"Protein Binding" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.
| Descriptor ID |
D011485
|
| MeSH Number(s) |
G02.111.679 G03.808
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Protein Binding".
Below are MeSH descriptors whose meaning is more specific than "Protein Binding".
This graph shows the total number of publications written about "Protein Binding" by people in this website by year, and whether "Protein Binding" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 14 | 14 |
| 1997 | 0 | 11 | 11 |
| 1998 | 0 | 15 | 15 |
| 1999 | 0 | 19 | 19 |
| 2000 | 0 | 34 | 34 |
| 2001 | 0 | 29 | 29 |
| 2002 | 0 | 51 | 51 |
| 2003 | 0 | 32 | 32 |
| 2004 | 0 | 49 | 49 |
| 2005 | 1 | 52 | 53 |
| 2006 | 0 | 35 | 35 |
| 2007 | 0 | 45 | 45 |
| 2008 | 1 | 41 | 42 |
| 2009 | 0 | 61 | 61 |
| 2010 | 0 | 61 | 61 |
| 2011 | 1 | 62 | 63 |
| 2012 | 0 | 56 | 56 |
| 2013 | 0 | 61 | 61 |
| 2014 | 0 | 57 | 57 |
| 2015 | 1 | 60 | 61 |
| 2016 | 0 | 55 | 55 |
| 2017 | 0 | 54 | 54 |
| 2018 | 0 | 49 | 49 |
| 2019 | 0 | 32 | 32 |
| 2020 | 0 | 38 | 38 |
| 2021 | 0 | 32 | 32 |
| 2022 | 0 | 14 | 14 |
| 2023 | 0 | 10 | 10 |
| 2024 | 4 | 13 | 17 |
| 2025 | 1 | 12 | 13 |
| 2026 | 0 | 1 | 1 |
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Below are the most recent publications written about "Protein Binding" by people in Profiles.
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A trans-synaptic IgLON adhesion molecular complex directly contacts and clusters a nicotinic receptor. Nat Commun. 2026 Jan 22; 17(1):1404.
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PANCS-Binders: a rapid, high-throughput binder discovery platform. Nat Methods. 2025 Aug; 22(8):1720-1730.
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Labeling of Cell Surface Proteins at the Drosophila Larval Neuromuscular Junction Using Binding Partner Peptides. Cold Spring Harb Protoc. 2025 Jul 01; 2025(7):pdb.prot108501.
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Structural basis and functional roles for Toll-like receptor binding to Latrophilin in C.?elegans development. Nat Struct Mol Biol. 2025 Sep; 32(9):1683-1696.
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Conformational dynamics and multimodal interaction of Paxillin with the focal adhesion targeting domain. Sci Adv. 2025 Jun 20; 11(25):eadt9936.
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Practical Tips for the Application of HDX-MS to Membrane Proteins, Biomolecular Condensates, and Weak Protein Binders. J Am Soc Mass Spectrom. 2025 Aug 06; 36(8):1575-1587.
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Effect of phosphorylation barcodes on arrestin binding to a chemokine receptor. Nature. 2025 Jul; 643(8070):280-287.
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Structural basis for nucleolin recognition of MYC promoter G-quadruplex. Science. 2025 04 18; 388(6744):eadr1752.
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Mapping the extracellular molecular architecture of the pAg-signaling complex with a-Butyrophilin antibodies. Sci Rep. 2025 Apr 09; 15(1):12162.
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Structural basis of BAK sequestration by MCL-1 in apoptosis. Mol Cell. 2025 Apr 17; 85(8):1606-1623.e10.