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James P. Zacny

TitleEmeritus/Emerita, Professor (CS)
InstitutionUniversity of Chicago
DepartmentAnesthesia & Critical Care
AddressChicago IL 60637
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Shah HA, Fischer JH, Venepalli NK, Danciu OC, Christian S, Russell MJ, Liu LC, Zacny JP, Dudek AZ. Phase I Study of Aurora A Kinase Inhibitor Alisertib (MLN8237) in Combination With Selective VEGFR Inhibitor Pazopanib for Therapy of Advanced Solid Tumors. Am J Clin Oncol. 2019 May; 42(5):413-420. PMID: 30973373.
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    2. Fong R, Wang L, Zacny JP, Khokhar S, Apfelbaum JL, Fox AP, Xie Z. Caffeine Accelerates Emergence from Isoflurane Anesthesia in Humans: A Randomized, Double-blind, Crossover Study. Anesthesiology. 2018 11; 129(5):912-920. PMID: 30044241.
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    3. Saba R, Alsayed A, Zacny JP, Dudek AZ. The Role of Forkhead Box Protein M1 in Breast Cancer Progression and Resistance to Therapy. Int J Breast Cancer. 2016; 2016:9768183. PMID: 26942015.
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    4. Ojevwe FO, Ojevwe CD, Zacny JP, Dudek AZ, Lin A, Kohlitz P. Treatment of multiple unresectable basal cell carcinomas from Gorlin-Goltz syndrome: a case report. Anticancer Res. 2015 Mar; 35(3):1777-81. PMID: 25750342.
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    5. Zacny JP, Wroblewski K, Coalson DW. Methylnaltrexone: its pharmacological effects alone and effects on morphine in healthy volunteers. Psychopharmacology (Berl). 2015 Jan; 232(1):63-73. PMID: 24871705.
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    6. O'Connor AB, Turk DC, Dworkin RH, Katz NP, Colucci R, Haythornthwaite JA, Klein M, O'Brien C, Posner K, Rappaport BA, Reisfield G, Adams EH, Balster RL, Bigelow GE, Burke LB, Comer SD, Cone E, Cowan P, Denisco RA, Farrar JT, Foltin RW, Haddox JD, Hertz S, Jay GW, Junor R, Kopecky EA, Leiderman DB, McDermott MP, Palmer PP, Raja SN, Rauschkolb C, Rowbotham MC, Sampaio C, Setnik B, Smith SM, Sokolowska M, Stauffer JW, Walsh SL, Zacny JP. Abuse liability measures for use in analgesic clinical trials in patients with pain: IMMPACT recommendations. Pain. 2013 Nov; 154(11):2324-34. PMID: 24148704.
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    7. Zacny JP, Apfelbaum SM, Perkins KA. Modulating roles of smoking status and sex on oxycodone-induced nausea and drug liking. Exp Clin Psychopharmacol. 2013 Apr; 21(2):103-11. PMID: 23421355.
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    8. Comer SD, Zacny JP, Dworkin RH, Turk DC, Bigelow GE, Foltin RW, Jasinski DR, Sellers EM, Adams EH, Balster R, Burke LB, Cerny I, Colucci RD, Cone E, Cowan P, Farrar JT, Haddox JD, Haythornthwaite JA, Hertz S, Jay GW, Johanson CE, Junor R, Katz NP, Klein M, Kopecky EA, Leiderman DB, McDermott MP, O'Brien C, O'Connor AB, Palmer PP, Raja SN, Rappaport BA, Rauschkolb C, Rowbotham MC, Sampaio C, Setnik B, Sokolowska M, Stauffer JW, Walsh SL. Core outcome measures for opioid abuse liability laboratory assessment studies in humans: IMMPACT recommendations. Pain. 2012 Dec; 153(12):2315-24. PMID: 22998781.
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    9. Turk DC, O'Connor AB, Dworkin RH, Chaudhry A, Katz NP, Adams EH, Brownstein JS, Comer SD, Dart R, Dasgupta N, Denisco RA, Klein M, Leiderman DB, Lubran R, Rappaport BA, Zacny JP, Ahdieh H, Burke LB, Cowan P, Jacobs P, Malamut R, Markman J, Michna E, Palmer P, Peirce-Sandner S, Potter JS, Raja SN, Rauschkolb C, Roland CL, Webster LR, Weiss RD, Wolf K. Research design considerations for clinical studies of abuse-deterrent opioid analgesics: IMMPACT recommendations. Pain. 2012 Oct; 153(10):1997-2008. PMID: 22770841.
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    10. Zacny JP, Paice JA, Coalson DW. Separate and combined psychopharmacological effects of alprazolam and oxycodone in healthy volunteers. Drug Alcohol Depend. 2012 Aug 01; 124(3):274-82. PMID: 22365897.
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    11. Zacny JP, Paice JA, Coalson DW. Subjective, psychomotor, and physiological effects of pregabalin alone and in combination with oxycodone in healthy volunteers. Pharmacol Biochem Behav. 2012 Jan; 100(3):560-5. PMID: 22085697.
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    12. Kircher S, Zacny J, Apfelbaum SM, Passik S, Kirsch K, Burbage M, Lofwall M. Understanding and treating opioid addiction in a patient with cancer pain. J Pain. 2011 Oct; 12(10):1025-31. PMID: 21968264.
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    13. Zacny J. Ask the Experts: What do we know (and not know) about prescription opioid misuse in the context of chronic pain management? Pain Manag. 2011 Sep; 1(5):395-8. PMID: 24645705.
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    14. Zacny JP, Paice JA, Coalson DW. Characterizing the subjective and psychomotor effects of carisoprodol in healthy volunteers. Pharmacol Biochem Behav. 2011 Nov; 100(1):138-43. PMID: 21884720.
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    15. Zacny JP, Paice JA, Coalson DW. Subjective and psychomotor effects of carisoprodol in combination with oxycodone in healthy volunteers. Drug Alcohol Depend. 2012 Jan 01; 120(1-3):229-32. PMID: 21840651.
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    16. Zacny JP, Gutierrez S. Subjective, psychomotor, and physiological effects of oxycodone alone and in combination with ethanol in healthy volunteers. Psychopharmacology (Berl). 2011 Dec; 218(3):471-81. PMID: 21603891.
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    17. Zacny JP, Gutierrez S, Kirulus K, McCracken SG. Psychopharmacological effects of oxycodone in volunteers with and without generalized anxiety disorder. Exp Clin Psychopharmacol. 2011 Apr; 19(2):85-94. PMID: 21463065.
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    18. Niesters M, Dahan A, Kest B, Zacny J, Stijnen T, Aarts L, Sarton E. Do sex differences exist in opioid analgesia? A systematic review and meta-analysis of human experimental and clinical studies. Pain. 2010 Oct; 151(1):61-8. PMID: 20692097.
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    19. Zacny JP, Jun JM. Lack of sex differences to the subjective effects of nitrous oxide in healthy volunteers. Drug Alcohol Depend. 2010 Dec 01; 112(3):251-4. PMID: 20667429.
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    20. Zacny JP. A possible link between sensation-seeking status and positive subjective effects of oxycodone in healthy volunteers. Pharmacol Biochem Behav. 2010 Mar; 95(1):113-20. PMID: 20045020.
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    21. Zacny JP, Drum M. Psychopharmacological effects of oxycodone in healthy volunteers: roles of alcohol-drinking status and sex. Drug Alcohol Depend. 2010 Mar 01; 107(2-3):209-14. PMID: 19948383.
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    22. Zacny JP, de Wit H. The prescription opioid, oxycodone, does not alter behavioral measures of impulsivity in healthy volunteers. Pharmacol Biochem Behav. 2009 Nov; 94(1):108-13. PMID: 19660489.
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    23. Zacny JP, Gutierrez S. Within-subject comparison of the psychopharmacological profiles of oral hydrocodone and oxycodone combination products in non-drug-abusing volunteers. Drug Alcohol Depend. 2009 Apr 01; 101(1-2):107-14. PMID: 19118954.
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    24. Zacny JP, Walker DJ, Derus LM. Choice of nitrous oxide and its subjective effects in light and moderate drinkers. Drug Alcohol Depend. 2008 Nov 01; 98(1-2):163-8. PMID: 18640794.
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    25. Zacny JP, Gutierrez S. Subjective, psychomotor, and physiological effects profile of hydrocodone/acetaminophen and oxycodone/acetaminophen combination products. Pain Med. 2008 May-Jun; 9(4):433-43. PMID: 18489634.
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    26. Comer SD, Ashworth JB, Foltin RW, Johanson CE, Zacny JP, Walsh SL. The role of human drug self-administration procedures in the development of medications. Drug Alcohol Depend. 2008 Jul 01; 96(1-2):1-15. PMID: 18436394.
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    27. Zacny JP, Walker DJ, Drum M, Sells M. Choice of sevoflurane and its subjective and psychomotor effects in light and moderate drinkers. Drug Alcohol Depend. 2008 Apr 01; 94(1-3):101-8. PMID: 18077105.
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    28. Zacny JP, Lichtor SA. Nonmedical use of prescription opioids: motive and ubiquity issues. J Pain. 2008 Jun; 9(6):473-86. PMID: 18342577.
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    29. Zacny JP, Lichtor SA. Within-subject comparison of the psychopharmacological profiles of oral oxycodone and oral morphine in non-drug-abusing volunteers. Psychopharmacology (Berl). 2008 Jan; 196(1):105-16. PMID: 17899018.
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    30. Zacny JP. Chronic pain and driving: proceed with caution. Pain. 2006 May; 122(1-2):6-7. PMID: 16530967.
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    31. Beckman NJ, Zacny JP, Walker DJ. Within-subject comparison of the subjective and psychomotor effects of a gaseous anesthetic and two volatile anesthetics in healthy volunteers. Drug Alcohol Depend. 2006 Jan 04; 81(1):89-95. PMID: 16024183.
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    32. Zacny JP. Profiling the subjective, psychomotor, and physiological effects of tramadol in recreational drug users. Drug Alcohol Depend. 2005 Nov 01; 80(2):273-8. PMID: 16005162.
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    33. Zacny J, Zamakhshary M, Sketris I, Veldhuyzen van Zanten S. Systematic review: the efficacy of intermittent and on-demand therapy with histamine H2-receptor antagonists or proton pump inhibitors for gastro-oesophageal reflux disease patients. Aliment Pharmacol Ther. 2005 Jun 01; 21(11):1299-312. PMID: 15932360.
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    34. Zacny JP. Differential effects of morphine and codeine on pupil size: dosing issues. Anesth Analg. 2005 Feb; 100(2):598; author reply 598. PMID: 15673906.
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    35. Zacny JP, Gutierrez S, Bolbolan SA. Profiling the subjective, psychomotor, and physiological effects of a hydrocodone/acetaminophen product in recreational drug users. Drug Alcohol Depend. 2005 Jun 01; 78(3):243-52. PMID: 15893155.
      View in: PubMed
    36. Walker DJ, Beckman NJ, Zacny JP. Reinforcing and subjective effects of the volatile anesthetic, sevoflurane. Drug Alcohol Depend. 2004 Nov 11; 76(2):191-201. PMID: 15488343.
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    37. Zacny JP, Beckman NJ. The effects of a cold-water stimulus on butorphanol effects in males and females. Pharmacol Biochem Behav. 2004 Aug; 78(4):653-9. PMID: 15301918.
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    38. Gutierrez S, Ang-Lee MK, Walker DJ, Zacny JP. Assessing subjective and psychomotor effects of the herbal medication valerian in healthy volunteers. Pharmacol Biochem Behav. 2004 May; 78(1):57-64. PMID: 15159134.
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    39. Zacny JP, Goldman RE. Characterizing the subjective, psychomotor, and physiological effects of oral propoxyphene in non-drug-abusing volunteers. Drug Alcohol Depend. 2004 Feb 07; 73(2):133-40. PMID: 14725952.
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    40. Zacny JP, Gutierrez S. Characterizing the subjective, psychomotor, and physiological effects of oral oxycodone in non-drug-abusing volunteers. Psychopharmacology (Berl). 2003 Nov; 170(3):242-254. PMID: 12955305.
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    41. Zacny J, Bigelow G, Compton P, Foley K, Iguchi M, Sannerud C. College on Problems of Drug Dependence taskforce on prescription opioid non-medical use and abuse: position statement. Drug Alcohol Depend. 2003 Apr 01; 69(3):215-32. PMID: 12633908.
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    42. Walker DJ, Zacny JP. Bitonic dose-response functions for reinforcing and self-reported effects of nitrous oxide in humans. Pharmacol Biochem Behav. 2003 Mar; 74(4):851-7. PMID: 12667899.
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    43. Zacny JP. Characterizing the subjective, psychomotor, and physiological effects of a hydrocodone combination product (Hycodan) in non-drug-abusing volunteers. Psychopharmacology (Berl). 2003 Jan; 165(2):146-56. PMID: 12404072.
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    44. Walker DJ, Zacny JP. Analysis of the reinforcing and subjective effects of different doses of nitrous oxide using a free-choice procedure. Drug Alcohol Depend. 2002 Mar 01; 66(1):93-103. PMID: 11850141.
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    45. Zacny JP, Hurst RJ, Graham L, Janiszewski DJ. Preoperative dental anxiety and mood changes during nitrous oxide inhalation. J Am Dent Assoc. 2002 Jan; 133(1):82-8. PMID: 11811748.
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    46. Walker DJ, Zacny JP. Lack of effects of ethanol pretreatment on the abuse liability of nitrous oxide in light and moderate drinkers. Addiction. 2001 Dec; 96(12):1839-45. PMID: 11784476.
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    47. Walker DJ, Zacny JP. Within- and between-subject variability in the reinforcing and subjective effects of nitrous oxide in healthy volunteers. Drug Alcohol Depend. 2001 Sep 01; 64(1):85-96. PMID: 11470344.
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    48. Zacny JP. Morphine responses in humans: a retrospective analysis of sex differences. Drug Alcohol Depend. 2001 Jun 01; 63(1):23-8. PMID: 11297828.
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    49. Walker DJ, Zacny JP, Galva KE, Lichtor JL. Subjective, psychomotor, and physiological effects of cumulative doses of mixed-action opioids in healthy volunteers. Psychopharmacology (Berl). 2001 Jun; 155(4):362-71. PMID: 11441425.
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    50. Draganich LF, Zacny J, Klafta J, Karrison T. The effects of antidepressants on obstructed and unobstructed gait in healthy elderly people. J Gerontol A Biol Sci Med Sci. 2001 Jan; 56(1):M36-41. PMID: 11193231.
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    51. Hill JL, Zacny JP. Comparing the subjective, psychomotor, and physiological effects of intravenous hydromorphone and morphine in healthy volunteers. Psychopharmacology (Berl). 2000 Sep; 152(1):31-9. PMID: 11041313.
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    52. Sadeghi P, Zacny JP. Anesthesia is a risk factor for drug and alcohol craving and relapse in ex-abusers. Med Hypotheses. 1999 Dec; 53(6):490-6. PMID: 10687890.
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    53. Zacny JP, Conran A, Pardo H, Coalson DW, Black M, Klock PA, Klafta JM. Effects of naloxone on nitrous oxide actions in healthy volunteers. Pain. 1999 Dec; 83(3):411-8. PMID: 10568848.
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    54. Zacny JP, Janiszewski D, Sadeghi P, Black ML. Reinforcing, subjective, and psychomotor effects of sevoflurane and nitrous oxide in moderate-drinking healthy volunteers. Addiction. 1999 Dec; 94(12):1817-28. PMID: 10717960.
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    55. Walker DJ, Zacny JP. Subjective, psychomotor, and physiological effects of cumulative doses of opioid mu agonists in healthy volunteers. J Pharmacol Exp Ther. 1999 Jun; 289(3):1454-64. PMID: 10336539.
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    56. Janiszewski DJ, Galinkin JL, Klock PA, Coalson DW, Pardo H, Zacny JP. The effects of subanesthetic concentrations of sevoflurane and nitrous oxide, alone and in combination, on analgesia, mood, and psychomotor performance in healthy volunteers. Anesth Analg. 1999 May; 88(5):1149-54. PMID: 10320186.
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    57. Black ML, Hill JL, Zacny JP. Behavioral and physiological effects of remifentanil and alfentanil in healthy volunteers. Anesthesiology. 1999 Mar; 90(3):718-26. PMID: 10078672.
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    58. Zacny JP, Galinkin JL. Psychotropic drugs used in anesthesia practice: abuse liability and epidemiology of abuse. Anesthesiology. 1999 Jan; 90(1):269-88. PMID: 9915336.
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    59. Walker DJ, Zacny JP. Subjective, psychomotor, and analgesic effects of oral codeine and morphine in healthy volunteers. Psychopharmacology (Berl). 1998 Nov; 140(2):191-201. PMID: 9860110.
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    60. Zacny JP, Camarillo VM, Sadeghi P, Black M. Effects of ethanol and nitrous oxide, alone and in combination, on mood, psychomotor performance and pain reports in healthy volunteers. Drug Alcohol Depend. 1998 Oct 01; 52(2):115-23. PMID: 9800141.
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    61. Zacny JP, Hill JL, Black ML, Sadeghi P. Comparing the subjective, psychomotor and physiological effects of intravenous pentazocine and morphine in normal volunteers. J Pharmacol Exp Ther. 1998 Sep; 286(3):1197-207. PMID: 9732379.
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    62. Zacny JP. Opioids and chronic pain. Clin J Pain. 1998 Mar; 14(1):89-90. PMID: 9535319.
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    63. Zacny JP, Cho AM, Toledano AY, Galinkin J, Coalson DW, Klock PA, Klafta JM, Young CJ. Effects of information on the reinforcing, subjective, and psychomotor effects of nitrous oxide in healthy volunteers. Drug Alcohol Depend. 1997 Nov 25; 48(2):85-95. PMID: 9363407.
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    64. Galinkin JL, Janiszewski D, Young CJ, Klafta JM, Klock PA, Coalson DW, Apfelbaum JL, Zacny JP. Subjective, psychomotor, cognitive, and analgesic effects of subanesthetic concentrations of sevoflurane and nitrous oxide. Anesthesiology. 1997 Nov; 87(5):1082-8. PMID: 9366460.
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    65. Zacny JP, Conley K, Galinkin J. Comparing the subjective, psychomotor and physiological effects of intravenous buprenorphine and morphine in healthy volunteers. J Pharmacol Exp Ther. 1997 Sep; 282(3):1187-97. PMID: 9316825.
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    66. Hasegawa AE, Zacny JP. The influence of three L-type calcium channel blockers on morphine effects in healthy volunteers. Anesth Analg. 1997 Sep; 85(3):633-8. PMID: 9296421.
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    67. Young CJ, Coalson D, Klock PA, Klafta JM, Goldsher G, Apfelbaum JL, Zacny JP. Analgesic and psychomotor effects of thiopental at subanesthetic concentrations in human volunteers. Acta Anaesthesiol Scand. 1997 Aug; 41(7):903-10. PMID: 9265935.
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    68. Conley KM, Toledano AY, Apfelbaum JL, Zacny JP. Modulating effects of a cold water stimulus on opioid effects in volunteers. Psychopharmacology (Berl). 1997 Jun; 131(4):313-20. PMID: 9226732.
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    69. Cho AM, Coalson DW, Klock PA, Klafta JM, Marks S, Toledano AY, Apfelbaum JL, Zacny JP. The effects of alcohol history on the reinforcing, subjective and psychomotor effects of nitrous oxide in healthy volunteers. Drug Alcohol Depend. 1997 Apr 14; 45(1-2):63-70. PMID: 9179508.
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    70. Zacny JP, Conley K, Marks S. Comparing the subjective, psychomotor and physiological effects of intravenous nalbuphine and morphine in healthy volunteers. J Pharmacol Exp Ther. 1997 Mar; 280(3):1159-69. PMID: 9067299.
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    71. Zacny JP, Mitchell SH, Cramblett MJ, de Wit H. The effects of ethanol on the relative preference for cigarettes. Behav Pharmacol. 1997 Feb; 8(1):75-81. PMID: 9833003.
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    72. Zacny JP. Should people taking opioids for medical reasons be allowed to work and drive? Addiction. 1996 Nov; 91(11):1581-4. PMID: 8972918.
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    73. Zacny JP, Klafta JM, Coalson DW, Marks S, Young CJ, Klock PA, Toledano AY, Jordan N, Apfelbaum JL. The reinforcing effects of brief exposures to nitrous oxide in healthy volunteers. Drug Alcohol Depend. 1996 Nov; 42(3):197-200. PMID: 8912802.
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    74. Zacny JP, Coalson DW, Klafta JM, Klock PA, Alessi R, Rupani G, Young CJ, Patil PG, Apfelbaum JL. Midazolam does not influence intravenous fentanyl-induced analgesia in healthy volunteers. Pharmacol Biochem Behav. 1996 Oct; 55(2):275-80. PMID: 8951965.
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    75. Zacny JP, McKay MA, Toledano AY, Marks S, Young CJ, Klock PA, Apfelbaum JL. The effects of a cold-water immersion stressor on the reinforcing and subjective effects of fentanyl in healthy volunteers. Drug Alcohol Depend. 1996 Oct; 42(2):133-42. PMID: 8889412.
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    76. Zacny JP, Coalson DW, Young CJ, Klafta JM, Lichtor JL, Rupani G, Thapar P, Apfelbaum JL. Propofol at conscious sedation doses produces mild analgesia to cold pressor-induced pain in healthy volunteers. J Clin Anesth. 1996 Sep; 8(6):469-74. PMID: 8872686.
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    77. Yajnik S, Zacny JP, Young CJ, Lichtor JL, Rupani G, Klafta JM, Coalson DW, Apfelbaum JL. Lack of acute tolerance development to the subjective, cognitive, and psychomotor effects of nitrous oxide in healthy volunteers. Pharmacol Biochem Behav. 1996 Jun; 54(2):501-8. PMID: 8743615.
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    78. Zacny JP, Cho AM, Coalson DW, Rupani G, Young CJ, Klafta JM, Klock PA, Apfelbaum JL. Differential acute tolerance development to effects of nitrous oxide in humans. Neurosci Lett. 1996 May 10; 209(2):73-6. PMID: 8761985.
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    79. Zacny JP, Lichtor JL, Klafta JM, Alessi R, Apfelbaum JL. The effects of transnasal butorphanol on mood and psychomotor functioning in healthy volunteers. Anesth Analg. 1996 May; 82(5):931-5. PMID: 8610901.
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    80. Lichtor JL, Zacny J, Lane BS, Good ML. Research grant report: how does night call affect next-day performance in anesthesia? J Clin Monit. 1996 May; 12(3):277-8. PMID: 8823653.
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    81. Zacny JP, Lichtor JL, Coalson DW, Alessi R, Goldsher G, Young CJ, Apfelbaum JL, Conley KM. Examining the subjective, psychomotor and reinforcing effects of nitrous oxide in healthy volunteers: a dose-response analysis. Behav Pharmacol. 1996 Mar; 7(2):194-199. PMID: 11224411.
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    82. Zacny JP, Yajnik S, Lichtor JL, Klafta JM, Young CJ, Thapar P, Rupani G, Coalson DW, Apfelbaum JL. The acute and residual effects of subanesthetic concentrations of isoflurane/nitrous oxide combinations on cognitive and psychomotor performance in healthy volunteers. Anesth Analg. 1996 Jan; 82(1):153-7. PMID: 8712393.
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    83. Patil PG, Apfelbaum JL, Zacny JP. Effects of a cold-water stressor on psychomotor and cognitive functioning in humans. Physiol Behav. 1995 Dec; 58(6):1281-6. PMID: 8623033.
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    84. Klafta JM, Zacny JP, Young CJ. Neurological and psychiatric adverse effects of anaesthetics: epidemiology and treatment. Drug Saf. 1995 Nov; 13(5):281-95. PMID: 8785016.
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    85. Zacny JP, Lichtor JL, Coalson DW, Apfelbaum JL. Nitrous oxide and the terminology of 'abuse' and 'use'. Addiction. 1995 Sep; 90(9):1265-6. PMID: 7580824.
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    86. Zacny JP, Yajnik S, Coalson D, Lichtor JL, Apfelbaum JL, Rupani G, Young C, Thapar P, Klafta J. Flumazenil may attenuate some subjective effects of nitrous oxide in humans: a preliminary report. Pharmacol Biochem Behav. 1995 Aug; 51(4):815-9. PMID: 7675863.
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    87. Mitchell SH, de Wit H, Zacny JP. Caffeine withdrawal symptoms and self-administration following caffeine deprivation. Pharmacol Biochem Behav. 1995 Aug; 51(4):941-5. PMID: 7675881.
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    88. Thapar P, Zacny JP, Choi M, Apfelbaum JL. Objective and subjective impairment from often-used sedative/analgesic combinations in ambulatory surgery, using alcohol as a benchmark. Anesth Analg. 1995 Jun; 80(6):1092-8. PMID: 7762835.
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    89. Mitchell SH, de Wit H, Zacny JP. Effects of varying ethanol dose on cigarette consumption in healthy normal volunteers. Behav Pharmacol. 1995 Jun; 6(4):359-365. PMID: 11224344.
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    90. Pirec V, Patterson TH, Thapar P, Apfelbaum JL, Zacny JP. Effects of subanesthetic concentrations of nitrous oxide on cold-pressor pain in humans. Pharmacol Biochem Behav. 1995 Jun-Jul; 51(2-3):323-9. PMID: 7667348.
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    91. Zacny JP, Coalson D, Young C, Klafta J, Rupani G, Thapar P, Choi M, Apfelbaum JL. A dose-response study of the effects of intravenous midazolam on cold pressor-induced pain. Anesth Analg. 1995 Mar; 80(3):521-5. PMID: 7864418.
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    92. Thapar P, Zacny JP, Thompson W, Apfelbaum JL. Using alcohol as a standard to assess the degree of impairment induced by sedative and analgesic drugs used in ambulatory surgery. Anesthesiology. 1995 Jan; 82(1):53-9. PMID: 7832334.
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    93. Yajnik S, Thapar P, Lichtor JL, Patterson T, Zacny JP. Effects of marijuana history on the subjective, psychomotor, and reinforcing effects of nitrous oxide in humans. Drug Alcohol Depend. 1994 Dec; 36(3):227-36. PMID: 7889814.
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    94. Zacny JP, Coalson DW, Lichtor JL, Yajnik S, Thapar P. Effects of naloxone on the subjective and psychomotor effects of nitrous oxide in humans. Pharmacol Biochem Behav. 1994 Nov; 49(3):573-8. PMID: 7862710.
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    95. Doty P, Zacny JP, de Wit H. Effects of ondansetron pretreatment on acute responses to ethanol in social drinkers. Behav Pharmacol. 1994 Aug; 5(4 And 5):461-469. PMID: 11224298.
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    96. Zacny JP, Lichtor JL, Thapar P, Coalson DW, Flemming D, Thompson WK. Comparing the subjective, psychomotor and physiological effects of intravenous butorphanol and morphine in healthy volunteers. J Pharmacol Exp Ther. 1994 Aug; 270(2):579-88. PMID: 8071850.
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    97. Zacny JP, Lichtor JL, Coalson DW, Apfelbaum JL, Flemming D, Foster V. Time course of effects of brief inhalations of nitrous oxide in normal volunteers. Addiction. 1994 Jul; 89(7):831-9. PMID: 8081181.
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    98. Mitchell SH, de Wit H, Zacny JP. Effects of varying the "openness" of an economy on responding for cigarettes. Behav Pharmacol. 1994 Apr; 5(2):159-166. PMID: 11224264.
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    99. Zacny JP, Sparacino G, Hoffmann P, Martin R, Lichtor JL. The subjective, behavioral and cognitive effects of subanesthetic concentrations of isoflurane and nitrous oxide in healthy volunteers. Psychopharmacology (Berl). 1994 Apr; 114(3):409-16. PMID: 7855199.
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    100. Zacny JP, Lichtor JL, Flemming D, Coalson DW, Thompson WK. A dose-response analysis of the subjective, psychomotor and physiological effects of intravenous morphine in healthy volunteers. J Pharmacol Exp Ther. 1994 Jan; 268(1):1-9. PMID: 8301543.
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    101. Dohrn CS, Lichtor JL, Coalson DW, Flemming D, Zacny JP. Reinforcing effects of extended inhalation of a low nitrous oxide concentration in humans. Pharmacol Biochem Behav. 1993 Dec; 46(4):927-32. PMID: 8309974.
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    102. Zacny JP, Yajnik S. Effects of calcium channel inhibitors on ethanol effects and pharmacokinetics in healthy volunteers. Alcohol. 1993 Nov-Dec; 10(6):505-9. PMID: 8123209.
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    103. Wang WL, Cone EJ, Zacny J. Immunoassay evidence for fentanyl in hair of surgery patients. Forensic Sci Int. 1993 Sep; 61(1):65-72. PMID: 8225140.
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    104. Zacny JP, Lichtor JL, Thompson W, Apfelbaum JL. Propofol at a subanesthetic dose may have abuse potential in healthy volunteers. Anesth Analg. 1993 Sep; 77(3):544-52. PMID: 8368554.
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    105. Lichtor JL, Zacny JP, Coalson DW, Flemming DC, Uitvlugt A, Apfelbaum JL, Lane BS, Thisted RA. The interaction between alcohol and the residual effects of thiopental anesthesia. Anesthesiology. 1993 Jul; 79(1):28-35. PMID: 8342825.
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    106. Zacny JP, Lichtor JL, Zaragoza JG, Coalson DW, Uitvlugt AM, Flemming DC, Binstock WB, Cutter T, Apfelbaum JL. Assessing the behavioral effects and abuse potential of propofol bolus injections in healthy volunteers. Drug Alcohol Depend. 1993 Mar; 32(1):45-57. PMID: 8486084.
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    107. Dohrn CS, Lichtor JL, Coalson DW, Uitvlugt A, de Wit H, Zacny JP. Reinforcing effects of extended inhalation of nitrous oxide in humans. Drug Alcohol Depend. 1993 Feb; 31(3):265-80. PMID: 8462415.
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    108. Zacny JP, Apfelbaum JL, Lichtor JL, Zaragoza JG. Effects of 5-hydroxytryptamine3 antagonist, ondansetron, on cigarette smoking, smoke exposure, and mood in humans. Pharmacol Biochem Behav. 1993 Feb; 44(2):387-91. PMID: 8446670.
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    109. Zacny JP, Lichtor JL, Binstock W, Coalson DW, Cutter T, Flemming DC, Glosten B. Subjective, behavioral and physiological responses to intravenous meperidine in healthy volunteers. Psychopharmacology (Berl). 1993; 111(3):306-14. PMID: 7870968.
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    110. Zacny JP, Lichtor JL, Coalson DW, Finn RS, Uitvlugt AM, Glosten B, Flemming DC, Apfelbaum JL. Subjective and psychomotor effects of subanesthetic doses of propofol in healthy volunteers. Anesthesiology. 1992 May; 76(5):696-702. PMID: 1575336.
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    111. Zacny JP, Lichtor JL, de Wit H. Subjective, behavioral, and physiologic responses to intravenous dezocine in healthy volunteers. Anesth Analg. 1992 Apr; 74(4):523-30. PMID: 1348168.
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    112. Dohrn CS, Lichtor JL, Finn RS, Uitvlugt A, Coalson DW, Rupani G, de Wit H, Zacny JP. Subjective and psychomotor effects of nitrous oxide in healthy volunteers. Behav Pharmacol. 1992 Feb; 3(1):19-30. PMID: 11224098.
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    113. Zacny JP, Lichtor JL, Zaragoza JG, de Wit H. Subjective and behavioral responses to intravenous fentanyl in healthy volunteers. Psychopharmacology (Berl). 1992; 107(2-3):319-26. PMID: 1615132.
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    114. Zacny JP, Bodker BK, de Wit H. Effects of setting on the subjective and behavioral effects of d-amphetamine in humans. Addict Behav. 1992; 17(1):27-33. PMID: 1595423.
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    115. Zacny JP, de Wit H. The effects of a restricted feeding regimen on cigarette smoking in humans. Addict Behav. 1992; 17(2):149-57. PMID: 1585842.
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    116. Chait LD, Zacny JP. Reinforcing and subjective effects of oral delta 9-THC and smoked marijuana in humans. Psychopharmacology (Berl). 1992; 107(2-3):255-62. PMID: 1319601.
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    117. Zacny JP, Lichtor JL, Zaragoza JG, de Wit H. Effects of fasting on responses to intravenous fentanyl in healthy volunteers. J Subst Abuse. 1992; 4(2):197-207. PMID: 1504643.
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    118. Evans SM, Zacny JP, Woolverton WL, Johanson CE. The discriminative stimulus effects of histamine H(1)-antagonists in pigeons. Behav Pharmacol. 1991 Dec; 2(6):447-460. PMID: 11224087.
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    119. Lichtor JL, Zacny J, Apfelbaum JL, Lane BS, Rupani G, Thisted RA, Dohrn C, Korttila K. Alcohol after sedation with i.v. midazolam-fentanyl: effects on psychomotor functioning. Br J Anaesth. 1991 Nov; 67(5):579-84. PMID: 1751272.
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    120. Zacny JP, de Wit H. Effects of food deprivation on subjective effects and self-administration of marijuana in humans. Psychol Rep. 1991 Jun; 68(3 Pt 2):1263-74. PMID: 1924625.
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    121. Lichtor JL, Zacny J, Korttila K, Apfelbaum JL, Lane BS, Rupani G, Thisted RA, Dohrn C. Alcohol after midazolam sedation: does it really matter? Anesth Analg. 1991 May; 72(5):661-6. PMID: 2018224.
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    122. Zacny JP, Chait LD. Response to marijuana as a function of potency and breathhold duration. Psychopharmacology (Berl). 1991; 103(2):223-6. PMID: 2027922.
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    123. Evans SM, Zacny JP, Johanson CE. Three-choice discrimination among (+)-amphetamine, fenfluramine and saline in pigeons. Pharmacol Biochem Behav. 1990 Apr; 35(4):971-80. PMID: 1971722.
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    124. Zacny JP, de Wit H. Effects of a 24-hour fast on cigarette smoking in humans. Br J Addict. 1990 Apr; 85(4):555-60. PMID: 2346795.
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    125. Zacny JP, Virus RM, Woolverton WL. Tolerance and cross-tolerance to 3,4-methylenedioxymethamphetamine (MDMA), methamphetamine and methylenedioxyamphetamine. Pharmacol Biochem Behav. 1990 Mar; 35(3):637-42. PMID: 1971112.
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    126. Zacny JP. Behavioral aspects of alcohol-tobacco interactions. Recent Dev Alcohol. 1990; 8:205-19. PMID: 2185518.
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    127. Zacny JP, Chait LD. Response to marijuana as a function of potency and breathhold duration. NIDA Res Monogr. 1990; 105:308-9. PMID: 1652073.
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    128. Zacny JP, de Wit H. Effects of food deprivation on subjective responses to d-amphetamine in humans. Pharmacol Biochem Behav. 1989 Dec; 34(4):791-5. PMID: 2623032.
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    129. Zacny JP, Woolverton WL. Discriminative stimulus properties of local anesthetics in d-amphetamine- and pentobarbital-trained pigeons. Pharmacol Biochem Behav. 1989 Jul; 33(3):527-31. PMID: 2587593.
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    130. Zacny JP, Chait LD. Breathhold duration and response to marijuana smoke. Pharmacol Biochem Behav. 1989 Jun; 33(2):481-4. PMID: 2554344.
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    131. Zacny J, de Wit H. Effects of food deprivation on subjective responses to d-amphetamine and marijuana in humans. NIDA Res Monogr. 1989; 95:490-1. PMID: 2701322.
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    132. Zacny JP, de Wit H. Effects of food deprivation on responses to marijuana in humans. Behav Pharmacol. 1989; 1(2):177-185. PMID: 11175401.
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    133. Zacny JP. Discriminative stimulus effects of H(1)-anti-histamines in cocaine-trained pigeons. Behav Pharmacol. 1989; 1(3):261-265. PMID: 11224038.
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    134. Zacny JP, Stitzer ML. Cigarette brand-switching: effects on smoke exposure and smoking behavior. J Pharmacol Exp Ther. 1988 Aug; 246(2):619-27. PMID: 3404450.
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    135. Zacny JP, Stitzer ML, Brown FJ, Yingling JE, Griffiths RR. Human cigarette smoking: effects of puff and inhalation parameters on smoke exposure. J Pharmacol Exp Ther. 1987 Feb; 240(2):554-64. PMID: 3806411.
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    136. Zacny JP, Stitzer ML, Yingling JE. Cigarette filter vent blocking: effects on smoking topography and carbon monoxide exposure. Pharmacol Biochem Behav. 1986 Dec; 25(6):1245-52. PMID: 3809227.
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    137. Zacny JP, Stitzer ML. Effect of puff size instructions on puff volume. Addict Behav. 1986; 11(1):17-23. PMID: 3716912.
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    138. Zacny JP, Stitzer ML. Effects of smoke deprivation interval on puff topography. Clin Pharmacol Ther. 1985 Jul; 38(1):109-15. PMID: 4006371.
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    139. Goodman I, Zacny J, Osman A, Azzaro A, Donovan C. Dopaminergic nature of feeding-induced behavioral stereotypies in stressed pigeons. Pharmacol Biochem Behav. 1983 Feb; 18(2):153-8. PMID: 6682226.
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    140. Goodman I, Zacny J, Osman A, Azzaro A, Donovan C. Lesion-produced telencephalic catecholamine imbalances and altered operant pecking rates in pigeons. Physiol Behav. 1982 Dec; 29(6):1045-50. PMID: 7163383.
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