced receptor homodimerization. Protein Sci. 2003 Sep; 12(9):1960-70.
Score: 0.038
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Determination of the energetics governing the regulatory step in growth hormone-induced receptor homodimerization. Proc Natl Acad Sci U S A. 2003 Feb 04; 100(3):952-7.
Score: 0.037
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Development, structure, and mechanism of synthetic antibodies that target claudin and Clostridium perfringens enterotoxin complexes. J Biol Chem. 2022 09; 298(9):102357.
Score: 0.036
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Structures of atypical chemokine receptor 3 reveal the basis for its promiscuity and signaling bias. Sci Adv. 2022 07 15; 8(28):eabn8063.
Score: 0.035
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Development of a universal nanobody-binding Fab module for fiducial-assisted cryo-EM studies of membrane proteins. Proc Natl Acad Sci U S A. 2021 11 23; 118(47).
Score: 0.034
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Recognition of an a-helical hairpin in P22 large terminase by a synthetic antibody fragment. Acta Crystallogr D Struct Biol. 2020 Sep 01; 76(Pt 9):876-888.
Score: 0.031
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Structure and mechanism of the ER-based glucosyltransferase ALG6. Nature. 2020 03; 579(7799):443-447.
Score: 0.030
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Structural basis for activation of SAGA histone acetyltransferase Gcn5 by partner subunit Ada2. Proc Natl Acad Sci U S A. 2018 10 02; 115(40):10010-10015.
Score: 0.027
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The structure of the C-terminal domain of the nucleoprotein from the Bundibugyo strain of the Ebola virus in complex with a pan-specific synthetic Fab. Acta Crystallogr D Struct Biol. 2018 07 01; 74(Pt 7):681-689.
Score: 0.027
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Crystallization and preliminary X-ray analysis of a 1:1 complex between a designed monomeric interferon-gamma and its soluble receptor. Protein Sci. 1998 Apr; 7(4):1057-60.
Score: 0.026
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Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme. Elife. 2018 03 29; 7.
Score: 0.026
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Structural basis for cytokine hormone-receptor recognition and receptor activation. Adv Protein Chem. 1998; 52:67-108.
Score: 0.026
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The Preserved HTH-Docking Cleft of HIV-1 Integrase Is Functionally Critical. Structure. 2016 11 01; 24(11):1936-1946.
Score: 0.024
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Specific Recognition of a Single-Stranded RNA Sequence by a Synthetic Antibody Fragment. J Mol Biol. 2016 10 09; 428(20):4100-4114.
Score: 0.024
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Architecture of the fungal nuclear pore inner ring complex. Science. 2015 Oct 02; 350(6256):56-64.
Score: 0.022
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Human-chromatin-related protein interactions identify a demethylase complex required for chromosome segregation. Cell Rep. 2014 Jul 10; 8(1):297-310.
Score: 0.020
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Structure of active ß-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide. Nature. 2013 May 02; 497(7447):137-41.
Score: 0.019
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Analysis of solvent structure in proteins using neutron D2O-H2O solvent maps: pattern of primary and secondary hydration of trypsin. Proteins. 1992 Mar; 12(3):223-36.
Score: 0.017
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Crystals of the complex between human growth hormone and the extracellular domain of its receptor. J Mol Biol. 1991 Dec 20; 222(4):865-8.
Score: 0.017
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Characterization of engineered actin binding proteins that control filament assembly and structure. PLoS One. 2010 Nov 12; 5(11):e13960.
Score: 0.016
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Crystal structure of full-length KcsA in its closed conformation. Proc Natl Acad Sci U S A. 2009 Apr 21; 106(16):6644-9.
Score: 0.014
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Exploring the capacity of minimalist protein interfaces: interface energetics and affinity maturation to picomolar KD of a single-domain antibody with a flat paratope. J Mol Biol. 2007 Nov 02; 373(4):941-53.
Score: 0.013
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Comprehensive and quantitative mapping of energy landscapes for protein-protein interactions by rapid combinatorial scanning. J Biol Chem. 2006 Aug 04; 281(31):22378-22385.
Score: 0.012
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Intramolecular cooperativity in a protein binding site assessed by combinatorial shotgun scanning mutagenesis. J Mol Biol. 2005 Apr 01; 347(3):489-94.
Score: 0.011
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Effect of protein packing structure on side-chain methyl rotor conformations. Nature. 1984 Oct 11-17; 311(5986):582-3.
Score: 0.010
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The functional binding epitope of a high affinity variant of human growth hormone mapped by shotgun alanine-scanning mutagenesis: insights into the mechanisms responsible for improved affinity. J Mol Biol. 2003 Sep 05; 332(1):195-204.
Score: 0.010
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Functional promiscuity of squirrel monkey growth hormone receptor toward both primate and nonprimate growth hormones. Mol Biol Evol. 2002 Jul; 19(7):1083-92.
Score: 0.009
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Probing intermolecular backbone H-bonding in serine proteinase-protein inhibitor complexes. Chem Biol. 1999 Jul; 6(7):419-27.
Score: 0.007
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Structure of bovine trypsinogen at 1.9 A resolution. Biochemistry. 1977 Feb 22; 16(4):654-64.
Score: 0.006
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Solvent structure in crystals of trypsin determined by X-ray and neutron diffraction. Proteins. 1992 Mar; 12(3):203-22.
Score: 0.004