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Richard Whitley

AddressChicago IL 60637
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Gnann JW, Agrawal A, Hart J, Buitrago M, Carson P, Hanfelt-Goade D, Tyler K, Spotkov J, Freifeld A, Moore T, Reyno J, Masur H, Jester P, Dale I, Li Y, Aban I, Lakeman FD, Whitley RJ. Lack of Efficacy of High-Titered Immunoglobulin in Patients with West Nile Virus Central Nervous System Disease. Emerg Infect Dis. 2019 11; 25(11):2064-2073. PMID: 31625835.
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    2. Totsch SK, Schlappi C, Kang KD, Ishizuka AS, Lynn GM, Fox B, Beierle EA, Whitley RJ, Markert JM, Gillespie GY, Bernstock JD, Friedman GK. Oncolytic herpes simplex virus immunotherapy for brain tumors: current pitfalls and emerging strategies to overcome therapeutic resistance. Oncogene. 2019 Aug; 38(34):6159-6171. PMID: 31289361.
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    3. Whitley RJ. Congenital Cytomegalovirus and Neonatal Herpes Simplex Virus Infections: To Treat or Not to Treat? Pediatr Infect Dis J. 2019 Jun; 38(6S Suppl 1):S60-S63. PMID: 31205247.
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    4. Akhtar LN, Bowen CD, Renner DW, Pandey U, Della Fera AN, Kimberlin DW, Prichard MN, Whitley RJ, Weitzman MD, Szpara ML. Genotypic and Phenotypic Diversity of Herpes Simplex Virus 2 within the Infected Neonatal Population. mSphere. 2019 02 27; 4(1). PMID: 30814317.
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    5. Whitley R, Baines J. Clinical management of herpes simplex virus infections: past, present, and future. F1000Res. 2018; 7. PMID: 30443341.
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    6. Gnann JW, Whitley RJ. Herpes Simplex Encephalitis: an Update. Curr Infect Dis Rep. 2017 Mar; 19(3):13. PMID: 28251511.
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    7. Nye S, Whitley RJ, Kong M. Viral Infection in the Development and Progression of Pediatric Acute Respiratory Distress Syndrome. Front Pediatr. 2016; 4:128. PMID: 27933286.
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    8. Gnann JW, Whitley RJ. Genital Herpes. N Engl J Med. 2016 11 10; 375(19):1906. PMID: 27959656.
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    9. Gnann JW, Whitley RJ. CLINICAL PRACTICE. Genital Herpes. N Engl J Med. 2016 Aug 18; 375(7):666-74. PMID: 27532832.
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    10. Everts M, Cihlar T, Bostwick JR, Whitley RJ. Accelerating Drug Development: Antiviral Therapies for Emerging Viruses as a Model. Annu Rev Pharmacol Toxicol. 2017 01 06; 57:155-169. PMID: 27483339.
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    11. Everts M, Suto MJ, Painter GR, Whitley RJ. Consortia's critical role in developing medical countermeasures for re-emerging viral infections: a USA perspective. Future Virol. 2016 Mar; 11(3):187-195. PMID: 27325914.
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    12. Monto AS, Dobson J, Pocock S, Whitley RJ. Oseltamivir for influenza - Authors' reply. Lancet. 2016 Jan 09; 387(10014):125. PMID: 26841996.
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    13. Whitley RJ. Herpes Simplex Virus Infections of the Central Nervous System. Continuum (Minneap Minn). 2015 Dec; 21(6 Neuroinfectious Disease):1704-13. PMID: 26633784.
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    14. Kong MY, Whitley RJ, Peng N, Oster R, Schoeb TR, Sullender W, Ambalavanan N, Clancy JP, Gaggar A, Blalock JE. Addendum: Kong, M.Y.; Whitley, R.J.; Peng, N.; Oster, R.; Schoeb, T.R.; Sullender, W.; Ambalavanan, N.; Clancy, J.P.; Gaggar, A.; Blalock J.E. Matrix Metalloproteinase-9 Mediates RSV Infection in Vitro and in Vivo. Viruses 2015, 30, 7, 4230–4253. Viruses. 2015 Oct; 7(10):5609. PMID: 26702463.
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    15. Monto AS, Dobson J, Pocock S, Whitley RJ. Oseltamivir for influenza - Authors' reply. Lancet. 2015 Sep 19; 386(9999):1135-6. PMID: 26461902.
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    16. Kong MY, Whitley RJ, Peng N, Oster R, Schoeb TR, Sullender W, Ambalavanan N, Clancy JP, Gaggar A, Blalock JE. Matrix Metalloproteinase-9 Mediates RSV Infection in Vitro and in Vivo. Viruses. 2015 Jul 30; 7(8):4230-53. PMID: 26264019.
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    17. Gnann JW, Sköldenberg B, Hart J, Aurelius E, Schliamser S, Studahl M, Eriksson BM, Hanley D, Aoki F, Jackson AC, Griffiths P, Miedzinski L, Hanfelt-Goade D, Hinthorn D, Ahlm C, Aksamit A, Cruz-Flores S, Dale I, Cloud G, Jester P, Whitley RJ. Herpes Simplex Encephalitis: Lack of Clinical Benefit of Long-term Valacyclovir Therapy. Clin Infect Dis. 2015 Sep 01; 61(5):683-91. PMID: 25956891.
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    18. Abzug MJ, Michaels MG, Wald E, Jacobs RF, Romero JR, Sánchez PJ, Wilson G, Krogstad P, Storch GA, Lawrence R, Shelton M, Palmer A, Robinson J, Dennehy P, Sood SK, Cloud G, Jester P, Acosta EP, Whitley R, Kimberlin D. A Randomized, Double-Blind, Placebo-Controlled Trial of Pleconaril for the Treatment of Neonates With Enterovirus Sepsis. J Pediatric Infect Dis Soc. 2016 Mar; 5(1):53-62. PMID: 26407253.
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    19. Simões EA, DeVincenzo JP, Boeckh M, Bont L, Crowe JE, Griffiths P, Hayden FG, Hodinka RL, Smyth RL, Spencer K, Thirstrup S, Walsh EE, Whitley RJ. Challenges and opportunities in developing respiratory syncytial virus therapeutics. J Infect Dis. 2015 Mar 15; 211 Suppl 1:S1-S20. PMID: 25713060.
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    20. Kimberlin DW, Jester PM, Sánchez PJ, Ahmed A, Arav-Boger R, Michaels MG, Ashouri N, Englund JA, Estrada B, Jacobs RF, Romero JR, Sood SK, Whitworth MS, Abzug MJ, Caserta MT, Fowler S, Lujan-Zilbermann J, Storch GA, DeBiasi RL, Han JY, Palmer A, Weiner LB, Bocchini JA, Dennehy PH, Finn A, Griffiths PD, Luck S, Gutierrez K, Halasa N, Homans J, Shane AL, Sharland M, Simonsen K, Vanchiere JA, Woods CR, Sabo DL, Aban I, Kuo H, James SH, Prichard MN, Griffin J, Giles D, Acosta EP, Whitley RJ. Valganciclovir for symptomatic congenital cytomegalovirus disease. N Engl J Med. 2015 Mar 05; 372(10):933-43. PMID: 25738669.
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    21. Chow FC, Glaser CA, Sheriff H, Xia D, Messenger S, Whitley R, Venkatesan A. Use of clinical and neuroimaging characteristics to distinguish temporal lobe herpes simplex encephalitis from its mimics. Clin Infect Dis. 2015 May 01; 60(9):1377-83. PMID: 25637586.
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    22. Dobson J, Whitley RJ, Pocock S, Monto AS. Oseltamivir treatment for influenza in adults: a meta-analysis of randomised controlled trials. Lancet. 2015 May 02; 385(9979):1729-1737. PMID: 25640810.
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    23. Whitley RJ. Editorial commentary: Waning efficacy of the herpes zoster vaccine. Clin Infect Dis. 2015 Mar 15; 60(6):910-1. PMID: 25416752.
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    24. Prichard MN, Whitley RJ. The development of new therapies for human herpesvirus 6. Curr Opin Virol. 2014 Dec; 9:148-53. PMID: 25462447.
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    25. Whitley R, Laughlin A, Carson S, Mitha E, Tellier G, Stich M, Elder J, Alexander WJ, Dobo S, Collis P, Sheridan WP. Single dose peramivir for the treatment of acute seasonal influenza: integrated analysis of efficacy and safety from two placebo-controlled trials. Antivir Ther. 2015; 20(7):709-19. PMID: 25318121.
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    26. DeVincenzo JP, Whitley RJ, Mackman RL, Scaglioni-Weinlich C, Harrison L, Farrell E, McBride S, Lambkin-Williams R, Jordan R, Xin Y, Ramanathan S, O'Riordan T, Lewis SA, Li X, Toback SL, Lin SL, Chien JW. Oral GS-5806 activity in a respiratory syncytial virus challenge study. N Engl J Med. 2014 Aug 21; 371(8):711-22. PMID: 25140957.
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    27. Jackson JD, McMorris AM, Roth JC, Coleman JM, Whitley RJ, Gillespie GY, Carroll SL, Markert JM, Cassady KA. Assessment of oncolytic HSV efficacy following increased entry-receptor expression in malignant peripheral nerve sheath tumor cell lines. Gene Ther. 2014 Nov; 21(11):984-90. PMID: 25119379.
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    28. Kamal MA, Acosta EP, Kimberlin DW, Gibiansky L, Jester P, Niranjan V, Rath B, Clinch B, Sánchez PJ, Ampofo K, Whitley R, Rayner CR. The posology of oseltamivir in infants with influenza infection using a population pharmacokinetic approach. Clin Pharmacol Ther. 2014 Sep; 96(3):380-9. PMID: 24865390.
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    29. Hart J, Tillman G, Kraut MA, Chiang HS, Strain JF, Li Y, Agrawal AG, Jester P, Gnann JW, Whitley RJ. West Nile virus neuroinvasive disease: neurological manifestations and prospective longitudinal outcomes. BMC Infect Dis. 2014 May 09; 14:248. PMID: 24884681.
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    30. King L, Tulandi T, Whitley R, Constantinescu T, Ells C, Zelkowitz P. What's the message? A content analysis of newspaper articles about assisted reproductive technology from 2005 to 2011. Hum Fertil (Camb). 2014 Jun; 17(2):124-32. PMID: 24669833.
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    31. Roth JC, Cassady KA, Cody JJ, Parker JN, Price KH, Coleman JM, Peggins JO, Noker PE, Powers NW, Grimes SD, Carroll SL, Gillespie GY, Whitley RJ, Markert JM. Evaluation of the safety and biodistribution of M032, an attenuated herpes simplex virus type 1 expressing hIL-12, after intracerebral administration to aotus nonhuman primates. Hum Gene Ther Clin Dev. 2014 Mar; 25(1):16-27. PMID: 24649838.
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    32. Roth JC, Cassady KA, Cody JJ, Parker JN, Price KH, Coleman JM, Peggins JO, Noker PE, Powers N, Grimes S, Carroll SL, Gillespie GY, Whitley R, Markert J. Evaluation of the Safety and Biodistribution of M032, an Attenuated HSV-1 Virus Expressing hIL-12, After Intracerebral Administration to Aotus Non-Human Primates. Hum Gene Ther Clin Dev. 2014 Feb 28. PMID: 24579875.
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    33. Markert JM, Razdan SN, Kuo HC, Cantor A, Knoll A, Karrasch M, Nabors LB, Markiewicz M, Agee BS, Coleman JM, Lakeman AD, Palmer CA, Parker JN, Whitley RJ, Weichselbaum RR, Fiveash JB, Gillespie GY. A phase 1 trial of oncolytic HSV-1, G207, given in combination with radiation for recurrent GBM demonstrates safety and radiographic responses. Mol Ther. 2014 May; 22(5):1048-55. PMID: 24572293.
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    34. Whitley RJ, Prichard M. A novel potential therapy for HSV. N Engl J Med. 2014 Jan 16; 370(3):273-4. PMID: 24428473.
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    35. Widener RW, Whitley RJ. Herpes simplex virus. Handb Clin Neurol. 2014; 123:251-63. PMID: 25015489.
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    36. Gaston DC, Odom CI, Li L, Markert JM, Roth JC, Cassady KA, Whitley RJ, Parker JN. Production of bioactive soluble interleukin-15 in complex with interleukin-15 receptor alpha from a conditionally-replicating oncolytic HSV-1. PLoS One. 2013; 8(11):e81768. PMID: 24312353.
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    37. Venkatesan A, Tunkel AR, Bloch KC, Lauring AS, Sejvar J, Bitnun A, Stahl JP, Mailles A, Drebot M, Rupprecht CE, Yoder J, Cope JR, Wilson MR, Whitley RJ, Sullivan J, Granerod J, Jones C, Eastwood K, Ward KN, Durrheim DN, Solbrig MV, Guo-Dong L, Glaser CA. Case definitions, diagnostic algorithms, and priorities in encephalitis: consensus statement of the international encephalitis consortium. Clin Infect Dis. 2013 Oct; 57(8):1114-28. PMID: 23861361.
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    38. Whitley RJ, Markert JM. Viral therapy of glioblastoma multiforme. Proc Natl Acad Sci U S A. 2013 Jul 16; 110(29):11672-3. PMID: 23836634.
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    39. Whitley RJ, Boucher CA, Lina B, Nguyen-Van-Tam JS, Osterhaus A, Schutten M, Monto AS. Global assessment of resistance to neuraminidase inhibitors, 2008-2011: the Influenza Resistance Information Study (IRIS). Clin Infect Dis. 2013 May; 56(9):1197-205. PMID: 23307766.
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    40. Roizman B, Whitley RJ. An inquiry into the molecular basis of HSV latency and reactivation. Annu Rev Microbiol. 2013; 67:355-74. PMID: 24024635.
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    41. Kimberlin DW, Acosta EP, Prichard MN, Sánchez PJ, Ampofo K, Lang D, Ashouri N, Vanchiere JA, Abzug MJ, Abughali N, Caserta MT, Englund JA, Sood SK, Spigarelli MG, Bradley JS, Lew J, Michaels MG, Wan W, Cloud G, Jester P, Lakeman FD, Whitley RJ. Oseltamivir pharmacokinetics, dosing, and resistance among children aged <2 years with influenza. J Infect Dis. 2013 Mar 01; 207(5):709-20. PMID: 23230059.
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    42. Van Wagoner NJ, Brown E, Whitley R, Hook EW. Predictors of undiagnosed herpes simplex virus type 2 seropositivity among persons attending an HIV care clinic. Sex Transm Dis. 2012 Nov; 39(11):857-9. PMID: 23064534.
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    43. Whitley RJ. Changing epidemiology of herpes simplex virus infections. Clin Infect Dis. 2013 Feb; 56(3):352-3. PMID: 23087393.
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    44. Rha B, Redden D, Benfield M, Lakeman F, Whitley RJ, Shimamura M. Correlation and clinical utility of pp65 antigenemia and quantitative polymerase chain reaction assays for detection of cytomegalovirus in pediatric renal transplant patients. Pediatr Transplant. 2012 Sep; 16(6):627-37. PMID: 22694244.
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    45. Markert JM, Cody JJ, Parker JN, Coleman JM, Price KH, Kern ER, Quenelle DC, Lakeman AD, Schoeb TR, Palmer CA, Cartner SC, Gillespie GY, Whitley RJ. Preclinical evaluation of a genetically engineered herpes simplex virus expressing interleukin-12. J Virol. 2012 May; 86(9):5304-13. PMID: 22379082.
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    46. Whitley RJ. The use of antiviral drugs during the neonatal period. Clin Perinatol. 2012 Mar; 39(1):69-81. PMID: 22341538.
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    47. Coen DM, Whitley RJ. Antiviral drugs and antiviral drug resistance. Curr Opin Virol. 2011 Dec; 1(6):545-7. PMID: 22440912.
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    48. Kimberlin DW, Whitley RJ, Wan W, Powell DA, Storch G, Ahmed A, Palmer A, Sánchez PJ, Jacobs RF, Bradley JS, Robinson JL, Shelton M, Dennehy PH, Leach C, Rathore M, Abughali N, Wright P, Frenkel LM, Brady RC, Van Dyke R, Weiner LB, Guzman-Cottrill J, McCarthy CA, Griffin J, Jester P, Parker M, Lakeman FD, Kuo H, Lee CH, Cloud GA. Oral acyclovir suppression and neurodevelopment after neonatal herpes. N Engl J Med. 2011 Oct 06; 365(14):1284-92. PMID: 21991950.
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    49. McJunkin JE, Nahata MC, De Los Reyes EC, Hunt WG, Caceres M, Khan RR, Chebib MG, Taravath S, Minnich LL, Carr R, Welch CA, Whitley RJ. Safety and pharmacokinetics of ribavirin for the treatment of la crosse encephalitis. Pediatr Infect Dis J. 2011 Oct; 30(10):860-5. PMID: 21544005.
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    50. Cunningham A, Griffiths P, Leone P, Mindel A, Patel R, Stanberry L, Whitley R. Current management and recommendations for access to antiviral therapy of herpes labialis. J Clin Virol. 2012 Jan; 53(1):6-11. PMID: 21889905.
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    51. Norberg P, Tyler S, Severini A, Whitley R, Liljeqvist JÅ, Bergström T. A genome-wide comparative evolutionary analysis of herpes simplex virus type 1 and varicella zoster virus. PLoS One. 2011; 6(7):e22527. PMID: 21799886.
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    52. Everts M, Knight WB, Harris DR, Secrist JA, Whitley RJ. The Alabama Drug Discovery Alliance: a collaborative partnership to facilitate academic drug discovery. Pharm Res. 2011 Jul; 28(7):1454-9. PMID: 21448756.
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    53. Thompson C, Whitley R. Neonatal herpes simplex virus infections: where are we now? Adv Exp Med Biol. 2011; 697:221-30. PMID: 21120729.
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    54. Cardo D, Dennehy PH, Halverson P, Fishman N, Kohn M, Murphy CL, Whitley RJ. Moving toward elimination of healthcare-associated infections: a call to action. Infect Control Hosp Epidemiol. 2010 Nov; 31(11):1101-5. PMID: 20929300.
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    55. Cardo D, Dennehy PH, Halverson P, Fishman N, Kohn M, Murphy CL, Whitley RJ. Moving toward elimination of healthcare-associated infections: a call to action. Am J Infect Control. 2010 Nov; 38(9):671-5. PMID: 21058460.
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    56. James SH, Whitley RJ. Treatment of herpes simplex virus infections in pediatric patients: current status and future needs. Clin Pharmacol Ther. 2010 Nov; 88(5):720-4. PMID: 20881952.
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    57. Acosta EP, Jester P, Gal P, Wimmer J, Wade J, Whitley RJ, Kimberlin DW. Oseltamivir dosing for influenza infection in premature neonates. J Infect Dis. 2010 Aug 15; 202(4):563-6. PMID: 20594104.
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    58. Whitley RJ, Volpi A, McKendrick M, Wijck Av, Oaklander AL. Management of herpes zoster and post-herpetic neuralgia now and in the future. J Clin Virol. 2010 May; 48 Suppl 1:S20-8. PMID: 20510264.
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    59. Whitley RJ. Of ferrets and humans: influenza pathogenesis. J Infect Dis. 2010 Apr 01; 201(7):976-7. PMID: 20187748.
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    60. Van Wagoner NJ, Geisler WM, Sizemore JM, Whitley R, Hook EW. Herpes simplex virus in African American heterosexual males: the roles of age and male circumcision. Sex Transm Dis. 2010 Apr; 37(4):217-22. PMID: 19910861.
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    61. Kimberlin DW, Shalabi M, Abzug MJ, Lang D, Jacobs RF, Storch G, Bradley JS, Wade KC, Ramilo O, Romero JR, Shelton M, Leach C, Guzman-Cottrill J, Robinson J, Abughali N, Englund J, Griffin J, Jester P, Cloud GA, Whitley RJ. Safety of oseltamivir compared with the adamantanes in children less than 12 months of age. Pediatr Infect Dis J. 2010 Mar; 29(3):195-8. PMID: 19949363.
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    62. Whitley RJ. Incomplete financial disclosures in an editorial, clinical crossroads, and reply letter related to herpes zoster. JAMA. 2010 Feb 24; 303(8):733-4. PMID: 20103745.
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    63. Prichard MN, Quenelle DC, Hartline CB, Harden EA, Jefferson G, Frederick SL, Daily SL, Whitley RJ, Tiwari KN, Maddry JA, Secrist JA, Kern ER. Inhibition of herpesvirus replication by 5-substituted 4'-thiopyrimidine nucleosides. Antimicrob Agents Chemother. 2009 Dec; 53(12):5251-8. PMID: 19770274.
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    64. Oliver SE, Cloud GA, Sánchez PJ, Demmler GJ, Dankner W, Shelton M, Jacobs RF, Vaudry W, Pass RF, Soong SJ, Whitley RJ, Kimberlin DW. Neurodevelopmental outcomes following ganciclovir therapy in symptomatic congenital cytomegalovirus infections involving the central nervous system. J Clin Virol. 2009 Dec; 46 Suppl 4:S22-6. PMID: 19766534.
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    65. Whitley RJ. A 70-year-old woman with shingles: review of herpes zoster. JAMA. 2009 Jul 01; 302(1):73-80. PMID: 19491172.
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    66. James SH, Kimberlin DW, Whitley RJ. Antiviral therapy for herpesvirus central nervous system infections: neonatal herpes simplex virus infection, herpes simplex encephalitis, and congenital cytomegalovirus infection. Antiviral Res. 2009 Sep; 83(3):207-13. PMID: 19414035.
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    67. Nassetta L, Kimberlin D, Whitley R. Treatment of congenital cytomegalovirus infection: implications for future therapeutic strategies. J Antimicrob Chemother. 2009 May; 63(5):862-7. PMID: 19287011.
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    68. Whitley RJ, Gnann JW. Herpes zoster in the age of focused immunosuppressive therapy. JAMA. 2009 Feb 18; 301(7):774-5. PMID: 19224757.
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    69. Markert JM, Liechty PG, Wang W, Gaston S, Braz E, Karrasch M, Nabors LB, Markiewicz M, Lakeman AD, Palmer CA, Parker JN, Whitley RJ, Gillespie GY. Phase Ib trial of mutant herpes simplex virus G207 inoculated pre-and post-tumor resection for recurrent GBM. Mol Ther. 2009 Jan; 17(1):199-207. PMID: 18957964.
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    70. Levitsky J, Duddempudi AT, Lakeman FD, Whitley RJ, Luby JP, Lee WM, Fontana RJ, Blei AT, Ison MG. Detection and diagnosis of herpes simplex virus infection in adults with acute liver failure. Liver Transpl. 2008 Oct; 14(10):1498-504. PMID: 18825709.
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    71. Griffiths P, Whitley R, Snydman DR, Singh N, Boeckh M. Contemporary management of cytomegalovirus infection in transplant recipients: guidelines from an IHMF workshop, 2007. Herpes. 2008 Oct; 15(1):4-12. PMID: 18983762.
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    72. Tunkel AR, Glaser CA, Bloch KC, Sejvar JJ, Marra CM, Roos KL, Hartman BJ, Kaplan SL, Scheld WM, Whitley RJ. The management of encephalitis: clinical practice guidelines by the Infectious Diseases Society of America. Clin Infect Dis. 2008 Aug 01; 47(3):303-27. PMID: 18582201.
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    73. Monto AS, Whitley RJ. Seasonal and pandemic influenza: a 2007 update on challenges and solutions. Clin Infect Dis. 2008 Apr 01; 46(7):1024-31. PMID: 18444819.
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    74. Kimberlin DW, Acosta EP, Sánchez PJ, Sood S, Agrawal V, Homans J, Jacobs RF, Lang D, Romero JR, Griffin J, Cloud GA, Lakeman FD, Whitley RJ. Pharmacokinetic and pharmacodynamic assessment of oral valganciclovir in the treatment of symptomatic congenital cytomegalovirus disease. J Infect Dis. 2008 Mar 15; 197(6):836-45. PMID: 18279073.
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    75. Whitley R. The new age of molecular diagnostics for microbial agents. N Engl J Med. 2008 Mar 06; 358(10):988-9. PMID: 18256386.
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    76. Gardella C, Handsfield HH, Whitley R. Neonatal herpes - the forgotten perinatal infection. Sex Transm Dis. 2008 Jan; 35(1):22-4. PMID: 18157063.
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    77. Dworkin RH, Gnann JW, Oaklander AL, Raja SN, Schmader KE, Whitley RJ. Diagnosis and assessment of pain associated with herpes zoster and postherpetic neuralgia. J Pain. 2008 Jan; 9(1 Suppl 1):S37-44. PMID: 18166464.
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    78. Whitley RJ. Therapy of herpes virus infections in children. Adv Exp Med Biol. 2008; 609:216-32. PMID: 18193668.
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    79. Whitley RJ. The role of oseltamivir in the treatment and prevention of influenza in children. Expert Opin Drug Metab Toxicol. 2007 Oct; 3(5):755-67. PMID: 17916060.
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    80. Whitley R, Davis EA, Suppapanya N. Incidence of neonatal herpes simplex virus infections in a managed-care population. Sex Transm Dis. 2007 Sep; 34(9):704-8. PMID: 17413535.
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    81. Breuer J, Whitley R. Varicella zoster virus: natural history and current therapies of varicella and herpes zoster. Herpes. 2007 Sep; 14 Suppl 2:25-9. PMID: 17939892.
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    82. Whitley RJ, Gnann JW. The incidence and severity of herpes simplex encephalitis in Sweden, 1990-2001. Clin Infect Dis. 2007 Oct 01; 45(7):881-2. PMID: 17806054.
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    83. Parker SD, Rottinghaus ST, Zajac AJ, Yue L, Hunter E, Whitley RJ, Parker JN. HIV-1(89.6) Gag expressed from a replication competent HSV-1 vector elicits persistent cellular immune responses in mice. Vaccine. 2007 Sep 17; 25(37-38):6764-73. PMID: 17706843.
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    84. Patel R, Stanberry L, Whitley RJ. Review of recent HSV recurrent-infection treatment studies. Herpes. 2007 Jun; 14(1):23-6. PMID: 17848215.
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    85. Gilbert S, Corey L, Cunningham A, Malkin JE, Stanberry L, Whitley R, Spruance S. An update on short-course intermittent and prevention therapies for herpes labialis. Herpes. 2007 Jun; 14 Suppl 1:13A-18A. PMID: 17877887.
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    86. Rottinghaus ST, Whitley RJ. Current non-AIDS antiviral chemotherapy. Expert Rev Anti Infect Ther. 2007 Apr; 5(2):217-30. PMID: 17402837.
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    87. Kimberlin DW, Whitley RJ. Varicella-zoster vaccine for the prevention of herpes zoster. N Engl J Med. 2007 Mar 29; 356(13):1338-43. PMID: 17392303.
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    88. Acosta EP, Brundage RC, King JR, Sánchez PJ, Sood S, Agrawal V, Homans J, Jacobs RF, Lang D, Romero JR, Griffin J, Cloud G, Whitley R, Kimberlin DW. Ganciclovir population pharmacokinetics in neonates following intravenous administration of ganciclovir and oral administration of a liquid valganciclovir formulation. Clin Pharmacol Ther. 2007 Jun; 81(6):867-72. PMID: 17392728.
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    89. Dworkin RH, Johnson RW, Breuer J, Gnann JW, Levin MJ, Backonja M, Betts RF, Gershon AA, Haanpaa ML, McKendrick MW, Nurmikko TJ, Oaklander AL, Oxman MN, Pavan-Langston D, Petersen KL, Rowbotham MC, Schmader KE, Stacey BR, Tyring SK, van Wijck AJ, Wallace MS, Wassilew SW, Whitley RJ. Recommendations for the management of herpes zoster. Clin Infect Dis. 2007 Jan 01; 44 Suppl 1:S1-26. PMID: 17143845.
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    90. Spruance S, Aoki FY, Tyring S, Stanberry L, Whitley R, Hamed K. Short-course therapy for recurrent genital herpes and herpes labialis. J Fam Pract. 2007 Jan; 56(1):30-6. PMID: 17217895.
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    91. Boeckh M, Englund J, Li Y, Miller C, Cross A, Fernandez H, Kuypers J, Kim H, Gnann J, Whitley R. Randomized controlled multicenter trial of aerosolized ribavirin for respiratory syncytial virus upper respiratory tract infection in hematopoietic cell transplant recipients. Clin Infect Dis. 2007 Jan 15; 44(2):245-9. PMID: 17173225.
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    92. Garcia-Sastre A, Whitley RJ. Lessons learned from reconstructing the 1918 influenza pandemic. J Infect Dis. 2006 Nov 01; 194 Suppl 2:S127-32. PMID: 17163385.
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    93. Whitley RJ, Bartlett J, Hayden FG, Pavia AT, Tapper M, Monto AS. Seasonal and pandemic influenza: recommendations for preparedness in the United States. J Infect Dis. 2006 Nov 01; 194 Suppl 2:S155-61. PMID: 17163389.
      View in: PubMed
    94. Whitley RJ, Monto AS. Seasonal and pandemic influenza preparedness: a global threat. J Infect Dis. 2006 Nov 01; 194 Suppl 2:S65-9. PMID: 17163390.
      View in: PubMed
    95. Markert JM, Parker JN, Buchsbaum DJ, Grizzle WE, Gillespie GY, Whitley RJ. Oncolytic HSV-1 for the treatment of brain tumours. Herpes. 2006 Nov; 13(3):66-71. PMID: 17147910.
      View in: PubMed
    96. Whitley RJ, Monto AS. Prevention and treatment of influenza in high-risk groups: children, pregnant women, immunocompromised hosts, and nursing home residents. J Infect Dis. 2006 Nov 01; 194 Suppl 2:S133-8. PMID: 17163386.
      View in: PubMed
    97. Shalabi M, Whitley RJ. Recurrent benign lymphocytic meningitis. Clin Infect Dis. 2006 Nov 01; 43(9):1194-7. PMID: 17029141.
      View in: PubMed
    98. Guffey MB, Parker JN, Luckett WS, Gillespie GY, Meleth S, Whitley RJ, Markert JM. Engineered herpes simplex virus expressing bacterial cytosine deaminase for experimental therapy of brain tumors. Cancer Gene Ther. 2007 Jan; 14(1):45-56. PMID: 16990846.
      View in: PubMed
    99. Shah AC, Price KH, Parker JN, Samuel SL, Meleth S, Cassady KA, Gillespie GY, Whitley RJ, Markert JM. Serial passage through human glioma xenografts selects for a Deltagamma134.5 herpes simplex virus type 1 mutant that exhibits decreased neurotoxicity and prolongs survival of mice with experimental brain tumors. J Virol. 2006 Aug; 80(15):7308-15. PMID: 16840311.
      View in: PubMed
    100. Whitley R. New approaches to the therapy of HSV infections. Herpes. 2006 Aug; 13(2):53-5. PMID: 16895657.
      View in: PubMed
    101. Desmond RA, Accortt NA, Talley L, Villano SA, Soong SJ, Whitley RJ. Enteroviral meningitis: natural history and outcome of pleconaril therapy. Antimicrob Agents Chemother. 2006 Jul; 50(7):2409-14. PMID: 16801419.
      View in: PubMed
    102. Whitley R, Diaz-Mitoma F, Hamed K. Single-day famciclovir therapy for recurrent genital herpes. Curr Med Res Opin. 2006 Jul; 22(7):1307-10. PMID: 16834829.
      View in: PubMed
    103. Whitley RJ. Herpes simplex encephalitis: adolescents and adults. Antiviral Res. 2006 Sep; 71(2-3):141-8. PMID: 16675036.
      View in: PubMed
    104. Jester PM, Tilden SJ, Li Y, Whitley RJ, Sullender WM. Regulatory challenges: lessons from recent West Nile virus trials in the United States. Contemp Clin Trials. 2006 Jun; 27(3):254-9. PMID: 16603417.
      View in: PubMed
    105. Andrews WW, Kimberlin DF, Whitley R, Cliver S, Ramsey PS, Deeter R. Valacyclovir therapy to reduce recurrent genital herpes in pregnant women. Am J Obstet Gynecol. 2006 Mar; 194(3):774-81. PMID: 16522412.
      View in: PubMed
    106. Sizemore JM, Lakeman F, Whitley R, Hughes A, Hook EW. The spectrum of genital herpes simplex virus infection in men attending a sexually transmitted disease clinic. J Infect Dis. 2006 Apr 01; 193(7):905-11. PMID: 16518750.
      View in: PubMed
    107. Parker JN, Pfister LA, Quenelle D, Gillespie GY, Markert JM, Kern ER, Whitley RJ. Genetically engineered herpes simplex viruses that express IL-12 or GM-CSF as vaccine candidates. Vaccine. 2006 Mar 06; 24(10):1644-52. PMID: 16243413.
      View in: PubMed
    108. Handsfield HH, Waldo AB, Brown ZA, Corey L, Drucker JL, Ebel CW, Leone PA, Stanberry LR, Whitley RJ. Neonatal herpes should be a reportable disease. Sex Transm Dis. 2005 Sep; 32(9):521-5. PMID: 16118598.
      View in: PubMed
    109. Sizemore JM, Lakeman F, Whitley R, Hughes A, Hook EW. Historical correlates of genital herpes simplex virus type 2 infection in men attending an STD clinic. Sex Transm Infect. 2005 Aug; 81(4):303-5. PMID: 16061535.
      View in: PubMed
    110. Davis GL, Nelson DR, Terrault N, Pruett TL, Schiano TD, Fletcher CV, Sapan CV, Riser LN, Li Y, Whitley RJ, Gnann JW. A randomized, open-label study to evaluate the safety and pharmacokinetics of human hepatitis C immune globulin (Civacir) in liver transplant recipients. Liver Transpl. 2005 Aug; 11(8):941-9. PMID: 16035063.
      View in: PubMed
    111. Hellums EK, Markert JM, Parker JN, He B, Perbal B, Roizman B, Whitley RJ, Langford CP, Bharara S, Gillespie GY. Increased efficacy of an interleukin-12-secreting herpes simplex virus in a syngeneic intracranial murine glioma model. Neuro Oncol. 2005 Jul; 7(3):213-24. PMID: 16053696.
      View in: PubMed
    112. Whitley RJ. Changing dynamics of varicella-zoster virus infections in the 21st century: the impact of vaccination. J Infect Dis. 2005 Jun 15; 191(12):1999-2001. PMID: 15897983.
      View in: PubMed
    113. Parker JN, Meleth S, Hughes KB, Gillespie GY, Whitley RJ, Markert JM. Enhanced inhibition of syngeneic murine tumors by combinatorial therapy with genetically engineered HSV-1 expressing CCL2 and IL-12. Cancer Gene Ther. 2005 Apr; 12(4):359-68. PMID: 15678154.
      View in: PubMed
    114. Whitley RJ, Lakeman FD. Human herpesvirus 6 infection of the central nervous system: is it just a case of mistaken association? Clin Infect Dis. 2005 Mar 15; 40(6):894-5. PMID: 15736027.
      View in: PubMed
    115. Whitley RJ, Kimberlin DW. Herpes simplex encephalitis: children and adolescents. Semin Pediatr Infect Dis. 2005 Jan; 16(1):17-23. PMID: 15685145.
      View in: PubMed
    116. Kimberlin DW, Whitley RJ. Neonatal herpes: what have we learned. Semin Pediatr Infect Dis. 2005 Jan; 16(1):7-16. PMID: 15685144.
      View in: PubMed
    117. Bradford RD, Cloud G, Lakeman AD, Boppana S, Kimberlin DW, Jacobs R, Demmler G, Sanchez P, Britt W, Soong SJ, Whitley RJ. Detection of cytomegalovirus (CMV) DNA by polymerase chain reaction is associated with hearing loss in newborns with symptomatic congenital CMV infection involving the central nervous system. J Infect Dis. 2005 Jan 15; 191(2):227-33. PMID: 15609232.
      View in: PubMed
    118. Mertz GJ, Miedzinski L, Goade D, Pavia AT, Hjelle B, Hansbarger CO, Levy H, Koster FT, Baum K, Lindemulder A, Wang W, Riser L, Fernandez H, Whitley RJ. Placebo-controlled, double-blind trial of intravenous ribavirin for the treatment of hantavirus cardiopulmonary syndrome in North America. Clin Infect Dis. 2004 Nov 01; 39(9):1307-13. PMID: 15494907.
      View in: PubMed
    119. Tunkel AR, Hartman BJ, Kaplan SL, Kaufman BA, Roos KL, Scheld WM, Whitley RJ. Practice guidelines for the management of bacterial meningitis. Clin Infect Dis. 2004 Nov 01; 39(9):1267-84. PMID: 15494903.
      View in: PubMed
    120. Whitley RJ. Commentary: Ch'ien LT, Cannon NJ, Charamella LJ, et al. effect of adenine arabinoside on severe herpesvirus hominis infections in man: preliminary report. J Infect Dis 1973; 128:658-63. J Infect Dis. 2004 Oct 01; 190(7):1360-7. PMID: 15346350.
      View in: PubMed
    121. Ch'ien LT, Cannon NJ, Charamella LJ, Dismukes WE, Whitley RJ, Buchanan RA, Alford CA. Effect of adenine arabinoside on severe Herpesvirus hominis infections in man. 1973. J Infect Dis. 2004 Oct 01; 190(7):1362-7. PMID: 15452921.
      View in: PubMed
    122. Sacks SL, Griffiths PD, Corey L, Cohen C, Cunningham A, Dusheiko GM, Self S, Spruance S, Stanberry LR, Wald A, Whitley RJ. Lessons from HIV and hepatitis viruses. Antiviral Res. 2004 Aug; 63 Suppl 1:S11-8. PMID: 15450381.
      View in: PubMed
    123. Sacks SL, Griffiths PD, Corey L, Cohen C, Cunningham A, Dusheiko GM, Self S, Spruance S, Stanberry LR, Wald A, Whitley RJ. HSV-2 transmission. Antiviral Res. 2004 Aug; 63 Suppl 1:S27-35. PMID: 15450383.
      View in: PubMed
    124. Sacks SL, Griffiths PD, Corey L, Cohen C, Cunningham A, Dusheiko GM, Self S, Spruance S, Stanberry LR, Wald A, Whitley RJ. Introduction: Is viral shedding a surrogate marker for transmission of genital herpes? Antiviral Res. 2004 Aug; 63 Suppl 1:S3-9. PMID: 15450380.
      View in: PubMed
    125. Sacks SL, Griffiths PD, Corey L, Cohen C, Cunningham A, Dusheiko GM, Self S, Spruance S, Stanberry LR, Wald A, Whitley RJ. HSV shedding. Antiviral Res. 2004 Aug; 63 Suppl 1:S19-26. PMID: 15450382.
      View in: PubMed
    126. Whitley RJ. Cytomegalovirus and HIV: inextricably entwined pathogens. Lancet. 2004 Jun 26; 363(9427):2101-2. PMID: 15220028.
      View in: PubMed
    127. Whitley R. Neonatal herpes simplex virus infection. Curr Opin Infect Dis. 2004 Jun; 17(3):243-6. PMID: 15166828.
      View in: PubMed
    128. Whitley RJ. Congenital cytomegalovirus infection: epidemiology and treatment. Adv Exp Med Biol. 2004; 549:155-60. PMID: 15250528.
      View in: PubMed
    129. DeMets D, Califf R, Dixon D, Ellenberg S, Fleming T, Held P, Julian D, Kaplan R, Levine R, Neaton J, Packer M, Pocock S, Rockhold F, Seto B, Siegel J, Snapinn S, Stump D, Temple R, Whitley R. Issues in regulatory guidelines for data monitoring committees. Clin Trials. 2004; 1(2):162-9. PMID: 16281888.
      View in: PubMed
    130. Kimberlin DW, Lin CY, Sánchez PJ, Demmler GJ, Dankner W, Shelton M, Jacobs RF, Vaudry W, Pass RF, Kiell JM, Soong SJ, Whitley RJ. Effect of ganciclovir therapy on hearing in symptomatic congenital cytomegalovirus disease involving the central nervous system: a randomized, controlled trial. J Pediatr. 2003 Jul; 143(1):16-25. PMID: 12915819.
      View in: PubMed
    131. Abzug MJ, Cloud G, Bradley J, Sánchez PJ, Romero J, Powell D, Lepow M, Mani C, Capparelli EV, Blount S, Lakeman F, Whitley RJ, Kimberlin DW. Double blind placebo-controlled trial of pleconaril in infants with enterovirus meningitis. Pediatr Infect Dis J. 2003 Apr; 22(4):335-41. PMID: 12690273.
      View in: PubMed
    132. Whitley RJ. Smallpox: a potential agent of bioterrorism. Antiviral Res. 2003 Jan; 57(1-2):7-12. PMID: 12615298.
      View in: PubMed
    133. Advani SJ, Weichselbaum RR, Whitley RJ, Roizman B. Friendly fire: redirecting herpes simplex virus-1 for therapeutic applications. Clin Microbiol Infect. 2002 Sep; 8(9):551-63. PMID: 12427216.
      View in: PubMed
    134. Gnann JW, Whitley RJ. Clinical practice. Herpes zoster. N Engl J Med. 2002 Aug 01; 347(5):340-6. PMID: 12151472.
      View in: PubMed
    135. Whitley RJ, Roizman B. Herpes simplex viruses: is a vaccine tenable? J Clin Invest. 2002 Jul; 110(2):145-51. PMID: 12122103.
      View in: PubMed
    136. Desmond RA, Weiss HL, Arani RB, Soong SJ, Wood MJ, Fiddian PA, Gnann JW, Whitley RJ. Clinical applications for change-point analysis of herpes zoster pain. J Pain Symptom Manage. 2002 Jun; 23(6):510-6. PMID: 12067775.
      View in: PubMed
    137. Whitley RJ. Herpes Simplex Virus in Children. Curr Treat Options Neurol. 2002 May; 4(3):231-237. PMID: 11931730.
      View in: PubMed
    138. Whitley RJ, Gnann JW. Viral encephalitis: familiar infections and emerging pathogens. Lancet. 2002 Feb 09; 359(9305):507-13. PMID: 11853816.
      View in: PubMed
    139. Chung SM, Advani SJ, Bradley JD, Kataoka Y, Vashistha K, Yan SY, Markert JM, Gillespie GY, Whitley RJ, Roizman B, Weichselbaum RR. The use of a genetically engineered herpes simplex virus (R7020) with ionizing radiation for experimental hepatoma. Gene Ther. 2002 Jan; 9(1):75-80. PMID: 11850725.
      View in: PubMed
    140. Whitley RJ. Herpes simplex virus infection. Semin Pediatr Infect Dis. 2002 Jan; 13(1):6-11. PMID: 12118847.
      View in: PubMed
    141. Abramson JS, Baker CJ, Fisher MC, Gerber MA, Meissner HC, Murray DL, Overturf GD, Prober CG, Rennels MB, Saari TN, Weiner LB, Whitley RJ, Pickering LK. Prevention of hepatitis B in adolescents. Pediatrics. 2001 Dec; 108(6):1392. PMID: 11731676.
      View in: PubMed
    142. Arani RB, Soong SJ, Weiss HL, Wood MJ, Fiddian PA, Gnann JW, Whitley R. Phase specific analysis of herpes zoster associated pain data: a new statistical approach. Stat Med. 2001 Aug 30; 20(16):2429-39. PMID: 11512133.
      View in: PubMed
    143. Kimberlin DW, Lin CY, Jacobs RF, Powell DA, Corey L, Gruber WC, Rathore M, Bradley JS, Diaz PS, Kumar M, Arvin AM, Gutierrez K, Shelton M, Weiner LB, Sleasman JW, de Sierra TM, Weller S, Soong SJ, Kiell J, Lakeman FD, Whitley RJ. Safety and efficacy of high-dose intravenous acyclovir in the management of neonatal herpes simplex virus infections. Pediatrics. 2001 Aug; 108(2):230-8. PMID: 11483782.
      View in: PubMed
    144. Kimberlin DW, Lin CY, Jacobs RF, Powell DA, Frenkel LM, Gruber WC, Rathore M, Bradley JS, Diaz PS, Kumar M, Arvin AM, Gutierrez K, Shelton M, Weiner LB, Sleasman JW, de Sierra TM, Soong SJ, Kiell J, Lakeman FD, Whitley RJ. Natural history of neonatal herpes simplex virus infections in the acyclovir era. Pediatrics. 2001 Aug; 108(2):223-9. PMID: 11483781.
      View in: PubMed
    145. Whitley RJ, Roizman B. Herpes simplex virus infections. Lancet. 2001 May 12; 357(9267):1513-8. PMID: 11377626.
      View in: PubMed
    146. Markert JM, Parker JN, Gillespie GY, Whitley RJ. Genetically engineered human herpes simplex virus in the treatment of brain tumours. Herpes. 2001 Mar; 8(1):17-22. PMID: 11867012.
      View in: PubMed
    147. Roizman B, Whitley RJ. The nine ages of herpes simplex virus. Herpes. 2001 Mar; 8(1):23-7. PMID: 11867013.
      View in: PubMed
    148. Whitley RJ, Hayden FG, Reisinger KS, Young N, Dutkowski R, Ipe D, Mills RG, Ward P. Oral oseltamivir treatment of influenza in children. Pediatr Infect Dis J. 2001 Feb; 20(2):127-33. PMID: 11224828.
      View in: PubMed
    149. Whitley RJ, Miller RL. Immunologic approach to herpes simplex virus. Viral Immunol. 2001; 14(2):111-8. PMID: 11398806.
      View in: PubMed
    150. Whitley RJ. Editorial: Our Evolving Knowledge of Herpesviruses. Herpes. 2000 Oct; 7(3):59. PMID: 11867003.
      View in: PubMed
    151. Parker JN, Gillespie GY, Love CE, Randall S, Whitley RJ, Markert JM. Engineered herpes simplex virus expressing IL-12 in the treatment of experimental murine brain tumors. Proc Natl Acad Sci U S A. 2000 Feb 29; 97(5):2208-13. PMID: 10681459.
      View in: PubMed
    152. Markert JM, Gillespie GY, Weichselbaum RR, Roizman B, Whitley RJ. Genetically engineered HSV in the treatment of glioma: a review. Rev Med Virol. 2000 Jan-Feb; 10(1):17-30. PMID: 10654002.
      View in: PubMed
    153. Whitley RJ, Gnann JW. Herpes zoster: focus on treatment in older adults. Antiviral Res. 1999 Dec 31; 44(3):145-54. PMID: 10651066.
      View in: PubMed
    154. Wintergerst U, Gangemi JD, Whitley RJ, Chatterjee S, Kern ER. Effect of recombinant human interferon alpha B/D (rHu-IFN-alpha B/D) in combination with acyclovir in experimental HSV-1 encephalitis. Antiviral Res. 1999 Nov; 44(1):75-8. PMID: 10588335.
      View in: PubMed
    155. Rotbart HA, McCracken GH, Whitley RJ, Modlin JF, Cascino M, Shah S, Blum D. Clinical significance of enteroviruses in serious summer febrile illnesses of children. Pediatr Infect Dis J. 1999 Oct; 18(10):869-74. PMID: 10530582.
      View in: PubMed
    156. Abramson JS, Baker CJ, Fisher MC, Gerber MA, Meissner HC, Murray DL, Overturf GD, Prober CG, Rennels MB, Saari TN, Weiner LB, Whitley RJ. Possible association of intussusception with rotavirus vaccination. American Academy of Pediatrics. Committee on Infectious Diseases. Pediatrics. 1999 Sep; 104(3 Pt 1):575. PMID: 10469790.
      View in: PubMed
    157. Whitley RJ, Kimberlin DW. Viral encephalitis. Pediatr Rev. 1999 Jun; 20(6):192-8. PMID: 10352040.
      View in: PubMed
    158. Harrison RA, Soong S, Weiss HL, Gnann JW, Whitley RJ. A mixed model for factors predictive of pain in AIDS patients with herpes zoster. J Pain Symptom Manage. 1999 Jun; 17(6):410-7. PMID: 10388246.
      View in: PubMed
    159. Bradley JD, Kataoka Y, Advani S, Chung SM, Arani RB, Gillespie GY, Whitley RJ, Markert JM, Roizman B, Weichselbaum RR. Ionizing radiation improves survival in mice bearing intracranial high-grade gliomas injected with genetically modified herpes simplex virus. Clin Cancer Res. 1999 Jun; 5(6):1517-22. PMID: 10389941.
      View in: PubMed
    160. Advani SJ, Chung SM, Yan SY, Gillespie GY, Markert JM, Whitley RJ, Roizman B, Weichselbaum RR. Replication-competent, nonneuroinvasive genetically engineered herpes virus is highly effective in the treatment of therapy-resistant experimental human tumors. Cancer Res. 1999 May 01; 59(9):2055-8. PMID: 10232586.
      View in: PubMed
    161. Whitley RJ, Holland GN. Cytomegalovirus retinitis--evolving therapies in a new era. N Engl J Med. 1999 Apr 08; 340(14):1109-10. PMID: 10194243.
      View in: PubMed
    162. Martin DF, Dunn JP, Davis JL, Duker JS, Engstrom RE, Friedberg DN, Jaffe GJ, Kuppermann BD, Polis MA, Whitley RJ, Wolitz RA, Benson CA. Use of the ganciclovir implant for the treatment of cytomegalovirus retinitis in the era of potent antiretroviral therapy: recommendations of the International AIDS Society-USA panel. Am J Ophthalmol. 1999 Mar; 127(3):329-39. PMID: 10088745.
      View in: PubMed
    163. Whitley RJ, Gnann JW. Therapeutic approaches to the management of herpes zoster. Adv Exp Med Biol. 1999; 458:159-65. PMID: 10549388.
      View in: PubMed
    164. Whitley RJ. Approaches to the treatment of varicella-zoster virus infections. Contrib Microbiol. 1999; 3:158-72. PMID: 10599529.
      View in: PubMed
    165. Whitley RJ, Weiss HL, Soong SJ, Gnann JW. Herpes zoster: risk categories for persistent pain. J Infect Dis. 1999 Jan; 179(1):9-15. PMID: 9841816.
      View in: PubMed
    166. Yoshida M, Yamada M, Tsukazaki T, Chatterjee S, Lakeman FD, Nii S, Whitley RJ. Comparison of antiviral compounds against human herpesvirus 6 and 7. Antiviral Res. 1998 Dec; 40(1-2):73-84. PMID: 9864048.
      View in: PubMed
    167. Whitley RJ, Shukla S, Crooks RJ. The identification of risk factors associated with persistent pain following herpes zoster. J Infect Dis. 1998 Nov; 178 Suppl 1:S71-5. PMID: 9852979.
      View in: PubMed
    168. Kimberlin DW, Whitley RJ. Human herpesvirus-6: neurologic implications of a newly-described viral pathogen. J Neurovirol. 1998 Oct; 4(5):474-85. PMID: 9839645.
      View in: PubMed
    169. Kimberlin DF, Weller S, Whitley RJ, Andrews WW, Hauth JC, Lakeman F, Miller G. Pharmacokinetics of oral valacyclovir and acyclovir in late pregnancy. Am J Obstet Gynecol. 1998 Oct; 179(4):846-51. PMID: 9790357.
      View in: PubMed
    170. Whitley R. Sexually transmitted diseases. Lancet. 1998 Aug 22; 352(9128):651. PMID: 9746048.
      View in: PubMed
    171. Domingues RB, Lakeman FD, Mayo MS, Whitley RJ. Application of competitive PCR to cerebrospinal fluid samples from patients with herpes simplex encephalitis. J Clin Microbiol. 1998 Aug; 36(8):2229-34. PMID: 9665997.
      View in: PubMed
    172. Dunkel EC, Scheer DI, Zhu Q, Whitley RJ, Schaffer PA, Pavan-Langston D, Whitely RJ. Retraction: A rabbit model for human cytomeglovirus--induced chorioretinal disease (J Infect Dis 1993;168:336-44). J Infect Dis. 1998 Jun; 177(6):1778. PMID: 9634358.
      View in: PubMed
    173. Whitley RJ, Jacobson MA, Friedberg DN, Holland GN, Jabs DA, Dieterich DT, Hardy WD, Polis MA, Deutsch TA, Feinberg J, Spector SA, Walmsley S, Drew WL, Powderly WG, Griffiths PD, Benson CA, Kessler HA. Guidelines for the treatment of cytomegalovirus diseases in patients with AIDS in the era of potent antiretroviral therapy: recommendations of an international panel. International AIDS Society-USA. Arch Intern Med. 1998 May 11; 158(9):957-69. PMID: 9588429.
      View in: PubMed
    174. Cohen Stuart JW, Boucher CA, Cooper DA, Galasso GJ, Richman DD, Thomas HC, Whitley RJ. Summary of the III International Consensus Symposium on Combined Antiviral Therapy. Antiviral Res. 1998 May; 38(2):75-93. PMID: 9707371.
      View in: PubMed
    175. Gnann JW, Crumpacker CS, Lalezari JP, Smith JA, Tyring SK, Baum KF, Borucki MJ, Joseph WP, Mertz GJ, Steigbigel RT, Cloud GA, Soong SJ, Sherrill LC, DeHertogh DA, Whitley RJ. Sorivudine versus acyclovir for treatment of dermatomal herpes zoster in human immunodeficiency virus-infected patients: results from a randomized, controlled clinical trial. Collaborative Antiviral Study Group/AIDS Clinical Trials Group, Herpes Zoster Study Group. Antimicrob Agents Chemother. 1998 May; 42(5):1139-45. PMID: 9593141.
      View in: PubMed
    176. Whitley RJ, Kimberlin DW, Roizman B. Herpes simplex viruses. Clin Infect Dis. 1998 Mar; 26(3):541-53; quiz 554-5. PMID: 9524821.
      View in: PubMed
    177. Smith SJ, Li Y, Whitley R, Marion MJ, Partilo S, Carney WP, Brandt-Rauf PW. Molecular epidemiology of p53 protein mutations in workers exposed to vinyl chloride. Am J Epidemiol. 1998 Feb 01; 147(3):302-8. PMID: 9482505.
      View in: PubMed
    178. Andreansky S, He B, van Cott J, McGhee J, Markert JM, Gillespie GY, Roizman B, Whitley RJ. Treatment of intracranial gliomas in immunocompetent mice using herpes simplex viruses that express murine interleukins. Gene Ther. 1998 Jan; 5(1):121-30. PMID: 9536273.
      View in: PubMed
    179. Mennemeyer ST, Cyr LP, Whitley RJ. Antiviral therapy for neonatal herpes simplex virus: a cost-effectiveness analysis. Am J Manag Care. 1997 Oct; 3(10):1551-8. PMID: 10178461.
      View in: PubMed
    180. Whitley R, Castillo N, Hassett JM, Banyas J, Luchette FA. Early tracheostomal healing in rabbits with use of various tracheal incisions. Wound Repair Regen. 1997 Oct-Dec; 5(4):323-8. PMID: 16984442.
      View in: PubMed
    181. Whitley RJ, Cloud G, Gruber W, Storch GA, Demmler GJ, Jacobs RF, Dankner W, Spector SA, Starr S, Pass RF, Stagno S, Britt WJ, Alford C, Soong S, Zhou XJ, Sherrill L, FitzGerald JM, Sommadossi JP. Ganciclovir treatment of symptomatic congenital cytomegalovirus infection: results of a phase II study. National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group. J Infect Dis. 1997 May; 175(5):1080-6. PMID: 9129069.
      View in: PubMed
    182. Andreansky S, Soroceanu L, Flotte ER, Chou J, Markert JM, Gillespie GY, Roizman B, Whitley RJ. Evaluation of genetically engineered herpes simplex viruses as oncolytic agents for human malignant brain tumors. Cancer Res. 1997 Apr 15; 57(8):1502-9. PMID: 9108452.
      View in: PubMed
    183. Rotbart HA, Ahmed A, Hickey S, Dagan R, McCracken GH, Whitley RJ, Modlin JF, Cascino M, O'Connell JF, Menegus MA, Blum D. Diagnosis of enterovirus infection by polymerase chain reaction of multiple specimen types. Pediatr Infect Dis J. 1997 Apr; 16(4):409-11. PMID: 9109145.
      View in: PubMed
    184. Whitley RJ, Kimberlin DW. Treatment of viral infections during pregnancy and the neonatal period. Clin Perinatol. 1997 Mar; 24(1):267-83. PMID: 9099514.
      View in: PubMed
    185. Cassady KA, Whitley RJ. New therapeutic approaches to the alphaherpesvirus infections. J Antimicrob Chemother. 1997 Feb; 39(2):119-28. PMID: 9069530.
      View in: PubMed
    186. Dworkin RH, Carrington D, Cunningham A, Kost RG, Levin MJ, McKendrick MW, Oxman MN, Rentier B, Schmader KE, Tappeiner G, Wassilew SW, Whitley RJ. Assessment of pain in herpes zoster: lessons learned from antiviral trials. Antiviral Res. 1997 Jan; 33(2):73-85. PMID: 9021049.
      View in: PubMed
    187. Kimberlin DW, Lakeman FD, Arvin AM, Prober CG, Corey L, Powell DA, Burchett SK, Jacobs RF, Starr SE, Whitley RJ. Application of the polymerase chain reaction to the diagnosis and management of neonatal herpes simplex virus disease. National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group. J Infect Dis. 1996 Dec; 174(6):1162-7. PMID: 8940204.
      View in: PubMed
    188. van der Meer JT, Drew WL, Bowden RA, Galasso GJ, Griffiths PD, Jabs DA, Katlama C, Spector SA, Whitley RJ. Summary of the International Consensus Symposium on Advances in the Diagnosis, Treatment and Prophylaxis and Cytomegalovirus Infection. Antiviral Res. 1996 Nov; 32(3):119-40. PMID: 8955508.
      View in: PubMed
    189. Andreansky SS, He B, Gillespie GY, Soroceanu L, Markert J, Chou J, Roizman B, Whitley RJ. The application of genetically engineered herpes simplex viruses to the treatment of experimental brain tumors. Proc Natl Acad Sci U S A. 1996 Oct 15; 93(21):11313-8. PMID: 8876132.
      View in: PubMed
    190. Whitley RJ. The past as prelude to the future: history, status, and future of antiviral drugs. Ann Pharmacother. 1996 Sep; 30(9):967-71. PMID: 8876858.
      View in: PubMed
    191. Whitley RJ, Weiss H, Gnann JW, Tyring S, Mertz GJ, Pappas PG, Schleupner CJ, Hayden F, Wolf J, Soong SJ. Acyclovir with and without prednisone for the treatment of herpes zoster. A randomized, placebo-controlled trial. The National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group. Ann Intern Med. 1996 Sep 01; 125(5):376-83. PMID: 8702088.
      View in: PubMed
    192. Zhou XJ, Gruber W, Demmler G, Jacobs R, Reuman P, Adler S, Shelton M, Pass R, Britt B, Trang JM, Whitley RJ, Sommadossi JP. Population pharmacokinetics of ganciclovir in newborns with congenital cytomegalovirus infections. NIAID Collaborative Antiviral Study Group. Antimicrob Agents Chemother. 1996 Sep; 40(9):2202-5. PMID: 8878608.
      View in: PubMed
    193. Wintergerst U, Gangemi JD, Kern ER, Whitley RJ, Chatterjee S. Differential effect of recombinant human and mouse interferons on replication of herpes simplex virus type 1 in mouse cells. Antiviral Res. 1996 Aug; 32(1):27-34. PMID: 8863993.
      View in: PubMed
    194. Whitley RJ. Advances in the management of herpesvirus infections. Introduction. Semin Dermatol. 1996 Jun; 15(2 Suppl 1):1-3. PMID: 8840409.
      View in: PubMed
    195. Whitley RJ. Drug discovery for human immunodeficiency virus infection: conquests and hurdles. J Antimicrob Chemother. 1996 May; 37 Suppl B:151-9. PMID: 8818837.
      View in: PubMed
    196. Yoshida M, Yamada M, Chatterjee S, Lakeman F, Nii S, Whitley RJ. A method for detection of HHV-6 antigens and its use for evaluating antiviral drugs. J Virol Methods. 1996 Apr 26; 58(1-2):137-43. PMID: 8783159.
      View in: PubMed
    197. Kimberlin D, Powell D, Gruber W, Diaz P, Arvin A, Kumar M, Jacobs R, Van Dyke R, Burchett S, Soong SJ, Lakeman A, Whitley R. Administration of oral acyclovir suppressive therapy after neonatal herpes simplex virus disease limited to the skin, eyes and mouth: results of a phase I/II trial. Pediatr Infect Dis J. 1996 Mar; 15(3):247-54. PMID: 8852914.
      View in: PubMed
    198. Kimberlin DW, Whitley RJ. Antiviral resistance: mechanisms, clinical significance, and future implications. J Antimicrob Chemother. 1996 Mar; 37(3):403-21. PMID: 9182098.
      View in: PubMed
    199. Wood MJ, Kay R, Dworkin RH, Soong SJ, Whitley RJ. Oral acyclovir therapy accelerates pain resolution in patients with herpes zoster: a meta-analysis of placebo-controlled trials. Clin Infect Dis. 1996 Feb; 22(2):341-7. PMID: 8838194.
      View in: PubMed
    200. Whitley RJ, Gnann JW, Weiss HL, Soong SJ. Unique clinical trial design: combination acyclovir plus prednisone therapy of localized zoster in the normal host. Antiviral Res. 1996 Jan; 29(1):67-8. PMID: 8721549.
      View in: PubMed
    201. Whitley RJ. Sorivudine: a potent inhibitor of varicella zoster virus replication. Adv Exp Med Biol. 1996; 394:41-4. PMID: 8815706.
      View in: PubMed
    202. Whitley RJ. Sorivudine: a promising drug for the treatment of varicella-zoster virus infection. Neurology. 1995 Dec; 45(12 Suppl 8):S73-5. PMID: 8545030.
      View in: PubMed
    203. DeMets DL, Fleming TR, Whitley RJ, Childress JF, Ellenberg SS, Foulkes M, Mayer KH, O'Fallon J, Pollard RB, Rahal JJ, et al. The data and safety monitoring board and acquired immune deficiency syndrome (AIDS) clinical trials. Control Clin Trials. 1995 Dec; 16(6):408-21. PMID: 8720018.
      View in: PubMed
    204. Whitley RJ, Gnann JW. Herpes zoster in patients with human immunodeficiency virus infection--an ever-expanding spectrum of disease. Clin Infect Dis. 1995 Oct; 21(4):989-90. PMID: 8645853.
      View in: PubMed
    205. McCullers JA, Lakeman FD, Whitley RJ. Human herpesvirus 6 is associated with focal encephalitis. Clin Infect Dis. 1995 Sep; 21(3):571-6. PMID: 8527546.
      View in: PubMed
    206. Stewart JA, Reef SE, Pellett PE, Corey L, Whitley RJ. Herpesvirus infections in persons infected with human immunodeficiency virus. Clin Infect Dis. 1995 Aug; 21 Suppl 1:S114-20. PMID: 8547499.
      View in: PubMed
    207. Kimberlin DW, Spector SA, Hill EL, Biron KK, Hay AJ, Mayers DL, Whitley RJ. Assays for antiviral drug resistance. Antiviral Res. 1995 Apr; 26(4):403-13. PMID: 7574542.
      View in: PubMed
    208. Kimberlin DW, Crumpacker CS, Straus SE, Biron KK, Drew WL, Hayden FG, McKinlay M, Richman DD, Whitley RJ. Antiviral resistance in clinical practice. Antiviral Res. 1995 Apr; 26(4):423-38. PMID: 7574544.
      View in: PubMed
    209. Kimberlin DW, Couch RB, Galasso GJ, Richman DD, Whitley RJ. Research initiatives in studies of antiviral resistance and consensus points and recommendations. Antiviral Res. 1995 Apr; 26(4):439-52. PMID: 7574545.
      View in: PubMed
    210. Kimberlin DW, Kern ER, Sidwell RW, North TW, Whitley RJ. Models of antiviral resistance. Antiviral Res. 1995 Apr; 26(4):415-22. PMID: 7574543.
      View in: PubMed
    211. Lakeman FD, Whitley RJ. Diagnosis of herpes simplex encephalitis: application of polymerase chain reaction to cerebrospinal fluid from brain-biopsied patients and correlation with disease. National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group. J Infect Dis. 1995 Apr; 171(4):857-63. PMID: 7706811.
      View in: PubMed
    212. Kimberlin DW, Whitley RJ. Antiviral resistance--an emerging problem. Antiviral Res. 1995 Apr; 26(4):365-8. PMID: 7574540.
      View in: PubMed
    213. Kimberlin DW, Coen DM, Biron KK, Cohen JI, Lamb RA, McKinlay M, Emini EA, Whitley RJ. Molecular mechanisms of antiviral resistance. Antiviral Res. 1995 Apr; 26(4):369-401. PMID: 7574541.
      View in: PubMed
    214. Chambers R, Gillespie GY, Soroceanu L, Andreansky S, Chatterjee S, Chou J, Roizman B, Whitley RJ. Comparison of genetically engineered herpes simplex viruses for the treatment of brain tumors in a scid mouse model of human malignant glioma. Proc Natl Acad Sci U S A. 1995 Feb 28; 92(5):1411-5. PMID: 7877992.
      View in: PubMed
    215. Whitley RJ, Lakeman F. Herpes simplex virus infections of the central nervous system: therapeutic and diagnostic considerations. Clin Infect Dis. 1995 Feb; 20(2):414-20. PMID: 7742450.
      View in: PubMed
    216. Gangopadhyay NN, Whitley RJ, Chatterjee S. A rapid protein A binding radioimmunoassay for the evaluation of antiviral agents. J Virol Methods. 1994 Jul; 48(2-3):273-9. PMID: 7527404.
      View in: PubMed
    217. Whitley RJ. Neonatal herpes simplex virus infections: is there a role for immunoglobulin in disease prevention and therapy? Pediatr Infect Dis J. 1994 May; 13(5):432-8; discussion 438-9. PMID: 8072834.
      View in: PubMed
    218. Whitley RJ. Herpes simplex virus infections of women and their offspring: implications for a developed society. Proc Natl Acad Sci U S A. 1994 Mar 29; 91(7):2441-7. PMID: 8146137.
      View in: PubMed
    219. Whitley RJ. Prospects for vaccination against herpes simplex virus. Pediatr Ann. 1993 Dec; 22(12):726, 729-32. PMID: 8139874.
      View in: PubMed
    220. Saag MS, Emini EA, Laskin OL, Douglas J, Lapidus WI, Schleif WA, Whitley RJ, Hildebrand C, Byrnes VW, Kappes JC, et al. A short-term clinical evaluation of L-697,661, a non-nucleoside inhibitor of HIV-1 reverse transcriptase. L-697,661 Working Group. N Engl J Med. 1993 Oct 07; 329(15):1065-72. PMID: 7690462.
      View in: PubMed
    221. Norrby SR, Whitley RJ. Evaluation of new anti-infective drugs for the treatment of infection with human immunodeficiency virus. The European Working Party of the European Society of Clinical Microbiology and Infectious Diseases. Clin Infect Dis. 1993 Oct; 17(4):794-801. PMID: 8268368.
      View in: PubMed
    222. Dunkel EC, de Freitas D, Scheer DI, Siegel ML, Zhu Q, Whitley RJ, Schaffer PA, Pavan-Langston D. A rabbit model for human cytomegalovirus-induced chorioretinal disease. J Infect Dis. 1993 Aug; 168(2):336-44. PMID: 8393056.
      View in: PubMed
    223. Mena W, Royal S, Pass RF, Whitley RJ, Philips JB. Diabetes insipidus associated with symptomatic congenital cytomegalovirus infection. J Pediatr. 1993 Jun; 122(6):911-3. PMID: 8388948.
      View in: PubMed
    224. Whitley RJ, Kern ER, Chatterjee S, Chou J, Roizman B. Replication, establishment of latency, and induced reactivation of herpes simplex virus gamma 1 34.5 deletion mutants in rodent models. J Clin Invest. 1993 Jun; 91(6):2837-43. PMID: 8390490.
      View in: PubMed
    225. Sarkar S, Koga J, Whitley RJ, Chatterjee S. Antiviral effect of the extract of culture medium of Lentinus edodes mycelia on the replication of herpes simplex virus type 1. Antiviral Res. 1993 Apr; 20(4):293-303. PMID: 8387258.
      View in: PubMed
    226. Whitley RJ. Neonatal herpes simplex virus infections. J Med Virol. 1993; Suppl 1:13-21. PMID: 8245879.
      View in: PubMed
    227. Whitley RJ. Antiviral therapy: the time has come. J Med Virol. 1993; Suppl 1:1. PMID: 8245872.
      View in: PubMed
    228. Prober CG, Corey L, Brown ZA, Hensleigh PA, Frenkel LM, Bryson YJ, Whitley RJ, Arvin AM. The management of pregnancies complicated by genital infections with herpes simplex virus. Clin Infect Dis. 1992 Dec; 15(6):1031-8. PMID: 1457634.
      View in: PubMed
    229. McCracken GH, Sande MA, Lentnek A, Whitley RJ, Scheld WM. Evaluation of new anti-infective drugs for the treatment of acute bacterial meningitis. Infectious Diseases Society of America and the Food and Drug Administration. Clin Infect Dis. 1992 Nov; 15 Suppl 1:S182-8. PMID: 1477228.
      View in: PubMed
    230. Lentnek A, Sande MA, Whitley RJ, McCracken GH, Scheld WM. Evaluation of new anti-infective drugs for the treatment of cryptococcal meningitis. Infectious Diseases Society of America and the Food and Drug Administration. Clin Infect Dis. 1992 Nov; 15 Suppl 1:S189-94. PMID: 1477229.
      View in: PubMed
    231. Whitley RJ, Lentnek A, McCracken GH, Sande MA, Scheld WM. Evaluation of new anti-infective drugs for the treatment of viral encephalitis. Infectious Diseases Society of America and the Food and Drug Administration. Clin Infect Dis. 1992 Nov; 15 Suppl 1:S195-9. PMID: 1477230.
      View in: PubMed
    232. Sande MA, Whitley RJ, McCracken GH, Lentnek A, Scheld WM. Evaluation of new anti-infective drugs for the treatment of toxoplasma encephalitis. Infectious Diseases Society of America and the Food and Drug Administration. Clin Infect Dis. 1992 Nov; 15 Suppl 1:S200-5. PMID: 1477231.
      View in: PubMed
    233. Perl TM, Haugen TH, Pfaller MA, Hollis R, Lakeman AD, Whitley RJ, Nicholson D, Hunter GA, Wenzel RP. Transmission of herpes simplex virus type 1 infection in an intensive care unit. Ann Intern Med. 1992 Oct 01; 117(7):584-6. PMID: 1524332.
      View in: PubMed
    234. Whitley RJ, Gnann JW. Acyclovir: a decade later. N Engl J Med. 1992 Sep 10; 327(11):782-9. PMID: 1288525.
      View in: PubMed
    235. Chatterjee S, Burns P, Whitley RJ, Kern ER. Effect of (S)-1-[(3-hydroxy-2-phosphonyl methoxy) propyl] cytosine on the replication and morphogenesis of herpes simplex virus type 1. Antiviral Res. 1992 Sep; 19(3):181-92. PMID: 1332603.
      View in: PubMed
    236. Whitley RJ. Neonatal herpes simplex virus infections: pathogenesis and therapy. Pathol Biol (Paris). 1992 Sep; 40(7):729-34. PMID: 1336158.
      View in: PubMed
    237. Whitley RJ. Therapeutic approaches to varicella-zoster virus infections. J Infect Dis. 1992 Aug; 166 Suppl 1:S51-7. PMID: 1378081.
      View in: PubMed
    238. Balfour HH, Rotbart HA, Feldman S, Dunkle LM, Feder HM, Prober CG, Hayden GF, Steinberg S, Whitley RJ, Goldberg L, et al. Acyclovir treatment of varicella in otherwise healthy adolescents. The Collaborative Acyclovir Varicella Study Group. J Pediatr. 1992 Apr; 120(4 Pt 1):627-33. PMID: 1313098.
      View in: PubMed
    239. Whitley RJ, Gnann JW, Hinthorn D, Liu C, Pollard RB, Hayden F, Mertz GJ, Oxman M, Soong SJ. Disseminated herpes zoster in the immunocompromised host: a comparative trial of acyclovir and vidarabine. The NIAID Collaborative Antiviral Study Group. J Infect Dis. 1992 Mar; 165(3):450-5. PMID: 1538151.
      View in: PubMed
    240. Rodu B, Tate AL, Lakeman AF, Mattingly G, Russell CM, Whitley RJ. Prevalence of herpes simplex virus antibodies in dental students. J Dent Educ. 1992 Mar; 56(3):206-8. PMID: 1315348.
      View in: PubMed
    241. Whitley RJ, Meignier B. Herpes simplex vaccines. Biotechnology. 1992; 20:223-54. PMID: 1318135.
      View in: PubMed
    242. Sánchez-Martínez D, Schmid DS, Whittington W, Brown D, Reeves WC, Chatterjee S, Whitley RJ, Pellett PE. Evaluation of a test based on baculovirus-expressed glycoprotein G for detection of herpes simplex virus type-specific antibodies. J Infect Dis. 1991 Dec; 164(6):1196-9. PMID: 1659601.
      View in: PubMed
    243. Nielsen LN, Whitley RJ, Chatterjee S. Apical expression of herpes simplex virus type 2 glycoproteins in human neuroblastoma cells. Virology. 1991 Dec; 185(2):908-10. PMID: 1660208.
      View in: PubMed
    244. Dunkle LM, Arvin AM, Whitley RJ, Rotbart HA, Feder HM, Feldman S, Gershon AA, Levy ML, Hayden GF, McGuirt PV, et al. A controlled trial of acyclovir for chickenpox in normal children. N Engl J Med. 1991 Nov 28; 325(22):1539-44. PMID: 1944438.
      View in: PubMed
    245. Whitley RJ. Herpes simplex virus infections of the central nervous system. Encephalitis and neonatal herpes. Drugs. 1991 Sep; 42(3):406-27. PMID: 1720381.
      View in: PubMed
    246. Saag MS, Crain MJ, Decker WD, Campbell-Hill S, Robinson S, Brown WE, Leuther M, Whitley RJ, Hahn BH, Shaw GM. High-level viremia in adults and children infected with human immunodeficiency virus: relation to disease stage and CD4+ lymphocyte levels. J Infect Dis. 1991 Jul; 164(1):72-80. PMID: 1676046.
      View in: PubMed
    247. Gnann JW, Whitley RJ. Natural history and treatment of varicella-zoster in high-risk populations. J Hosp Infect. 1991 Jun; 18 Suppl A:317-29. PMID: 1679798.
      View in: PubMed
    248. Co MS, Deschamps M, Whitley RJ, Queen C. Humanized antibodies for antiviral therapy. Proc Natl Acad Sci U S A. 1991 Apr 01; 88(7):2869-73. PMID: 1849279.
      View in: PubMed
    249. Whitley R, Arvin A, Prober C, Burchett S, Corey L, Powell D, Plotkin S, Starr S, Alford C, Connor J, et al. A controlled trial comparing vidarabine with acyclovir in neonatal herpes simplex virus infection. Infectious Diseases Collaborative Antiviral Study Group. N Engl J Med. 1991 Feb 14; 324(7):444-9. PMID: 1988829.
      View in: PubMed
    250. Whitley R, Arvin A, Prober C, Corey L, Burchett S, Plotkin S, Starr S, Jacobs R, Powell D, Nahmias A, et al. Predictors of morbidity and mortality in neonates with herpes simplex virus infections. The National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group. N Engl J Med. 1991 Feb 14; 324(7):450-4. PMID: 1988830.
      View in: PubMed
    251. Soong SJ, Watson NE, Caddell GR, Alford CA, Whitley RJ. Use of brain biopsy for diagnostic evaluation of patients with suspected herpes simplex encephalitis: a statistical model and its clinical implications. NIAID Collaborative Antiviral Study Group. J Infect Dis. 1991 Jan; 163(1):17-22. PMID: 1984464.
      View in: PubMed
    252. Chou J, Kern ER, Whitley RJ, Roizman B. Mapping of herpes simplex virus-1 neurovirulence to gamma 134.5, a gene nonessential for growth in culture. Science. 1990 Nov 30; 250(4985):1262-6. PMID: 2173860.
      View in: PubMed
    253. Meignier B, Martin B, Whitley RJ, Roizman B. In vivo behavior of genetically engineered herpes simplex viruses R7017 and R7020. II. Studies in immunocompetent and immunosuppressed owl monkeys (Aotus trivirgatus). J Infect Dis. 1990 Aug; 162(2):313-21. PMID: 2165104.
      View in: PubMed
    254. Whitley RJ. Viral encephalitis. N Engl J Med. 1990 Jul 26; 323(4):242-50. PMID: 2195341.
      View in: PubMed
    255. Gordon B, Selnes OA, Hart J, Hanley DF, Whitley RJ. Long-term cognitive sequelae of acyclovir-treated herpes simplex encephalitis. Arch Neurol. 1990 Jun; 47(6):646-7. PMID: 2346392.
      View in: PubMed
    256. Whitley RJ. Chickenpox: where do we stand with treatment? J Pediatr. 1990 Apr; 116(4):587. PMID: 2319406.
      View in: PubMed
    257. Chatterjee S, Nishimuro S, Whitley RJ. Expression of HSV-1 glycoproteins in tunicamycin-treated monkey kidney cells. Biochem Biophys Res Commun. 1990 Mar 30; 167(3):1139-45. PMID: 2157426.
      View in: PubMed
    258. Whitley RJ. Reference values in pediatric medicine. Mayo Clin Proc. 1990 Mar; 65(3):431-5. PMID: 2314124.
      View in: PubMed
    259. Rowley AH, Whitley RJ, Lakeman FD, Wolinsky SM. Rapid detection of herpes-simplex-virus DNA in cerebrospinal fluid of patients with herpes simplex encephalitis. Lancet. 1990 Feb 24; 335(8687):440-1. PMID: 1968171.
      View in: PubMed
    260. Whitley RJ, Middlebrooks M, Gnann JW. Acyclovir: the past ten years. Adv Exp Med Biol. 1990; 278:243-53. PMID: 1963040.
      View in: PubMed
    261. Whitley RJ, Connell J, Markiewicz MA, Sommadossi JP. Novel pharmacological strategies in the treatment of life-threatening cytomegalovirus infections. Clinical experience with continuous infusion 9-(1,3-dihydroxy-2-propoxymethyl) guanine. Ann N Y Acad Sci. 1990; 616:452-60. PMID: 1964031.
      View in: PubMed
    262. Canessa A, Chatterjee S, Whitley RJ, Prasthofer EF, Grossi CE, Tilden AB. Individual NK cell clones lyse both tumor cell targets and herpes simplex virus-infected fibroblasts in the absence of interferon. Viral Immunol. 1990; 3(3):217-24. PMID: 1701642.
      View in: PubMed
    263. Whitley RJ. Varicella-zoster virus infections: chronic disease in the immunocompromised host: evidence for persistent excretion of virus. Pediatr Infect Dis J. 1989 Sep; 8(9):584-5. PMID: 2552389.
      View in: PubMed
    264. Chatterjee S, Koga J, Whitley RJ. A role for herpes simplex virus type 1 glycoprotein E in induction of cell fusion. J Gen Virol. 1989 Aug; 70 ( Pt 8):2157-62. PMID: 2549184.
      View in: PubMed
    265. Whitley RJ, Cobbs CG, Alford CA, Soong SJ, Hirsch MS, Connor JD, Corey L, Hanley DF, Levin M, Powell DA. Diseases that mimic herpes simplex encephalitis. Diagnosis, presentation, and outcome. NIAD Collaborative Antiviral Study Group. JAMA. 1989 Jul 14; 262(2):234-9. PMID: 2544743.
      View in: PubMed
    266. Cauda R, Laghi V, Tumbarello M, Ortona L, Whitley RJ. Immunological alterations associated with recurrent herpes simplex genitalis. Clin Immunol Immunopathol. 1989 May; 51(2):294-302. PMID: 2539283.
      View in: PubMed
    267. Chatterjee S, Whitley RJ. Effect of recombinant hybrid human interferon on replication and morphogenesis of HSV-1 in monkey cells. Virus Res. 1989 Jan; 12(1):33-41. PMID: 2541580.
      View in: PubMed
    268. Baldwin S, Whitley RJ. Intrauterine herpes simplex virus infection. Teratology. 1989 Jan; 39(1):1-10. PMID: 2655150.
      View in: PubMed
    269. Whitley RJ. Neonatal herpes simplex virus infections. Clin Perinatol. 1988 Dec; 15(4):903-16. PMID: 3061706.
      View in: PubMed
    270. Kahlon J, Whitley RJ. Antibody response of the newborn after herpes simplex virus infection. J Infect Dis. 1988 Nov; 158(5):925-33. PMID: 2846711.
      View in: PubMed
    271. Peacock JE, Kaplowitz LG, Sparling PF, Durack DT, Gnann JW, Whitley RJ, Lovett M, Bryson YJ, Klein RJ, Friedman-Kien AE, et al. Intravenous acyclovir therapy of first episodes of genital herpes: a multicenter double-blind, placebo-controlled trial. Am J Med. 1988 Sep; 85(3):301-6. PMID: 3046350.
      View in: PubMed
    272. Whitley RJ. Herpes simplex virus infections of the central nervous system. A review. Am J Med. 1988 Aug 29; 85(2A):61-7. PMID: 3044095.
      View in: PubMed
    273. Grimaldi LM, Roos RP, Manservigi R, Spear PG, Lakeman FD, Whitley RJ. An isoelectric focusing study in herpes simplex virus encephalitis. Ann Neurol. 1988 Aug; 24(2):227-32. PMID: 3140713.
      View in: PubMed
    274. Whitley RJ, Corey L, Arvin A, Lakeman FD, Sumaya CV, Wright PF, Dunkle LM, Steele RW, Soong SJ, Nahmias AJ, et al. Changing presentation of herpes simplex virus infection in neonates. J Infect Dis. 1988 Jul; 158(1):109-16. PMID: 3392410.
      View in: PubMed
    275. Reichman RC, Oakes D, Bonnez W, Greisberger C, Tyring S, Miller L, Whitley R, Carveth H, Weidner M, Krueger G, et al. Treatment of condyloma acuminatum with three different interferons administered intralesionally. A double-blind, placebo-controlled trial. Ann Intern Med. 1988 May; 108(5):675-9. PMID: 3358568.
      View in: PubMed
    276. Baldwin S, Stagno S, Odrezin GT, Kelly DR, Whitley RJ. Isolated Cryptococcus neoformans osteomyelitis in an immunocompetent child. Pediatr Infect Dis J. 1988 Apr; 7(4):289-92. PMID: 3368272.
      View in: PubMed
    277. Bell DS, Clements RS, Cutter GR, Whitley RJ. Condylomata acuminata in IDDM. Diabetes Care. 1988 Mar; 11(3):295-6. PMID: 3416688.
      View in: PubMed
    278. Whitley RJ. Ganciclovir--have we established clinical value in the treatment of cytomegalovirus infections? Ann Intern Med. 1988 Mar; 108(3):452-4. PMID: 2829680.
      View in: PubMed
    279. Whitley RJ. The frustrations of treating herpes simplex virus infections of the central nervous system. JAMA. 1988 Feb 19; 259(7):1067. PMID: 3339805.
      View in: PubMed
    280. Schlitt M, Bucher AP, Stroop WG, Pindak F, Bastian FO, Jennings RA, Lakeman AD, Whitley RJ. Neurovirulence in an experimental focal herpes encephalitis: relationship to observed seizures. Brain Res. 1988 Feb 09; 440(2):293-8. PMID: 2833994.
      View in: PubMed
    281. Metcalf JF, Chatterjee S, Koga J, Whitley RJ. Protection against herpetic ocular disease by immunotherapy with monoclonal antibodies to herpes simplex virus glycoproteins. Intervirology. 1988; 29(1):39-49. PMID: 2838428.
      View in: PubMed
    282. Corey L, Whitley RJ, Stone EF, Mohan K. Difference between herpes simplex virus type 1 and type 2 neonatal encephalitis in neurological outcome. Lancet. 1988 Jan 2-9; 1(8575-6):1-4. PMID: 2891886.
      View in: PubMed
    283. Whitley RJ. Antiviral treatment of a serious herpes simplex infection: encephalitis. J Am Acad Dermatol. 1988 Jan; 18(1 Pt 2):209-11. PMID: 3339144.
      View in: PubMed
    284. Whitley RJ. Natural history and pathogenesis of neonatal herpes simplex virus infections. Ann N Y Acad Sci. 1988; 549:103-17. PMID: 3067635.
      View in: PubMed
    285. Hanley DF, Johnson RT, Whitley RJ. Yes, brain biopsy should be a prerequisite for herpes simplex encephalitis treatment. Arch Neurol. 1987 Dec; 44(12):1289-90. PMID: 3675261.
      View in: PubMed
    286. Petty BG, Whitley RJ, Liao S, Krasny HC, Rocco LE, Davis LG, Lietman PS. Pharmacokinetics and tolerance of desciclovir, a prodrug of acyclovir, in healthy human volunteers. Antimicrob Agents Chemother. 1987 Sep; 31(9):1317-22. PMID: 3674844.
      View in: PubMed
    287. Tyring SK, Cauda R, Baron S, Whitley RJ. Condyloma acuminatum: epidemiological, clinical and therapeutic aspects. Eur J Epidemiol. 1987 Sep; 3(3):209-15. PMID: 3308509.
      View in: PubMed
    288. Cauda R, Prasthofer EF, Grossi CE, Whitley RJ, Pass RF. Congenital cytomegalovirus: immunological alterations. J Med Virol. 1987 Sep; 23(1):41-9. PMID: 2824678.
      View in: PubMed
    289. Cauda R, Tyring SK, Grossi CE, Tilden AB, Hatch KD, Sams WM, Baron S, Whitley RJ. Patients with condyloma acuminatum exhibit decreased interleukin-2 and interferon gamma production and depressed natural killer activity. J Clin Immunol. 1987 Jul; 7(4):304-11. PMID: 3112173.
      View in: PubMed
    290. Baldwin S, Stagno S, Whitley R. Transfusion-associated viral infections. Curr Probl Pediatr. 1987 Jul; 17(7):391-443. PMID: 2824131.
      View in: PubMed
    291. Lakeman FD, Koga J, Whitley RJ. Detection of antigen to herpes simplex virus in cerebrospinal fluid from patients with herpes simplex encephalitis. J Infect Dis. 1987 Jun; 155(6):1172-8. PMID: 3033092.
      View in: PubMed
    292. Longnecker R, Chatterjee S, Whitley RJ, Roizman B. Identification of a herpes simplex virus 1 glycoprotein gene within a gene cluster dispensable for growth in cell culture. Proc Natl Acad Sci U S A. 1987 Jun; 84(12):4303-7. PMID: 3035578.
      View in: PubMed
    293. Cauda R, Grossi CE, Whitley RJ, Tilden AB. Analysis of immune function in herpes zoster patients: demonstration and characterization of suppressor cells. J Immunol. 1987 Feb 15; 138(4):1229-33. PMID: 3027175.
      View in: PubMed
    294. Barnes DW, Whitley RJ. Antiviral therapy and pulmonary disease. Chest. 1987 Feb; 91(2):246-51. PMID: 3026739.
      View in: PubMed
    295. Metcalf JF, Whitley RJ. Protective immunity against herpetic ocular disease in an outbred mouse model. Curr Eye Res. 1987 Jan; 6(1):167-71. PMID: 3030641.
      View in: PubMed
    296. Brasfield DM, Stagno S, Whitley RJ, Cloud G, Cassell G, Tiller RE. Infant pneumonitis associated with cytomegalovirus, Chlamydia, Pneumocystis, and Ureaplasma: follow-up. Pediatrics. 1987 Jan; 79(1):76-83. PMID: 3025807.
      View in: PubMed
    297. Whitley RJ. Approaches to therapy of viral infections. Adv Pediatr. 1987; 34:89-110. PMID: 2825477.
      View in: PubMed
    298. Whitley RJ, Hutto SC. Therapy of viral infections in children. Adv Pediatr Infect Dis. 1987; 2:35-56. PMID: 2840931.
      View in: PubMed
    299. Cauda R, Prasthofer EF, Tilden AB, Whitley RJ, Grossi CE. T-cell imbalances and NK activity in varicella-zoster virus infections. Viral Immunol. 1987; 1(2):145-52. PMID: 2978454.
      View in: PubMed
    300. Metcalf JF, Koga J, Chatterjee S, Whitley RJ. Passive immunization with monoclonal antibodies against herpes simplex virus glycoproteins protects mice against herpetic ocular disease. Curr Eye Res. 1987 Jan; 6(1):173-7. PMID: 3030642.
      View in: PubMed
    301. Whitley RJ, Alford CA, Hirsch MS, Schooley RT, Luby JP, Aoki FY, Hanley D, Nahmias AJ, Soong SJ. Factors indicative of outcome in a comparative trial of acyclovir and vidarabine for biopsy-proven herpes simplex encephalitis. Infection. 1987; 15 Suppl 1:S3-8. PMID: 3298070.
      View in: PubMed
    302. Kahlon J, Chatterjee S, Lakeman FD, Lee F, Nahmias AJ, Whitley RJ. Detection of antibodies to herpes simplex virus in the cerebrospinal fluid of patients with herpes simplex encephalitis. J Infect Dis. 1987 Jan; 155(1):38-44. PMID: 3025307.
      View in: PubMed
    303. Koga J, Chatterjee S, Whitley RJ. Studies on herpes simplex virus type 1 glycoproteins using monoclonal antibodies. Virology. 1986 Jun; 151(2):385-9. PMID: 3010559.
      View in: PubMed
    304. Tilden AB, Cauda R, Grossi CE, Balch CM, Lakeman AD, Whitley RJ. Demonstration of NK cell-mediated lysis of varicella-zoster virus (VZV)-infected cells: characterization of the effector cells. J Immunol. 1986 Jun 01; 136(11):4243-8. PMID: 3009620.
      View in: PubMed
    305. Cauda R, Chatterjee S, Tilden AB, Grossi CE, Whitley RJ. Replication of varicella zoster virus in Raji cells. Virus Res. 1986 Jun; 4(4):337-42. PMID: 3014780.
      View in: PubMed
    306. Whitley RJ. Neonatal herpes simplex virus infections. Presentation and management. J Reprod Med. 1986 May; 31(5 Suppl):426-32. PMID: 3522894.
      View in: PubMed
    307. Lakeman AD, Nahmias AJ, Whitley RJ. Analysis of DNA from recurrent genital herpes simplex virus isolates by restriction endonuclease digestion. Sex Transm Dis. 1986 Apr-Jun; 13(2):61-6. PMID: 3012807.
      View in: PubMed
    308. Schlitt M, Lakeman AD, Wilson ER, To A, Acoff RW, Harsh GR, Whitley RJ. A rabbit model of focal herpes simplex encephalitis. J Infect Dis. 1986 Apr; 153(4):732-5. PMID: 3005433.
      View in: PubMed
    309. Kahlon J, Lakeman FD, Ackermann M, Whitley RJ. Human antibody response to herpes simplex virus-specific polypeptides after primary and recurrent infection. J Clin Microbiol. 1986 Apr; 23(4):725-30. PMID: 2422204.
      View in: PubMed
    310. Barnes DW, Whitley RJ. CNS diseases associated with varicella zoster virus and herpes simplex virus infection. Pathogenesis and current therapy. Neurol Clin. 1986 Feb; 4(1):265-83. PMID: 3523204.
      View in: PubMed
    311. Whitley RJ, Alford CA, Hirsch MS, Schooley RT, Luby JP, Aoki FY, Hanley D, Nahmias AJ, Soong SJ. Vidarabine versus acyclovir therapy in herpes simplex encephalitis. N Engl J Med. 1986 Jan 16; 314(3):144-9. PMID: 3001520.
      View in: PubMed
    312. Whitley RJ. Herpesvirus infections in the immunocompromised host: diagnosis and management. Adv Exp Med Biol. 1986; 202:95-118. PMID: 3024455.
      View in: PubMed
    313. Schlitt MJ, Morawetz RB, Bonnin JM, Zeiger HE, Whitley RJ. Brain biopsy for encephalitis. Clin Neurosurg. 1986; 33:591-602. PMID: 3539442.
      View in: PubMed
    314. Stagno S, Whitley RJ. Herpesvirus infections of pregnancy. Part II: Herpes simplex virus and varicella-zoster virus infections. N Engl J Med. 1985 Nov 21; 313(21):1327-30. PMID: 3903503.
      View in: PubMed
    315. Stagno S, Whitley RJ. Herpesvirus infections of pregnancy. Part I: Cytomegalovirus and Epstein-Barr virus infections. N Engl J Med. 1985 Nov 14; 313(20):1270-4. PMID: 2997607.
      View in: PubMed
    316. Chatterjee S, Hunter E, Whitley R. Effect of cloned human interferons on protein synthesis and morphogenesis of herpes simplex virus. J Virol. 1985 Nov; 56(2):419-25. PMID: 2997465.
      View in: PubMed
    317. Schlitt M, Lakeman FD, Whitley RJ. Psychosis and herpes simplex encephalitis. South Med J. 1985 Nov; 78(11):1347-50. PMID: 4071143.
      View in: PubMed
    318. McCann WP, Hall LM, Siler W, Barton N, Whitley RJ. High-pressure liquid chromatographic methods for determining arabinosyladenine-5'-monophosphate, arabinosyladenine, and arabinosylhypoxanthine in plasma and urine. Antimicrob Agents Chemother. 1985 Aug; 28(2):265-73. PMID: 2423028.
      View in: PubMed
    319. Whitley RJ. Parvovirus infection: chance and investigation. N Engl J Med. 1985 Jul 11; 313(2):111-2. PMID: 2987694.
      View in: PubMed
    320. Whitley RJ. Therapy for human herpesvirus infections. A perspective. Ala J Med Sci. 1985 Apr; 22(2):193-207. PMID: 2988359.
      View in: PubMed
    321. Whitley RJ, Soong SJ, Alford CA, Hirsch MS, Schooley R, Oxman MN, Connor JD, Betts R, Dolin R, Reichman RC. Design of therapeutic studies in herpes simplex encephalitis. Lancet. 1985 Feb 02; 1(8423):284-5. PMID: 2857352.
      View in: PubMed
    322. Whitley RJ, Nahmias AJ. Therapeutic challenges of neonatal herpes simplex virus infection. Scand J Infect Dis Suppl. 1985; 47:97-106. PMID: 3868027.
      View in: PubMed
    323. Garcia JH, Sekar BC, Whitley RJ. Medical pathology conference. Headache, fever, abnormal behavior, and dysphasia in an elderly man. Ala J Med Sci. 1984 Oct; 21(4):399-406. PMID: 6507801.
      View in: PubMed
    324. Whitley RJ, Levin M, Barton N, Hershey BJ, Davis G, Keeney RE, Whelchel J, Diethelm AG, Kartus P, Soong SJ. Infections caused by herpes simplex virus in the immunocompromised host: natural history and topical acyclovir therapy. J Infect Dis. 1984 Sep; 150(3):323-9. PMID: 6090539.
      View in: PubMed
    325. Whitley RJ. Treatment of human herpesvirus infections with special reference to encephalitis. J Antimicrob Chemother. 1984 Aug; 14 Suppl A:57-74. PMID: 6092319.
      View in: PubMed
    326. Garcia JH, Colon LE, Whitley RJ, Wilmes FJ. Diagnosis of viral encephalitis by brain biopsy. Semin Diagn Pathol. 1984 May; 1(2):71-81. PMID: 6400632.
      View in: PubMed
    327. Overall JC, Whitley RJ, Yeager AS, McCracken GH, Nelson JD. Prophylactic or anticipatory antiviral therapy for newborns exposed to herpes simplex infection. Pediatr Infect Dis. 1984 May-Jun; 3(3):193-5. PMID: 6539912.
      View in: PubMed
    328. Whitley RJ, Spruance S, Hayden FG, Overall J, Alford CA, Gwaltney JM, Soong SJ. Vidarabine therapy for mucocutaneous herpes simplex virus infections in the immunocompromised host. J Infect Dis. 1984 Jan; 149(1):1-8. PMID: 6693782.
      View in: PubMed
    329. Chatterjee S, Lakeman AD, Whitley RJ, Hunter E. Effect of cloned human interferons on the replication of and cell fusion induced by herpes simplex virus. Virus Res. 1984 Jan; 1(1):81-7. PMID: 6099653.
      View in: PubMed
    330. Dworsky M, Pass RF, Stagno S, Whitley RJ. Therapeutic approaches to the control of cytomegalovirus infections. Birth Defects Orig Artic Ser. 1984; 20(1):345-52. PMID: 6329371.
      View in: PubMed
    331. Whitley RJ, Yeager A, Kartus P, Bryson Y, Connor JD, Alford CA, Nahmias A, Soong SJ. Neonatal herpes simplex virus infection: follow-up evaluation of vidarabine therapy. Pediatrics. 1983 Dec; 72(6):778-85. PMID: 6359047.
      View in: PubMed
    332. Coleman RM, Bailey PD, Whitley RJ, Keyserling H, Nahmias AJ. ELISA for the detection of herpes simplex virus antigens in the cerebrospinal fluid of patients with encephalitis. J Virol Methods. 1983 Sep; 7(3):117-25. PMID: 6315749.
      View in: PubMed
    333. Whitley RJ. Interim summary of mortality in herpes simplex encephalitis and neonatal herpes simplex virus infections: vidarabine versus acyclovir. J Antimicrob Chemother. 1983 Sep; 12 Suppl B:105-12. PMID: 6355046.
      View in: PubMed
    334. Gnann JW, Barton NH, Whitley RJ. Acyclovir: mechanism of action, pharmacokinetics, safety and clinical applications. Pharmacotherapy. 1983 Sep-Oct; 3(5):275-83. PMID: 6359082.
      View in: PubMed
    335. Morawetz RB, Whitley RJ, Murphy DM. Experience with brain biopsy for suspected herpes encephalitis: a review of forty consecutive cases. Neurosurgery. 1983 Jun; 12(6):654-7. PMID: 6308497.
      View in: PubMed
    336. Volpi A, Whitley RJ, Ceballos R, Stagno S, Pereira L. Rapid diagnosis of pneumonia due to cytomegalovirus with specific monoclonal antibodies. J Infect Dis. 1983 Jun; 147(6):1119-20. PMID: 6304205.
      View in: PubMed
    337. Whitley RJ, Crist WM. Management of infections. Pediatr Ann. 1983 Jun; 12(6):445-9. PMID: 6348682.
      View in: PubMed
    338. Whitley RJ, Alford CA. Towards therapy and prevention of herpetic infections. Semin Perinatol. 1983 Jan; 7(1):64-81. PMID: 6302915.
      View in: PubMed
    339. Whitley R, Lakeman AD, Nahmias A, Roizman B. Dna restriction-enzyme analysis of herpes simplex virus isolates obtained from patients with encephalitis. N Engl J Med. 1982 Oct 21; 307(17):1060-2. PMID: 6289100.
      View in: PubMed
    340. Whitley RJ, Soong SJ, Dolin R, Betts R, Linnemann C, Alford CA. Early vidarabine therapy to control the complications of herpes zoster in immunosuppressed patients. N Engl J Med. 1982 Oct 14; 307(16):971-5. PMID: 7110300.
      View in: PubMed
    341. Furlow TW, Whitley RJ, Wilmes FJ. Repeated suppression of Creutzfeldt-Jakob disease with vidarabine. Lancet. 1982 Sep 04; 2(8297):564-5. PMID: 6125725.
      View in: PubMed
    342. Whitley RJ, Blum MR, Barton N, de Miranda P. Pharmacokinetics of acyclovir in humans following intravenous administration. A model for the development of parenteral antivirals. Am J Med. 1982 Jul 20; 73(1A):165-71. PMID: 7102700.
      View in: PubMed
    343. Whitley R, Barton N, Collins E, Whelchel J, Diethelm AG. Mucocutaneous herpes simplex virus infections in immunocompromised patients. A model for evaluation of topical antiviral agents. Am J Med. 1982 Jul 20; 73(1A):236-40. PMID: 7048915.
      View in: PubMed
    344. Whitley R, Hilty M, Haynes R, Bryson Y, Connor JD, Soong SJ, Alford CA. Vidarabine therapy of varicella in immunosuppressed patients. J Pediatr. 1982 Jul; 101(1):125-31. PMID: 7045313.
      View in: PubMed
    345. Nahmias AJ, Whitley RJ, Visintine AN, Takei Y, Alford CA. Herpes simplex virus encephalitis: laboratory evaluations and their diagnostic significance. J Infect Dis. 1982 Jun; 145(6):829-36. PMID: 6282983.
      View in: PubMed
    346. Alford CA, Dolin R, Hirsch MS, Karchmer AW, Whitley RJ. Herpes simplex encephalitis and clinical trial design. Lancet. 1982 May 01; 1(8279):1013. PMID: 6122821.
      View in: PubMed
    347. Whitley RJ, Alford CA. Herpesvirus infections in childhood: diagnostic dilemmas and therapy. Pediatr Infect Dis. 1982 Mar-Apr; 1(2):81-4. PMID: 7177907.
      View in: PubMed
    348. Whitley RJ, Soong SJ, Linneman C, Liu C, Pazin G, Alford CA. Herpes simplex encephalitis. Clinical Assessment. JAMA. 1982 Jan 15; 247(3):317-20. PMID: 6275134.
      View in: PubMed
    349. Pass RF, Dworsky ME, Whitley RJ, August AM, Stagno S, Alford CA. Specific lymphocyte blastogenic responses in children with cytomegalovirus and herpes simplex virus infections acquired early in infancy. Infect Immun. 1981 Oct; 34(1):166-70. PMID: 6271679.
      View in: PubMed
    350. Whitley RJ, Alford CA. Preventive and therapeutic approaches to the newborn infant with perinatal viral and toxoplasma infections. Clin Perinatol. 1981 Oct; 8(3):591-604. PMID: 6171374.
      View in: PubMed
    351. Stagno S, Brasfield DM, Brown MB, Cassell GH, Pifer LL, Whitley RJ, Tiller RE. Infant pneumonitis associated with cytomegalovirus, Chlamydia, Pneumocystis, and Ureaplasma: a prospective study. Pediatrics. 1981 Sep; 68(3):322-9. PMID: 6269042.
      View in: PubMed
    352. Lee FK, Takei Y, Dannenbarger J, Visintine A, Whitley R, Nahmias A. Rapid detection of viruses in biopsy or autopsy specimens by the pseudoreplica method of electron microscopy. Am J Surg Pathol. 1981 Sep; 5(6):565-72. PMID: 6275724.
      View in: PubMed
    353. Whitley RJ, Alford CA. Antiviral agents: clinical status report. Hosp Pract (Off Ed). 1981 Jul; 16(7):109-21. PMID: 6788666.
      View in: PubMed
    354. Whitley RJ, Soong SJ, Hirsch MS, Karchmer AW, Dolin R, Galasso G, Dunnick JK, Alford CA. Herpes simplex encephalitis: vidarabine therapy and diagnostic problems. N Engl J Med. 1981 Feb 05; 304(6):313-8. PMID: 6255332.
      View in: PubMed
    355. Whitley R. Diagnosis and treatment of herpes simplex encephalitis. Annu Rev Med. 1981; 32:335-40. PMID: 7013672.
      View in: PubMed
    356. Whitley RJ, Tucker BC, Kinkel AW, Barton NH, Pass RF, Whelchel JD, Cobbs CG, Diethelm AG, Buchanan RA. Pharmacology, tolerance, and antiviral activity of vidarabine monophosphate in humans. Antimicrob Agents Chemother. 1980 Nov; 18(5):709-15. PMID: 6160811.
      View in: PubMed
    357. Whitley R, Alford C, Hess F, Buchanan R. Vidarabine: a preliminary review of its pharmacological properties and therapeutic use. Drugs. 1980 Oct; 20(4):267-82. PMID: 6998693.
      View in: PubMed
    358. Whitley RJ, Nahmias AJ, Soong SJ, Galasso GG, Fleming CL, Alford CA. Vidarabine therapy of neonatal herpes simplex virus infection. Pediatrics. 1980 Oct; 66(4):495-501. PMID: 7001331.
      View in: PubMed
    359. Whitley RJ, Nahmias AJ, Visintine AM, Fleming CL, Alford CA. The natural history of herpes simplex virus infection of mother and newborn. Pediatrics. 1980 Oct; 66(4):489-94. PMID: 6253866.
      View in: PubMed
    360. Whitley RJ, Alford CA. Herpes simplex encephalitis: need for accurate diagnosis. JAMA. 1980 Jul 25; 244(4):371-2. PMID: 7392134.
      View in: PubMed
    361. Pass RF, Whitley RJ, Diethelm AG, Whelchel JD, Reynolds DW, Alford CA. Cytomegalovirus infection in patients with renal transplants: potentiation by antithymocyte globulin and an incompatible graft. J Infect Dis. 1980 Jul; 142(1):9-17. PMID: 6249875.
      View in: PubMed
    362. Dworsky M, Whitley R, Alford C. Herpes zoster in early infancy. Am J Dis Child. 1980 Jun; 134(6):618-9. PMID: 7386437.
      View in: PubMed
    363. Buchanan RA, Kinkel AW, Alford CA, Whitley RJ. Plasma levels and urinary excretion of vidarabine after repeated dosing. Clin Pharmacol Ther. 1980 May; 27(5):690-6. PMID: 7371366.
      View in: PubMed
    364. de Miranda P, Whitley RJ, Blum MR, Keeney RE, Barton N, Cocchetto DM, Good S, Hemstreet GP, Kirk LE, Page DA, Elion GB. Acyclovir kinetics after intravenous infusion. Clin Pharmacol Ther. 1979 Dec; 26(6):718-28. PMID: 227639.
      View in: PubMed
    365. Whelchel JD, Pass RF, Diethelm AG, Whitley RJ, Alford CA. Effect of primary and recurrent cytomegalovirus infections upon graft and patient survival after renal transplantation. Transplantation. 1979 Dec; 28(6):443-6. PMID: 229592.
      View in: PubMed
    366. Mazur MH, Whitley RJ, Dolin R. Serum antibody levels as risk factors in the dissemination of herpes zoster. Arch Intern Med. 1979 Dec; 139(12):1341-5. PMID: 229783.
      View in: PubMed
    367. Pass RF, Whitley RJ, Whelchel JD, Diethelm AG, Reynolds DW, Alford CA. Identification of patients with increased risk of infection with herpes simplex virus after renal transplantation. J Infect Dis. 1979 Oct; 140(4):487-92. PMID: 390063.
      View in: PubMed
    368. Whitley RJ, Arvin A, Galasso G, Dunnick J. Distribution of adenine arabinoside and interferon. JAMA. 1979 Sep 21; 242(12):1259-60. PMID: 480535.
      View in: PubMed
    369. Pass RF, Whitley RJ, Diethelm AG, Whelchel JD, Reynolds DW, Alford CA. Outcome of renal transplantation in patients with primary cytomegalovirus infection. Transplant Proc. 1979 Jun; 11(2):1288-90. PMID: 224539.
      View in: PubMed
    370. Whitley RJ, Alford CA. Developmental aspects of adenine arabinoside for parenteral therapy of human herpesvirus infections. Adv Ophthalmol. 1979; 38:288-96. PMID: 230722.
      View in: PubMed
    371. Chen AB, Ben-Porat T, Whitley RJ, Kaplan AS. Purification and characterization of proteins excreted by cells infected with herpes simplex virus and their use in diagnosis. Virology. 1978 Dec; 91(2):234-42. PMID: 217149.
      View in: PubMed
    372. Tucker BA, Doekel RC, Whitley RJ, Dismukes WE. Herpes simplex virus encephalitis: an atypical presentation. South Med J. 1978 Nov; 71(11):1431-3. PMID: 715494.
      View in: PubMed
    373. Whitley RJ, Alford CA. Current status of antiviral chemotherapy. South Med J. 1978 Sep; 71(9):1134-40. PMID: 210524.
      View in: PubMed
    374. Dolin R, Reichman RC, Mazur MH, Whitley RJ. NIH conference. Herpes zoster-varicella infections in immunosuppressed patients. Ann Intern Med. 1978 Sep; 89(3):375-88. PMID: 210697.
      View in: PubMed
    375. Pass RF, Long WK, Whitley RJ, Soong SJ, Diethelm AG, Reynolds DW, Alford CA. Productive infection with cytomegalovirus and herpes simplex virus in renal transplant recipients: role of source of kidney. J Infect Dis. 1978 May; 137(5):556-63. PMID: 207784.
      View in: PubMed
    376. Whitley RJ, Alford CA. Developmental aspects of selected antiviral chemotherapeutic agents. Annu Rev Microbiol. 1978; 32:285-300. PMID: 213011.
      View in: PubMed
    377. Whitley RJ, Soong SJ, Dolin R, Galasso GJ, Ch'ien LT, Alford CA. Adenine arabinoside therapy of biopsy-proved herpes simplex encephalitis. J Med Assoc State Ala. 1977 Sep; 47(3):37-42, 66. PMID: 903726.
      View in: PubMed
    378. Whitley RJ, Soong SJ, Dolin R, Galasso GJ, Ch'ien LT, Alford CA. Adenine arabinoside therapy of biopsy-proved herpes simplex encephalitis. National Institute of Allergy and Infectious Diseases collaborative antiviral study. N Engl J Med. 1977 Aug 11; 297(6):289-94. PMID: 195208.
      View in: PubMed
    379. Whitley RJ, Brasfield D, Reynolds DW, Stagno S, Tiller RE, Alford CA. Protracted pneumonitis in young infants associated with perinatally acquired cytomegaloviral infection. J Pediatr. 1976 Jul; 89(1):16-22. PMID: 180275.
      View in: PubMed
    380. Alford CA, Whitley RJ. Treatment of infections due to Herpesvirus in humans: a critical review of the state of the art. J Infect Dis. 1976 Jun; 133 Suppl:A101-8. PMID: 180191.
      View in: PubMed
    381. Ch'ien LT, Whitley RJ, Alford CA, Galasso GJ. Adenine arabinoside for therapy of herpes zoster in immunosuppressed patients: preliminary results of a collaborative study. J Infect Dis. 1976 Jun; 133 Suppl:A184-91. PMID: 180198.
      View in: PubMed
    382. Whitley RJ, Ch'ien LT, Dolin R, Galasso GJ, Alford CA. Adenine arabinoside therapy of herpes zoster in the immunosuppressed. NIAID collaborative antiviral study. N Engl J Med. 1976 May 27; 294(22):1193-9. PMID: 177866.
      View in: PubMed
    383. Alford CA, Whitley R. Therapy of herpetic infections in man: a status report. Adv Pathobiol. 1976; (5):159-72. PMID: 220853.
      View in: PubMed
    384. Ceballos R, Ch'ien LT, Whitley RJ, Brans YW. Cerebellar hypoplasia in an infant with congenital cytomegalovirus infection. Pediatrics. 1976 Jan; 57(1):155-7. PMID: 174055.
      View in: PubMed
    385. Whitley RJ. The hospital founded in 1838 by W. J. Little. Med Biol Illus. 1975 Nov; 25(4):240-4. PMID: 778507.
      View in: PubMed
    386. Ch'ien LT, Whitley RJ, Nahmias AJ, Lewin EB, Linnemann CC, Frenkel LD, Bellanti JA, Buchanan RA, Alford DA. Antiviral chemotherapy and neonatal herpes simplex virus infecition: a pilot study--experience with adenine arabinoside (ARA-A). Pediatrics. 1975 May; 55(5):678-85. PMID: 165453.
      View in: PubMed
    387. Whitley RJ, Ch'ien LT, Alford CA. Neonatal herpes simplex virus infection. Int Ophthalmol Clin. 1975; 15(4):141-9. PMID: 1225858.
      View in: PubMed
    388. Ch'ien LT, Cannon NJ, Whitley RJ, Diethelm AG, Dismukes WE, Scott CW, Buchanan RA, Alford CA. Effect of adenine arabinoside on cytomegalovirus infections. J Infect Dis. 1974 Jul; 130(1):32-9. PMID: 4366288.
      View in: PubMed
    389. Ch'ien LT, Cannon NJ, Charamella LJ, Dismukes WE, Whitley RJ, Buchanan RA, Alford CA. Effect of adenine arabinoside on severe Herpesvirus hominis infections in man. J Infect Dis. 1973 Nov; 128(5):658-63. PMID: 4358651.
      View in: PubMed
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