"Protein Binding" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.
| Descriptor ID |
D011485
|
| MeSH Number(s) |
G02.111.679 G03.808
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Protein Binding".
Below are MeSH descriptors whose meaning is more specific than "Protein Binding".
This graph shows the total number of publications written about "Protein Binding" by people in this website by year, and whether "Protein Binding" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 14 | 14 |
| 1997 | 0 | 11 | 11 |
| 1998 | 0 | 14 | 14 |
| 1999 | 0 | 18 | 18 |
| 2000 | 0 | 32 | 32 |
| 2001 | 0 | 29 | 29 |
| 2002 | 0 | 50 | 50 |
| 2003 | 0 | 31 | 31 |
| 2004 | 0 | 50 | 50 |
| 2005 | 1 | 51 | 52 |
| 2006 | 0 | 35 | 35 |
| 2007 | 0 | 45 | 45 |
| 2008 | 1 | 39 | 40 |
| 2009 | 0 | 60 | 60 |
| 2010 | 0 | 59 | 59 |
| 2011 | 1 | 61 | 62 |
| 2012 | 0 | 57 | 57 |
| 2013 | 0 | 58 | 58 |
| 2014 | 0 | 57 | 57 |
| 2015 | 1 | 60 | 61 |
| 2016 | 0 | 54 | 54 |
| 2017 | 0 | 54 | 54 |
| 2018 | 0 | 49 | 49 |
| 2019 | 0 | 32 | 32 |
| 2020 | 0 | 38 | 38 |
| 2021 | 0 | 31 | 31 |
| 2022 | 0 | 15 | 15 |
| 2023 | 0 | 10 | 10 |
| 2024 | 4 | 13 | 17 |
| 2025 | 1 | 18 | 19 |
| 2026 | 0 | 10 | 10 |
To return to the timeline,
click here.
Below are the most recent publications written about "Protein Binding" by people in Profiles.
-
Promiscuous RNA binding by WDR5 remodels the KMT2A (MLL1) histone methyltransferase complex to an inactive state. Mol Cell. 2026 Sep 17; 86(18):3740-3758.e9.
-
Positional grammar of transcription factor binding partitions developmental and stress-response regulation in plants. Nat Commun. 2026 08 04; 17(1).
-
Epitope-guided Detection of a Molecular Glue-induced Ternary Complex Using Engineered Synthetic Antibody Fragments. J Mol Biol. 2026 Oct 01; 438(19):169953.
-
Structure of the Beat-Side complex reveals their interaction is required for neuromuscular system wiring. Cell Rep. 2026 Jul 28; 45(7):117661.
-
PANCS-spec-Binders: A system for rapidly discovering isoform- or epitope-specific binders. Proc Natl Acad Sci U S A. 2026 Jun 09; 123(23):e2531008123.
-
Selective fluorination of Fc glycans enhances antibody-mediated effector functions. Proc Natl Acad Sci U S A. 2026 Mar 24; 123(12):e2530653123.
-
Human GlyRa2 pore dynamics in gating and inhibition. Structure. 2026 May 07; 34(5):798-813.e7.
-
Toward universal binder discovery: Advances in display, computational design and in vivo platforms. Curr Opin Chem Biol. 2026 Jun; 92:102663.
-
The BK channel-NS1619 agonist complex reveals molecular insights into allosteric activation gating. Proc Natl Acad Sci U S A. 2026 Feb 03; 123(5):e2507707123.
-
A trans-synaptic IgLON adhesion molecular complex directly contacts and clusters a nicotinic receptor. Nat Commun. 2026 Jan 22; 17(1):1404.