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Michael Baxa

TitlePostdoctoral Scholar
InstitutionUniversity of Chicago
DepartmentBiochemistry and Molecular Biology
AddressChicago IL 60637
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Sosnick TR, Baxa MC, Sosnick TR, Baxa MC. Collapse and Protein Folding: Should We Be Surprised That Biothermodynamics Works So Well? Annu Rev Biophys. 2025 May; 54(1):17-34. PMID: 39689264.
      Citations: 1     Fields:    Translation:HumansCells
    2. Zhang N, Sood D, Guo SC, Chen N, Antoszewski A, Marianchuk T, Dey S, Xiao Y, Hong L, Peng X, Baxa M, Partch C, Wang LP, Sosnick TR, Dinner AR, LiWang A. Temperature-dependent fold-switching mechanism of the circadian clock protein KaiB. Proc Natl Acad Sci U S A. 2024 Dec 17; 121(51):e2412327121. PMID: 39671178; PMCID: PMC11665890.
      Citations: 2     Fields:    Translation:Cells
    3. Zhang N, Sood D, Guo SC, Chen N, Antoszewski A, Marianchuk T, Chavan A, Dey S, Xiao Y, Hong L, Peng X, Baxa M, Partch C, Wang LP, Sosnick TR, Dinner AR, LiWang A. Temperature-Dependent Fold-Switching Mechanism of the Circadian Clock Protein KaiB. bioRxiv. 2024 May 21. PMID: 38826295; PMCID: PMC11142059.
      Citations:    
    4. Baxa MC, Lin X, Mukinay CD, Chakravarthy S, Sachleben JR, Antilla S, Hartrampf N, Riback JA, Gagnon IA, Pentelute BL, Clark PL, Sosnick TR. How hydrophobicity, side chains, and salt affect the dimensions of disordered proteins. Protein Sci. 2024 May; 33(5):e4986. PMID: 38607226; PMCID: PMC11010952.
      Citations: 2     Fields:    Translation:Cells
    5. Zmyslowski AM, Baxa MC, Gagnon IA, Sosnick TR. HDX-MS performed on BtuB in E. coli outer membranes delineates the luminal domain's allostery and unfolding upon B12 and TonB binding. Proc Natl Acad Sci U S A. 2022 05 17; 119(20):e2119436119. PMID: 35549554; PMCID: PMC9171809.
      Citations: 12     Fields:    Translation:Cells
    6. Baxa MC, Sosnick TR. Engineered Metal-Binding Sites to Probe Protein Folding Transition States: Psi Analysis. Methods Mol Biol. 2022; 2376:31-63. PMID: 34845602.
      Citations: 1     Fields:    Translation:Cells
    7. Peng X, Baxa M, Faruk N, Sachleben JR, Pintscher S, Gagnon IA, Houliston S, Arrowsmith CH, Freed KF, Rocklin GJ, Sosnick TR. Prediction and Validation of a Protein's Free Energy Surface Using Hydrogen Exchange and (Importantly) Its Denaturant Dependence. J Chem Theory Comput. 2022 Jan 11; 18(1):550-561. PMID: 34936354; PMCID: PMC8757463.
      Citations: 5     Fields:    Translation:Cells
    8. Gates ZP, Baxa MC, Yu W, Riback JA, Li H, Kent SB, Sosnick TR, Roux B. Perplexing cooperative folding and stability of a low-sequence complexity, polyproline 2 protein lacking a hydrophobic core. Proc Natl Acad Sci U S A. 2017 02 28; 114(9):2241-2246. PMID: 28193869; PMCID: PMC5338507.
      Citations: 13     Fields:    Translation:AnimalsCells
    9. Yu W, Baxa MC, Gagnon I, Freed KF, Sosnick TR. Cooperative folding near the downhill limit determined with amino acid resolution by hydrogen exchange. Proc Natl Acad Sci U S A. 2016 Apr 26; 113(17):4747-52. PMID: 27078098; PMCID: PMC4855600.
      Citations: 6     Fields:    Translation:Cells
    10. Baxa MC, Yu W, Adhikari AN, Ge L, Xia Z, Zhou R, Freed KF, Sosnick TR. Even with nonnative interactions, the updated folding transition states of the homologs Proteins G & L are extensive and similar. Proc Natl Acad Sci U S A. 2015 Jul 07; 112(27):8302-7. PMID: 26100906; PMCID: PMC4500205.
      Citations: 10     Fields:    Translation:Cells
    11. Skinner JJ, Yu W, Gichana EK, Baxa MC, Hinshaw JR, Freed KF, Sosnick TR. Benchmarking all-atom simulations using hydrogen exchange. Proc Natl Acad Sci U S A. 2014 Nov 11; 111(45):15975-80. PMID: 25349413; PMCID: PMC4234613.
      Citations: 33     Fields:    Translation:Cells
    12. Baxa MC, Haddadian EJ, Jumper JM, Freed KF, Sosnick TR. Loss of conformational entropy in protein folding calculated using realistic ensembles and its implications for NMR-based calculations. Proc Natl Acad Sci U S A. 2014 Oct 28; 111(43):15396-401. PMID: 25313044; PMCID: PMC4217416.
      Citations: 42     Fields:    Translation:Cells
    13. Sosnick TR, Baxa MC. Revealing what gets buried first in protein folding. Proc Natl Acad Sci U S A. 2013 Oct 15; 110(42):16704-5. PMID: 24096579; PMCID: PMC3801029.
      Citations: 1     Fields:    Translation:Cells
    14. Baxa MC, Haddadian EJ, Jha AK, Freed KF, Sosnick TR. Context and force field dependence of the loss of protein backbone entropy upon folding using realistic denatured and native state ensembles. J Am Chem Soc. 2012 Sep 26; 134(38):15929-36. PMID: 22928488; PMCID: PMC3464005.
      Citations: 10     Fields:    Translation:Cells
    15. Shandiz AT, Baxa MC, Sosnick TR. A "Link-Psi" strategy using crosslinking indicates that the folding transition state of ubiquitin is not very malleable. Protein Sci. 2012 Jun; 21(6):819-27. PMID: 22528473; PMCID: PMC3403417.
      Citations: 5     Fields:    Translation:Cells
    16. Bosco GL, Baxa M, Sosnick TR. Metal binding kinetics of bi-histidine sites used in psi analysis: evidence of high-energy protein folding intermediates. Biochemistry. 2009 Apr 07; 48(13):2950-9. PMID: 19220047; PMCID: PMC3313835.
      Citations: 8     Fields:    
    17. Baxa MC, Freed KF, Sosnick TR. Psi-constrained simulations of protein folding transition states: implications for calculating. J Mol Biol. 2009 Mar 06; 386(4):920-8. PMID: 19244613; PMCID: PMC2742336.
      Citations: 7     Fields:    
    18. Baxa MC, Freed KF, Sosnick TR. Quantifying the structural requirements of the folding transition state of protein A and other systems. J Mol Biol. 2008 Sep 19; 381(5):1362-81. PMID: 18625237; PMCID: PMC2742318.
      Citations: 17     Fields:    
    19. Sosnick TR, Krantz BA, Dothager RS, Baxa M. Characterizing the protein folding transition state using psi analysis. Chem Rev. 2006 May; 106(5):1862-76. PMID: 16683758.
      Citations: 27     Fields:    Translation:Cells
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