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Richard Whitley

Title
InstitutionUniversity of Chicago
AddressChicago IL 60637
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Shiraki K, Daikoku T, Prichard MN, Matsuo K, Okuda T, Yoshida Y, Takemoto M, Takeuchi K, Sada K, Whitley R, Kawana T. Vertical mother-to-infant transmission of herpes simplex virus 2 is correlated with tropism due to mutations in viral UL13. J Med Virol. 2024 Jan; 96(1):e29379. PMID: 38235617.
      Citations:    Fields:    Translation:HumansCellsPHPublic Health
    2. Whitley RJ, Hook EW. Shedding Patterns of Genital Herpes Simplex Virus Infections. JAMA. 2022 11 01; 328(17):1710-1711. PMID: 36272101.
      Citations: 1     Fields:    Translation:HumansCells
    3. Duffy C, Pridgen WL, Whitley RJ. Gastric herpes simplex virus type 1 infection is associated with functional gastrointestinal disorders in the presence and absence of comorbid fibromyalgia: a pilot case-control study. Infection. 2022 Oct; 50(5):1303-1311. PMID: 35445970; PMCID: PMC9522778.
      Citations: 2     Fields:    Translation:HumansCells
    4. Bernstock JD, Bag AK, Fiveash J, Kachurak K, Elsayed G, Chagoya G, Gessler F, Valdes PA, Madan-Swain A, Whitley R, Markert JM, Gillespie GY, Johnston JM, Friedman GK. Design and Rationale for First-in-Human Phase 1 Immunovirotherapy Clinical Trial of Oncolytic HSV G207 to Treat Malignant Pediatric Cerebellar Brain Tumors. Hum Gene Ther. 2020 10; 31(19-20):1132-1139. PMID: 32657154; PMCID: PMC7585605.
      Citations: 20     Fields:    Translation:HumansCellsCTClinical Trials
    5. Gnann JW, Agrawal A, Hart J, Buitrago M, Carson P, Hanfelt-Goade D, Tyler K, Spotkov J, Freifeld A, Moore T, Reyno J, Masur H, Jester P, Dale I, Li Y, Aban I, Lakeman FD, Whitley RJ, National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group. Lack of Efficacy of High-Titered Immunoglobulin in Patients with West Nile Virus Central Nervous System Disease. Emerg Infect Dis. 2019 11; 25(11):2064-2073. PMID: 31625835; PMCID: PMC6810207.
      Citations: 15     Fields:    Translation:HumansCells
    6. Totsch SK, Schlappi C, Kang KD, Ishizuka AS, Lynn GM, Fox B, Beierle EA, Whitley RJ, Markert JM, Gillespie GY, Bernstock JD, Friedman GK. Oncolytic herpes simplex virus immunotherapy for brain tumors: current pitfalls and emerging strategies to overcome therapeutic resistance. Oncogene. 2019 08; 38(34):6159-6171. PMID: 31289361; PMCID: PMC6771414.
      Citations: 31     Fields:    Translation:HumansCells
    7. Whitley RJ. Congenital Cytomegalovirus and Neonatal Herpes Simplex Virus Infections: To Treat or Not to Treat? Pediatr Infect Dis J. 2019 06; 38(6S Suppl 1):S60-S63. PMID: 31205247; PMCID: PMC6581200.
      Citations:    Fields:    Translation:Humans
    8. Akhtar LN, Bowen CD, Renner DW, Pandey U, Della Fera AN, Kimberlin DW, Prichard MN, Whitley RJ, Weitzman MD, Szpara ML. Genotypic and Phenotypic Diversity of Herpes Simplex Virus 2 within the Infected Neonatal Population. mSphere. 2019 02 27; 4(1). PMID: 30814317; PMCID: PMC6393728.
      Citations: 19     Fields:    Translation:HumansCells
    9. Whitley R, Baines J. Clinical management of herpes simplex virus infections: past, present, and future. F1000Res. 2018; 7. PMID: 30443341; PMCID: PMC6213787.
      Citations: 54     Fields:    Translation:HumansAnimals
    10. Gnann JW, Whitley RJ. Herpes Simplex Encephalitis: an Update. Curr Infect Dis Rep. 2017 Mar; 19(3):13. PMID: 28251511.
      Citations: 59     
    11. Nye S, Whitley RJ, Kong M. Viral Infection in the Development and Progression of Pediatric Acute Respiratory Distress Syndrome. Front Pediatr. 2016; 4:128. PMID: 27933286; PMCID: PMC5121220.
      Citations: 22     
    12. Gnann JW, Whitley RJ. Genital Herpes. N Engl J Med. 2016 11 10; 375(19):1906. PMID: 27959656.
      Citations: 2     Fields:    Translation:Humans
    13. Gnann JW, Whitley RJ. CLINICAL PRACTICE. Genital Herpes. N Engl J Med. 2016 Aug 18; 375(7):666-74. PMID: 27532832.
      Citations: 23     Fields:    Translation:HumansCellsPHPublic Health
    14. Everts M, Cihlar T, Bostwick JR, Whitley RJ. Accelerating Drug Development: Antiviral Therapies for Emerging Viruses as a Model. Annu Rev Pharmacol Toxicol. 2017 01 06; 57:155-169. PMID: 27483339.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    15. Everts M, Suto MJ, Painter GR, Whitley RJ. Consortia's critical role in developing medical countermeasures for re-emerging viral infections: a USA perspective. Future Virol. 2016 Mar; 11(3):187-195. PMID: 27325914; PMCID: PMC4912138.
      Citations: 1     
    16. Monto AS, Dobson J, Pocock S, Whitley RJ. Oseltamivir for influenza - Authors' reply. Lancet. 2016 Jan 09; 387(10014):125. PMID: 26841996.
      Citations:    Fields:    Translation:Humans
    17. Whitley RJ. Herpes Simplex Virus Infections of the Central Nervous System. Continuum (Minneap Minn). 2015 Dec; 21(6 Neuroinfectious Disease):1704-13. PMID: 26633784.
      Citations: 29     Fields:    Translation:HumansCells
    18. Kong MY, Whitley RJ, Peng N, Oster R, Schoeb TR, Sullender W, Ambalavanan N, Clancy JP, Gaggar A, Blalock JE. Addendum: Kong, M.Y.; Whitley, R.J.; Peng, N.; Oster, R.; Schoeb, T.R.; Sullender, W.; Ambalavanan, N.; Clancy, J.P.; Gaggar, A.; Blalock J.E. Matrix Metalloproteinase-9 Mediates RSV Infection in Vitro and in Vivo. Viruses 2015, 30, 7, 4230–4253. Viruses. 2015 Oct; 7(10):5609. PMID: 26702463; PMCID: PMC4632397.
      Citations: 4     Fields:    
    19. Monto AS, Dobson J, Pocock S, Whitley RJ. Oseltamivir for influenza - Authors' reply. Lancet. 2015 Sep 19; 386(9999):1135-6. PMID: 26461902.
      Citations: 2     Fields:    Translation:Humans
    20. Kong MY, Whitley RJ, Peng N, Oster R, Schoeb TR, Sullender W, Ambalavanan N, Clancy JP, Gaggar A, Blalock JE. Matrix Metalloproteinase-9 Mediates RSV Infection in Vitro and in Vivo. Viruses. 2015 Jul 30; 7(8):4230-53. PMID: 26264019; PMCID: PMC4576178.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    21. Gnann JW, Hart J, Aurelius E, Studahl M, Eriksson BM, Hanley D, Aoki F, Jackson AC, Griffiths P, Miedzinski L, Hanfelt-Goade D, Hinthorn D, Aksamit A, Cruz-Flores S, Dale I, Cloud G, Jester P, Whitley RJ, National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group, Sköldenberg B, Schliamser S, Ahlm C. Herpes Simplex Encephalitis: Lack of Clinical Benefit of Long-term Valacyclovir Therapy. Clin Infect Dis. 2015 Sep 01; 61(5):683-91. PMID: 25956891; PMCID: PMC4542890.
      Citations: 30     Fields:    Translation:Humans
    22. Abzug MJ, Michaels MG, Wald E, Jacobs RF, Wilson G, Krogstad P, Storch GA, Lawrence R, Shelton M, Palmer A, Robinson J, Dennehy P, Sood SK, Cloud G, Jester P, Acosta EP, Whitley R, Kimberlin D, National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group, Romero JR, Sánchez PJ. A Randomized, Double-Blind, Placebo-Controlled Trial of Pleconaril for the Treatment of Neonates With Enterovirus Sepsis. J Pediatric Infect Dis Soc. 2016 Mar; 5(1):53-62. PMID: 26407253; PMCID: PMC4765488.
      Citations: 43     Fields:    Translation:HumansCells
    23. DeVincenzo JP, Boeckh M, Bont L, Crowe JE, Griffiths P, Hayden FG, Hodinka RL, Smyth RL, Spencer K, Thirstrup S, Walsh EE, Whitley RJ, Simões EA. Challenges and opportunities in developing respiratory syncytial virus therapeutics. J Infect Dis. 2015 Mar 15; 211 Suppl 1:S1-S20. PMID: 25713060; PMCID: PMC4345819.
      Citations: 47     Fields:    Translation:HumansCells
    24. Kimberlin DW, Jester PM, Ahmed A, Arav-Boger R, Michaels MG, Ashouri N, Englund JA, Estrada B, Jacobs RF, Sood SK, Whitworth MS, Abzug MJ, Caserta MT, Fowler S, Lujan-Zilbermann J, Storch GA, DeBiasi RL, Han JY, Palmer A, Weiner LB, Bocchini JA, Dennehy PH, Finn A, Griffiths PD, Luck S, Gutierrez K, Halasa N, Homans J, Shane AL, Sharland M, Simonsen K, Vanchiere JA, Woods CR, Sabo DL, Aban I, Kuo H, James SH, Prichard MN, Griffin J, Giles D, Acosta EP, Whitley RJ, National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group, Sánchez PJ, Romero JR. Valganciclovir for symptomatic congenital cytomegalovirus disease. N Engl J Med. 2015 Mar 05; 372(10):933-43. PMID: 25738669; PMCID: PMC4401811.
      Citations: 176     Fields:    Translation:Humans
    25. Chow FC, Glaser CA, Sheriff H, Xia D, Messenger S, Whitley R, Venkatesan A. Use of clinical and neuroimaging characteristics to distinguish temporal lobe herpes simplex encephalitis from its mimics. Clin Infect Dis. 2015 May 01; 60(9):1377-83. PMID: 25637586; PMCID: PMC4462661.
      Citations: 47     Fields:    Translation:Humans
    26. Dobson J, Whitley RJ, Pocock S, Monto AS. Oseltamivir treatment for influenza in adults: a meta-analysis of randomised controlled trials. Lancet. 2015 May 02; 385(9979):1729-1737. PMID: 25640810.
      Citations: 209     Fields:    Translation:Humans
    27. Whitley RJ. Editorial commentary: Waning efficacy of the herpes zoster vaccine. Clin Infect Dis. 2015 Mar 15; 60(6):910-1. PMID: 25416752.
      Citations:    Fields:    Translation:Humans
    28. Prichard MN, Whitley RJ. The development of new therapies for human herpesvirus 6. Curr Opin Virol. 2014 Dec; 9:148-53. PMID: 25462447; PMCID: PMC4267975.
      Citations: 18     Fields:    Translation:Humans
    29. Whitley R, Laughlin A, Carson S, Mitha E, Tellier G, Stich M, Elder J, Alexander WJ, Dobo S, Collis P, Sheridan WP. Single dose peramivir for the treatment of acute seasonal influenza: integrated analysis of efficacy and safety from two placebo-controlled trials. Antivir Ther. 2015; 20(7):709-19. PMID: 25318121.
      Citations: 16     Fields:    Translation:HumansCells
    30. DeVincenzo JP, Whitley RJ, Mackman RL, Scaglioni-Weinlich C, Harrison L, Farrell E, McBride S, Lambkin-Williams R, Jordan R, Xin Y, Ramanathan S, O'Riordan T, Lewis SA, Li X, Toback SL, Lin SL, Chien JW. Oral GS-5806 activity in a respiratory syncytial virus challenge study. N Engl J Med. 2014 Aug 21; 371(8):711-22. PMID: 25140957.
      Citations: 155     Fields:    Translation:HumansCells
    31. Jackson JD, McMorris AM, Roth JC, Coleman JM, Whitley RJ, Gillespie GY, Carroll SL, Markert JM, Cassady KA. Assessment of oncolytic HSV efficacy following increased entry-receptor expression in malignant peripheral nerve sheath tumor cell lines. Gene Ther. 2014 Nov; 21(11):984-90. PMID: 25119379; PMCID: PMC5745010.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    32. Kamal MA, Acosta EP, Kimberlin DW, Gibiansky L, Jester P, Niranjan V, Clinch B, Ampofo K, Whitley R, Rayner CR, Rath B, Sánchez PJ. The posology of oseltamivir in infants with influenza infection using a population pharmacokinetic approach. Clin Pharmacol Ther. 2014 Sep; 96(3):380-9. PMID: 24865390.
      Citations: 10     Fields:    Translation:Humans
    33. Hart J, Tillman G, Kraut MA, Chiang HS, Strain JF, Li Y, Agrawal AG, Jester P, Gnann JW, Whitley RJ, NIAID Collaborative Antiviral Study Group West Nile Virus 210 Protocol Team. West Nile virus neuroinvasive disease: neurological manifestations and prospective longitudinal outcomes. BMC Infect Dis. 2014 May 09; 14:248. PMID: 24884681; PMCID: PMC4020876.
      Citations: 44     Fields:    Translation:HumansCells
    34. King L, Tulandi T, Whitley R, Constantinescu T, Ells C, Zelkowitz P. What's the message? A content analysis of newspaper articles about assisted reproductive technology from 2005 to 2011. Hum Fertil (Camb). 2014 Jun; 17(2):124-32. PMID: 24669833.
      Citations: 2     Fields:    Translation:Humans
    35. Roth JC, Cassady KA, Cody JJ, Parker JN, Price KH, Coleman JM, Peggins JO, Noker PE, Powers NW, Grimes SD, Carroll SL, Gillespie GY, Whitley RJ, Markert JM. Evaluation of the safety and biodistribution of M032, an attenuated herpes simplex virus type 1 expressing hIL-12, after intracerebral administration to aotus nonhuman primates. Hum Gene Ther Clin Dev. 2014 Mar; 25(1):16-27. PMID: 24649838; PMCID: PMC4047998.
      Citations: 44     Fields:    Translation:AnimalsCells
    36. Roth JC, Cassady KA, Cody JJ, Parker JN, Price KH, Coleman JM, Peggins JO, Noker PE, Powers N, Grimes S, Carroll SL, Gillespie GY, Whitley R, Markert J. Evaluation of the Safety and Biodistribution of M032, an Attenuated HSV-1 Virus Expressing hIL-12, After Intracerebral Administration to Aotus Non-Human Primates. Hum Gene Ther Clin Dev. 2014 Feb 28. PMID: 24579875.
      Citations:    
    37. Markert JM, Razdan SN, Kuo HC, Cantor A, Knoll A, Karrasch M, Nabors LB, Markiewicz M, Agee BS, Coleman JM, Lakeman AD, Palmer CA, Parker JN, Whitley RJ, Weichselbaum RR, Fiveash JB, Gillespie GY. A phase 1 trial of oncolytic HSV-1, G207, given in combination with radiation for recurrent GBM demonstrates safety and radiographic responses. Mol Ther. 2014 May; 22(5):1048-55. PMID: 24572293; PMCID: PMC4015243.
      Citations: 149     Fields:    Translation:HumansCellsCTClinical Trials
    38. Whitley RJ, Prichard M. A novel potential therapy for HSV. N Engl J Med. 2014 Jan 16; 370(3):273-4. PMID: 24428473.
      Citations: 3     Fields:    Translation:HumansCells
    39. Widener RW, Whitley RJ. Herpes simplex virus. Handb Clin Neurol. 2014; 123:251-63. PMID: 25015489.
      Citations: 26     Fields:    Translation:HumansCells
    40. Gaston DC, Odom CI, Li L, Markert JM, Roth JC, Cassady KA, Whitley RJ, Parker JN. Production of bioactive soluble interleukin-15 in complex with interleukin-15 receptor alpha from a conditionally-replicating oncolytic HSV-1. PLoS One. 2013; 8(11):e81768. PMID: 24312353; PMCID: PMC3842420.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    41. Venkatesan A, Tunkel AR, Bloch KC, Lauring AS, Sejvar J, Bitnun A, Stahl JP, Mailles A, Drebot M, Rupprecht CE, Yoder J, Cope JR, Wilson MR, Whitley RJ, Sullivan J, Granerod J, Jones C, Eastwood K, Ward KN, Durrheim DN, Solbrig MV, Guo-Dong L, Glaser CA, International Encephalitis Consortium. Case definitions, diagnostic algorithms, and priorities in encephalitis: consensus statement of the international encephalitis consortium. Clin Infect Dis. 2013 Oct; 57(8):1114-28. PMID: 23861361; PMCID: PMC3783060.
      Citations: 353     Fields:    Translation:Humans
    42. Whitley RJ, Markert JM. Viral therapy of glioblastoma multiforme. Proc Natl Acad Sci U S A. 2013 Jul 16; 110(29):11672-3. PMID: 23836634; PMCID: PMC3718094.
      Citations: 5     Fields:    Translation:AnimalsCells
    43. Whitley RJ, Boucher CA, Lina B, Nguyen-Van-Tam JS, Osterhaus A, Schutten M, Monto AS. Global assessment of resistance to neuraminidase inhibitors, 2008-2011: the Influenza Resistance Information Study (IRIS). Clin Infect Dis. 2013 May; 56(9):1197-205. PMID: 23307766.
      Citations: 38     Fields:    Translation:HumansAnimalsCells
    44. Roizman B, Whitley RJ. An inquiry into the molecular basis of HSV latency and reactivation. Annu Rev Microbiol. 2013; 67:355-74. PMID: 24024635.
      Citations: 112     Fields:    Translation:HumansAnimalsCells
    45. Kimberlin DW, Acosta EP, Prichard MN, Ampofo K, Lang D, Ashouri N, Vanchiere JA, Abzug MJ, Abughali N, Caserta MT, Englund JA, Sood SK, Spigarelli MG, Bradley JS, Lew J, Michaels MG, Wan W, Cloud G, Jester P, Lakeman FD, Whitley RJ, National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group, Sánchez PJ. Oseltamivir pharmacokinetics, dosing, and resistance among children aged <2 years with influenza. J Infect Dis. 2013 Mar 01; 207(5):709-20. PMID: 23230059; PMCID: PMC3563309.
      Citations: 15     Fields:    Translation:HumansCells
    46. Van Wagoner NJ, Brown E, Whitley R, Hook EW. Predictors of undiagnosed herpes simplex virus type 2 seropositivity among persons attending an HIV care clinic. Sex Transm Dis. 2012 Nov; 39(11):857-9. PMID: 23064534; PMCID: PMC3941199.
      Citations: 2     Fields:    Translation:HumansCellsPHPublic Health
    47. Whitley RJ. Changing epidemiology of herpes simplex virus infections. Clin Infect Dis. 2013 Feb; 56(3):352-3. PMID: 23087393.
      Citations: 7     Fields:    Translation:HumansCells
    48. Rha B, Redden D, Benfield M, Lakeman F, Whitley RJ, Shimamura M. Correlation and clinical utility of pp65 antigenemia and quantitative polymerase chain reaction assays for detection of cytomegalovirus in pediatric renal transplant patients. Pediatr Transplant. 2012 Sep; 16(6):627-37. PMID: 22694244; PMCID: PMC3461327.
      Citations: 4     Fields:    Translation:HumansCells
    49. Markert JM, Cody JJ, Parker JN, Coleman JM, Price KH, Kern ER, Quenelle DC, Lakeman AD, Schoeb TR, Palmer CA, Cartner SC, Gillespie GY, Whitley RJ. Preclinical evaluation of a genetically engineered herpes simplex virus expressing interleukin-12. J Virol. 2012 May; 86(9):5304-13. PMID: 22379082; PMCID: PMC3347348.
      Citations: 49     Fields:    Translation:HumansAnimalsCells
    50. Whitley RJ. The use of antiviral drugs during the neonatal period. Clin Perinatol. 2012 Mar; 39(1):69-81. PMID: 22341538; PMCID: PMC3290126.
      Citations: 11     Fields:    Translation:Humans
    51. Coen DM, Whitley RJ. Antiviral drugs and antiviral drug resistance. Curr Opin Virol. 2011 Dec; 1(6):545-7. PMID: 22440912; PMCID: PMC3433155.
      Citations: 8     Fields:    Translation:Humans
    52. Kimberlin DW, Whitley RJ, Wan W, Powell DA, Storch G, Ahmed A, Palmer A, Jacobs RF, Bradley JS, Robinson JL, Shelton M, Dennehy PH, Leach C, Rathore M, Abughali N, Wright P, Frenkel LM, Brady RC, Van Dyke R, Weiner LB, Guzman-Cottrill J, McCarthy CA, Griffin J, Jester P, Parker M, Lakeman FD, Kuo H, Lee CH, Cloud GA, National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group, Sánchez PJ. Oral acyclovir suppression and neurodevelopment after neonatal herpes. N Engl J Med. 2011 Oct 06; 365(14):1284-92. PMID: 21991950; PMCID: PMC3250992.
      Citations: 65     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
    53. McJunkin JE, Nahata MC, De Los Reyes EC, Hunt WG, Caceres M, Khan RR, Chebib MG, Taravath S, Minnich LL, Carr R, Welch CA, Whitley RJ. Safety and pharmacokinetics of ribavirin for the treatment of la crosse encephalitis. Pediatr Infect Dis J. 2011 Oct; 30(10):860-5. PMID: 21544005.
      Citations: 11     Fields:    Translation:HumansCellsCTClinical Trials
    54. Cunningham A, Griffiths P, Leone P, Mindel A, Patel R, Stanberry L, Whitley R. Current management and recommendations for access to antiviral therapy of herpes labialis. J Clin Virol. 2012 Jan; 53(1):6-11. PMID: 21889905; PMCID: PMC3423903.
      Citations: 11     Fields:    Translation:HumansCells
    55. Norberg P, Tyler S, Severini A, Whitley R, Liljeqvist JÅ, Bergström T. A genome-wide comparative evolutionary analysis of herpes simplex virus type 1 and varicella zoster virus. PLoS One. 2011; 6(7):e22527. PMID: 21799886; PMCID: PMC3143153.
      Citations: 42     Fields:    Translation:HumansCells
    56. Everts M, Knight WB, Harris DR, Secrist JA, Whitley RJ. The Alabama Drug Discovery Alliance: a collaborative partnership to facilitate academic drug discovery. Pharm Res. 2011 Jul; 28(7):1454-9. PMID: 21448756; PMCID: PMC3161513.
      Citations: 2     Fields:    
    57. Thompson C, Whitley R. Neonatal herpes simplex virus infections: where are we now? Adv Exp Med Biol. 2011; 697:221-30. PMID: 21120729; PMCID: PMC3433171.
      Citations: 23     Fields:    Translation:HumansCells
    58. Cardo D, Dennehy PH, Halverson P, Fishman N, Kohn M, Murphy CL, Whitley RJ, HAI Elimination White Paper Writing Group, Brennan PJ, Bright J, Curry C, Graham D, Haerum B, Kainer M, Kaye K, Lundstrom T, Richards C, Tomlinson L, Skillen EL, Streed S, Young M, Septimus E. Moving toward elimination of healthcare-associated infections: a call to action. Infect Control Hosp Epidemiol. 2010 Nov; 31(11):1101-5. PMID: 20929300.
      Citations: 14     Fields:    
    59. Cardo D, Dennehy PH, Halverson P, Fishman N, Kohn M, Murphy CL, Whitley RJ, HAI Elimination White Paper Writing Group. Moving toward elimination of healthcare-associated infections: a call to action. Am J Infect Control. 2010 Nov; 38(9):671-5. PMID: 21058460.
      Citations: 10     Fields:    Translation:HumansPHPublic Health
    60. James SH, Whitley RJ. Treatment of herpes simplex virus infections in pediatric patients: current status and future needs. Clin Pharmacol Ther. 2010 Nov; 88(5):720-4. PMID: 20881952; PMCID: PMC3685871.
      Citations: 9     Fields:    Translation:HumansCells
    61. Acosta EP, Jester P, Gal P, Wimmer J, Wade J, Whitley RJ, Kimberlin DW, National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group. Oseltamivir dosing for influenza infection in premature neonates. J Infect Dis. 2010 Aug 15; 202(4):563-6. PMID: 20594104; PMCID: PMC2904429.
      Citations: 24     Fields:    Translation:HumansCells
    62. Whitley RJ, Volpi A, McKendrick M, Wijck Av, Oaklander AL. Management of herpes zoster and post-herpetic neuralgia now and in the future. J Clin Virol. 2010 May; 48 Suppl 1:S20-8. PMID: 20510264.
      Citations: 29     Fields:    Translation:HumansCells
    63. Whitley RJ. Of ferrets and humans: influenza pathogenesis. J Infect Dis. 2010 Apr 01; 201(7):976-7. PMID: 20187748.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    64. Van Wagoner NJ, Geisler WM, Sizemore JM, Whitley R, Hook EW. Herpes simplex virus in African American heterosexual males: the roles of age and male circumcision. Sex Transm Dis. 2010 Apr; 37(4):217-22. PMID: 19910861.
      Citations: 3     Fields:    Translation:HumansCells
    65. Kimberlin DW, Shalabi M, Abzug MJ, Lang D, Jacobs RF, Storch G, Bradley JS, Wade KC, Ramilo O, Shelton M, Leach C, Guzman-Cottrill J, Robinson J, Abughali N, Englund J, Griffin J, Jester P, Cloud GA, Whitley RJ, NIAID Collaborative Antiviral Study Group, Romero JR. Safety of oseltamivir compared with the adamantanes in children less than 12 months of age. Pediatr Infect Dis J. 2010 Mar; 29(3):195-8. PMID: 19949363; PMCID: PMC3703844.
      Citations: 13     Fields:    Translation:Humans
    66. Whitley RJ. Incomplete financial disclosures in an editorial, clinical crossroads, and reply letter related to herpes zoster. JAMA. 2010 Feb 24; 303(8):733-4. PMID: 20103745.
      Citations:    Fields:    Translation:Humans
    67. Prichard MN, Quenelle DC, Hartline CB, Harden EA, Jefferson G, Frederick SL, Daily SL, Whitley RJ, Tiwari KN, Maddry JA, Secrist JA, Kern ER. Inhibition of herpesvirus replication by 5-substituted 4'-thiopyrimidine nucleosides. Antimicrob Agents Chemother. 2009 Dec; 53(12):5251-8. PMID: 19770274; PMCID: PMC2786333.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    68. Oliver SE, Cloud GA, Demmler GJ, Dankner W, Shelton M, Jacobs RF, Vaudry W, Pass RF, Soong SJ, Whitley RJ, Kimberlin DW, National Institute of Allergy, Infectious Diseases Collaborative Antiviral Study Group, Sánchez PJ. Neurodevelopmental outcomes following ganciclovir therapy in symptomatic congenital cytomegalovirus infections involving the central nervous system. J Clin Virol. 2009 Dec; 46 Suppl 4:S22-6. PMID: 19766534; PMCID: PMC2805252.
      Citations: 59     Fields:    Translation:HumansCTClinical Trials
    69. Whitley RJ. A 70-year-old woman with shingles: review of herpes zoster. JAMA. 2009 Jul 01; 302(1):73-80. PMID: 19491172.
      Citations: 14     Fields:    Translation:Humans
    70. James SH, Kimberlin DW, Whitley RJ. Antiviral therapy for herpesvirus central nervous system infections: neonatal herpes simplex virus infection, herpes simplex encephalitis, and congenital cytomegalovirus infection. Antiviral Res. 2009 Sep; 83(3):207-13. PMID: 19414035; PMCID: PMC2748655.
      Citations: 30     Fields:    Translation:Humans
    71. Nassetta L, Kimberlin D, Whitley R. Treatment of congenital cytomegalovirus infection: implications for future therapeutic strategies. J Antimicrob Chemother. 2009 May; 63(5):862-7. PMID: 19287011; PMCID: PMC2667137.
      Citations: 42     Fields:    Translation:Humans
    72. Whitley RJ, Gnann JW. Herpes zoster in the age of focused immunosuppressive therapy. JAMA. 2009 Feb 18; 301(7):774-5. PMID: 19224757.
      Citations: 4     Fields:    Translation:Humans
    73. Markert JM, Liechty PG, Wang W, Gaston S, Braz E, Karrasch M, Nabors LB, Markiewicz M, Lakeman AD, Palmer CA, Parker JN, Whitley RJ, Gillespie GY. Phase Ib trial of mutant herpes simplex virus G207 inoculated pre-and post-tumor resection for recurrent GBM. Mol Ther. 2009 Jan; 17(1):199-207. PMID: 18957964; PMCID: PMC2834981.
      Citations: 207     Fields:    Translation:HumansCellsCTClinical Trials
    74. Levitsky J, Duddempudi AT, Lakeman FD, Whitley RJ, Luby JP, Lee WM, Fontana RJ, Blei AT, Ison MG, US Acute Liver Failure Study Group. Detection and diagnosis of herpes simplex virus infection in adults with acute liver failure. Liver Transpl. 2008 Oct; 14(10):1498-504. PMID: 18825709; PMCID: PMC3618973.
      Citations: 30     Fields:    Translation:HumansCells
    75. Griffiths P, Whitley R, Snydman DR, Singh N, Boeckh M, International Herpes Management Forum. Contemporary management of cytomegalovirus infection in transplant recipients: guidelines from an IHMF workshop, 2007. Herpes. 2008 Oct; 15(1):4-12. PMID: 18983762.
      Citations: 10     Fields:    Translation:Humans
    76. Tunkel AR, Glaser CA, Bloch KC, Sejvar JJ, Marra CM, Roos KL, Hartman BJ, Kaplan SL, Scheld WM, Whitley RJ, Infectious Diseases Society of America. The management of encephalitis: clinical practice guidelines by the Infectious Diseases Society of America. Clin Infect Dis. 2008 Aug 01; 47(3):303-27. PMID: 18582201.
      Citations: 302     Fields:    Translation:Humans
    77. Monto AS, Whitley RJ. Seasonal and pandemic influenza: a 2007 update on challenges and solutions. Clin Infect Dis. 2008 Apr 01; 46(7):1024-31. PMID: 18444819.
      Citations: 11     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    78. Kimberlin DW, Acosta EP, Sood S, Agrawal V, Homans J, Jacobs RF, Lang D, Romero JR, Griffin J, Cloud GA, Lakeman FD, Whitley RJ, National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group, Sánchez PJ. Pharmacokinetic and pharmacodynamic assessment of oral valganciclovir in the treatment of symptomatic congenital cytomegalovirus disease. J Infect Dis. 2008 Mar 15; 197(6):836-45. PMID: 18279073.
      Citations: 61     Fields:    Translation:HumansCellsCTClinical Trials
    79. Whitley R. The new age of molecular diagnostics for microbial agents. N Engl J Med. 2008 Mar 06; 358(10):988-9. PMID: 18256386.
      Citations: 12     Fields:    Translation:HumansCells
    80. Gardella C, Handsfield HH, Whitley R. Neonatal herpes - the forgotten perinatal infection. Sex Transm Dis. 2008 Jan; 35(1):22-4. PMID: 18157063.
      Citations:    Fields:    Translation:HumansPHPublic Health
    81. Dworkin RH, Gnann JW, Oaklander AL, Raja SN, Schmader KE, Whitley RJ. Diagnosis and assessment of pain associated with herpes zoster and postherpetic neuralgia. J Pain. 2008 Jan; 9(1 Suppl 1):S37-44. PMID: 18166464.
      Citations: 70     Fields:    Translation:Humans
    82. Whitley RJ. Therapy of herpes virus infections in children. Adv Exp Med Biol. 2008; 609:216-32. PMID: 18193668.
      Citations: 4     Fields:    Translation:Humans
    83. Whitley RJ. The role of oseltamivir in the treatment and prevention of influenza in children. Expert Opin Drug Metab Toxicol. 2007 Oct; 3(5):755-67. PMID: 17916060.
      Citations: 6     Fields:    Translation:HumansPHPublic Health
    84. Whitley R, Davis EA, Suppapanya N. Incidence of neonatal herpes simplex virus infections in a managed-care population. Sex Transm Dis. 2007 Sep; 34(9):704-8. PMID: 17413535.
      Citations: 19     Fields:    Translation:HumansPHPublic Health
    85. Breuer J, Whitley R. Varicella zoster virus: natural history and current therapies of varicella and herpes zoster. Herpes. 2007 Sep; 14 Suppl 2:25-9. PMID: 17939892.
      Citations: 20     Fields:    Translation:HumansCells
    86. Whitley RJ, Gnann JW. The incidence and severity of herpes simplex encephalitis in Sweden, 1990-2001. Clin Infect Dis. 2007 Oct 01; 45(7):881-2. PMID: 17806054.
      Citations: 3     Fields:    Translation:HumansCells
    87. Parker SD, Rottinghaus ST, Zajac AJ, Yue L, Hunter E, Whitley RJ, Parker JN. HIV-1(89.6) Gag expressed from a replication competent HSV-1 vector elicits persistent cellular immune responses in mice. Vaccine. 2007 Sep 17; 25(37-38):6764-73. PMID: 17706843; PMCID: PMC2084203.
      Citations: 4     Fields:    Translation:AnimalsCellsPHPublic Health
    88. Patel R, Stanberry L, Whitley RJ. Review of recent HSV recurrent-infection treatment studies. Herpes. 2007 Jun; 14(1):23-6. PMID: 17848215.
      Citations:    Fields:    Translation:HumansCells
    89. Gilbert S, Corey L, Cunningham A, Malkin JE, Stanberry L, Whitley R, Spruance S. An update on short-course intermittent and prevention therapies for herpes labialis. Herpes. 2007 Jun; 14 Suppl 1:13A-18A. PMID: 17877887.
      Citations: 4     Fields:    Translation:HumansCellsPHPublic Health
    90. Rottinghaus ST, Whitley RJ. Current non-AIDS antiviral chemotherapy. Expert Rev Anti Infect Ther. 2007 Apr; 5(2):217-30. PMID: 17402837.
      Citations: 1     Fields:    Translation:HumansAnimals
    91. Kimberlin DW, Whitley RJ. Varicella-zoster vaccine for the prevention of herpes zoster. N Engl J Med. 2007 Mar 29; 356(13):1338-43. PMID: 17392303.
      Citations: 27     Fields:    Translation:HumansCells
    92. Acosta EP, Brundage RC, King JR, Sood S, Agrawal V, Homans J, Jacobs RF, Lang D, Romero JR, Griffin J, Cloud G, Whitley R, Kimberlin DW, National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group, Sánchez PJ. Ganciclovir population pharmacokinetics in neonates following intravenous administration of ganciclovir and oral administration of a liquid valganciclovir formulation. Clin Pharmacol Ther. 2007 Jun; 81(6):867-72. PMID: 17392728.
      Citations: 24     Fields:    Translation:HumansCTClinical Trials
    93. Dworkin RH, Johnson RW, Breuer J, Gnann JW, Levin MJ, Backonja M, Betts RF, Gershon AA, Haanpaa ML, McKendrick MW, Nurmikko TJ, Oaklander AL, Oxman MN, Pavan-Langston D, Petersen KL, Rowbotham MC, Schmader KE, Stacey BR, Tyring SK, van Wijck AJ, Wallace MS, Wassilew SW, Whitley RJ. Recommendations for the management of herpes zoster. Clin Infect Dis. 2007 Jan 01; 44 Suppl 1:S1-26. PMID: 17143845.
      Citations: 217     Fields:    Translation:HumansCells
    94. Spruance S, Aoki FY, Tyring S, Stanberry L, Whitley R, Hamed K. Short-course therapy for recurrent genital herpes and herpes labialis. J Fam Pract. 2007 Jan; 56(1):30-6. PMID: 17217895.
      Citations: 1     Fields:    Translation:HumansCellsPHPublic Health
    95. Boeckh M, Englund J, Li Y, Miller C, Cross A, Fernandez H, Kuypers J, Kim H, Gnann J, Whitley R, NIAID Collaborative Antiviral Study Group. Randomized controlled multicenter trial of aerosolized ribavirin for respiratory syncytial virus upper respiratory tract infection in hematopoietic cell transplant recipients. Clin Infect Dis. 2007 Jan 15; 44(2):245-9. PMID: 17173225.
      Citations: 57     Fields:    Translation:Humans
    96. Garcia-Sastre A, Whitley RJ. Lessons learned from reconstructing the 1918 influenza pandemic. J Infect Dis. 2006 Nov 01; 194 Suppl 2:S127-32. PMID: 17163385.
      Citations: 16     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    97. Whitley RJ, Bartlett J, Hayden FG, Pavia AT, Tapper M, Monto AS. Seasonal and pandemic influenza: recommendations for preparedness in the United States. J Infect Dis. 2006 Nov 01; 194 Suppl 2:S155-61. PMID: 17163389.
      Citations: 9     Fields:    Translation:HumansPHPublic Health
    98. Whitley RJ, Monto AS. Seasonal and pandemic influenza preparedness: a global threat. J Infect Dis. 2006 Nov 01; 194 Suppl 2:S65-9. PMID: 17163390.
      Citations: 11     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    99. Markert JM, Parker JN, Buchsbaum DJ, Grizzle WE, Gillespie GY, Whitley RJ. Oncolytic HSV-1 for the treatment of brain tumours. Herpes. 2006 Nov; 13(3):66-71. PMID: 17147910.
      Citations: 15     Fields:    Translation:HumansCells
    100. Whitley RJ, Monto AS. Prevention and treatment of influenza in high-risk groups: children, pregnant women, immunocompromised hosts, and nursing home residents. J Infect Dis. 2006 Nov 01; 194 Suppl 2:S133-8. PMID: 17163386.
      Citations: 42     Fields:    Translation:HumansAnimalsPHPublic Health
    101. Shalabi M, Whitley RJ. Recurrent benign lymphocytic meningitis. Clin Infect Dis. 2006 Nov 01; 43(9):1194-7. PMID: 17029141.
      Citations: 27     Fields:    Translation:HumansCells
    102. Guffey MB, Parker JN, Luckett WS, Gillespie GY, Meleth S, Whitley RJ, Markert JM. Engineered herpes simplex virus expressing bacterial cytosine deaminase for experimental therapy of brain tumors. Cancer Gene Ther. 2007 Jan; 14(1):45-56. PMID: 16990846.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    103. Whitley R. New approaches to the therapy of HSV infections. Herpes. 2006 Aug; 13(2):53-5. PMID: 16895657.
      Citations: 14     Fields:    Translation:Humans
    104. Shah AC, Price KH, Parker JN, Samuel SL, Meleth S, Cassady KA, Gillespie GY, Whitley RJ, Markert JM. Serial passage through human glioma xenografts selects for a Deltagamma134.5 herpes simplex virus type 1 mutant that exhibits decreased neurotoxicity and prolongs survival of mice with experimental brain tumors. J Virol. 2006 Aug; 80(15):7308-15. PMID: 16840311; PMCID: PMC1563698.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    105. Desmond RA, Accortt NA, Talley L, Villano SA, Soong SJ, Whitley RJ. Enteroviral meningitis: natural history and outcome of pleconaril therapy. Antimicrob Agents Chemother. 2006 Jul; 50(7):2409-14. PMID: 16801419; PMCID: PMC1489762.
      Citations: 32     Fields:    Translation:Humans
    106. Whitley R, Diaz-Mitoma F, Hamed K. Single-day famciclovir therapy for recurrent genital herpes. Curr Med Res Opin. 2006 Jul; 22(7):1307-10. PMID: 16834829.
      Citations: 1     Fields:    Translation:HumansCTClinical Trials
    107. Whitley RJ. Herpes simplex encephalitis: adolescents and adults. Antiviral Res. 2006 Sep; 71(2-3):141-8. PMID: 16675036.
      Citations: 168     Fields:    Translation:HumansCells
    108. Jester PM, Tilden SJ, Li Y, Whitley RJ, Sullender WM. Regulatory challenges: lessons from recent West Nile virus trials in the United States. Contemp Clin Trials. 2006 Jun; 27(3):254-9. PMID: 16603417.
      Citations: 8     Fields:    Translation:Humans
    109. Andrews WW, Kimberlin DF, Whitley R, Cliver S, Ramsey PS, Deeter R. Valacyclovir therapy to reduce recurrent genital herpes in pregnant women. Am J Obstet Gynecol. 2006 Mar; 194(3):774-81. PMID: 16522412.
      Citations: 16     Fields:    Translation:Humans
    110. Sizemore JM, Lakeman F, Whitley R, Hughes A, Hook EW. The spectrum of genital herpes simplex virus infection in men attending a sexually transmitted disease clinic. J Infect Dis. 2006 Apr 01; 193(7):905-11. PMID: 16518750.
      Citations: 5     Fields:    Translation:HumansCells
    111. Parker JN, Pfister LA, Quenelle D, Gillespie GY, Markert JM, Kern ER, Whitley RJ. Genetically engineered herpes simplex viruses that express IL-12 or GM-CSF as vaccine candidates. Vaccine. 2006 Mar 06; 24(10):1644-52. PMID: 16243413.
      Citations: 19     Fields:    Translation:AnimalsCells
    112. Handsfield HH, Waldo AB, Brown ZA, Corey L, Drucker JL, Ebel CW, Leone PA, Stanberry LR, Whitley RJ. Neonatal herpes should be a reportable disease. Sex Transm Dis. 2005 Sep; 32(9):521-5. PMID: 16118598.
      Citations: 4     Fields:    Translation:HumansCellsPHPublic Health
    113. Sizemore JM, Lakeman F, Whitley R, Hughes A, Hook EW. Historical correlates of genital herpes simplex virus type 2 infection in men attending an STD clinic. Sex Transm Infect. 2005 Aug; 81(4):303-5. PMID: 16061535; PMCID: PMC1745024.
      Citations: 1     Fields:    Translation:HumansCells
    114. Davis GL, Nelson DR, Terrault N, Pruett TL, Schiano TD, Fletcher CV, Sapan CV, Riser LN, Li Y, Whitley RJ, Gnann JW, Collaborative Antiviral Study Group. A randomized, open-label study to evaluate the safety and pharmacokinetics of human hepatitis C immune globulin (Civacir) in liver transplant recipients. Liver Transpl. 2005 Aug; 11(8):941-9. PMID: 16035063.
      Citations: 46     Fields:    Translation:HumansCells
    115. Hellums EK, Markert JM, Parker JN, He B, Perbal B, Roizman B, Whitley RJ, Langford CP, Bharara S, Gillespie GY. Increased efficacy of an interleukin-12-secreting herpes simplex virus in a syngeneic intracranial murine glioma model. Neuro Oncol. 2005 Jul; 7(3):213-24. PMID: 16053696; PMCID: PMC1871915.
      Citations: 73     Fields:    Translation:HumansAnimalsCells
    116. Whitley RJ. Changing dynamics of varicella-zoster virus infections in the 21st century: the impact of vaccination. J Infect Dis. 2005 Jun 15; 191(12):1999-2001. PMID: 15897983.
      Citations: 6     Fields:    Translation:Humans
    117. Parker JN, Meleth S, Hughes KB, Gillespie GY, Whitley RJ, Markert JM. Enhanced inhibition of syngeneic murine tumors by combinatorial therapy with genetically engineered HSV-1 expressing CCL2 and IL-12. Cancer Gene Ther. 2005 Apr; 12(4):359-68. PMID: 15678154.
      Citations: 34     Fields:    Translation:AnimalsCells
    118. Whitley RJ, Lakeman FD. Human herpesvirus 6 infection of the central nervous system: is it just a case of mistaken association? Clin Infect Dis. 2005 Mar 15; 40(6):894-5. PMID: 15736027.
      Citations: 5     Fields:    Translation:HumansCells
    119. Whitley RJ, Kimberlin DW. Herpes simplex encephalitis: children and adolescents. Semin Pediatr Infect Dis. 2005 Jan; 16(1):17-23. PMID: 15685145.
      Citations: 46     Fields:    Translation:HumansCells
    120. Kimberlin DW, Whitley RJ. Neonatal herpes: what have we learned. Semin Pediatr Infect Dis. 2005 Jan; 16(1):7-16. PMID: 15685144.
      Citations: 17     Fields:    Translation:HumansPHPublic Health
    121. Bradford RD, Cloud G, Lakeman AD, Boppana S, Kimberlin DW, Jacobs R, Demmler G, Sanchez P, Britt W, Soong SJ, Whitley RJ, National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group. Detection of cytomegalovirus (CMV) DNA by polymerase chain reaction is associated with hearing loss in newborns with symptomatic congenital CMV infection involving the central nervous system. J Infect Dis. 2005 Jan 15; 191(2):227-33. PMID: 15609232.
      Citations: 35     Fields:    Translation:HumansCells
    122. Mertz GJ, Miedzinski L, Goade D, Pavia AT, Hjelle B, Hansbarger CO, Levy H, Koster FT, Baum K, Lindemulder A, Wang W, Riser L, Fernandez H, Whitley RJ, Collaborative Antiviral Study Group. Placebo-controlled, double-blind trial of intravenous ribavirin for the treatment of hantavirus cardiopulmonary syndrome in North America. Clin Infect Dis. 2004 Nov 01; 39(9):1307-13. PMID: 15494907.
      Citations: 44     Fields:    Translation:Humans
    123. Tunkel AR, Hartman BJ, Kaplan SL, Kaufman BA, Roos KL, Scheld WM, Whitley RJ. Practice guidelines for the management of bacterial meningitis. Clin Infect Dis. 2004 Nov 01; 39(9):1267-84. PMID: 15494903.
      Citations: 496     Fields:    Translation:Humans
    124. Ch'ien LT, Cannon NJ, Charamella LJ, Dismukes WE, Whitley RJ, Buchanan RA, Alford CA. Effect of adenine arabinoside on severe Herpesvirus hominis infections in man. 1973. J Infect Dis. 2004 Oct 01; 190(7):1362-7. PMID: 15452921.
      Citations: 1     Fields:    Translation:Humans
    125. Whitley RJ. Commentary: Ch'ien LT, Cannon NJ, Charamella LJ, et al. effect of adenine arabinoside on severe herpesvirus hominis infections in man: preliminary report. J Infect Dis 1973; 128:658-63. J Infect Dis. 2004 Oct 01; 190(7):1360-7. PMID: 15346350.
      Citations:    Fields:    Translation:Humans
    126. Sacks SL, Griffiths PD, Corey L, Cohen C, Cunningham A, Dusheiko GM, Self S, Spruance S, Stanberry LR, Wald A, Whitley RJ. Lessons from HIV and hepatitis viruses. Antiviral Res. 2004 Aug; 63 Suppl 1:S11-8. PMID: 15450381.
      Citations:    Fields:    Translation:HumansCellsPHPublic Health
    127. Sacks SL, Griffiths PD, Corey L, Cohen C, Cunningham A, Dusheiko GM, Self S, Spruance S, Stanberry LR, Wald A, Whitley RJ. HSV-2 transmission. Antiviral Res. 2004 Aug; 63 Suppl 1:S27-35. PMID: 15450383.
      Citations: 18     Fields:    Translation:HumansCellsPHPublic Health
    128. Sacks SL, Griffiths PD, Corey L, Cohen C, Cunningham A, Dusheiko GM, Self S, Spruance S, Stanberry LR, Wald A, Whitley RJ. Introduction: Is viral shedding a surrogate marker for transmission of genital herpes? Antiviral Res. 2004 Aug; 63 Suppl 1:S3-9. PMID: 15450380.
      Citations: 6     Fields:    Translation:HumansCells
    129. Sacks SL, Griffiths PD, Corey L, Cohen C, Cunningham A, Dusheiko GM, Self S, Spruance S, Stanberry LR, Wald A, Whitley RJ. HSV shedding. Antiviral Res. 2004 Aug; 63 Suppl 1:S19-26. PMID: 15450382.
      Citations: 34     Fields:    Translation:HumansCells
    130. Whitley RJ. Cytomegalovirus and HIV: inextricably entwined pathogens. Lancet. 2004 Jun 26; 363(9427):2101-2. PMID: 15220028.
      Citations: 1     Fields:    Translation:HumansCells
    131. Whitley R. Neonatal herpes simplex virus infection. Curr Opin Infect Dis. 2004 Jun; 17(3):243-6. PMID: 15166828.
      Citations: 26     Fields:    Translation:HumansCellsPHPublic Health
    132. Whitley RJ. Congenital cytomegalovirus infection: epidemiology and treatment. Adv Exp Med Biol. 2004; 549:155-60. PMID: 15250528.
      Citations: 16     Fields:    Translation:HumansCells
    133. DeMets D, Califf R, Dixon D, Ellenberg S, Fleming T, Held P, Julian D, Kaplan R, Levine R, Neaton J, Packer M, Pocock S, Rockhold F, Seto B, Siegel J, Snapinn S, Stump D, Temple R, Whitley R. Issues in regulatory guidelines for data monitoring committees. Clin Trials. 2004; 1(2):162-9. PMID: 16281888.
      Citations: 8     Fields:    Translation:Humans
    134. Kimberlin DW, Lin CY, Demmler GJ, Dankner W, Shelton M, Jacobs RF, Vaudry W, Pass RF, Kiell JM, Soong SJ, Whitley RJ, National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group, Sánchez PJ. Effect of ganciclovir therapy on hearing in symptomatic congenital cytomegalovirus disease involving the central nervous system: a randomized, controlled trial. J Pediatr. 2003 Jul; 143(1):16-25. PMID: 12915819.
      Citations: 196     Fields:    Translation:HumansCTClinical Trials
    135. Abzug MJ, Cloud G, Bradley J, Powell D, Lepow M, Mani C, Capparelli EV, Blount S, Lakeman F, Whitley RJ, Kimberlin DW, National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group, Sánchez PJ, Romero J. Double blind placebo-controlled trial of pleconaril in infants with enterovirus meningitis. Pediatr Infect Dis J. 2003 Apr; 22(4):335-41. PMID: 12690273.
      Citations: 29     Fields:    Translation:HumansCTClinical Trials
    136. Whitley RJ. Smallpox: a potential agent of bioterrorism. Antiviral Res. 2003 Jan; 57(1-2):7-12. PMID: 12615298.
      Citations: 23     Fields:    Translation:HumansCellsPHPublic Health
    137. Advani SJ, Weichselbaum RR, Whitley RJ, Roizman B, Advani SJ, Weichselbaum RR, Whitley RJ, Roizman B. Friendly fire: redirecting herpes simplex virus-1 for therapeutic applications. Clin Microbiol Infect. 2002 Sep; 8(9):551-63. PMID: 12427216.
      Citations: 4     Fields:    Translation:HumansCells
    138. Gnann JW, Whitley RJ. Clinical practice. Herpes zoster. N Engl J Med. 2002 Aug 01; 347(5):340-6. PMID: 12151472.
      Citations: 175     Fields:    Translation:Humans
    139. Whitley RJ, Roizman B. Herpes simplex viruses: is a vaccine tenable? J Clin Invest. 2002 Jul; 110(2):145-51. PMID: 12122103; PMCID: PMC151069.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    140. Desmond RA, Weiss HL, Arani RB, Soong SJ, Wood MJ, Fiddian PA, Gnann JW, Whitley RJ, Desmond RA, Weiss HL, Arani RB, Soong SJ, Wood MJ, Fiddian PA, Gnann JW, Whitley RJ. Clinical applications for change-point analysis of herpes zoster pain. J Pain Symptom Manage. 2002 Jun; 23(6):510-6. PMID: 12067775.
      Citations: 12     Fields:    Translation:Humans
    141. Whitley RJ. Herpes Simplex Virus in Children. Curr Treat Options Neurol. 2002 May; 4(3):231-237. PMID: 11931730.
      Citations: 6     
    142. Whitley RJ, Gnann JW. Viral encephalitis: familiar infections and emerging pathogens. Lancet. 2002 Feb 09; 359(9305):507-13. PMID: 11853816.
      Citations: 131     Fields:    Translation:HumansAnimalsCells
    143. Chung SM, Advani SJ, Bradley JD, Kataoka Y, Vashistha K, Yan SY, Markert JM, Gillespie GY, Whitley RJ, Roizman B, Weichselbaum RR, Chung SM, Advani SJ, Bradley JD, Kataoka Y, Vashistha K, Yan SY, Markert JM, Gillespie GY, Whitley RJ, Roizman B, Weichselbaum RR. The use of a genetically engineered herpes simplex virus (R7020) with ionizing radiation for experimental hepatoma. Gene Ther. 2002 Jan; 9(1):75-80. PMID: 11850725.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    144. Whitley RJ. Herpes simplex virus infection. Semin Pediatr Infect Dis. 2002 Jan; 13(1):6-11. PMID: 12118847.
      Citations: 32     Fields:    Translation:HumansCells
    145. Abramson JS, Baker CJ, Fisher MC, Gerber MA, Meissner HC, Murray DL, Overturf GD, Prober CG, Rennels MB, Saari TN, Weiner LB, Whitley RJ, Pickering LK, AAP Committee on Infectious Diseases, 2000-2001. Prevention of hepatitis B in adolescents. Pediatrics. 2001 Dec; 108(6):1392. PMID: 11731676.
      Citations:    Fields:    Translation:Humans
    146. Arani RB, Soong SJ, Weiss HL, Wood MJ, Fiddian PA, Gnann JW, Whitley R, Arani RB, Soong SJ, Weiss HL, Wood MJ, Fiddian PA, Gnann JW, Whitley R. Phase specific analysis of herpes zoster associated pain data: a new statistical approach. Stat Med. 2001 Aug 30; 20(16):2429-39. PMID: 11512133.
      Citations: 19     Fields:    Translation:Humans
    147. Kimberlin DW, Lin CY, Jacobs RF, Powell DA, Corey L, Gruber WC, Rathore M, Bradley JS, Diaz PS, Kumar M, Arvin AM, Gutierrez K, Shelton M, Weiner LB, Sleasman JW, de Sierra TM, Weller S, Soong SJ, Kiell J, Lakeman FD, Whitley RJ, Kimberlin DW, Lin CY, Jacobs RF, Powell DA, Corey L, Gruber WC, Rathore M, Bradley JS, Diaz PS, Kumar M, Arvin AM, Gutierrez K, Shelton M, Weiner LB, Sleasman JW, de Sierra TM, Weller S, Soong SJ, Kiell J, Lakeman FD, Whitley RJ, National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group. Safety and efficacy of high-dose intravenous acyclovir in the management of neonatal herpes simplex virus infections. Pediatrics. 2001 Aug; 108(2):230-8. PMID: 11483782.
      Citations: 108     Fields:    Translation:HumansCTClinical Trials
    148. Kimberlin DW, Lin CY, Jacobs RF, Powell DA, Frenkel LM, Gruber WC, Rathore M, Bradley JS, Diaz PS, Kumar M, Arvin AM, Gutierrez K, Shelton M, Weiner LB, Sleasman JW, de Sierra TM, Soong SJ, Kiell J, Lakeman FD, Whitley RJ, Kimberlin DW, Lin CY, Jacobs RF, Powell DA, Frenkel LM, Gruber WC, Rathore M, Bradley JS, Diaz PS, Kumar M, Arvin AM, Gutierrez K, Shelton M, Weiner LB, Sleasman JW, de Sierra TM, Soong SJ, Kiell J, Lakeman FD, Whitley RJ, National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group. Natural history of neonatal herpes simplex virus infections in the acyclovir era. Pediatrics. 2001 Aug; 108(2):223-9. PMID: 11483781.
      Citations: 104     Fields:    Translation:HumansCells
    149. Whitley RJ, Roizman B. Herpes simplex virus infections. Lancet. 2001 May 12; 357(9267):1513-8. PMID: 11377626.
      Citations: 394     Fields:    Translation:HumansCells
    150. Markert JM, Parker JN, Gillespie GY, Whitley RJ. Genetically engineered human herpes simplex virus in the treatment of brain tumours. Herpes. 2001 Mar; 8(1):17-22. PMID: 11867012.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    151. Roizman B, Whitley RJ. The nine ages of herpes simplex virus. Herpes. 2001 Mar; 8(1):23-7. PMID: 11867013.
      Citations: 13     Fields:    Translation:HumansCells
    152. Whitley RJ, Hayden FG, Reisinger KS, Young N, Dutkowski R, Ipe D, Mills RG, Ward P. Oral oseltamivir treatment of influenza in children. Pediatr Infect Dis J. 2001 Feb; 20(2):127-33. PMID: 11224828.
      Citations: 206     Fields:    Translation:HumansCTClinical Trials
    153. Whitley RJ, Miller RL, Whitley RJ, Miller RL. Immunologic approach to herpes simplex virus. Viral Immunol. 2001; 14(2):111-8. PMID: 11398806.
      Citations: 9     Fields:    Translation:Humans
    154. Whitley RJ. Editorial: Our Evolving Knowledge of Herpesviruses. Herpes. 2000 Oct; 7(3):59. PMID: 11867003.
      Citations:    Fields:    
    155. Parker JN, Gillespie GY, Love CE, Randall S, Whitley RJ, Markert JM. Engineered herpes simplex virus expressing IL-12 in the treatment of experimental murine brain tumors. Proc Natl Acad Sci U S A. 2000 Feb 29; 97(5):2208-13. PMID: 10681459; PMCID: PMC15779.
      Citations: 137     Fields:    Translation:HumansAnimalsCells
    156. Markert JM, Gillespie GY, Weichselbaum RR, Roizman B, Whitley RJ. Genetically engineered HSV in the treatment of glioma: a review. Rev Med Virol. 2000 Jan-Feb; 10(1):17-30. PMID: 10654002.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    157. Whitley RJ, Gnann JW. Herpes zoster: focus on treatment in older adults. Antiviral Res. 1999 Dec 31; 44(3):145-54. PMID: 10651066.
      Citations: 2     Fields:    Translation:HumansCells
    158. Wintergerst U, Gangemi JD, Whitley RJ, Chatterjee S, Kern ER. Effect of recombinant human interferon alpha B/D (rHu-IFN-alpha B/D) in combination with acyclovir in experimental HSV-1 encephalitis. Antiviral Res. 1999 Nov; 44(1):75-8. PMID: 10588335.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    159. Rotbart HA, McCracken GH, Whitley RJ, Modlin JF, Cascino M, Shah S, Blum D. Clinical significance of enteroviruses in serious summer febrile illnesses of children. Pediatr Infect Dis J. 1999 Oct; 18(10):869-74. PMID: 10530582.
      Citations: 16     Fields:    Translation:HumansCells
    160. Abramson JS, Baker CJ, Fisher MC, Gerber MA, Meissner HC, Murray DL, Overturf GD, Prober CG, Rennels MB, Saari TN, Weiner LB, Whitley RJ. Possible association of intussusception with rotavirus vaccination. American Academy of Pediatrics. Committee on Infectious Diseases. Pediatrics. 1999 Sep; 104(3 Pt 1):575. PMID: 10469790.
      Citations: 6     Fields:    Translation:HumansCellsPHPublic Health
    161. Whitley RJ, Kimberlin DW. Viral encephalitis. Pediatr Rev. 1999 Jun; 20(6):192-8. PMID: 10352040.
      Citations: 7     Fields:    Translation:Humans
    162. Harrison RA, Soong S, Weiss HL, Gnann JW, Whitley RJ. A mixed model for factors predictive of pain in AIDS patients with herpes zoster. J Pain Symptom Manage. 1999 Jun; 17(6):410-7. PMID: 10388246.
      Citations:    Fields:    Translation:HumansCTClinical Trials
    163. Bradley JD, Kataoka Y, Advani S, Chung SM, Arani RB, Gillespie GY, Whitley RJ, Markert JM, Roizman B, Weichselbaum RR. Ionizing radiation improves survival in mice bearing intracranial high-grade gliomas injected with genetically modified herpes simplex virus. Clin Cancer Res. 1999 Jun; 5(6):1517-22. PMID: 10389941.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    164. Advani SJ, Chung SM, Yan SY, Gillespie GY, Markert JM, Whitley RJ, Roizman B, Weichselbaum RR. Replication-competent, nonneuroinvasive genetically engineered herpes virus is highly effective in the treatment of therapy-resistant experimental human tumors. Cancer Res. 1999 May 01; 59(9):2055-8. PMID: 10232586.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    165. Whitley RJ, Holland GN. Cytomegalovirus retinitis--evolving therapies in a new era. N Engl J Med. 1999 Apr 08; 340(14):1109-10. PMID: 10194243.
      Citations:    Fields:    Translation:Humans
    166. Martin DF, Dunn JP, Davis JL, Duker JS, Engstrom RE, Friedberg DN, Jaffe GJ, Kuppermann BD, Polis MA, Whitley RJ, Wolitz RA, Benson CA. Use of the ganciclovir implant for the treatment of cytomegalovirus retinitis in the era of potent antiretroviral therapy: recommendations of the International AIDS Society-USA panel. Am J Ophthalmol. 1999 Mar; 127(3):329-39. PMID: 10088745.
      Citations: 12     Fields:    Translation:Humans
    167. Whitley RJ, Gnann JW. Therapeutic approaches to the management of herpes zoster. Adv Exp Med Biol. 1999; 458:159-65. PMID: 10549388.
      Citations:    Fields:    Translation:Humans
    168. Whitley RJ. Approaches to the treatment of varicella-zoster virus infections. Contrib Microbiol. 1999; 3:158-72. PMID: 10599529.
      Citations: 2     Fields:    Translation:Humans
    169. Whitley RJ, Weiss HL, Soong SJ, Gnann JW. Herpes zoster: risk categories for persistent pain. J Infect Dis. 1999 Jan; 179(1):9-15. PMID: 9841816.
      Citations: 10     Fields:    Translation:HumansCTClinical Trials
    170. Yoshida M, Yamada M, Tsukazaki T, Chatterjee S, Lakeman FD, Nii S, Whitley RJ. Comparison of antiviral compounds against human herpesvirus 6 and 7. Antiviral Res. 1998 Dec; 40(1-2):73-84. PMID: 9864048.
      Citations: 20     Fields:    Translation:HumansCells
    171. Whitley RJ, Shukla S, Crooks RJ. The identification of risk factors associated with persistent pain following herpes zoster. J Infect Dis. 1998 Nov; 178 Suppl 1:S71-5. PMID: 9852979.
      Citations: 14     Fields:    Translation:Humans
    172. Kimberlin DW, Whitley RJ. Human herpesvirus-6: neurologic implications of a newly-described viral pathogen. J Neurovirol. 1998 Oct; 4(5):474-85. PMID: 9839645.
      Citations: 13     Fields:    Translation:HumansCells
    173. Kimberlin DF, Weller S, Whitley RJ, Andrews WW, Hauth JC, Lakeman F, Miller G. Pharmacokinetics of oral valacyclovir and acyclovir in late pregnancy. Am J Obstet Gynecol. 1998 Oct; 179(4):846-51. PMID: 9790357.
      Citations: 16     Fields:    Translation:HumansCellsCTClinical Trials
    174. Whitley R. Sexually transmitted diseases. Lancet. 1998 Aug 22; 352(9128):651. PMID: 9746048.
      Citations:    Fields:    Translation:HumansCells
    175. Lakeman FD, Mayo MS, Whitley RJ, Domingues RB. Application of competitive PCR to cerebrospinal fluid samples from patients with herpes simplex encephalitis. J Clin Microbiol. 1998 Aug; 36(8):2229-34. PMID: 9665997; PMCID: PMC105021.
      Citations: 32     Fields:    Translation:HumansCells
    176. Dunkel EC, Scheer DI, Zhu Q, Whitley RJ, Schaffer PA, Pavan-Langston D, Whitely RJ. Retraction: A rabbit model for human cytomeglovirus--induced chorioretinal disease (J Infect Dis 1993;168:336-44). J Infect Dis. 1998 Jun; 177(6):1778. PMID: 9634358.
      Citations:    Fields:    
    177. Whitley RJ, Jacobson MA, Friedberg DN, Holland GN, Jabs DA, Dieterich DT, Hardy WD, Polis MA, Deutsch TA, Feinberg J, Spector SA, Walmsley S, Drew WL, Powderly WG, Griffiths PD, Benson CA, Kessler HA. Guidelines for the treatment of cytomegalovirus diseases in patients with AIDS in the era of potent antiretroviral therapy: recommendations of an international panel. International AIDS Society-USA. Arch Intern Med. 1998 May 11; 158(9):957-69. PMID: 9588429.
      Citations: 37     Fields:    Translation:Humans
    178. Cohen Stuart JW, Boucher CA, Cooper DA, Galasso GJ, Richman DD, Thomas HC, Whitley RJ. Summary of the III International Consensus Symposium on Combined Antiviral Therapy. Antiviral Res. 1998 May; 38(2):75-93. PMID: 9707371.
      Citations: 3     Fields:    Translation:HumansCells
    179. Gnann JW, Crumpacker CS, Lalezari JP, Smith JA, Tyring SK, Baum KF, Borucki MJ, Joseph WP, Mertz GJ, Steigbigel RT, Cloud GA, Soong SJ, Sherrill LC, DeHertogh DA, Whitley RJ. Sorivudine versus acyclovir for treatment of dermatomal herpes zoster in human immunodeficiency virus-infected patients: results from a randomized, controlled clinical trial. Collaborative Antiviral Study Group/AIDS Clinical Trials Group, Herpes Zoster Study Group. Antimicrob Agents Chemother. 1998 May; 42(5):1139-45. PMID: 9593141; PMCID: PMC105759.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    180. Whitley RJ, Kimberlin DW, Roizman B. Herpes simplex viruses. Clin Infect Dis. 1998 Mar; 26(3):541-53; quiz 554-5. PMID: 9524821.
      Citations: 131     Fields:    Translation:HumansCells
    181. Smith SJ, Li Y, Whitley R, Marion MJ, Partilo S, Carney WP, Brandt-Rauf PW. Molecular epidemiology of p53 protein mutations in workers exposed to vinyl chloride. Am J Epidemiol. 1998 Feb 01; 147(3):302-8. PMID: 9482505.
      Citations: 15     Fields:    Translation:HumansPHPublic Health
    182. Andreansky S, He B, van Cott J, McGhee J, Markert JM, Gillespie GY, Roizman B, Whitley RJ. Treatment of intracranial gliomas in immunocompetent mice using herpes simplex viruses that express murine interleukins. Gene Ther. 1998 Jan; 5(1):121-30. PMID: 9536273.
      Citations: 67     Fields:    Translation:AnimalsCells
    183. Mennemeyer ST, Cyr LP, Whitley RJ. Antiviral therapy for neonatal herpes simplex virus: a cost-effectiveness analysis. Am J Manag Care. 1997 Oct; 3(10):1551-8. PMID: 10178461.
      Citations: 5     Fields:    Translation:Humans
    184. Whitley R, Castillo N, Hassett JM, Banyas J, Luchette FA. Early tracheostomal healing in rabbits with use of various tracheal incisions. Wound Repair Regen. 1997 Oct-Dec; 5(4):323-8. PMID: 16984442.
      Citations: 1     Fields:    
    185. Whitley RJ, Cloud G, Gruber W, Storch GA, Demmler GJ, Jacobs RF, Dankner W, Spector SA, Starr S, Pass RF, Stagno S, Britt WJ, Alford C, Soong S, Zhou XJ, Sherrill L, FitzGerald JM, Sommadossi JP. Ganciclovir treatment of symptomatic congenital cytomegalovirus infection: results of a phase II study. National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group. J Infect Dis. 1997 May; 175(5):1080-6. PMID: 9129069.
      Citations: 56     Fields:    Translation:HumansCellsCTClinical Trials
    186. Andreansky S, Soroceanu L, Flotte ER, Chou J, Markert JM, Gillespie GY, Roizman B, Whitley RJ. Evaluation of genetically engineered herpes simplex viruses as oncolytic agents for human malignant brain tumors. Cancer Res. 1997 Apr 15; 57(8):1502-9. PMID: 9108452.
      Citations: 48     Fields:    Translation:HumansAnimalsCells
    187. Rotbart HA, Ahmed A, Hickey S, Dagan R, McCracken GH, Whitley RJ, Modlin JF, Cascino M, O'Connell JF, Menegus MA, Blum D. Diagnosis of enterovirus infection by polymerase chain reaction of multiple specimen types. Pediatr Infect Dis J. 1997 Apr; 16(4):409-11. PMID: 9109145.
      Citations: 17     Fields:    Translation:HumansCells
    188. Whitley RJ, Kimberlin DW. Treatment of viral infections during pregnancy and the neonatal period. Clin Perinatol. 1997 Mar; 24(1):267-83. PMID: 9099514.
      Citations: 6     Fields:    Translation:HumansPHPublic Health
    189. Cassady KA, Whitley RJ. New therapeutic approaches to the alphaherpesvirus infections. J Antimicrob Chemother. 1997 Feb; 39(2):119-28. PMID: 9069530.
      Citations: 17     Fields:    Translation:HumansCells
    190. Dworkin RH, Carrington D, Cunningham A, Kost RG, Levin MJ, McKendrick MW, Oxman MN, Rentier B, Schmader KE, Tappeiner G, Wassilew SW, Whitley RJ. Assessment of pain in herpes zoster: lessons learned from antiviral trials. Antiviral Res. 1997 Jan; 33(2):73-85. PMID: 9021049.
      Citations: 10     Fields:    Translation:Humans
    191. Kimberlin DW, Lakeman FD, Arvin AM, Prober CG, Corey L, Powell DA, Burchett SK, Jacobs RF, Starr SE, Whitley RJ. Application of the polymerase chain reaction to the diagnosis and management of neonatal herpes simplex virus disease. National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group. J Infect Dis. 1996 Dec; 174(6):1162-7. PMID: 8940204.
      Citations: 40     Fields:    Translation:HumansCells
    192. van der Meer JT, Drew WL, Bowden RA, Galasso GJ, Griffiths PD, Jabs DA, Katlama C, Spector SA, Whitley RJ. Summary of the International Consensus Symposium on Advances in the Diagnosis, Treatment and Prophylaxis and Cytomegalovirus Infection. Antiviral Res. 1996 Nov; 32(3):119-40. PMID: 8955508.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    193. Andreansky SS, He B, Gillespie GY, Soroceanu L, Markert J, Chou J, Roizman B, Whitley RJ. The application of genetically engineered herpes simplex viruses to the treatment of experimental brain tumors. Proc Natl Acad Sci U S A. 1996 Oct 15; 93(21):11313-8. PMID: 8876132; PMCID: PMC38054.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    194. Whitley RJ. The past as prelude to the future: history, status, and future of antiviral drugs. Ann Pharmacother. 1996 Sep; 30(9):967-71. PMID: 8876858.
      Citations: 5     Fields:    Translation:Humans
    195. Whitley RJ, Weiss H, Gnann JW, Tyring S, Mertz GJ, Pappas PG, Schleupner CJ, Hayden F, Wolf J, Soong SJ. Acyclovir with and without prednisone for the treatment of herpes zoster. A randomized, placebo-controlled trial. The National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group. Ann Intern Med. 1996 Sep 01; 125(5):376-83. PMID: 8702088.
      Citations: 66     Fields:    Translation:HumansCTClinical Trials
    196. Zhou XJ, Gruber W, Demmler G, Jacobs R, Reuman P, Adler S, Shelton M, Pass R, Britt B, Trang JM, Whitley RJ, Sommadossi JP. Population pharmacokinetics of ganciclovir in newborns with congenital cytomegalovirus infections. NIAID Collaborative Antiviral Study Group. Antimicrob Agents Chemother. 1996 Sep; 40(9):2202-5. PMID: 8878608; PMCID: PMC163500.
      Citations: 13     Fields:    Translation:HumansCTClinical Trials
    197. Wintergerst U, Gangemi JD, Kern ER, Whitley RJ, Chatterjee S. Differential effect of recombinant human and mouse interferons on replication of herpes simplex virus type 1 in mouse cells. Antiviral Res. 1996 Aug; 32(1):27-34. PMID: 8863993.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    198. Whitley RJ. Advances in the management of herpesvirus infections. Introduction. Semin Dermatol. 1996 Jun; 15(2 Suppl 1):1-3. PMID: 8840409.
      Citations: 1     Fields:    Translation:Humans
    199. Whitley RJ. Drug discovery for human immunodeficiency virus infection: conquests and hurdles. J Antimicrob Chemother. 1996 May; 37 Suppl B:151-9. PMID: 8818837.
      Citations:    Fields:    Translation:Humans
    200. Yoshida M, Yamada M, Chatterjee S, Lakeman F, Nii S, Whitley RJ. A method for detection of HHV-6 antigens and its use for evaluating antiviral drugs. J Virol Methods. 1996 Apr 26; 58(1-2):137-43. PMID: 8783159.
      Citations: 2     Fields:    Translation:HumansCells
    201. Kimberlin D, Powell D, Gruber W, Diaz P, Arvin A, Kumar M, Jacobs R, Van Dyke R, Burchett S, Soong SJ, Lakeman A, Whitley R. Administration of oral acyclovir suppressive therapy after neonatal herpes simplex virus disease limited to the skin, eyes and mouth: results of a phase I/II trial. Pediatr Infect Dis J. 1996 Mar; 15(3):247-54. PMID: 8852914.
      Citations: 32     Fields:    Translation:HumansCellsCTClinical Trials
    202. Kimberlin DW, Whitley RJ. Antiviral resistance: mechanisms, clinical significance, and future implications. J Antimicrob Chemother. 1996 Mar; 37(3):403-21. PMID: 9182098.
      Citations: 12     Fields:    Translation:HumansCells
    203. Wood MJ, Kay R, Dworkin RH, Soong SJ, Whitley RJ. Oral acyclovir therapy accelerates pain resolution in patients with herpes zoster: a meta-analysis of placebo-controlled trials. Clin Infect Dis. 1996 Feb; 22(2):341-7. PMID: 8838194.
      Citations: 50     Fields:    Translation:Humans
    204. Whitley RJ, Gnann JW, Weiss HL, Soong SJ. Unique clinical trial design: combination acyclovir plus prednisone therapy of localized zoster in the normal host. Antiviral Res. 1996 Jan; 29(1):67-8. PMID: 8721549.
      Citations: 2     Fields:    Translation:Humans
    205. Whitley RJ. Sorivudine: a potent inhibitor of varicella zoster virus replication. Adv Exp Med Biol. 1996; 394:41-4. PMID: 8815706.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    206. Whitley RJ. Sorivudine: a promising drug for the treatment of varicella-zoster virus infection. Neurology. 1995 Dec; 45(12 Suppl 8):S73-5. PMID: 8545030.
      Citations: 3     Fields:    Translation:Humans
    207. DeMets DL, Fleming TR, Whitley RJ, Childress JF, Ellenberg SS, Foulkes M, Mayer KH, O'Fallon J, Pollard RB, Rahal JJ, et al. The data and safety monitoring board and acquired immune deficiency syndrome (AIDS) clinical trials. Control Clin Trials. 1995 Dec; 16(6):408-21. PMID: 8720018.
      Citations: 6     Fields:    Translation:Humans
    208. Whitley RJ, Gnann JW. Herpes zoster in patients with human immunodeficiency virus infection--an ever-expanding spectrum of disease. Clin Infect Dis. 1995 Oct; 21(4):989-90. PMID: 8645853.
      Citations: 3     Fields:    Translation:Humans
    209. McCullers JA, Lakeman FD, Whitley RJ. Human herpesvirus 6 is associated with focal encephalitis. Clin Infect Dis. 1995 Sep; 21(3):571-6. PMID: 8527546.
      Citations: 37     Fields:    Translation:HumansCells
    210. Stewart JA, Reef SE, Pellett PE, Corey L, Whitley RJ. Herpesvirus infections in persons infected with human immunodeficiency virus. Clin Infect Dis. 1995 Aug; 21 Suppl 1:S114-20. PMID: 8547499.
      Citations: 15     Fields:    Translation:Humans
    211. Kimberlin DW, Whitley RJ. Antiviral resistance--an emerging problem. Antiviral Res. 1995 Apr; 26(4):365-8. PMID: 7574540.
      Citations: 1     Fields:    Translation:Humans
    212. Kimberlin DW, Coen DM, Biron KK, Cohen JI, Lamb RA, McKinlay M, Emini EA, Whitley RJ. Molecular mechanisms of antiviral resistance. Antiviral Res. 1995 Apr; 26(4):369-401. PMID: 7574541.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    213. Kimberlin DW, Spector SA, Hill EL, Biron KK, Hay AJ, Mayers DL, Whitley RJ. Assays for antiviral drug resistance. Antiviral Res. 1995 Apr; 26(4):403-13. PMID: 7574542.
      Citations: 1     Fields:    Translation:HumansCells
    214. Kimberlin DW, Crumpacker CS, Straus SE, Biron KK, Drew WL, Hayden FG, McKinlay M, Richman DD, Whitley RJ. Antiviral resistance in clinical practice. Antiviral Res. 1995 Apr; 26(4):423-38. PMID: 7574544.
      Citations: 5     Fields:    Translation:HumansCells
    215. Kimberlin DW, Couch RB, Galasso GJ, Richman DD, Whitley RJ. Research initiatives in studies of antiviral resistance and consensus points and recommendations. Antiviral Res. 1995 Apr; 26(4):439-52. PMID: 7574545.
      Citations:    Fields:    
    216. Kimberlin DW, Kern ER, Sidwell RW, North TW, Whitley RJ. Models of antiviral resistance. Antiviral Res. 1995 Apr; 26(4):415-22. PMID: 7574543.
      Citations: 1     Fields:    Translation:Animals
    217. Lakeman FD, Whitley RJ. Diagnosis of herpes simplex encephalitis: application of polymerase chain reaction to cerebrospinal fluid from brain-biopsied patients and correlation with disease. National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group. J Infect Dis. 1995 Apr; 171(4):857-63. PMID: 7706811.
      Citations: 139     Fields:    Translation:HumansCells
    218. Chambers R, Gillespie GY, Soroceanu L, Andreansky S, Chatterjee S, Chou J, Roizman B, Whitley RJ. Comparison of genetically engineered herpes simplex viruses for the treatment of brain tumors in a scid mouse model of human malignant glioma. Proc Natl Acad Sci U S A. 1995 Feb 28; 92(5):1411-5. PMID: 7877992; PMCID: PMC42529.
      Citations: 49     Fields:    Translation:HumansAnimalsCells
    219. Whitley RJ, Lakeman F. Herpes simplex virus infections of the central nervous system: therapeutic and diagnostic considerations. Clin Infect Dis. 1995 Feb; 20(2):414-20. PMID: 7742450.
      Citations: 64     Fields:    Translation:Humans
    220. Gangopadhyay NN, Whitley RJ, Chatterjee S. A rapid protein A binding radioimmunoassay for the evaluation of antiviral agents. J Virol Methods. 1994 Jul; 48(2-3):273-9. PMID: 7527404.
      Citations:    Fields:    Translation:HumansCells
    221. Whitley RJ. Neonatal herpes simplex virus infections: is there a role for immunoglobulin in disease prevention and therapy? Pediatr Infect Dis J. 1994 May; 13(5):432-8; discussion 438-9. PMID: 8072834.
      Citations: 12     Fields:    Translation:Humans
    222. Whitley RJ. Herpes simplex virus infections of women and their offspring: implications for a developed society. Proc Natl Acad Sci U S A. 1994 Mar 29; 91(7):2441-7. PMID: 8146137; PMCID: PMC43386.
      Citations: 16     Fields:    Translation:Humans
    223. Whitley RJ. Prospects for vaccination against herpes simplex virus. Pediatr Ann. 1993 Dec; 22(12):726, 729-32. PMID: 8139874.
      Citations: 3     Fields:    Translation:HumansCellsPHPublic Health
    224. Saag MS, Emini EA, Laskin OL, Douglas J, Lapidus WI, Schleif WA, Whitley RJ, Hildebrand C, Byrnes VW, Kappes JC, et al. A short-term clinical evaluation of L-697,661, a non-nucleoside inhibitor of HIV-1 reverse transcriptase. L-697,661 Working Group. N Engl J Med. 1993 Oct 07; 329(15):1065-72. PMID: 7690462.
      Citations: 39     Fields:    Translation:HumansCellsCTClinical Trials
    225. Norrby SR, Whitley RJ. Evaluation of new anti-infective drugs for the treatment of infection with human immunodeficiency virus. The European Working Party of the European Society of Clinical Microbiology and Infectious Diseases. Clin Infect Dis. 1993 Oct; 17(4):794-801. PMID: 8268368.
      Citations:    Fields:    Translation:Humans
    226. Dunkel EC, de Freitas D, Scheer DI, Siegel ML, Zhu Q, Whitley RJ, Schaffer PA, Pavan-Langston D. A rabbit model for human cytomegalovirus-induced chorioretinal disease. J Infect Dis. 1993 Aug; 168(2):336-44. PMID: 8393056.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    227. Mena W, Royal S, Pass RF, Whitley RJ, Philips JB. Diabetes insipidus associated with symptomatic congenital cytomegalovirus infection. J Pediatr. 1993 Jun; 122(6):911-3. PMID: 8388948.
      Citations: 7     Fields:    Translation:Humans
    228. Whitley RJ, Kern ER, Chatterjee S, Chou J, Roizman B. Replication, establishment of latency, and induced reactivation of herpes simplex virus gamma 1 34.5 deletion mutants in rodent models. J Clin Invest. 1993 Jun; 91(6):2837-43. PMID: 8390490; PMCID: PMC443352.
      Citations: 86     Fields:    Translation:AnimalsCells
    229. Sarkar S, Koga J, Whitley RJ, Chatterjee S. Antiviral effect of the extract of culture medium of Lentinus edodes mycelia on the replication of herpes simplex virus type 1. Antiviral Res. 1993 Apr; 20(4):293-303. PMID: 8387258.
      Citations: 8     Fields:    Translation:AnimalsCells
    230. Whitley RJ. Neonatal herpes simplex virus infections. J Med Virol. 1993; Suppl 1:13-21. PMID: 8245879.
      Citations: 16     Fields:    Translation:Humans
    231. Whitley RJ. Antiviral therapy: the time has come. J Med Virol. 1993; Suppl 1:1. PMID: 8245872.
      Citations:    Fields:    Translation:Humans
    232. Prober CG, Corey L, Brown ZA, Hensleigh PA, Frenkel LM, Bryson YJ, Whitley RJ, Arvin AM. The management of pregnancies complicated by genital infections with herpes simplex virus. Clin Infect Dis. 1992 Dec; 15(6):1031-8. PMID: 1457634.
      Citations: 24     Fields:    Translation:Humans
    233. McCracken GH, Sande MA, Lentnek A, Whitley RJ, Scheld WM. Evaluation of new anti-infective drugs for the treatment of acute bacterial meningitis. Infectious Diseases Society of America and the Food and Drug Administration. Clin Infect Dis. 1992 Nov; 15 Suppl 1:S182-8. PMID: 1477228.
      Citations: 1     Fields:    Translation:Humans
    234. Lentnek A, Sande MA, Whitley RJ, McCracken GH, Scheld WM. Evaluation of new anti-infective drugs for the treatment of cryptococcal meningitis. Infectious Diseases Society of America and the Food and Drug Administration. Clin Infect Dis. 1992 Nov; 15 Suppl 1:S189-94. PMID: 1477229.
      Citations:    Fields:    Translation:Humans
    235. Whitley RJ, Lentnek A, McCracken GH, Sande MA, Scheld WM. Evaluation of new anti-infective drugs for the treatment of viral encephalitis. Infectious Diseases Society of America and the Food and Drug Administration. Clin Infect Dis. 1992 Nov; 15 Suppl 1:S195-9. PMID: 1477230.
      Citations: 1     Fields:    Translation:Humans
    236. Sande MA, Whitley RJ, McCracken GH, Lentnek A, Scheld WM. Evaluation of new anti-infective drugs for the treatment of toxoplasma encephalitis. Infectious Diseases Society of America and the Food and Drug Administration. Clin Infect Dis. 1992 Nov; 15 Suppl 1:S200-5. PMID: 1477231.
      Citations: 1     Fields:    Translation:Humans
    237. Perl TM, Haugen TH, Pfaller MA, Hollis R, Lakeman AD, Whitley RJ, Nicholson D, Hunter GA, Wenzel RP. Transmission of herpes simplex virus type 1 infection in an intensive care unit. Ann Intern Med. 1992 Oct 01; 117(7):584-6. PMID: 1524332.
      Citations: 4     Fields:    Translation:Humans
    238. Whitley RJ, Gnann JW. Acyclovir: a decade later. N Engl J Med. 1992 Sep 10; 327(11):782-9. PMID: 1288525.
      Citations: 63     Fields:    Translation:Humans
    239. Chatterjee S, Burns P, Whitley RJ, Kern ER. Effect of (S)-1-[(3-hydroxy-2-phosphonyl methoxy) propyl] cytosine on the replication and morphogenesis of herpes simplex virus type 1. Antiviral Res. 1992 Sep; 19(3):181-92. PMID: 1332603.
      Citations:    Fields:    Translation:AnimalsCells
    240. Whitley RJ. Neonatal herpes simplex virus infections: pathogenesis and therapy. Pathol Biol (Paris). 1992 Sep; 40(7):729-34. PMID: 1336158.
      Citations: 3     Fields:    Translation:HumansCellsCTClinical Trials
    241. Whitley RJ. Therapeutic approaches to varicella-zoster virus infections. J Infect Dis. 1992 Aug; 166 Suppl 1:S51-7. PMID: 1378081.
      Citations: 10     Fields:    Translation:Humans
    242. Balfour HH, Rotbart HA, Feldman S, Dunkle LM, Feder HM, Prober CG, Hayden GF, Steinberg S, Whitley RJ, Goldberg L, et al. Acyclovir treatment of varicella in otherwise healthy adolescents. The Collaborative Acyclovir Varicella Study Group. J Pediatr. 1992 Apr; 120(4 Pt 1):627-33. PMID: 1313098.
      Citations: 13     Fields:    Translation:HumansCellsCTClinical Trials
    243. Whitley RJ, Gnann JW, Hinthorn D, Liu C, Pollard RB, Hayden F, Mertz GJ, Oxman M, Soong SJ. Disseminated herpes zoster in the immunocompromised host: a comparative trial of acyclovir and vidarabine. The NIAID Collaborative Antiviral Study Group. J Infect Dis. 1992 Mar; 165(3):450-5. PMID: 1538151.
      Citations: 19     Fields:    Translation:HumansCTClinical Trials
    244. Rodu B, Tate AL, Lakeman AF, Mattingly G, Russell CM, Whitley RJ. Prevalence of herpes simplex virus antibodies in dental students. J Dent Educ. 1992 Mar; 56(3):206-8. PMID: 1315348.
      Citations:    Fields:    Translation:HumansCells
    245. Whitley RJ, Meignier B. Herpes simplex vaccines. Biotechnology. 1992; 20:223-54. PMID: 1318135.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    246. Nielsen LN, Whitley RJ, Chatterjee S. Apical expression of herpes simplex virus type 2 glycoproteins in human neuroblastoma cells. Virology. 1991 Dec; 185(2):908-10. PMID: 1660208.
      Citations: 1     Fields:    Translation:Cells
    247. Schmid DS, Whittington W, Brown D, Reeves WC, Chatterjee S, Whitley RJ, Pellett PE, Sánchez-Martínez D. Evaluation of a test based on baculovirus-expressed glycoprotein G for detection of herpes simplex virus type-specific antibodies. J Infect Dis. 1991 Dec; 164(6):1196-9. PMID: 1659601.
      Citations: 13     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    248. Dunkle LM, Arvin AM, Whitley RJ, Rotbart HA, Feder HM, Feldman S, Gershon AA, Levy ML, Hayden GF, McGuirt PV, et al. A controlled trial of acyclovir for chickenpox in normal children. N Engl J Med. 1991 Nov 28; 325(22):1539-44. PMID: 1944438.
      Citations: 40     Fields:    Translation:HumansCTClinical Trials
    249. Whitley RJ. Herpes simplex virus infections of the central nervous system. Encephalitis and neonatal herpes. Drugs. 1991 Sep; 42(3):406-27. PMID: 1720381.
      Citations: 20     Fields:    Translation:Humans
    250. Saag MS, Crain MJ, Decker WD, Campbell-Hill S, Robinson S, Brown WE, Leuther M, Whitley RJ, Hahn BH, Shaw GM. High-level viremia in adults and children infected with human immunodeficiency virus: relation to disease stage and CD4+ lymphocyte levels. J Infect Dis. 1991 Jul; 164(1):72-80. PMID: 1676046.
      Citations: 34     Fields:    Translation:HumansCells
    251. Gnann JW, Whitley RJ. Natural history and treatment of varicella-zoster in high-risk populations. J Hosp Infect. 1991 Jun; 18 Suppl A:317-29. PMID: 1679798.
      Citations: 7     Fields:    Translation:Humans
    252. Co MS, Deschamps M, Whitley RJ, Queen C. Humanized antibodies for antiviral therapy. Proc Natl Acad Sci U S A. 1991 Apr 01; 88(7):2869-73. PMID: 1849279; PMCID: PMC51341.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    253. Whitley R, Arvin A, Prober C, Burchett S, Corey L, Powell D, Plotkin S, Starr S, Alford C, Connor J, et al. A controlled trial comparing vidarabine with acyclovir in neonatal herpes simplex virus infection. Infectious Diseases Collaborative Antiviral Study Group. N Engl J Med. 1991 Feb 14; 324(7):444-9. PMID: 1988829.
      Citations: 66     Fields:    Translation:HumansCTClinical Trials
    254. Whitley R, Arvin A, Prober C, Corey L, Burchett S, Plotkin S, Starr S, Jacobs R, Powell D, Nahmias A, et al. Predictors of morbidity and mortality in neonates with herpes simplex virus infections. The National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group. N Engl J Med. 1991 Feb 14; 324(7):450-4. PMID: 1988830.
      Citations: 79     Fields:    Translation:Humans
    255. Soong SJ, Watson NE, Caddell GR, Alford CA, Whitley RJ. Use of brain biopsy for diagnostic evaluation of patients with suspected herpes simplex encephalitis: a statistical model and its clinical implications. NIAID Collaborative Antiviral Study Group. J Infect Dis. 1991 Jan; 163(1):17-22. PMID: 1984464.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    256. Chou J, Kern ER, Whitley RJ, Roizman B. Mapping of herpes simplex virus-1 neurovirulence to gamma 134.5, a gene nonessential for growth in culture. Science. 1990 Nov 30; 250(4985):1262-6. PMID: 2173860.
      Citations: 330     Fields:    Translation:HumansAnimalsCells
    257. Martin B, Whitley RJ, Roizman B, Meignier B. In vivo behavior of genetically engineered herpes simplex viruses R7017 and R7020. II. Studies in immunocompetent and immunosuppressed owl monkeys (Aotus trivirgatus). J Infect Dis. 1990 Aug; 162(2):313-21. PMID: 2165104.
      Citations: 31     Fields:    Translation:AnimalsCells
    258. Whitley RJ. Viral encephalitis. N Engl J Med. 1990 Jul 26; 323(4):242-50. PMID: 2195341.
      Citations: 88     Fields:    Translation:Humans
    259. Gordon B, Selnes OA, Hart J, Hanley DF, Whitley RJ. Long-term cognitive sequelae of acyclovir-treated herpes simplex encephalitis. Arch Neurol. 1990 Jun; 47(6):646-7. PMID: 2346392.
      Citations: 29     Fields:    Translation:Humans
    260. Whitley RJ. Chickenpox: where do we stand with treatment? J Pediatr. 1990 Apr; 116(4):587. PMID: 2319406.
      Citations:    Fields:    Translation:Humans
    261. Chatterjee S, Nishimuro S, Whitley RJ. Expression of HSV-1 glycoproteins in tunicamycin-treated monkey kidney cells. Biochem Biophys Res Commun. 1990 Mar 30; 167(3):1139-45. PMID: 2157426.
      Citations: 2     Fields:    Translation:AnimalsCells
    262. Whitley RJ. Reference values in pediatric medicine. Mayo Clin Proc. 1990 Mar; 65(3):431-5. PMID: 2314124.
      Citations:    Fields:    Translation:Humans
    263. Rowley AH, Whitley RJ, Lakeman FD, Wolinsky SM. Rapid detection of herpes-simplex-virus DNA in cerebrospinal fluid of patients with herpes simplex encephalitis. Lancet. 1990 Feb 24; 335(8687):440-1. PMID: 1968171.
      Citations: 60     Fields:    Translation:HumansCells
    264. Canessa A, Chatterjee S, Whitley RJ, Prasthofer EF, Grossi CE, Tilden AB. Individual NK cell clones lyse both tumor cell targets and herpes simplex virus-infected fibroblasts in the absence of interferon. Viral Immunol. 1990; 3(3):217-24. PMID: 1701642.
      Citations: 1     Fields:    Translation:HumansCells
    265. Whitley RJ, Middlebrooks M, Gnann JW. Acyclovir: the past ten years. Adv Exp Med Biol. 1990; 278:243-53. PMID: 1963040.
      Citations: 1     Fields:    Translation:Humans
    266. Whitley RJ, Connell J, Markiewicz MA, Sommadossi JP. Novel pharmacological strategies in the treatment of life-threatening cytomegalovirus infections. Clinical experience with continuous infusion 9-(1,3-dihydroxy-2-propoxymethyl) guanine. Ann N Y Acad Sci. 1990; 616:452-60. PMID: 1964031.
      Citations:    Fields:    Translation:Humans
    267. Whitley RJ. Varicella-zoster virus infections: chronic disease in the immunocompromised host: evidence for persistent excretion of virus. Pediatr Infect Dis J. 1989 Sep; 8(9):584-5. PMID: 2552389.
      Citations: 1     Fields:    Translation:HumansCells
    268. Chatterjee S, Koga J, Whitley RJ. A role for herpes simplex virus type 1 glycoprotein E in induction of cell fusion. J Gen Virol. 1989 Aug; 70 ( Pt 8):2157-62. PMID: 2549184.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    269. Whitley RJ, Cobbs CG, Alford CA, Soong SJ, Hirsch MS, Connor JD, Corey L, Hanley DF, Levin M, Powell DA. Diseases that mimic herpes simplex encephalitis. Diagnosis, presentation, and outcome. NIAD Collaborative Antiviral Study Group. JAMA. 1989 Jul 14; 262(2):234-9. PMID: 2544743.
      Citations: 44     Fields:    Translation:HumansCells
    270. Cauda R, Laghi V, Tumbarello M, Ortona L, Whitley RJ. Immunological alterations associated with recurrent herpes simplex genitalis. Clin Immunol Immunopathol. 1989 May; 51(2):294-302. PMID: 2539283.
      Citations: 4     Fields:    Translation:HumansCells
    271. Baldwin S, Whitley RJ. Intrauterine herpes simplex virus infection. Teratology. 1989 Jan; 39(1):1-10. PMID: 2655150.
      Citations: 18     Fields:    Translation:Humans
    272. Chatterjee S, Whitley RJ. Effect of recombinant hybrid human interferon on replication and morphogenesis of HSV-1 in monkey cells. Virus Res. 1989 Jan; 12(1):33-41. PMID: 2541580.
      Citations: 4     Fields:    Translation:AnimalsCells
    273. Whitley RJ. Neonatal herpes simplex virus infections. Clin Perinatol. 1988 Dec; 15(4):903-16. PMID: 3061706.
      Citations: 6     Fields:    Translation:Humans
    274. Kahlon J, Whitley RJ. Antibody response of the newborn after herpes simplex virus infection. J Infect Dis. 1988 Nov; 158(5):925-33. PMID: 2846711.
      Citations: 11     Fields:    Translation:HumansCells
    275. Peacock JE, Kaplowitz LG, Sparling PF, Durack DT, Gnann JW, Whitley RJ, Lovett M, Bryson YJ, Klein RJ, Friedman-Kien AE, et al. Intravenous acyclovir therapy of first episodes of genital herpes: a multicenter double-blind, placebo-controlled trial. Am J Med. 1988 Sep; 85(3):301-6. PMID: 3046350.
      Citations: 5     Fields:    Translation:HumansCTClinical Trials
    276. Whitley RJ. Herpes simplex virus infections of the central nervous system. A review. Am J Med. 1988 Aug 29; 85(2A):61-7. PMID: 3044095.
      Citations: 12     Fields:    Translation:HumansCTClinical Trials
    277. Grimaldi LM, Roos RP, Manservigi R, Spear PG, Lakeman FD, Whitley RJ. An isoelectric focusing study in herpes simplex virus encephalitis. Ann Neurol. 1988 Aug; 24(2):227-32. PMID: 3140713.
      Citations: 3     Fields:    Translation:Humans
    278. Whitley RJ, Corey L, Arvin A, Lakeman FD, Sumaya CV, Wright PF, Dunkle LM, Steele RW, Soong SJ, Nahmias AJ, et al. Changing presentation of herpes simplex virus infection in neonates. J Infect Dis. 1988 Jul; 158(1):109-16. PMID: 3392410.
      Citations: 48     Fields:    Translation:HumansCTClinical Trials
    279. Reichman RC, Oakes D, Bonnez W, Greisberger C, Tyring S, Miller L, Whitley R, Carveth H, Weidner M, Krueger G, et al. Treatment of condyloma acuminatum with three different interferons administered intralesionally. A double-blind, placebo-controlled trial. Ann Intern Med. 1988 May; 108(5):675-9. PMID: 3358568.
      Citations: 15     Fields:    Translation:HumansCTClinical Trials
    280. Baldwin S, Stagno S, Odrezin GT, Kelly DR, Whitley RJ. Isolated Cryptococcus neoformans osteomyelitis in an immunocompetent child. Pediatr Infect Dis J. 1988 Apr; 7(4):289-92. PMID: 3368272.
      Citations: 5     Fields:    Translation:Humans
    281. Bell DS, Clements RS, Cutter GR, Whitley RJ. Condylomata acuminata in IDDM. Diabetes Care. 1988 Mar; 11(3):295-6. PMID: 3416688.
      Citations: 1     Fields:    Translation:Humans
    282. Whitley RJ. Ganciclovir--have we established clinical value in the treatment of cytomegalovirus infections? Ann Intern Med. 1988 Mar; 108(3):452-4. PMID: 2829680.
      Citations: 4     Fields:    Translation:HumansCTClinical Trials
    283. Whitley RJ. The frustrations of treating herpes simplex virus infections of the central nervous system. JAMA. 1988 Feb 19; 259(7):1067. PMID: 3339805.
      Citations: 2     Fields:    Translation:Humans
    284. Schlitt M, Bucher AP, Stroop WG, Pindak F, Bastian FO, Jennings RA, Lakeman AD, Whitley RJ. Neurovirulence in an experimental focal herpes encephalitis: relationship to observed seizures. Brain Res. 1988 Feb 09; 440(2):293-8. PMID: 2833994.
      Citations: 4     Fields:    Translation:AnimalsCells
    285. Whitley RJ. Natural history and pathogenesis of neonatal herpes simplex virus infections. Ann N Y Acad Sci. 1988; 549:103-17. PMID: 3067635.
      Citations:    Fields:    Translation:Humans
    286. Whitley RJ. Antiviral treatment of a serious herpes simplex infection: encephalitis. J Am Acad Dermatol. 1988 Jan; 18(1 Pt 2):209-11. PMID: 3339144.
      Citations: 4     Fields:    Translation:Humans
    287. Corey L, Whitley RJ, Stone EF, Mohan K. Difference between herpes simplex virus type 1 and type 2 neonatal encephalitis in neurological outcome. Lancet. 1988 Jan 2-9; 1(8575-6):1-4. PMID: 2891886.
      Citations: 64     Fields:    Translation:HumansCTClinical Trials
    288. Metcalf JF, Chatterjee S, Koga J, Whitley RJ. Protection against herpetic ocular disease by immunotherapy with monoclonal antibodies to herpes simplex virus glycoproteins. Intervirology. 1988; 29(1):39-49. PMID: 2838428.
      Citations: 9     Fields:    Translation:AnimalsCells
    289. Hanley DF, Johnson RT, Whitley RJ. Yes, brain biopsy should be a prerequisite for herpes simplex encephalitis treatment. Arch Neurol. 1987 Dec; 44(12):1289-90. PMID: 3675261.
      Citations: 12     Fields:    Translation:Humans
    290. Cauda R, Prasthofer EF, Grossi CE, Whitley RJ, Pass RF. Congenital cytomegalovirus: immunological alterations. J Med Virol. 1987 Sep; 23(1):41-9. PMID: 2824678.
      Citations: 3     Fields:    Translation:HumansCells
    291. Tyring SK, Cauda R, Baron S, Whitley RJ. Condyloma acuminatum: epidemiological, clinical and therapeutic aspects. Eur J Epidemiol. 1987 Sep; 3(3):209-15. PMID: 3308509.
      Citations: 2     Fields:    Translation:Humans
    292. Petty BG, Whitley RJ, Liao S, Krasny HC, Rocco LE, Davis LG, Lietman PS. Pharmacokinetics and tolerance of desciclovir, a prodrug of acyclovir, in healthy human volunteers. Antimicrob Agents Chemother. 1987 Sep; 31(9):1317-22. PMID: 3674844; PMCID: PMC174934.
      Citations: 4     Fields:    Translation:Humans
    293. Cauda R, Tyring SK, Grossi CE, Tilden AB, Hatch KD, Sams WM, Baron S, Whitley RJ. Patients with condyloma acuminatum exhibit decreased interleukin-2 and interferon gamma production and depressed natural killer activity. J Clin Immunol. 1987 Jul; 7(4):304-11. PMID: 3112173.
      Citations: 8     Fields:    Translation:HumansCells
    294. Baldwin S, Stagno S, Whitley R. Transfusion-associated viral infections. Curr Probl Pediatr. 1987 Jul; 17(7):391-443. PMID: 2824131.
      Citations:    Fields:    Translation:HumansCells
    295. Lakeman FD, Koga J, Whitley RJ. Detection of antigen to herpes simplex virus in cerebrospinal fluid from patients with herpes simplex encephalitis. J Infect Dis. 1987 Jun; 155(6):1172-8. PMID: 3033092.
      Citations: 10     Fields:    Translation:HumansCells
    296. Longnecker R, Chatterjee S, Whitley RJ, Roizman B. Identification of a herpes simplex virus 1 glycoprotein gene within a gene cluster dispensable for growth in cell culture. Proc Natl Acad Sci U S A. 1987 Jun; 84(12):4303-7. PMID: 3035578; PMCID: PMC305073.
      Citations: 62     Fields:    Translation:HumansAnimalsCells
    297. Cauda R, Grossi CE, Whitley RJ, Tilden AB. Analysis of immune function in herpes zoster patients: demonstration and characterization of suppressor cells. J Immunol. 1987 Feb 15; 138(4):1229-33. PMID: 3027175.
      Citations: 7     Fields:    Translation:HumansCells
    298. Barnes DW, Whitley RJ. Antiviral therapy and pulmonary disease. Chest. 1987 Feb; 91(2):246-51. PMID: 3026739.
      Citations:    Fields:    Translation:Humans
    299. Metcalf JF, Whitley RJ. Protective immunity against herpetic ocular disease in an outbred mouse model. Curr Eye Res. 1987 Jan; 6(1):167-71. PMID: 3030641.
      Citations: 3     Fields:    Translation:AnimalsCells
    300. Brasfield DM, Stagno S, Whitley RJ, Cloud G, Cassell G, Tiller RE. Infant pneumonitis associated with cytomegalovirus, Chlamydia, Pneumocystis, and Ureaplasma: follow-up. Pediatrics. 1987 Jan; 79(1):76-83. PMID: 3025807.
      Citations: 13     Fields:    Translation:HumansCells
    301. Whitley RJ. Approaches to therapy of viral infections. Adv Pediatr. 1987; 34:89-110. PMID: 2825477.
      Citations:    Fields:    Translation:HumansCells
    302. Whitley RJ, Hutto SC. Therapy of viral infections in children. Adv Pediatr Infect Dis. 1987; 2:35-56. PMID: 2840931.
      Citations:    Fields:    Translation:Humans
    303. Cauda R, Prasthofer EF, Tilden AB, Whitley RJ, Grossi CE. T-cell imbalances and NK activity in varicella-zoster virus infections. Viral Immunol. 1987; 1(2):145-52. PMID: 2978454.
      Citations: 6     Fields:    Translation:HumansCells
    304. Kahlon J, Chatterjee S, Lakeman FD, Lee F, Nahmias AJ, Whitley RJ. Detection of antibodies to herpes simplex virus in the cerebrospinal fluid of patients with herpes simplex encephalitis. J Infect Dis. 1987 Jan; 155(1):38-44. PMID: 3025307.
      Citations: 15     Fields:    Translation:HumansCells
    305. Metcalf JF, Koga J, Chatterjee S, Whitley RJ. Passive immunization with monoclonal antibodies against herpes simplex virus glycoproteins protects mice against herpetic ocular disease. Curr Eye Res. 1987 Jan; 6(1):173-7. PMID: 3030642.
      Citations: 18     Fields:    Translation:AnimalsCells
    306. Whitley RJ, Alford CA, Hirsch MS, Schooley RT, Luby JP, Aoki FY, Hanley D, Nahmias AJ, Soong SJ. Factors indicative of outcome in a comparative trial of acyclovir and vidarabine for biopsy-proven herpes simplex encephalitis. Infection. 1987; 15 Suppl 1:S3-8. PMID: 3298070.
      Citations: 9     Fields:    Translation:HumansCTClinical Trials
    307. Koga J, Chatterjee S, Whitley RJ. Studies on herpes simplex virus type 1 glycoproteins using monoclonal antibodies. Virology. 1986 Jun; 151(2):385-9. PMID: 3010559.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    308. Tilden AB, Cauda R, Grossi CE, Balch CM, Lakeman AD, Whitley RJ. Demonstration of NK cell-mediated lysis of varicella-zoster virus (VZV)-infected cells: characterization of the effector cells. J Immunol. 1986 Jun 01; 136(11):4243-8. PMID: 3009620.
      Citations: 10     Fields:    Translation:HumansCells
    309. Cauda R, Chatterjee S, Tilden AB, Grossi CE, Whitley RJ. Replication of varicella zoster virus in Raji cells. Virus Res. 1986 Jun; 4(4):337-42. PMID: 3014780.
      Citations: 1     Fields:    Translation:HumansCells
    310. Whitley RJ. Neonatal herpes simplex virus infections. Presentation and management. J Reprod Med. 1986 May; 31(5 Suppl):426-32. PMID: 3522894.
      Citations: 1     Fields:    Translation:HumansCTClinical Trials
    311. Lakeman AD, Nahmias AJ, Whitley RJ. Analysis of DNA from recurrent genital herpes simplex virus isolates by restriction endonuclease digestion. Sex Transm Dis. 1986 Apr-Jun; 13(2):61-6. PMID: 3012807.
      Citations: 8     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    312. Schlitt M, Lakeman AD, Wilson ER, To A, Acoff RW, Harsh GR, Whitley RJ. A rabbit model of focal herpes simplex encephalitis. J Infect Dis. 1986 Apr; 153(4):732-5. PMID: 3005433.
      Citations: 8     Fields:    Translation:AnimalsCells
    313. Kahlon J, Lakeman FD, Ackermann M, Whitley RJ. Human antibody response to herpes simplex virus-specific polypeptides after primary and recurrent infection. J Clin Microbiol. 1986 Apr; 23(4):725-30. PMID: 2422204; PMCID: PMC362825.
      Citations: 9     Fields:    Translation:HumansCells
    314. Barnes DW, Whitley RJ. CNS diseases associated with varicella zoster virus and herpes simplex virus infection. Pathogenesis and current therapy. Neurol Clin. 1986 Feb; 4(1):265-83. PMID: 3523204.
      Citations: 21     Fields:    Translation:Humans
    315. Whitley RJ, Alford CA, Hirsch MS, Schooley RT, Luby JP, Aoki FY, Hanley D, Nahmias AJ, Soong SJ. Vidarabine versus acyclovir therapy in herpes simplex encephalitis. N Engl J Med. 1986 Jan 16; 314(3):144-9. PMID: 3001520.
      Citations: 193     Fields:    Translation:HumansCellsCTClinical Trials
    316. Whitley RJ. Herpesvirus infections in the immunocompromised host: diagnosis and management. Adv Exp Med Biol. 1986; 202:95-118. PMID: 3024455.
      Citations:    Fields:    Translation:Humans
    317. Schlitt MJ, Morawetz RB, Bonnin JM, Zeiger HE, Whitley RJ. Brain biopsy for encephalitis. Clin Neurosurg. 1986; 33:591-602. PMID: 3539442.
      Citations:    Fields:    Translation:Humans
    318. Stagno S, Whitley RJ. Herpesvirus infections of pregnancy. Part II: Herpes simplex virus and varicella-zoster virus infections. N Engl J Med. 1985 Nov 21; 313(21):1327-30. PMID: 3903503.
      Citations: 17     Fields:    Translation:Humans
    319. Stagno S, Whitley RJ. Herpesvirus infections of pregnancy. Part I: Cytomegalovirus and Epstein-Barr virus infections. N Engl J Med. 1985 Nov 14; 313(20):1270-4. PMID: 2997607.
      Citations: 41     Fields:    Translation:HumansCells
    320. Schlitt M, Lakeman FD, Whitley RJ. Psychosis and herpes simplex encephalitis. South Med J. 1985 Nov; 78(11):1347-50. PMID: 4071143.
      Citations: 8     Fields:    Translation:Humans
    321. Chatterjee S, Hunter E, Whitley R. Effect of cloned human interferons on protein synthesis and morphogenesis of herpes simplex virus. J Virol. 1985 Nov; 56(2):419-25. PMID: 2997465; PMCID: PMC252595.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    322. McCann WP, Hall LM, Siler W, Barton N, Whitley RJ. High-pressure liquid chromatographic methods for determining arabinosyladenine-5'-monophosphate, arabinosyladenine, and arabinosylhypoxanthine in plasma and urine. Antimicrob Agents Chemother. 1985 Aug; 28(2):265-73. PMID: 2423028; PMCID: PMC180230.
      Citations: 7     Fields:    Translation:Humans
    323. Whitley RJ. Parvovirus infection: chance and investigation. N Engl J Med. 1985 Jul 11; 313(2):111-2. PMID: 2987694.
      Citations:    Fields:    Translation:Humans
    324. Whitley RJ. Therapy for human herpesvirus infections. A perspective. Ala J Med Sci. 1985 Apr; 22(2):193-207. PMID: 2988359.
      Citations:    Fields:    Translation:HumansCTClinical Trials
    325. Whitley RJ, Soong SJ, Alford CA, Hirsch MS, Schooley R, Oxman MN, Connor JD, Betts R, Dolin R, Reichman RC. Design of therapeutic studies in herpes simplex encephalitis. Lancet. 1985 Feb 02; 1(8423):284-5. PMID: 2857352.
      Citations: 3     Fields:    Translation:HumansCTClinical Trials
    326. Whitley RJ, Nahmias AJ. Therapeutic challenges of neonatal herpes simplex virus infection. Scand J Infect Dis Suppl. 1985; 47:97-106. PMID: 3868027.
      Citations: 1     Fields:    Translation:Humans
    327. Garcia JH, Sekar BC, Whitley RJ. Medical pathology conference. Headache, fever, abnormal behavior, and dysphasia in an elderly man. Ala J Med Sci. 1984 Oct; 21(4):399-406. PMID: 6507801.
      Citations:    Fields:    Translation:Humans
    328. Whitley RJ, Levin M, Barton N, Hershey BJ, Davis G, Keeney RE, Whelchel J, Diethelm AG, Kartus P, Soong SJ. Infections caused by herpes simplex virus in the immunocompromised host: natural history and topical acyclovir therapy. J Infect Dis. 1984 Sep; 150(3):323-9. PMID: 6090539.
      Citations: 19     Fields:    Translation:HumansCellsCTClinical Trials
    329. Whitley RJ. Treatment of human herpesvirus infections with special reference to encephalitis. J Antimicrob Chemother. 1984 Aug; 14 Suppl A:57-74. PMID: 6092319.
      Citations: 2     Fields:    Translation:HumansCTClinical Trials
    330. Overall JC, Whitley RJ, Yeager AS, McCracken GH, Nelson JD. Prophylactic or anticipatory antiviral therapy for newborns exposed to herpes simplex infection. Pediatr Infect Dis. 1984 May-Jun; 3(3):193-5. PMID: 6539912.
      Citations: 2     Fields:    Translation:Humans
    331. Garcia JH, Colon LE, Whitley RJ, Wilmes FJ. Diagnosis of viral encephalitis by brain biopsy. Semin Diagn Pathol. 1984 May; 1(2):71-81. PMID: 6400632.
      Citations: 1     Fields:    Translation:HumansCells
    332. Whitley RJ, Spruance S, Hayden FG, Overall J, Alford CA, Gwaltney JM, Soong SJ. Vidarabine therapy for mucocutaneous herpes simplex virus infections in the immunocompromised host. J Infect Dis. 1984 Jan; 149(1):1-8. PMID: 6693782.
      Citations: 4     Fields:    Translation:HumansCTClinical Trials
    333. Dworsky M, Pass RF, Stagno S, Whitley RJ. Therapeutic approaches to the control of cytomegalovirus infections. Birth Defects Orig Artic Ser. 1984; 20(1):345-52. PMID: 6329371.
      Citations: 1     Fields:    Translation:HumansCells
    334. Chatterjee S, Lakeman AD, Whitley RJ, Hunter E. Effect of cloned human interferons on the replication of and cell fusion induced by herpes simplex virus. Virus Res. 1984 Jan; 1(1):81-7. PMID: 6099653.
      Citations: 8     Fields:    Translation:HumansCells
    335. Whitley RJ, Yeager A, Kartus P, Bryson Y, Connor JD, Alford CA, Nahmias A, Soong SJ. Neonatal herpes simplex virus infection: follow-up evaluation of vidarabine therapy. Pediatrics. 1983 Dec; 72(6):778-85. PMID: 6359047.
      Citations: 19     Fields:    Translation:HumansCTClinical Trials
    336. Gnann JW, Barton NH, Whitley RJ. Acyclovir: mechanism of action, pharmacokinetics, safety and clinical applications. Pharmacotherapy. 1983 Sep-Oct; 3(5):275-83. PMID: 6359082.
      Citations: 29     Fields:    Translation:HumansAnimalsCTClinical Trials
    337. Coleman RM, Bailey PD, Whitley RJ, Keyserling H, Nahmias AJ. ELISA for the detection of herpes simplex virus antigens in the cerebrospinal fluid of patients with encephalitis. J Virol Methods. 1983 Sep; 7(3):117-25. PMID: 6315749.
      Citations: 8     Fields:    Translation:HumansCells
    338. Whitley RJ. Interim summary of mortality in herpes simplex encephalitis and neonatal herpes simplex virus infections: vidarabine versus acyclovir. J Antimicrob Chemother. 1983 Sep; 12 Suppl B:105-12. PMID: 6355046.
      Citations: 7     Fields:    Translation:HumansCTClinical Trials
    339. Morawetz RB, Whitley RJ, Murphy DM. Experience with brain biopsy for suspected herpes encephalitis: a review of forty consecutive cases. Neurosurgery. 1983 Jun; 12(6):654-7. PMID: 6308497.
      Citations: 7     Fields:    Translation:HumansCells
    340. Whitley RJ, Crist WM. Management of infections. Pediatr Ann. 1983 Jun; 12(6):445-9. PMID: 6348682.
      Citations:    Fields:    Translation:Humans
    341. Volpi A, Whitley RJ, Ceballos R, Stagno S, Pereira L. Rapid diagnosis of pneumonia due to cytomegalovirus with specific monoclonal antibodies. J Infect Dis. 1983 Jun; 147(6):1119-20. PMID: 6304205.
      Citations: 13     Fields:    Translation:HumansCells
    342. Whitley RJ, Alford CA. Towards therapy and prevention of herpetic infections. Semin Perinatol. 1983 Jan; 7(1):64-81. PMID: 6302915.
      Citations:    Fields:    Translation:Humans
    343. Whitley R, Lakeman AD, Nahmias A, Roizman B. Dna restriction-enzyme analysis of herpes simplex virus isolates obtained from patients with encephalitis. N Engl J Med. 1982 Oct 21; 307(17):1060-2. PMID: 6289100.
      Citations: 40     Fields:    Translation:HumansCells
    344. Whitley RJ, Soong SJ, Dolin R, Betts R, Linnemann C, Alford CA. Early vidarabine therapy to control the complications of herpes zoster in immunosuppressed patients. N Engl J Med. 1982 Oct 14; 307(16):971-5. PMID: 7110300.
      Citations: 23     Fields:    Translation:HumansCTClinical Trials
    345. Furlow TW, Whitley RJ, Wilmes FJ. Repeated suppression of Creutzfeldt-Jakob disease with vidarabine. Lancet. 1982 Sep 04; 2(8297):564-5. PMID: 6125725.
      Citations: 9     Fields:    Translation:Humans
    346. Whitley RJ, Blum MR, Barton N, de Miranda P. Pharmacokinetics of acyclovir in humans following intravenous administration. A model for the development of parenteral antivirals. Am J Med. 1982 Jul 20; 73(1A):165-71. PMID: 7102700.
      Citations: 16     Fields:    Translation:Humans
    347. Whitley R, Barton N, Collins E, Whelchel J, Diethelm AG. Mucocutaneous herpes simplex virus infections in immunocompromised patients. A model for evaluation of topical antiviral agents. Am J Med. 1982 Jul 20; 73(1A):236-40. PMID: 7048915.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    348. Whitley R, Hilty M, Haynes R, Bryson Y, Connor JD, Soong SJ, Alford CA. Vidarabine therapy of varicella in immunosuppressed patients. J Pediatr. 1982 Jul; 101(1):125-31. PMID: 7045313.
      Citations: 14     Fields:    Translation:HumansCellsCTClinical Trials
    349. Nahmias AJ, Whitley RJ, Visintine AN, Takei Y, Alford CA. Herpes simplex virus encephalitis: laboratory evaluations and their diagnostic significance. J Infect Dis. 1982 Jun; 145(6):829-36. PMID: 6282983.
      Citations: 70     Fields:    Translation:HumansCells
    350. Alford CA, Dolin R, Hirsch MS, Karchmer AW, Whitley RJ. Herpes simplex encephalitis and clinical trial design. Lancet. 1982 May 01; 1(8279):1013. PMID: 6122821.
      Citations: 4     Fields:    Translation:HumansCTClinical Trials
    351. Whitley RJ, Alford CA. Herpesvirus infections in childhood: diagnostic dilemmas and therapy. Pediatr Infect Dis. 1982 Mar-Apr; 1(2):81-4. PMID: 7177907.
      Citations: 1     Fields:    Translation:Humans
    352. Whitley RJ, Soong SJ, Linneman C, Liu C, Pazin G, Alford CA. Herpes simplex encephalitis. Clinical Assessment. JAMA. 1982 Jan 15; 247(3):317-20. PMID: 6275134.
      Citations: 56     Fields:    Translation:HumansCells
    353. Pass RF, Dworsky ME, Whitley RJ, August AM, Stagno S, Alford CA. Specific lymphocyte blastogenic responses in children with cytomegalovirus and herpes simplex virus infections acquired early in infancy. Infect Immun. 1981 Oct; 34(1):166-70. PMID: 6271679; PMCID: PMC350838.
      Citations: 10     Fields:    Translation:HumansCells
    354. Whitley RJ, Alford CA. Preventive and therapeutic approaches to the newborn infant with perinatal viral and toxoplasma infections. Clin Perinatol. 1981 Oct; 8(3):591-604. PMID: 6171374.
      Citations:    Fields:    Translation:HumansPHPublic Health
    355. Stagno S, Brasfield DM, Brown MB, Cassell GH, Pifer LL, Whitley RJ, Tiller RE. Infant pneumonitis associated with cytomegalovirus, Chlamydia, Pneumocystis, and Ureaplasma: a prospective study. Pediatrics. 1981 Sep; 68(3):322-9. PMID: 6269042.
      Citations: 30     Fields:    Translation:HumansCells
    356. Lee FK, Takei Y, Dannenbarger J, Visintine A, Whitley R, Nahmias A. Rapid detection of viruses in biopsy or autopsy specimens by the pseudoreplica method of electron microscopy. Am J Surg Pathol. 1981 Sep; 5(6):565-72. PMID: 6275724.
      Citations: 1     Fields:    Translation:HumansCells
    357. Whitley RJ, Alford CA. Antiviral agents: clinical status report. Hosp Pract (Off Ed). 1981 Jul; 16(7):109-21. PMID: 6788666.
      Citations: 2     Fields:    Translation:Humans
    358. Whitley RJ, Soong SJ, Hirsch MS, Karchmer AW, Dolin R, Galasso G, Dunnick JK, Alford CA. Herpes simplex encephalitis: vidarabine therapy and diagnostic problems. N Engl J Med. 1981 Feb 05; 304(6):313-8. PMID: 6255332.
      Citations: 51     Fields:    Translation:HumansCells
    359. Whitley R. Diagnosis and treatment of herpes simplex encephalitis. Annu Rev Med. 1981; 32:335-40. PMID: 7013672.
      Citations: 6     Fields:    Translation:Humans
    360. Whitley RJ, Tucker BC, Kinkel AW, Barton NH, Pass RF, Whelchel JD, Cobbs CG, Diethelm AG, Buchanan RA. Pharmacology, tolerance, and antiviral activity of vidarabine monophosphate in humans. Antimicrob Agents Chemother. 1980 Nov; 18(5):709-15. PMID: 6160811; PMCID: PMC284080.
      Citations: 15     Fields:    Translation:Humans
    361. Whitley R, Alford C, Hess F, Buchanan R. Vidarabine: a preliminary review of its pharmacological properties and therapeutic use. Drugs. 1980 Oct; 20(4):267-82. PMID: 6998693.
      Citations: 20     Fields:    Translation:Humans
    362. Whitley RJ, Nahmias AJ, Soong SJ, Galasso GG, Fleming CL, Alford CA. Vidarabine therapy of neonatal herpes simplex virus infection. Pediatrics. 1980 Oct; 66(4):495-501. PMID: 7001331.
      Citations: 61     Fields:    Translation:HumansCTClinical Trials
    363. Whitley RJ, Nahmias AJ, Visintine AM, Fleming CL, Alford CA. The natural history of herpes simplex virus infection of mother and newborn. Pediatrics. 1980 Oct; 66(4):489-94. PMID: 6253866.
      Citations: 76     Fields:    Translation:HumansCells
    364. Whitley RJ, Alford CA. Herpes simplex encephalitis: need for accurate diagnosis. JAMA. 1980 Jul 25; 244(4):371-2. PMID: 7392134.
      Citations: 1     Fields:    Translation:HumansCells
    365. Pass RF, Whitley RJ, Diethelm AG, Whelchel JD, Reynolds DW, Alford CA. Cytomegalovirus infection in patients with renal transplants: potentiation by antithymocyte globulin and an incompatible graft. J Infect Dis. 1980 Jul; 142(1):9-17. PMID: 6249875.
      Citations: 16     Fields:    Translation:HumansCellsCTClinical Trials
    366. Dworsky M, Whitley R, Alford C. Herpes zoster in early infancy. Am J Dis Child. 1980 Jun; 134(6):618-9. PMID: 7386437.
      Citations: 7     Fields:    Translation:Humans
    367. Buchanan RA, Kinkel AW, Alford CA, Whitley RJ. Plasma levels and urinary excretion of vidarabine after repeated dosing. Clin Pharmacol Ther. 1980 May; 27(5):690-6. PMID: 7371366.
      Citations: 5     Fields:    Translation:HumansCells
    368. de Miranda P, Whitley RJ, Blum MR, Keeney RE, Barton N, Cocchetto DM, Good S, Hemstreet GP, Kirk LE, Page DA, Elion GB. Acyclovir kinetics after intravenous infusion. Clin Pharmacol Ther. 1979 Dec; 26(6):718-28. PMID: 227639.
      Citations: 24     Fields:    Translation:Humans
    369. Whelchel JD, Pass RF, Diethelm AG, Whitley RJ, Alford CA. Effect of primary and recurrent cytomegalovirus infections upon graft and patient survival after renal transplantation. Transplantation. 1979 Dec; 28(6):443-6. PMID: 229592.
      Citations: 10     Fields:    Translation:Humans
    370. Mazur MH, Whitley RJ, Dolin R. Serum antibody levels as risk factors in the dissemination of herpes zoster. Arch Intern Med. 1979 Dec; 139(12):1341-5. PMID: 229783.
      Citations: 3     Fields:    Translation:HumansCells
    371. Pass RF, Whitley RJ, Whelchel JD, Diethelm AG, Reynolds DW, Alford CA. Identification of patients with increased risk of infection with herpes simplex virus after renal transplantation. J Infect Dis. 1979 Oct; 140(4):487-92. PMID: 390063.
      Citations: 21     Fields:    Translation:HumansCells
    372. Whitley RJ, Arvin A, Galasso G, Dunnick J. Distribution of adenine arabinoside and interferon. JAMA. 1979 Sep 21; 242(12):1259-60. PMID: 480535.
      Citations:    Fields:    Translation:Humans
    373. Pass RF, Whitley RJ, Diethelm AG, Whelchel JD, Reynolds DW, Alford CA. Outcome of renal transplantation in patients with primary cytomegalovirus infection. Transplant Proc. 1979 Jun; 11(2):1288-90. PMID: 224539.
      Citations: 4     Fields:    Translation:Humans
    374. Whitley RJ, Alford CA. Developmental aspects of adenine arabinoside for parenteral therapy of human herpesvirus infections. Adv Ophthalmol. 1979; 38:288-96. PMID: 230722.
      Citations:    Fields:    Translation:HumansAnimals
    375. Chen AB, Ben-Porat T, Whitley RJ, Kaplan AS. Purification and characterization of proteins excreted by cells infected with herpes simplex virus and their use in diagnosis. Virology. 1978 Dec; 91(2):234-42. PMID: 217149.
      Citations: 6     Fields:    Translation:HumansCells
    376. Tucker BA, Doekel RC, Whitley RJ, Dismukes WE. Herpes simplex virus encephalitis: an atypical presentation. South Med J. 1978 Nov; 71(11):1431-3. PMID: 715494.
      Citations:    Fields:    Translation:Humans
    377. Whitley RJ, Alford CA. Current status of antiviral chemotherapy. South Med J. 1978 Sep; 71(9):1134-40. PMID: 210524.
      Citations:    Fields:    Translation:Humans
    378. Dolin R, Reichman RC, Mazur MH, Whitley RJ. NIH conference. Herpes zoster-varicella infections in immunosuppressed patients. Ann Intern Med. 1978 Sep; 89(3):375-88. PMID: 210697.
      Citations: 48     Fields:    Translation:HumansCellsPHPublic Health
    379. Pass RF, Long WK, Whitley RJ, Soong SJ, Diethelm AG, Reynolds DW, Alford CA. Productive infection with cytomegalovirus and herpes simplex virus in renal transplant recipients: role of source of kidney. J Infect Dis. 1978 May; 137(5):556-63. PMID: 207784.
      Citations: 7     Fields:    Translation:HumansCells
    380. Whitley RJ, Alford CA. Developmental aspects of selected antiviral chemotherapeutic agents. Annu Rev Microbiol. 1978; 32:285-300. PMID: 213011.
      Citations: 6     Fields:    Translation:HumansCells
    381. Whitley RJ, Soong SJ, Dolin R, Galasso GJ, Ch'ien LT, Alford CA. Adenine arabinoside therapy of biopsy-proved herpes simplex encephalitis. J Med Assoc State Ala. 1977 Sep; 47(3):37-42, 66. PMID: 903726.
      Citations:    Fields:    Translation:Humans
    382. Whitley RJ, Soong SJ, Dolin R, Galasso GJ, Ch'ien LT, Alford CA. Adenine arabinoside therapy of biopsy-proved herpes simplex encephalitis. National Institute of Allergy and Infectious Diseases collaborative antiviral study. N Engl J Med. 1977 Aug 11; 297(6):289-94. PMID: 195208.
      Citations: 132     Fields:    Translation:HumansCellsCTClinical Trials
    383. Whitley RJ, Brasfield D, Reynolds DW, Stagno S, Tiller RE, Alford CA. Protracted pneumonitis in young infants associated with perinatally acquired cytomegaloviral infection. J Pediatr. 1976 Jul; 89(1):16-22. PMID: 180275.
      Citations: 12     Fields:    Translation:HumansCells
    384. Alford CA, Whitley RJ. Treatment of infections due to Herpesvirus in humans: a critical review of the state of the art. J Infect Dis. 1976 Jun; 133 Suppl:A101-8. PMID: 180191.
      Citations: 6     Fields:    Translation:HumansAnimals
    385. Ch'ien LT, Whitley RJ, Alford CA, Galasso GJ. Adenine arabinoside for therapy of herpes zoster in immunosuppressed patients: preliminary results of a collaborative study. J Infect Dis. 1976 Jun; 133 Suppl:A184-91. PMID: 180198.
      Citations: 3     Fields:    Translation:HumansCellsCTClinical Trials
    386. Whitley RJ, Ch'ien LT, Dolin R, Galasso GJ, Alford CA. Adenine arabinoside therapy of herpes zoster in the immunosuppressed. NIAID collaborative antiviral study. N Engl J Med. 1976 May 27; 294(22):1193-9. PMID: 177866.
      Citations: 45     Fields:    Translation:HumansCellsCTClinical Trials
    387. Alford CA, Whitley R. Therapy of herpetic infections in man: a status report. Adv Pathobiol. 1976; (5):159-72. PMID: 220853.
      Citations:    Fields:    Translation:Humans
    388. Ceballos R, Ch'ien LT, Whitley RJ, Brans YW. Cerebellar hypoplasia in an infant with congenital cytomegalovirus infection. Pediatrics. 1976 Jan; 57(1):155-7. PMID: 174055.
      Citations: 3     Fields:    Translation:Humans
    389. Whitley RJ. The hospital founded in 1838 by W. J. Little. Med Biol Illus. 1975 Nov; 25(4):240-4. PMID: 778507.
      Citations:    Fields:    
    390. Ch'ien LT, Whitley RJ, Nahmias AJ, Lewin EB, Linnemann CC, Frenkel LD, Bellanti JA, Buchanan RA, Alford DA. Antiviral chemotherapy and neonatal herpes simplex virus infecition: a pilot study--experience with adenine arabinoside (ARA-A). Pediatrics. 1975 May; 55(5):678-85. PMID: 165453.
      Citations: 11     Fields:    Translation:HumansCells
    391. Whitley RJ, Ch'ien LT, Alford CA. Neonatal herpes simplex virus infection. Int Ophthalmol Clin. 1975; 15(4):141-9. PMID: 1225858.
      Citations:    Fields:    Translation:Humans
    392. Ch'ien LT, Cannon NJ, Whitley RJ, Diethelm AG, Dismukes WE, Scott CW, Buchanan RA, Alford CA. Effect of adenine arabinoside on cytomegalovirus infections. J Infect Dis. 1974 Jul; 130(1):32-9. PMID: 4366288.
      Citations: 14     Fields:    Translation:HumansCells
    393. Ch'ien LT, Cannon NJ, Charamella LJ, Dismukes WE, Whitley RJ, Buchanan RA, Alford CA. Effect of adenine arabinoside on severe Herpesvirus hominis infections in man. J Infect Dis. 1973 Nov; 128(5):658-63. PMID: 4358651.
      Citations: 20     Fields:    Translation:HumansCells
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