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Rochelle Naylor

TitleAssociate Professor
InstitutionUniversity of Chicago
DepartmentPediatrics-Endocrinology
AddressChicago IL 60637
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    Dr. Naylor’s clinical and research expertise are in genetic and atypical forms of diabetes. She is a co-Investigator of the US National Monogenic Diabetes Registry housed at the University of Chicago, an investigator of the rare and atypical diabetes network, or RADIANT study and contributes to the American Diabetes Association Precision Medicine in Diabetes Initiative. Her work addresses barriers to accurate genetic diagnosis of MODY and inequities in who benefits from diabetes precision medicine. She has carried out cost-effectiveness analyses demonstrating the economic value of accurate genetic diagnosis of MODY and ongoing studies seek to clarify best management practices for MODY and support broader implementation of precision medicine in diabetes.

    Collapse Research 
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    K23DK114564     (NAYLOR, ROCHELLE NICOLE)Jul 1, 2017 - Nov 30, 2021
    NIH
    Advancing Recognition and Personalized Genetic Medicine for MODY in a Multi-Ethnic US Population
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Kubota-Mishra E, Huang X, Minard CG, Astudillo M, Refaey A, Montes G, Sisley S, Ram N, Winter WE, Naylor RN, Balasubramanyam A, Redondo MJ, Tosur M, RADIANT Study Group. High Prevalence of A-ß+ Ketosis-Prone Diabetes in Children with Type 2 Diabetes and Diabetic Ketoacidosis at Diagnosis: Evidence from the Rare and Atypical Diabetes Network (RADIANT). Pediatr Diabetes. 2024; 2024. PMID: 38765897; PMCID: PMC11100136.
      Citations:    Fields:    Translation:HumansCells
    2. Balogun WO, Naylor R, Adedokun BO, Ogunniyi A, Olopade OI, Dagogo-Jack SE, Bell GI, Philipson LH. Implementing genetic testing in diabetes: Knowledge, perceptions of healthcare professionals, and barriers in a developing country. Popul Med. 2024 Mar; 6. PMID: 38681897; PMCID: PMC11052599.
      Citations:    
    3. Noohi F, Sundaresan MS, Naylor RN, Ross LF. Investigator and participant expectations for returning non-genetic results: insights from the Rare and Atypical Diabetes Network (RADIANT) study. J Clin Transl Sci. 2023; 7(1):e260. PMID: 38229892; PMCID: PMC10789975.
      Citations:    
    4. Tobias DK, Merino J, Ahmad A, Aiken C, Benham JL, Bodhini D, Clark AL, Colclough K, Corcoy R, Cromer SJ, Duan D, Felton JL, Francis EC, Gillard P, Gingras V, Gaillard R, Haider E, Hughes A, Ikle JM, Jacobsen LM, Kahkoska AR, Kettunen JLT, Kreienkamp RJ, Lim LL, Männistö JME, Massey R, Mclennan NM, Miller RG, Morieri ML, Most J, Naylor RN, Ozkan B, Patel KA, Pilla SJ, Prystupa K, Raghavan S, Rooney MR, Schön M, Semnani-Azad Z, Sevilla-Gonzalez M, Svalastoga P, Takele WW, Tam CH, Thuesen ACB, Tosur M, Wallace AS, Wang CC, Wong JJ, Yamamoto JM, Young K, Amouyal C, Andersen MK, Bonham MP, Chen M, Cheng F, Chikowore T, Chivers SC, Clemmensen C, Dabelea D, Dawed AY, Deutsch AJ, Dickens LT, DiMeglio LA, Dudenhöffer-Pfeifer M, Evans-Molina C, Fernández-Balsells MM, Fitipaldi H, Fitzpatrick SL, Gitelman SE, Goodarzi MO, Grieger JA, Guasch-Ferré M, Habibi N, Hansen T, Huang C, Harris-Kawano A, Ismail HM, Hoag B, Johnson RK, Jones AG, Koivula RW, Leong A, Leung GKW, Libman IM, Liu K, Long SA, Lowe WL, Morton RW, Motala AA, Onengut-Gumuscu S, Pankow JS, Pathirana M, Pazmino S, Perez D, Petrie JR, Powe CE, Quinteros A, Jain R, Ray D, Ried-Larsen M, Saeed Z, Santhakumar V, Kanbour S, Sarkar S, Monaco GSF, Scholtens DM, Selvin E, Sheu WH, Speake C, Stanislawski MA, Steenackers N, Steck AK, Stefan N, Støy J, Taylor R, Tye SC, Ukke GG, Urazbayeva M, Van der Schueren B, Vatier C, Wentworth JM, Hannah W, White SL, Yu G, Zhang Y, Zhou SJ, Beltrand J, Polak M, Aukrust I, de Franco E, Flanagan SE, Maloney KA, McGovern A, Molnes J, Nakabuye M, Njølstad PR, Pomares-Millan H, Provenzano M, Saint-Martin C, Zhang C, Zhu Y, Auh S, de Souza R, Fawcett AJ, Gruber C, Mekonnen EG, Mixter E, Sherifali D, Eckel RH, Nolan JJ, Philipson LH, Brown RJ, Billings LK, Boyle K, Costacou T, Dennis JM, Florez JC, Gloyn AL, Gomez MF, Gottlieb PA, Greeley SAW, Griffin K, Hattersley AT, Hirsch IB, Hivert MF, Hood KK, Josefson JL, Kwak SH, Laffel LM, Lim SS, Loos RJF, Ma RCW, Mathieu C, Mathioudakis N, Meigs JB, Misra S, Mohan V, Murphy R, Oram R, Owen KR, Ozanne SE, Pearson ER, Perng W, Pollin TI, Pop-Busui R, Pratley RE, Redman LM, Redondo MJ, Reynolds RM, Semple RK, Sherr JL, Sims EK, Sweeting A, Tuomi T, Udler MS, Vesco KK, Vilsbøll T, Wagner R, Rich SS, Franks PW. Second international consensus report on gaps and opportunities for the clinical translation of precision diabetes medicine. Nat Med. 2023 Oct; 29(10):2438-2457. PMID: 37794253; PMCID: PMC10735053.
      Citations: 19     Fields:    Translation:Humans
    5. ADA/EASD PMDI, Naylor RN, Patel KA, Kettunen JLT, Männistö JME, Støy J, Beltrand J, Polak M, Vilsbøll T, Greeley SAW, Hattersley AT, Tuomi T. Systematic Review of Treatment of Beta-Cell Monogenic Diabetes. medRxiv. 2023 Sep 22. PMID: 37214872; PMCID: PMC10197799.
      Citations:    
    6. Arosemena M, Salguero MV, Naylor RN, Wroblewski K, Tasali E, Philipson LH. Objective and Subjective Sleep Patterns in Adults With Maturity-Onset Diabetes of the Young (MODY). Diabetes Care. 2023 03 01; 46(3):608-612. PMID: 36637968; PMCID: PMC10090264.
      Citations:    Fields:    Translation:Humans
    7. Tosur M, Gandolfo L, Balasubramanyam A, Naylor RN, Pollin TI, Rasouli N, Cromer SJ, Buse JB, Redondo MJ, RADIANT Study Group. Enrollment of underrepresented racial and ethnic groups in the Rare and Atypical Diabetes Network (RADIANT). J Clin Transl Sci. 2023; 7(1):e47. PMID: 36845305; PMCID: PMC9947614.
      Citations: 1     
    8. Noohi F, Sundaresan MS, Naylor RN, Ross LF. Diagnosis, treatment and disclosure: A qualitative exploration of participant challenges in a Monogenic Diabetes Registry. Genet Med. 2023 04; 25(4):100019. PMID: 36681871; PMCID: PMC10620612.
      Citations:    Fields:    Translation:Humans
    9. Bowden TL, Letourneau-Freiberg LR, Kandasamy B, Sanyoura M, Tian P, Harris AG, Bell GI, Philipson LH, Naylor RN, Greeley SAW. Insight on Diagnosis and Treatment From Over a Decade of Research Through the University of Chicago Monogenic Diabetes Registry. Front Clin Diabetes Healthc. 2021 Nov; 2. PMID: 36330312; PMCID: PMC9629510.
      Citations: 4     
    10. Palmer W, Greeley SAW, Naylor R. The Do-It-Yourself Artificial Pancreas. Pediatr Ann. 2021 Jul; 50(7):e304-e307. PMID: 34264792.
      Citations: 2     Fields:    Translation:Humans
    11. Palmer W, Greeley SAW, Letourneau-Freiberg LR, Naylor RN. Using a Do-It-Yourself Artificial Pancreas: Perspectives from Patients and Diabetes Providers. J Diabetes Sci Technol. 2020 09; 14(5):860-867. PMID: 32680447; PMCID: PMC7753849.
      Citations: 7     Fields:    Translation:Humans
    12. GoodSmith MS, Skandari MR, Huang ES, Naylor RN. The Impact of Biomarker Screening and Cascade Genetic Testing on the Cost-Effectiveness of MODY Genetic Testing. Diabetes Care. 2019 12; 42(12):2247-2255. PMID: 31558549; PMCID: PMC6868460.
      Citations: 11     Fields:    Translation:HumansPHPublic Health
    13. Harris A, Naylor RN. Pediatric Monogenic Diabetes: A Unique Challenge and Opportunity. Pediatr Ann. 2019 Aug 01; 48(8):e319-e325. PMID: 31426100.
      Citations: 1     Fields:    Translation:Humans
    14. Gregory JM, Smith TJ, Slaughter JC, Mason HR, Hughey CC, Smith MS, Kandasamy B, Greeley SAW, Philipson LH, Naylor RN, Letourneau LR, Abumrad NN, Cherrington AD, Moore DJ. Iatrogenic Hyperinsulinemia, Not Hyperglycemia, Drives Insulin Resistance in Type 1 Diabetes as Revealed by Comparison With GCK-MODY (MODY2). Diabetes. 2019 08; 68(8):1565-1576. PMID: 31092478; PMCID: PMC6692813.
      Citations: 22     Fields:    Translation:Humans
    15. Sanyoura M, Letourneau L, Knight Johnson AE, Del Gaudio D, Greeley SAW, Philipson LH, Naylor RN. GCK-MODY in the US Monogenic Diabetes Registry: Description of 27 unpublished variants. Diabetes Res Clin Pract. 2019 May; 151:231-236. PMID: 31063852; PMCID: PMC6544496.
      Citations: 7     Fields:    Translation:Humans
    16. Naylor R. Economics of Genetic Testing for Diabetes. Curr Diab Rep. 2019 03 27; 19(5):23. PMID: 30919097; PMCID: PMC6886700.
      Citations: 11     Fields:    Translation:Humans
    17. Dickens LT, Letourneau LR, Sanyoura M, Greeley SAW, Philipson LH, Naylor RN. Management and pregnancy outcomes of women with GCK-MODY enrolled in the US Monogenic Diabetes Registry. Acta Diabetol. 2019 Apr; 56(4):405-411. PMID: 30535721; PMCID: PMC6468988.
      Citations: 18     Fields:    Translation:Humans
    18. Sanyoura M, Philipson LH, Naylor R. Monogenic Diabetes in Children and Adolescents: Recognition and Treatment Options. Curr Diab Rep. 2018 06 22; 18(8):58. PMID: 29931562; PMCID: PMC6312113.
      Citations: 33     Fields:    Translation:Humans
    19. Dickens LT, Naylor RN. Clinical Management of Women with Monogenic Diabetes During Pregnancy. Curr Diab Rep. 2018 02 15; 18(3):12. PMID: 29450745; PMCID: PMC5908233.
      Citations: 19     Fields:    Translation:Humans
    20. Laiteerapong N, Cooper JM, Skandari MR, Clarke PM, Winn AN, Naylor RN, Huang ES. Individualized Glycemic Control for U.S. Adults With Type 2 Diabetes: A Cost-Effectiveness Analysis. Ann Intern Med. 2018 02 06; 168(3):170-178. PMID: 29230472; PMCID: PMC5989575.
      Citations: 15     Fields:    Translation:Humans
    21. Lanning MS, Carmody D, Szczerbinski L, Letourneau LR, Naylor RN, Greeley SAW. Hypoglycemia in sulfonylurea-treated KCNJ11-neonatal diabetes: Mild-moderate symptomatic episodes occur infrequently but none involving unconsciousness or seizures. Pediatr Diabetes. 2018 05; 19(3):393-397. PMID: 29205704; PMCID: PMC5918230.
      Citations: 12     Fields:    Translation:Humans
    22. Letourneau LR, Carmody D, Wroblewski K, Denson AM, Sanyoura M, Naylor RN, Philipson LH, Greeley SAW. Diabetes Presentation in Infancy: High Risk of Diabetic Ketoacidosis. Diabetes Care. 2017 10; 40(10):e147-e148. PMID: 28779000; PMCID: PMC5606305.
      Citations: 26     Fields:    
    23. Carmody D, Pastore AN, Landmeier KA, Letourneau LR, Martin R, Hwang JL, Naylor RN, Hunter SJ, Msall ME, Philipson LH, Scott MN, Greeley SA. Patients with KCNJ11-related diabetes frequently have neuropsychological impairments compared with sibling controls. Diabet Med. 2016 10; 33(10):1380-6. PMID: 27223594; PMCID: PMC5654490.
      Citations: 16     Fields:    Translation:Humans
    24. Carmody D, Naylor RN, Bell CD, Berry S, Montgomery JT, Tadie EC, Hwang JL, Greeley SA, Philipson LH. GCK-MODY in the US National Monogenic Diabetes Registry: frequently misdiagnosed and unnecessarily treated. Acta Diabetol. 2016 Oct; 53(5):703-8. PMID: 27106716; PMCID: PMC5016218.
      Citations: 37     Fields:    Translation:Humans
    25. Carmody D, Naylor RN, Philipson LH. Insulin dosing in pediatric diabetic ketoacidosis: where to start? JAMA. 2015 Jun 09; 313(22):2274-5. PMID: 26057288.
      Citations:    Fields:    Translation:Humans
    26. Carmody D, Beca FA, Bell CD, Hwang JL, Dickens JT, Devine NA, Mackay DJ, Temple IK, Hays LR, Naylor RN, Philipson LH, Greeley SA. Role of noninsulin therapies alone or in combination in chromosome 6q24-related transient neonatal diabetes: sulfonylurea improves but does not always normalize insulin secretion. Diabetes Care. 2015 Jun; 38(6):e86-7. PMID: 25998302; PMCID: PMC4439531.
      Citations: 12     Fields:    
    27. Carmody D, Lindauer KL, Naylor RN. Adolescent non-adherence reveals a genetic cause for diabetes. Diabet Med. 2015 Jun; 32(6):e20-3. PMID: 25494859; PMCID: PMC4640698.
      Citations: 3     Fields:    Translation:Humans
    28. Thurber BW, Carmody D, Tadie EC, Pastore AN, Dickens JT, Wroblewski KE, Naylor RN, Philipson LH, Greeley SA, United States Neonatal Diabetes Working Group. Age at the time of sulfonylurea initiation influences treatment outcomes in KCNJ11-related neonatal diabetes. Diabetologia. 2015 Jul; 58(7):1430-5. PMID: 25877689; PMCID: PMC4641523.
      Citations: 31     Fields:    Translation:Humans
    29. Carmody D, Bell CD, Hwang JL, Dickens JT, Sima DI, Felipe DL, Zimmer CA, Davis AO, Kotlyarevska K, Naylor RN, Philipson LH, Greeley SA. Sulfonylurea treatment before genetic testing in neonatal diabetes: pros and cons. J Clin Endocrinol Metab. 2014 Dec; 99(12):E2709-14. PMID: 25238204; PMCID: PMC4255121.
      Citations: 25     Fields:    Translation:Humans
    30. Naylor RN, John PM, Winn AN, Carmody D, Greeley SA, Philipson LH, Bell GI, Huang ES. Cost-effectiveness of MODY genetic testing: translating genomic advances into practical health applications. Diabetes Care. 2014; 37(1):202-9. PMID: 24026547; PMCID: PMC3867988.
      Citations: 54     Fields:    Translation:Humans
    31. Greeley SA, Naylor RN, Philipson LH, Bell GI. Neonatal diabetes: an expanding list of genes allows for improved diagnosis and treatment. Curr Diab Rep. 2011 Dec; 11(6):519-32. PMID: 21993633; PMCID: PMC3226065.
      Citations: 47     Fields:    Translation:Humans
    32. Naylor R, Philipson LH. Who should have genetic testing for maturity-onset diabetes of the young? Clin Endocrinol (Oxf). 2011 Oct; 75(4):422-6. PMID: 21521318.
      Citations: 24     Fields:    Translation:Humans
    33. Greeley SA, Naylor RN, Cook LS, Tucker SE, Lipton RB, Philipson LH. Creation of the Web-based University of Chicago Monogenic Diabetes Registry: using technology to facilitate longitudinal study of rare subtypes of diabetes. J Diabetes Sci Technol. 2011 Jul 01; 5(4):879-86. PMID: 21880229; PMCID: PMC3192593.
      Citations: 18     Fields:    Translation:Humans
    34. Naylor RN, Greeley SA, Bell GI, Philipson LH. Genetics and pathophysiology of neonatal diabetes mellitus. J Diabetes Investig. 2011 Jun 05; 2(3):158-69. PMID: 24843477; PMCID: PMC4014912.
      Citations: 30     Fields:    
    35. Greeley SA, Tucker SE, Naylor RN, Bell GI, Philipson LH. Neonatal diabetes mellitus: a model for personalized medicine. Trends Endocrinol Metab. 2010 Aug; 21(8):464-72. PMID: 20434356; PMCID: PMC2914172.
      Citations: 24     Fields:    Translation:HumansAnimals
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